Histidine: ifomula, ekudibaneni kwemichiza

Ngamnye kuthi ubuncinane kanye ebomini wacinga ukudla kwakhe. Apha, umzekelo, into eqhelekileyo yemihla ngemihla kwezinto ezahlukeneyo ezifunekayo yi umzimba uza kuthi ngayo ukutya? Yintoni acid sifuna, yaye yintoni? Namhlanje, thina, Kakade ke, makhe thetha malunga nokutya okusempilweni luphela, ekubeni lo mncinane kunye namanqaku nkqu elinesibini. Siya ndithi into enye kuphela, nto leyo ngokungathandabuzekiyo kubaluleke kakhulu ukuba umzimba. Oku acid histidine asidi. igama layo chemical izandi nzima - L-2-acid-3- (1H-imidazol-4-yl) propanoic acid. Kodwa izinto zokuqala kuqala.

Yintoni acid?

Ngaphambi kokuba sixoxe iimpawu histidine kunye nendima yayo emzimbeni, siya baqonde elithi "acid acid". Abo babekuthanda ezemidlalo, sivile malunga ezi izinto. An acid acid yi ulungelelwaniso ukuba amaqela amabini ezisisiseko ezisebenzayo ezenza kube ezizodwa: group acid i -NH _2, wabiza njalo-iqela carboxyl -COOH.

Eyokuqala linoxanduva iimpawu engundoqo yolu didi angaqhelekanga iikhompawundi. Ngenxa nitrogen kunye electron yayo isibini acid acid kungenzeka kakuhle icala ion. Xa iqela acid iguqulelwa apha loo ion: -NH ₃ ^+.

Iqela esebenzayo yesibini uxanduva iipropati asidi. Kuyinto olukwazi ekunikeleni a Proton, abe anion -COO ^-. Loo meko yenza iityuwa ukwakha neqela kwicala carboxyl.

Ngenxa yoko, i-asidi acid inamacandelo amabini, ngamnye ezinako wokusungula neetyuwa. Omnye wabo inika iimpawu ezi zihlanganisi, ii-asidi, kunye nezinye - amabala. Ngokubanzi, i-asidi acid angamelwa njenge: H. ₂ -CH (R) -COOH. Ileta R ukuze ziqondwe apha 'ezinkulu ", ngamanye nayiphi isuntswana zomgquba ebandakanya amaqela ezisebenzayo kunye skeleton carbon nabanako zokubumba ibhondi (okanye imixokelelwane) ukuya zeendawana yomoya acid acid.

Njengomgaqo, nkqu nabo akazazi Pharmacology kwaye akanamdla kwezemidlalo, Ndakha ndeva, ubuncinane kwezentengiso, ukuba acid kufuneka thina, kwaye iluncedo kakhulu. Makhe sibone ukuba yintoni umsebenzi abasenzela emzimbeni yaye kutheni kufuneka ufumane kubo isantya efunekayo ukutya.

Amino acids umsebenzi emzimbeni

Njengoko usazi, sonke enziwa iiprothini, amafutha kunye carbohydrate. Kwaye njengoko ndiligqibele ukutya ukugcina nokusebenza kwayo. Kodwa ke isihloko eli nqaku, senza banomdla iiproteni kuphela. Le molecule enkulu, enze imisebenzi eyahlukileyo ngokupheleleyo kwaye kubaluleke kakhulu emzimbeni wethu: zothutho izinto, ukudalwa iiseli ezintsha, ekomelezeni amakhonkco phakathi luvo ebuchotsheni. esithetha ngayo akukho iiproteni nje. Isibakala sokuba zonke ezi zinto zenziwe asidi acid, nto leyo enokubandakanya histidine. Ifomula nkqu nezo elula liquka asidi ubuncinane ezilishumi acid, lidibane nomxokelelwane polypeptide. Ngamnye kubo isakhiwo yayo nemilo evumela ukuba enze umsebenzi apho yayiyilwe yi ngokwemvelo.

histidine

Ifomula kuquka nawuphi na acid acid, njengoko sele sibonile, amaqela ubuncinane ezimbini ezisebenzayo kunye amathambo carbon, ukudibanisa kuwo. Kungenxa yoko le nto umahluko phakathi zonke acid (leyo, ngokuzenzekelayo, sele wafumana yesigidi ezimbalwa) ubude kwebhulorho carbon phakathi kwala maqela mabini kubume ngokupheleleyo, adjoint kuyo.

Umxholo wale nqaku - yenye acid - histidine. Formula le lwenkonzo acid nzima. Chain carbon ophambili phakathi kwala maqela mabini ezisebenzayo sibona kuphela carbon atom enye. Enyanisweni, bonke proteinogenic ebalulekileyo (ezinako ukudala iiprothini) acid Kwakhona kuphela omnye carbon atom kwi kwikhonkco. Ngaphezu koko, histidine na isakhiwo elukhuni kumjikelo okubandakanya olukhulu. Ngaphezu ungabona leyo histidine. Ifomula, noshowo inkalo enala kwi heterocycle (kuqukwa naziphi na ezinye atom ngaphandle carbon), ngenene na le nto inzima.

Ngoko ke, xa siye saxubusha nezimaphambili ezingundoqo, makhe bafudukele abasabela enokwenziwa ngokwazo kunye histidine.

iipropati chemical

Reaction, nto leyo ethatha le asidi acid, Kuyinto inqabile. Eminye ukusabela isakudityaniswa nee-asidi, neziseko zayo, ingena kungena indlela biuret ukwenza iimveliso bebala. Ngaphezu koko, histidine, ogama ifomula kuquka intsalela ye imidazole ukuze awasabela ngayo kunye sulphanilic acid uPauli basabela.

isiphelo

Mhlawumbi zonke ke izinto enkulu ngabunye. Siyathemba ukuba nqaku waba luncedo kakhulu kuwe, akunike ulwazi olutsha.