"Indomethacin" (tablets): imiyalelo, real

Enye abameli zelo qela nonsteroidal amachiza-ukudumba sisiyobisi "Indomethacin" (tablets). Ngenxa yayo anti-ukudumba, iintlungu kunye neziphumo antipyretic ngokusebenzisa yayo ngenxa unyango lwezifo ukudumba, kuphele iintlungu, ukunciphisa ukudumba kunye nokubuyisela ukushukumiseka ngokudibeneyo.

Inkcazelo yokulungiselela

Eyona nto iphambili ebonakalayo ichiza indomethacin, ezo zinxulumene indole yezabelo acid acetic. Ngaphakathi upakisha medicament "Indomethacin" ichaza njengezinto amacwecwe sikhokelo kunye ukutyabeka ama yokhuselo oluvumela arhente esebenzayo ukukhululwa ethunjini, ngokudlula isisu. Imilo iipilisi ngeenxa zonke, biconvex, phezulu ugqunywe kwiqokobhe kukukhanya-mdaka.

Iipilisi kukho iidosi ezininzi: 25 mg, 50 mg kunye 100 mg indomethacin. Ifumaneka iziqwenga ezili-10 okanye ama-40 pack nganye.

Zonke iifom balawule

Koko tablets, kukho ezinye iindlela "Indomethacin" ukulungiselela ukusetyenziswa yomlomo, umzekelo ezinzileyo ukukhululwa philisi umthamo 75 mg. Ukuze ulawulo efakwa, suppositories zisetyenziswa kunye ne nedosi ye-50 mg. Kuba izicelo ngaphandle udale ngamafutha-5% ne-10% ne-3% gel.

indlela isenzo

Le medicament i antiinflammatory nonsteroidal arhente inyathelo systemic, nto leyo eye antiinflammatory, ukuqumba, iintlungu kunye neziphumo antipyretic. Okuqhotyoshelwe ichiza kwendlela "Indomethacin" (tablets) isikhokelo iqulathe inkcazelo ukusebenza kwawo isithako esebenzayo enxulumene ukuncipha umsebenzi cyclooxygenase lwe-1 no-2. Kwelinye icala, lo enzyme kunempembelelo oluncinane CD leyo kunciphisa ukuguquka kwalo prostaglandin. Ezi izinto ezibangela nokudumba kunye neentlungu.

imiboniso Indomethacin antiplatelet ukusebenza, ukunciphisa zegazi clumping kweeseli zegazi. Iziyobisi attenuates intlungu kwi intlungu ndibanisela zikwimeko ezolileyo mobile, kunciphisa kusasa ukuqina kunye ukudumba, kwandisa uluhlu motion. Amanyathelo indomethacin ezijoliswe ekunciphiseni komtshiso oko. Isiphumo esiphezulu linikwa ngomhla wesixhenxe konyango, amacwecwe iziyobisi.

loo ngxabano

Ngokusekelwe indlela yokusebenza, "Indomethacin" icwecwe yemiyalezo uncoma ukusebenzisa unyango lwenkqubo:

• syndrome articular;
• izifo yokukrala kwenkqubo musculoskeletal ezibangelwa samathambo, psoriatic, samathambo, samathambo mthetho ongumntwana, igxalaba engumkhenkce, ankylosing spondylitis, isifo elidityanelweyo deforming osteitis kunye uretrookulosinovialnom syndrome;
• izifo sisiba mandundu kwenkqubo musculoskeletal ezibangelwa osteochondrosis kunye radicular syndrome, osteoarthrosis namalungu, ngaphandle inyonga arthrosis intervertebral;
• kuyenye yeendlela izifo, bagqume kwizicwili;
• rheumatism;
• izilonda suppurative yokukrala kwiingxowa periarticular kunye nemisipha;
• Iimpawu ahlekise ngasemva ezisezantsi kunye nezinye iinxalenye emqolo xa neuralgia sciatic kunye nezinye luvo, ukudumba izihlunu;
• ukudumba lakha ancedisana ezithambileyo okanye amalungu.

Xi nga ku pfuna ku langutana yintloko ebuhlungu, sexesheni, bamazinyo, isifo sephepha.

Njenge-arhente abangabancedani kwezifo ezosulelayo kunye ukudumba ezifana pharyngitis, tonsils, otitis usebenzisa medicament "Indomethacin" (tablets). Ubungqina obubonakalayo buxela ziquka unyango lwe Ngokuzimela, adnexitis, prostatitis.

Ichiza kakuhle zokususa syndrome febrile ezinxulumene nesifo Hodgkin kaThixo, lymphoma, nangezilonda kuwenza, xa zazixakekile paracetamol kunye acetyl salicylic acid.

Indlela ukuthatha

"Indomethacin" amayeza emacwecweni yenziwa njengesigulana idosi ethile esekelwe iqondo sifo. Ngokuqhelekileyo, abantu abadala ziqala ukufumana umthamo we-25 mg kathathu ngemini emva kokutya.

Ukuba isiphumo unyango ayoneli iqapheleka idosi kabini ukuya kuma-50 mg 3 amaxesha ngosuku. ithamo Ubukhulu sivumelekile ukuba ngaphezu 200 mg indomethacin. Emva ukuphucuka okukhulu okubangelwa unyango iziyobisi, unyango kufuneka simiswe iiveki kuphela emva 4 besebenzisa ixesha elidlulileyo okanye umthamo lincitshiswe. Ukuba izigulane ukuthatha iipilisi ixesha elide "Indomethacin" yemiyalezo lithethelela ukuba ithamo-75 mg Isithako esisebenzayo ngamnye ngosuku.

ukuphathwa kwabantwana

Ukuze umntwana idosi yemihla ngemihla kubalwa phinda 2.5 okanye 3 mg ubunzima emzimbeni wakhe, ithinjiwe iKiriyatayim kumaxesha 3-4. Kwiqela lobudala ngalinye yanika ukusetyenziswa kwe-idosi yokuqala yemihla ngemihla:

• abantwana 3 ukuya kwiminyaka-7 maliqhutywe ukuqalela nge-50 mg ukuya 75 mg, engqamana amacwecwe-2 okanye ezi-3;
• abantwana 7 ukuya kweli-12: ukusuka kuma-75 mg ukuya 100 mg, okuhambelana amacwecwe-3 okanye ezi-4;
• Abantwana abaneminyaka 12 ezibekwa 100 mg ukuya 125 mg, engqamana amacwecwe-4 okanye 5.

Kwiintsuku zokuqala ezimbalwa, kukufumana indlela ichiza emzimbeni komntwana, ngoko ke sebenzisa igcuntswana leyeza amayeza. Ubude unyango with "Indomethacin" (tablets) umyalelo yayimisela nexesha ukusuka kwiintsuku ezi-6 ukuya kwesi-7.

iimpawu reception

Kulo mba, kukho amathuba neziphumo ezibi ukwamkelwa lithetha "Indomethacin" emacwecweni, kungcono ukuba ukuyisebenzisa ngenxa yonyango samathambo etsolo ebuntwaneni. Kuqhubeka ukuba ubisi lwebele, eyona nto esebenzayo lingena kwigazi zosana, kwandisa senyongo komzimba kwi usana kunye ngokoyiswa iiseli zesibindi. Ukuze uphephe oku, khansela nokuncancisa.

Abadala, izigulane isibindi ababesifa, izintso, wokugaya, iimpawu dyspeptic, lwegazi, ukusilela intliziyo congestive emva kotyando, isifo Parkinson kaThixo, sokuwa, wamitha kwi I II ezintathu xa kufuneka anike unyango Indomethacin ukuba esweni iwonga eziphilayo. Kuyimfuneko ukulawula umsebenzi wamalungu eziyingxaki, kanye yonke imihla 7 ukuze bahlole igazi peripheral.

Ukuba ngaphambili umzimba ukuya non-steroidal amachiza anti-ukudumba, ichiza "Indomethacin" (tablets) emiselwa kwiimeko kakhulu.

Asazi singacebisi enza umsebenzi enobungozi unyango, njengoko ingqalelo kunye lengqondo umsebenzi uphazanyiswa.

Xa ungakwazi ukuthatha

Kukho izifo apho amayeza contraindicated "Indomethacin" (tablets). ukusetyenziswa kwalo akwenzeki:

• hypersensitivity ku indomethacin;
• phambi ilunga nangokujaduka sisilonda yenkqubo zokwetyisa kwisigaba oyingozi;
• xa "aspirin triad", esibonakala ukunyamezelana ukuya acetylsalicylic acid, polyp ngeempumlo kunye isifuba inyumoniya;
• e hemodyscrasia;
• xa ukuguquguquka wesibindi, nezintso;
• kwi nokubambezeleka neetyuwa kunye ezilulwelo kunye nokudumba kunokwenzeka peripheral;
• obunzima ukusilela ezingapheliyo nesimilo myocardium;
• ngamandla siphakamileyo;
• isifuba inyumoniya;
• e ukudumba pancreas;
• kwithuba leenyanga ezintathu III sokukhulelwa umntwana;
• ibele;
• kubantwana abancinane ngaphezu kweminyaka emi-3.

ukusabela ezingalunganga

Amayeza "Indomethacin" (tablets) esinxulunyaniswa kunye iziganeko ezibi luchaphazela imeko umzimba womntu. Basabele eziqhelekileyo ezingalunganga iquka isicaphucaphu, ukudla, iintlungu esiswini, ukuqumba, ukuqhina, ukungacoleki kokutya.

Kwiimeko ezinqabe kakhulu, ziphumo bezingalindelekanga kwenzeka ilunga nangokujaduka sisilonda, ukopha kunye perforation esiswini neendonga emathunjini; applasticheskoy okanye igazi hemolytic, leukopenia, thrombocytopenia, agranulocytosis, irhashalala, ilahleko iinwele, isikhumba ukurhawuzelela, ukuxhuzula, angioedema, bronchospasm.

Iimpawu ayingozi epidermal necrolysis, kunqabile kakhulu wabona mothuko anaphylactic, erythema nodosum.

Ngexesha unyango kuthi kuphazamisane ukusebenza kwezintso excretory kunye wesibindi, nto leyo eyandisa isixa yibilirubin, transaminases hepatic.

ukusetyenziswa lwexesha elide ichiza "Indomethacin" (tablets) akukhethi reactions emibi kunye nokuphazamiseka, isiyezi, peripheral neuropathy, intloko ebuhlungu, ukuphazamiseka, ukuba nochuku, ukudinwa. Bona luphawulwa clouding lo inwebu, conjunctivitis, ukungase-, ukuduma, lwegazi, nokudumba.

reviews

Kubalulekile ukulandela yonke imithetho ichiza, ngaphandle zonke Izimo.

Zixubene malunga nokwamkelwa "Indomethacin" ncomo iziyobisi. Ezipilisi zineziphumo ngaphezu iifom esithathwa ukusetyenziswa lwangaphandle. Ngaphezu koko, iziyobisi esebenzayo kunxulumene inhibitors of cyclo-oxygenase 1 no-2, nto leyo zithathwa ngempumelelo ngaphantsi zibangele inani ngayo engathandekiyo le gastro-emathunjini phecana.

Rheumatologists kunye nezigulane zabo, oogqirha badla amisele amachiza amatsha ukusuka kwiqela oxicams. Bona zinqanda uhlobo cyclooxygenase-2 kuphela, ngaphandle kokuchaphazela uhlobo enzyme 1, eqinisekisa imveliso prostaglandins akhusela inkqubo yokwetyisa. Kungenxa yoko le nto oxicams ukwenza okubi kangako esiswini kunokunyanga "Indomethacin" (tablets). Imiyalelo ingxelo embi kuquka inkcazelo ziziphumo ebezingalindelekanga, kodwa oku akuthethi ukuba unyango kufuneka iboniswe. Yonke into ixhomekeke iimpawu eziphilayo.

izigulane ezininzi, oku kuthetha ukonga xa eminye imithi musa uncedo iqolo, myalgia, neuralgia intercostal,. A imiphumela emibi phantse musa uvuke unyango "Indomethacin" iziyobisi. Izimvo amacwecwe wachacha izigulane emihle. Nangona ingozi ekhona njalo, kwaye kuphela ukuba ugqirha amisele yokwamkela isiyobisi elinzulu kakhulu.

analogs

Iipilisi ineempahla esebenzayo Indomethacin ziveliswa iinkampani ezininzi amazwe ekhaya, ezifana inkampani "Sopharma", "Ludwig Mekle" "Nycomed", "Farmahim", "Berlin Chemie Menarini," "Altfarm". Kuphela ngalinye ichiza igama layo lorhwebo, ukwakheka amabakala alo abangabancedani. Zonke oqondela Yayibubungqina efanayo ukusetyenziswa, iziphumo ebezingalindelekanga, Izimo.

Siyobisi ethandwa "Indomethacin Sofarma" (tablets). Iveliswe xa umthamo we-50 ne-100 mg yi "Sofarma" (Bulgaria). Libhekisela non-steroidal amachiza-ukudumba.

Nesinye isibini esingekho ngaphantsi analogue aziwayo - amayeza "Indomethacin 50 mg of Berlin-Chemie" yaye "Indomethacin 100 mg of Berlin-Chemie". Iveliswe ku iidosi ezimbini (50 no 100 mg) yinkampani Italian "Berlin-Chemie Menarini".

Xa Elungiselela "Indomethacin" (tablets) kufuneka analogue kunye nemveliso Russian. Ukuba ziyafumaneka kwiintlobo balawule ezahlukeneyo. ezi nabalingani eziphambili:

• "Indomethacin-Acre" Chemical-Pharmaceutical Plant JSC "Akrikhin";
• "Indomethacin-Altfarm", LLC "Altfarm";
• "Indomethacin-Biosynthesis", JSC "Biosynthesis";
• "Vero Indomethacin", OJSC "Veropharm".