Lwefibrinogen - nanjengokwesimo kwaye kwegazi

Xa isifundo kwenkqubo igazi ekunqandeni, le yesalkathisi uzimisele ngokuyimfuneko. Kubalulekile ukuba kwiimeko ezahlukeneyo. Phambi kokuba ukusebenza, ukulungiselela zokubeleka, izifo sentliziyo kunye yokukrala igazi isoloko ukucacisa lwefibrinogen. UNorma wayengekho okufanayo abadala kunye nabantwana. Kumabhinqa akhulelweyo, nelona qondo liphezulu yayo ephezulu kakhulu. Kodwa ukugxila kwimigangatho kamva kancinane. Okokuqala, makhe sithethe ngoko jikelele imele lwefibrinogen.

Ngokutsho kulwakhiwo yemizimba yethu, oko - protein. Libizwa ngokuba izinqumisi ngakumbi I. ebandakanyekileyo kwinqanaba lokugqibela igazi ekunqandeni, ezizezi - kukwenziwa ihlwili legazi. Xa lwefibrinogen yabantu abasempilweni yegazi ekhoyo kurhulumente iyapheliswa.

Kwimeko ukusebenza kwenkqubo coagulation kwinqanaba lwayo lokuqala phantsi amanyathelo kwezinye izinqumisi kwakhiwa thrombin.

Kwisigaba sesibini phantsi kwempembelelo lwefibrinogen kwamahlwili kunye thrombin lwanamathela aguqulwe fibrin ezingenakunyibilika, nto leyo isisiseko ihlwili legazi, a thrombus. Oku kubandakanya ukuyeka ukopha. Ngoko kuba intsingiselo ngokucacileyo ukuba umzimba ukuba lwefibrinogen. Ummiselo yale kweziyobisi umntu omdala onempilo ingqamana 2-4 g / l. Xa ezisanda kuzalwa, izinga mncinci - 1,25-3 g / l. Kodwa liphuma ngexesha ukhulelwe 6 g / l. Oku kuyaqondakala. Ngapha koko, umzimba umfazi ilungiselela ukuba umntwana wabo, yona isoloko ezinxulumene ne ukopha. Ngoko, kwenzeka, izinga lwefibrinogen egazini alufani bonke. ngayo iphezulu kakhulu kwabasetyhini abakhulelweyo.

"Ewe, kodwa ivela phi?" - eniyicelayo. Kubonakala ukuba le into ekunqandeni evela wesibindi iiseli kwenkqubo reticuloendothelial. Ngoko ke, xa izifo kwesibindi, ezifana hepatitis okanye ukuqina lwefibrinogen enzima wakhe norm - hayi ngaphantsi kwe-2 g / l, maxa wambi zancitshiswa amanani amancinane kakhulu. Oku kunokukhokelela iindidi ukopha, ukopha eluswini kunye ngenwebu yangaphakathi. Ukuthatha iziyobisi ezithile (androgens, steroid) Kwakhona ukunciphisa izinga layo. Kwezinye iimeko, kukho iimpazamo ezizalwa yemfundo factor I. Oku kuthiwa afibrinogenemia okanye hypofibrinogenemia.

Ukwehla ezibukhali lwefibrinogen elifana neli kwisigaba sesibini neyesithathu dessiminirovannogo intravascular coagulation syndrome. Le imeko enzima lwezidumbu, ngokufuthi ophela nge legazi Nanjengomvumbi ngenxa ukuyilwa iinqanawa ezincinane amahlwili fibrin saa. Wabo kangangokuba lwefibrinogen kabi emithini. fibrinolysis Acute, inkqubo leyo ehambisana kunye nokomelezwa wokupheliswa fibrin, nayo sikhatshwe ukuhla lwefibrinogen. Oku kunciphisa wegazi ezingapheliyo myeloid, kunye ukuswela vitamin B12 apha emzimbeni kunye S.

Kwezinye izifo, phezu koko, kukho i lwefibrinogen ukwanda. ISithethe ixabiso elikhulu coagulating into ilingana no-4 g / l. Kodwa rheumatism, izifo ezosulelayo, iinkqubo ukudumba, umhlaza, thrombosis kunye infarctions factor ndiya kuzilungelelanisa angandiswa ngokuphindwe 1.5-2.5. Lwefibrinogen ukwabizwa ngokuba kwisigaba protein etsolo, ekubeni ungeniselo lwayo lukhatshwa sisifo oyingozi arhabaxa. Inqanaba le protini belimele, ukusetyenziswa zokucwangcisa yomlomo estrogen emva kotyando.

Kukho ubungqina bokuba amanqanaba lwefibrinogen ephakamileyo ukuze kwandulela imbonakalo kwamalungu omzimba kunye isifo sentliziyo. ubudlelwane phakathi kwezi zifo kwaye umgangatho wayo zangaphambili ephakamileyo yafunyanwa kuphando.

Ukuze ukuqinisekisa inqanaba lwefibrinogen, Uze udlulele ungatyanga engenanto igazi emthanjeni. Igazi kuthathwa yaba tube uvavanyo kunye anticoagulant.