Epidermal necrolysis ityhefu: iimpawu, izinto, photo

izifo zobunewu dermatological ukuba ingaba ubomi emngciphekweni, musa zenzeka rhoqo kakhulu. Noko ke, bona. Enye yezi ithathwa ezinetyhefu epidermal necrolysis. Le ngezifo sisifo engaqhelekanga ulusu ezinokukhokelela ekufeni.

Yintoni zokugula?

Enetyhefu epidermal necrolysis - a ngezifo namachiza okanye nezidlo, nto leyo ebangela ukuba kwecala umaleko eliphezulu ulusu. Ke emva koko afe nomzimba ubethwa a ukunxila olomeleleyo. Ngaphandle konyango abafanelekayo abantu Inokwenzeka nokudumba kunye nokufa.

ukufa Bullous inguqu kwaye phantsi kuphela eluswini, kodwa ngenwebu yangaphakathi. Esi sifo zinzima kakhulu. Isibakala sokuba uqhankqalazo bangase yangaphakathi inwebu yangaphakathi, nto leyo ngokufuthi ekhokelela ukopha esiswini, ukusilela yokuphefumla, umsebenzi kunye nezinye ukunyhashwa eziphilayo.

Amaxesha amaninzi velisa ityhefu epidermal necrolysis emva ukusebenzisa iziyobisi ezithile. Noko ke, izizathu ukuze abanye. Ukuvela ikhondo esi sifo phantse akunakwenzeka ukuba ibone.

oonobangela

Unobangela oqhelekileyo izifo ukusetyenziswa kweentlobo ezithile iziyobisi:

• Sulfonamides.
• Macrolides 'Erythromycin. "
• amachiza penicillin.
• Anticonvulsant: "lamotrigine", "carbamazepine", "Phenobarbital".
• Quinolones "Trovafloxacin".
• Protivovspalitelnye amachiza nonsteroidal: "Indomethacin" "ibuprofen," "piroxicam".

Le izehlo lisezantsi kakhulu kwaye kunjalo 1 kuphela abantu abazizigidi 1 kunyaka ngamnye ngamnye. Amaxesha amaninzi kuchaphazela amabhinqa. Ubudala nalo kubalulekile, njengoko uninzi amatyala ngezifo elifana neli emva kweminyaka 55.

Ukongeza ekuthatheni amachiza ukuba necrolysis kokuhluma zosuleleke ngayo yi-HIV lwesikhumba.

Iimpawu ze kuphuhliso sifo

Epidermal necrolysis ityhefu kusenzeka ngokukhawuleza ngokwaneleyo. Kwimeko yokugula amajoni omzimba akakwazi ukubona kakuhle kwaye yokungenelela izinto ezingenabungozi, kule meko ichiza zonyango. An uxabane unamandla kakhulu.

Kulo mzekelo, amajoni omzimba ehlasela eluswini, kuba iqwalasela kubo umzimba amazwe. Ngaloo ummiselo nokubola kweziyi iphazamisekile. Isikhumba iqala ukuba nomzi ityhefu ezikhokelela ukunxila iyonke. Ukuba ayenzi uqale unyango, loo mntu uya kufa.

Species zalapha

Enetyhefu epidermal necrolysis (iimpawu zesifo, siye sele ngazo) ukuba zihlelwe ngolu hlobo lulandelayo:

1. Idiopathic. Oku kwenzeka ngokuzimeleyo, kwaye azinako ukusekwa ityala layo.
2. Zibangelwa impembelelo iziyobisi ezithile.
3. Ezivele phantsi kwempembelelo a usulelo lwesikhumba. Olu hlobo leengxaki banesifo kakhulu ebantwaneni. Kulo mzekelo, kungenzeka kukufa ngaphandle.
4. Kudityaniswe nezinye izifo.

Ezitshangubeni unako zabonwa kwiindawo ezinjalo: ezimpundwini, amagxa, esifubeni, emzimbeni umva, isifo ngomlomo.

symptomatology kwesifo

epidermal enetyhefu necrolysis (Lyell kaThixo syndrome) uqobo luphawulwa ezi mpawu zilandelayo:

• imeko Iyonke ukuhlukunyezwa umzimba esizibonakalisa ilahleko kudla, intloko ebuhlungu, ukunyusa iqondo Uhlobo Lokuqala. Ngokufuthi uphawu leengxaki inyuswe linxano.
• Ubuhlungu kuhlolwe kwi inwebu yangaphakathi. Noko ke, ubuzaza yabo banda kakhulu. Ngokomzekelo, xa zisitya isigulane lusiva intlungu xa ukuginya.
• Kukuvela amabala abomvu, irhashalala kunye namadyungudyungu kwi nesikhumba ngenwebu yangaphakathi. Kwiimeko ezininzi oku kuchaphazela malunga ne-30% aloo mzimba mnye, nangona oku kuba inkulu kakhulu.
• Exfoliation ye sangaphandle. Kulo mzekelo, isikhumba uqalisa ukuyishwabanisa kwanaxa touch buthathaka. Ukuba indawo uchaphazelekayo womGaqo ulusu ukususa izakuvela ngaphantsi inxeba elophayo.
• insufficiency kwezintso.
• inkqubo Infectious. Inyaniso ukuba ulusu akakwazi ukusebenza kakuhle kwaye abakhusele abantu sesichengeni ngamagciwane. Imeko kungabangela nokudumba.
• Kumanqanaba yamva sifo angabukela emzimbeni, tachycardia kunye hypotension.
• Ubuhlungu imisipha.
• Fever kunye khohlo.
• Anorexia.
• Isicaphucaphu kunye nokugabha.

Thatha ingqalelo ukuba izilonda mucosal kwenzeka ngokukhawuleza gangqa eluswini sifo. Emva koko wabonwa kamva naye kakuhle kakhulu ukuba sikwinqanaba lokuqala ityhefu epidermal necrolysis, ifoto apho akusingisi kokhona ontliziyo ithambileyo, buqapheleke kancinane.

uxilongo Iimpawu

Ukuba ngaba uye wakrokrela ayingozi epidermal necrolysis, kufuneka udibane nogqirha wakho ngoko nangoko. Umele enze isifo umahluko kunye ngokucokisekileyo kakhulu, nto leyo iquka:

1. izikhalazo nitrogen ixhoba. Kucelwa nithathele ingqalelo zonke irhashalala, ukushukumisa iintlungu.
2. Ukuqokelela imbali nomonde. Oko kukuthi, ugqirha kufuneka ufumanise ukuba ingaba ke uxabana ukuba negalelo kuphuhliso sokungamelani ezintsonkothileyo. Uyacetyiswa ukuba ufumanise ukuba iingxaki ezifanayo emizalwaneni yesigulana.
3. uviwo lwangaphandle isigulane. Kulo mzekelo, wesikhumba utsalela ingqalelo ibala lolusu, ubukho izilonda namadyungudyungu kwi inwebu yangaphakathi. Isiguli esisabela ngayo kwindawo yabo nto kakhulu ngokwaneleyo.
4. Uhlalutyo igazi iyonke. Uya kunika ithuba lokuba ukujonga amanqanaba nokuba eziphakamileyo iiseli ezimhlophe zegazi, ngaba kukho iiseli igazi ubuntwana, ekukhawuleziseni erythrocyte neentlenge. Ukuba aba parameters ukuya ngaphaya kwemida eziqhelekileyo, imeko ibonisa ubukho komtshiso oko.
5. Uhlalutyo ezinto igazi. Ukuba ngenxa kukho inqanaba ephakamileyo yibilirubin incinane kakhulu, okanye isixa protein, isigulane babe neengxaki umsebenzi zezintso.
6. Urinalysis. Olu phando kwakhona ziyafuneka ukumisela umsebenzi zezintso. Ukuba kukho igazi, ngoko, le nto ehlabathini lonke yokuchama.
7. Umlinganiselo umsebenzi wentliziyo, parameters uxinzelelo lwegazi.

Uxilongo kubalulekile ukuba umahluko phakathi ezinetyhefu epidermal necrolysis nezinye izifo: pemphigus, ifiva nebomvu, erythema, impetigo bullous, planus ulele.

Iimpawu zonyango

Yandlalwa yi sifo kufuneka ziphathwe. Kungenjalo, isiguli ulinde nokudumba kunye nokufa. Ukuba isigulana ndandikho mpawu zingasentla, ngoko ke kufuneka zisiwe ngokukhawuleza xa iimeko esibhedlele. Ukuba kunzima esi sifo, ixhoba yafakwa labagula kakhulu, apho abasebenzi bezonyango kumnika ngenkathalo olwaneleyo.

I Chamber, leyo uyagula, kufuneka engenazintsholongwane, nto leyo eza kuphelisa ithuba wokujoyina nezinye izifo. Pathology Unyango ibandakanya ukususwa ezenza ukuba kwadala sifo.

Ke ukuba unyango ngamachiza, ngoko kuya kubakho ukunceda corticosteroids kunye antihistamines. Ukongeza, kufuneka kulungiselela kunyango ukumnika. Antibiotics zingasetyenziswa kuphela xa kuthe ogulayo ukulawula usulelo eziziisekondari.

Enetyhefu epidermal necrolysis (oko kukuthi, sele ukwazi) kufuneka kwakhona ziphathwe ngoncedo imithombo yendawo ukunceda ukubuyisela yesiqhelo ulusu ngokutsha: iintlungu (ntlungu), namafutha aqholiweyo, ebulala.

Ukongeza, kuya kufuneka ukuba balandele ngqo imigaqo unyango:

1. Kufuneka kube lula ngokukhawuleza gca evela emzimbeni ichiza sithathwa ngaphambili. Lisebenzisa enemas.
2. Kunqweneleka ukuba uthathe iziyobisi, igalelo nokubuyiselwa eqhelekileyo ukutya namanzi-ityuwa, ezifana "Regidron".
3. Ugqirha uyakukumisela amayeza sokukhuselwa kwesibindi, ingakumbi "Gepabene".
4. Ukwamkela agents zokunciphisa ekunqandeni igazi.

Ziintoni ezinobuzaza xa kwenzeka?

Ukuba ngaba une-ityhefu epidermal necrolysis, ezinobuzaza ukuze ziquka:

• Ukuveliswa usulelo yintsholongwane.
• emzimbeni ezimandundu, nto leyo ibangele ukufa yesigulane.
• Ukulahlekelwa isixa esikhulu yesikhumba. Ukuba umntu uphelelwa ngaphezu kwesiqingatha sangaphandle, it mela ukufa ethile.
• Omiswe of eluswini, ukuvela iziva kuye, tshintsha phakathi nombala.
• ukukhukuliseka Chronic ye inwebu yangaphakathi.

Outlook

Ukuba unyango leengxaki zange kwaqala ngo kwexesha, izinga lokufa ukufikelela 70%. Ukulahlekelwa yinxalenye ebalulekileyo ulusu uya kwenza umguli sifo kakhulu izifo.

Ngexesha unyango liqale akayi kuphela kunceda kukuphelisa esi sifo, kodwa kuya kunika ithuba lokuba siphephe iingxaki ezoyikekayo ezifana ezifana yophela ngaphakathi, umonakalo kwinkqubo genitourinary, ukungakwazi ukuthatha ukutya, ukusilela kwezintso nesibindi.

Kufuneka kuqatshelwe ukuba abantwana bayasweleka ngenxa yesi sifo ngaphantsi kakhulu abadala. Ukuba isigulane eqinisa eyimbalasane nyaka-60, oko sase- yedanisayo. Noko ke, unyango olufanelekileyo unako ukuphucula imeko yakhe.

Prevention zokugula

Elinye igama le ngezifo njengoko ezinetyhefu epidermal necrolysis - Lyell engqondweni. Iifoto esi sifo kubhetele ukuba ukujonga abantu msinya. Esi ngezifo oluxandileyo, zinokuphetshwa ukuba ulandele amanyathelo othintelo:

• Imithi kufuneka zithathwe kuphela xa amiselwe ngugqirha.
• Yingcali kufuneka azi ukuba kukho negazi lakho.
• Enoba ngezifo usenokuba, kufuneka uthathe iziyobisi ngaphezu kwe-7 ngaxeshanye.
• Musa self-staphylococcal kunye nezifo zolusu arhabaxa.
• Kuphephe nokwayamana nangaliphi esahlala ezinokubangela komzimba.

Ke ukuba unyango, ngoko konke oko kuxhomekeke iimpawu eziphilayo nomnqweno lomguli ukujongana ukuhlukunyezwa. Hlala uphilile!