Hyperplasia - yintoni na le nto? hyperplasia Glandular endometrial. hyperplasia Lobular le endometrium

Hyperplasia - isimo kukwanda kwenani iseli a zomzimba okanye ilungu (ngaphandle emzimbeni ithumba). Isiphumo kuphuhliso kwesi sifo ithumba okanye ukwanda iphawulwe nobukhulu bomzimba.

Liphuhlisa hyperplasia kamva iintlobo ngeentlobo iimpembelelo ezichaphazela andise iiseli ezakhayo. Ngenxa yoko, ukukhala uphuhliso zizinto antigenic izinto oncogenic, abanyuseli ukukhula okanye ilahleko izihlunu, ngenxa yaso nasiphi na isizathu, iziko okanye inxalenye kwithishyu. hyperplasia period - a wazithi ngexesha lokukhulelwa le epithelium mammary, kubonisa hyperplasia glandular phambi okanye ngexesha esexesheni, nezinye ezifanayo.

Ngokomzekelo, hyperplasia, iimeko oluqhubekayo lwezidumbu, ekunokuthiwa ukunyuka isakhiwo kwizigulane kunye iintlobo ezithile igazi inyama myeloid. Ukongeza, iinkqubo hyperplastic nga kwenzeka kwiindawo zeethishu nkovu lymphoreticular, njengoko omzimba kwi udakada, kwimeko kwezifo yendalo ezosulelayo.

A iintlobo

Xa amayeza, kukho iindidi ezininzi ezisisiseko:

1. hyperplasia period. kwenzeka ukukhula lolwabo, nto leyo esebenza okanye okwethutyana. Umzekelo, hyperplasia of mammary kwamadlala ngexesha zisanyisa okanye yokukhulelwa.
2. hyperplasia yezifo. Ngenxa eziliqela ukunisa zenzeka ukukhula kwithishyu.

Ukongeza, esi sifo kuba focal, kwentamo kunye polypous:

1. Xa kukho indlela ecacileyo yenkqubo kwasendaweni bamalungelo ezesini ngohlobo izigaba.
2. In kwentamo hyperplasia bobuso ochaphazelekayo umaleko.
3. Kuba uhlobo polypous luphawulwa ukwandiswa ngokungalinganiyo kokuxhuma. Kulo mzekelo, hyperplasia ukukhala uphuhliso emfundo onganeno kunye cysts.

hyperplasia kwentamo le ingaba lengqula

Esi sifo kwenzeka yokusabela xa zembuyekezo kwi lengqula Iodine. Igama elithi "kuyenye" oko kuthetha ukuba ngezifo kuchaphazela umzimba lonke: kukunyuka ubukhulu bayo ngenxa yokuzala kweeseli prostate ukwenzela ukugcina secretion of hormone ezikhuthaza ukutya, ekukhuthazeni ukufunxeka inqanaba lamandla oxygen axhasayo.

Thyroid iodine ukuba bagcine umsebenzi wayo hormone. Ukunqongophala okanye ukungabikho ayodini ikhuthaza kunyebeleziso iiseli umhlaza kwaye emva koko kunokuphumela kwekhono.

hyperplasia adrenal

Esi sifo ngokukhukhumala kwentamo okanye nodular. Oko kukhatshwa ngokuqhubeka zomzimba adrenal kwimeko yamathumba pineal kunye Cushing engqondweni. Xa abadala, olu hlobo hyperplasia, ingakumbi ekhohlo-sasekhohlo, kunye isifundo ultrasound kunzima kakhulu ukuqaphela uhlala ndaba zokufunda yi-MRI ne CT.

Ngamanye amaxesha kuyenye hyperplasia adrenal lukhatshwa zokunyanzelisa banda ngexesha kugcinwe amadlala imbonakalo eqhelekileyo - ngohlobo kwezakhiwo hypoechoic, engqongwe izicwili okunamafutha. Kwimeko hyperplasia nodular kwi "unxantathu amanqatha" kubonakala ngeenxa zonke, ukubunjwa eyohlobo olulodwa hypoechoic. Kunzima ukwahlula ukusuka adenoma kumfanekiso ultrasound.

Prostate - hyperplasia ebubonisayo prostatic

Malunga ne-85% amadoda amadala ngaphezu kweminyaka engama-50 isengumba sifo. Ebubonisayo hyperplasia prostatic luphawulwa ukuyilwa maqhuqhuva yesinye ezimbalwa ezincinane (okanye omnye) apho isasazeka ngokuthe ngcembe baqale cofa kwi urethra, nto leyo ebangela kamva ubunzima ukuchama.

Isifo akubangi Ukudlulela, ukuba into iyayahlula i umhlaza yakhe yesinye, ngoko ke kuthiwa hyperplasia ebubonisayo prostatic. Kulo mzekelo, akukho oonobangela ecacileyo kwaye idla ngokwenzeka ukuya exesheni eyindoda.

wesizalo endometrium

Hyperplasia - ukwanda nabungozi Ebubanzini nomthamo ingaphakathi zesibeleko. Inokwenzeka ngenxa ezizalayo njengoko glandular kunye nezinye iiseli zeethishu. Isifo kunokukhokelela ukuphazamiseka umsebenzi esebenza endometrium (iingxaki kumitha, menses kakuhle).

Phantsi kweemeko eziqhelekileyo, le endometrium sikhula phantsi sisenzo estrogen kwixesha kumjikelo wokuqala, phantsi kwempembelelo dlala ngethuba wesibini zomjikelo ovalelweyo. Xa ngezifo lokukhula endometrial na okutyekisayo, ikwazi lokubamba kokubini esingxotyeni ewonke kunye iindawo ngamnye (lobular hyperplasia).

Imihlobo hyperplasia endometrial

Ngokutsho ngakumbi ubukho bezinto izinto ezithile kule endometrium ekhulayo akhululwe:

1. hyperplasia Glandular. glands Endometrial ukukhula kwemfuneko.
2. hyperplasia Polypoid. Ukuya ukukhula zineengxaki le endometrium, leyo glandular, glandular-ezinezikhondo ezinezikhondo endalweni. Olu hlobo hyperplasia akufane uba yingozi, kodwa unako ukukhonza njengesiseko sokuphuhlisa izifo yamanina.
3. hyperplasia Adenomatous ne phambi iiseli Nedlac, premalignant. Kule ukonakala kwindawo hyperplasia umhlaza olu hlobo ukuze ibe ngu-10%.
4. hyperplasia esinganyangekiyo glandular. cysts ndlala kwaye akhule ngayo efanayo.

oonobangela

Ukuza kuthi ga ngoku, esona sizathu sokuba esi sifo kwakuwo yokungabikho isalamane kumanqanaba dlala estrogen nokomzimba. Loo imeko kunokubangela:

1. yobudala yeThutyana waphula nethe hormone hormone.
2. ukutyeba yabafazi.
3. Polycystic Isiyillo Syndrome.
4. kwabadala.
5. Ukwamkela amalungiselelo eziqulathe estrogen, ngaphandle kokufumana dlala.

Amaxesha amaninzi, hyperplasia endometrial (izimvo ezivela kwiingcali ukuqinisekisa oku) libonakala abasetyhini phambi exesheni ekuhlanganisweni kweentombi nulliparous.

Comorbidities, ukunyusa yokubonisa hyperplasia, ingqalelo ingxaki esinobubovu adrenal kunye nencum, isifo lengqula, iswekile sinwenwa kweendidi zombini, kwakunye noxinzelelo lwegazi. Ngu kuphuhliso hyperplasia nabo ukuba imiba efana:

1. Ufuzo izifo zangasese.
2. Adenominoz.
3. fibroids wesizalo.
4. Isisu kunye curettage.
5. iinkqubo arhabaxa esini.

Izizathu uphuhliso kunye neentlobo hyperplasia glandular endometrial

Main ibangela hyperplasia glandular:

1. Anovulation.
2. Amavila.
3. Ukubakho cysts follicular.
4. Kwabadala.

Kananjalo umngcipheko yozingiso follicle syndrome, glycemia kunye iseli granulosa nangezilonda.

Yokunqongophala konyango kunye isifo ilibasiza esi sifo, naxa oko nemiphumo eyingozi, njengoko uphuhliso umhlaza endometrial. Isikakhulu olusemngciphekweni nabafazi abaphethwe ademonatoznoy hyperplasia Nedlac nabafazi kwixesha emva ukuya exesheni. Kuyinto focal kunye hyperplasia ehlasela - uhlobo precancerous kwesi sifo.

Ezinye iintlobo hyperplasia endometrial zithathwa ukusasazeka olumandla epithelium glandular, amadlala esinganyangekiyo inimba kunye hyperplasia glandular-esinganyangekiyo.

iimpawu

Kwiimeko ezininzi, hyperplasia kwamadlala kwenzeka ngaphandle iimpawu ezahlukahlukeneyo clinical. Kule ezibonisa eziqhelekileyo zithathwa ukopha zesibeleko kukuba iveza okubangelwa yezitenxo exesheni (menses ukulibaziseka). Le ukopha kunokuba zombini lweenkcukacha kunye elide, kunye nelahleko igazi - enzima okanye ukumodareyitha. Ngenxa yoko, ukuphuhlisa iimpawu zobuthathaka begazi lakho: ukulahlekelwa wokutya, ukudinwa, buthathaka.

Phakathi iiphiriyodi kungabonwa zokubona. Lidla ngokufuthi abafazi ngenxa amatyala anovulation ukungachumi. Yiloo nto kanye isizathu ubudlolo i uhambo ugqirha emva koko ukuhlola isifo. Phakathi iimpawu nako makuqatshelwe iintlungu kwindawo esiswini asezantsi.

Uxilongo hyperplasia glandular nga kwenziwa dilatation kunye curettage, nto leyo yenzelwa ngokukhawuleza phambi kokuba sexesheni. Kaninzi isetyenziswa lokufunyaniswa ultrasound, kunye hysteroscopy.

hyperplasia lobular

hyperplasia Lobular (iingcali ncomo zingqinele oku) Wayemsongela umhlaza zingachumi ngokwaneleyo. Okwanamhlanje sho okanye nazimpawu lunokukhangela izinto sifo kuphela ngethuba ultrasound okanye uviwo yamanina.

hyperplasia Lobular ngokuqhelekileyo andise kamva enokuphazamisa hormone, emva ukutshintshwa izifo somatic kunye izisu okanye kwimvelaphi hyperplasia lohlobo glandular.

hyperplasia Lobular of zesibeleko epithelium banesifo ngokusekelwe ezi mpawu zilandelayo:

• ukopha emva ukumisa sexesheni;
• acyclic okanye yezitenxo elibujikele exesheni.

Unyango lwesi sifo ngeendlela ezimbini eziphambili:

1. indlela lwezonyango - ngoncedo kwamachiza ezizodwa, kuquka nemvelo hormone.
2. Utyando okanye operative indlela - ekrwela lweHo- zesibeleko.

Uxilongo lwe hyperplasia endometrial

Isiseko uxilongo kwesi sifo uviwo eyenziwe ugqirha, kuba uphando nezixhobo kunye elabhoratri.

Iindlela eziphambili sifo ziquka:

1. Ultrasound zoviwo wesibeleko kunye ezihlobene probe lobufazi.
2. Hysteroscopy kunye nemiboniso biopsy lokubhalela uviwo histological.
3. Zokuxilonga sisusa Faka zesibeleko.
4. Ukuba kuyimfuneko, ekucaciseni uhlobo hyperplasia zabanjwa mgomo biopsy.

Enye zophando ezibalulekileyo yemigaqo inkcazelo bamanqanaba-serum sex hormone kunye lengqula, kunye namadlala adrenal.

Kubalulekile ukukhumbula ukuba naluphi na uhlobo hyperplasia ifuna ukuxilongwa uze uchonge ezibangela oyinyaniso, nto leyo yakhokelela ekwandeni kwithishyu.

unyango

Ukuba unesifo hyperplasia, unyango wenziwa ngoko nangoko. Le ndlela kukhethiwe isekelwe phezu iimpawu zesi sifo yaye ubudala isigulane.

Eyona ndlela isebenzayo - curettage zokuxilonga okanye inkqubo ukususwa hysteroscopic kwi endometrium kwentamo.

Ukuba inkqubo unyango multi-character, kuqala kwiinto zonke, enze yonxunguphalo okanye kokuphalwa ekunokukhethwa kulo. Asebenzisa a ngobuwena kuqala xa anemizatsii okanye ukopha.

Zakuba zifunyenwe iziphumo histology, ingcali unganika unyango zilandelayo:

1. Eneminyaka engama-35 iminyaka prescribers bachasene of gonadotropin.
2. IUD "Mirena" kunye progestins.
3. amachiza progestin ( "Djufaston", "Utrozhestan") sabelwe khona ixesha yesibini komjikelo.
4. Ukulungiselela injongo stop non-yokusebenza ukopha amantombazana eselula, bavumelekile ukuba zisetyenziswe ngeedosi ngokungenamkhethe enkulu lokucwangcisa ngomlomo.
5. Kolimo izivimbela ( "regulon" "Yaryna" "Janine") wabelwa ukuya kwiinyanga ezi-6 kunye beesekethe reception yesiqhelo.

Amalungiselelo zikhankanywe ngasentla, ukwenza isiphumo esifanayo ukuya exesheni, kodwa ingathityazwa.

Emva sisusa ngenxa iinyanga ezintandathu iliso, kwaye xa kukho ukwenzeka kweefom hyperplasia adenomatous, nto ibonisa ukususwa isibeleko. Xa ezinye iintlobo relapsing nokungasebenzi amanye amayeza avelise intshabalalo ngumntu lo endometrium (ablation).

Abane kunye nobunzima

Obona bunzima eziyingozi hyperplasia endometrial - Nguwuphi wayo umhlaza wesibeleko. Noko ke, ukopha akukho yingozi ngaphantsi kunye sisifo kunye nophuhliso ubudlolo kwakunye nezinye.

Kwiimeko ezininzi, ukuba abantu abane entle: ngenxa yeziyobisi kutyando prima iinyanga 6-12 akakwazi kunyanga ngokupheleleyo esi sifo.

ukuvimbela

Le milinganiselo ibalulekileyo yothintelo lwe hyperplasia endometrial - kukuthintela iimeko ezibangela, kukho umlo asebenzayo ngokuchasene unyango abatyebe yaye ngoko nangoko ukuphazamiseka ukuba sexesheni. Kwakhona kubalulekile kakhulu ngexesha loviwo yamanina yabafazi.

Ngamanye amaxesha amantombazana aselula specialist ingenza isindululo malunga nokuthintela amachiza hormone zokunciphisa umngcipheko hyperplasia endometrial kunye nomhlaza. Nawuphi na umfazi kufuneka bazi ukuba xa kuthe zesibeleko ukopha kufuneka kwaoko andibhekisanga yincutshe. Khumbula ukuba unyango ngexesha ugqirha iza kunceda elizayo siphephe ezininzi iingxaki.