Ezingabonakaliyo iliso yesiqhelo Blashko umgca emzimbeni womntu

Imperceptible ukuya iipateni ngeliso lenyama emzimbeni womntu kwenzeka phantsi kwempembelelo yeemeko zemveli kunye zithe zadala ezimbi. Ikhethwa yi ngezifo nemigca Blashko. Melanogenesis wabonakalisa hypopigmentation, ubalisa iqela kwezifo dermatoses. umdla Iyabonakala ebubonisayo kwinzululwazi. Qonda Umgaqo imbonakalo ithumba, sinako ukuthintela imbonakalo wolusu.

Imbali isifundo kwezifo zezikhumba

ngumphandi German iingxaki dermatological wafumana Blashko umgca ngo-1901. Bamele umzekelo nombala, efanayo isakhiwo kuzo zonke izigulane. Esi sifo yathiywa emva igama ingcali yenzululwazi, ogama lakhe Alfred.

ubudlelwane wesikhumba esekwe lubandakanywe leengxaki X-zofuzo. On utshintsho yesikhumba imperceptible qete ingqalelo yabo yesiqhelo. Ngenxa yokufuduka umbhodamo malanoblastov lokusekwa ipateni mmandla ebonakalayo. Isimo kweeseli mutated lixhomekeke breakdowns luvo emzimbeni wakhe. Noko ke, iingxaki dermatological inokufumaneka ilifa naso esi sifo.

Izizathu eziphambili ezibangela ezinxaxhileyo kwesikhumba kwabantu

Chonga zinto zilandelayo Education Blashko umgca phezu umzimba:

• Chimerism - elikholisa ukubizwa ngokuba imeko xa umntu uphaphileyo iindidi ezimbini DNA. Iseti ezahlukeneyo yemfuza kubangela ukuyilwa nombala emzimbeni. Ezi ziphumo zibonisa ombulo kunye beentlanga ezimbini ezahlukeneyo. Oonobangela yesikhumba ngezifo uba ngxubevange iqanda aqhamileyo kwibakala zokuqala zokukhulelwa.
• uxinzelelo Human emzimbeni - ipateni umbhodamo yenziwe.
• Genetics - utshintsho DNA yomntu. Isizathu sokuba imbonakalo leengxaki naso iba nevi: depigmented, ulwehlo, sebaceous, yomgama verrucous arhabaxa.
• Yemfuza DNA ukuxuba ngexesha embryogenesis - izazinzulu enyusiweyo isakhiwo izicwili yabantu: kwenye endlwaneni iseti yemfuza uyabonakala. Nangona imvelaphi yokugqibela livela elilodwa enye.

Indlela emi ngayo ukubonakala dermatosis

Akukho nzima ukuba akazi elithi "Blashko umgca" - yintoni loo mgca? iingxaki ezinjalo afunyanwa rhoqo kwi kubelekwa, mabangabi ngaphezu kwe-2% yayo abakwazi kubuphepha inkangeleko ezimbi. Ubume be-DNA ekuqaleni iqulethe isifo ulwazi. kuvela iimpawu zangaphandle ngenxa yomzimba ezinxaxhileyo hormone.

Blashko line luphawulwa iiseli ezintathu emzimbeni, ngumthombo esi sifo:

• keratinocytes Epidermal - ngezifo ezifunyenwe sivame ngenxa chimerism.
• Ebala - ise kwiingcamba asezantsi sangaphandle.
• Iprofayili iiseli ebala umda - kukhokelela utshintsho umbala eluswini, acandacanda inwebu ongaphantsi ibe umaleko ephezulu dermis. Le meko ke ambona uhlobo wendalo ekumisweni wolusu.

iimpawu zangaphandle

Uncwadi yonyango inika inkcazelo malunga imigca Blashko: ukuba kukho isifo izicwili zomntu, esizibonakalisa kwimeko lokungaphumeleli emzimbeni ubomi. Ulwakhiwo ipateni ezingabonakaliyo xa inxalenye umva lufana umbala izilwanyana: Jwarha okanye ingwe. Kokuba kuqwalaselwe yi yelanga.

Ibala lolusu lwabantu kuxhomekeke osisiqu esinye melanin. It senziwa sangaphandle kwizihlunu umaleko carcinomas, iquka melanocytes. Ezinxaxhileyo kule nkqubo melanogenesis kukhokelela ukutshintsha umbala abangaboni perceptible:

• Hyperpigmentation - ipateni umbhodamo amabala ezimnyama kakhulu eluswini, ahluka ngokucacileyo ukususela izigqubuthelo ezisisiseko umthunzi.
• Hypopigmentation - ukulahlekelwa umbala kweeseli zolusu, ngenxa iindawo ezimhlophe. ngezifo Onge waphawula hayi ngaphezulu kwe-1% of ezisanda kuzalwa.

Ebonakalisa yangaphandle ipateni sifo kuba V-ezimilise, ngokohlobo curls okanye imigca siziinduli. Amaxesha amaninzi kwakheka kula amalungu omzimba:

• back;
• emacaleni;
• amagxa;
• intloko.

ekuxilongweni ingxaki

Line sokuzoba Blashko oqaphelekayo xa umntu okufakwe nokukhanya yelanga, kodwa ngenxa yomphefumlo kunqabile idlula uviwo olo. Ukuze ukufunda imo yomzimba eqala sele zikumanqanaba okuqhubekayo sifo. Xa ezisanda kuzalwa, amatshatshazi of hypopigmentation emzimbeni kunzima ukubona. Umntwana ofumana utshintsho mpela malunga ulusu kwiminyaka embalwa.

Kwi imeko iiseli bachaphazeleka iseti zofuzo. Ukuba eyahlukileyo kakhulu kumacandelo ezikufutshane ulusu, zokwahluka iqatshelwe amalaphu imibala. Ngoko hypopigmentation zingavela le miqathango ilandelayo:

• amabala umbhodamo - unomdla kwisayensi ngenxa izakhiwo olungalinganiyo. Lo mfanekiso ubonisa iimilo bayiqaphela ngohlobo bands, iiseli wechess.
• Yenzelwe - babonisa kwindawo enye kwindawo ethile.
• Ngokubanzi - usenokuphelekwa izifo ngamalungu zangaphakathi.

Kutheni kufuneka ukufunda imizobo apha esikhumbeni?

Amagqirha asebenzise kohlalutyo yokwakheka izicwili kwi iingxaki ezibonakalayo apha esikhumbeni. Apha, kuvezwa iphambili umgca Blashko, esi sifo uphando ngenxa uxilongo oluchanekileyo. Oku kubaluleke xa zilandelayo iingxaki dermatological:

• chimerism;
• mosaicism;
• zoster;
• nevus;
• wolusu.

zibalulekile, ukwakheka kwezinto ezinzima kuphela kwicala lophando, ngokuba engumshumayeli, azihlole akakafiki kungakhokelela kwizigqibo ezithile malunga nesifo. Izazinzulu oceba ukuze atyhile injongo iipateni emzimbeni womntu. Mhlawumbi ukufunyanwa iza kunceda ekupheliseni iziphumo sisifo solusu esinqabileyo.