Ukususwa - yintoni na le nto? iimpawu

Kuye kudala babecinga ukuba bume isisu, engenazintsholongwane kakhulu kuyo yokuhlala microflora. Esiswini, kunye nesiqulatho sayo zangaphakathi - asidi, okanye nje akazange kusinda eyodwa. Efumanise Helicobacter pylori kwisiqwenga zesisu iye yaguqula ingcamango uhlobo kwezifo emathunjini: gastritis, duodenitis, izilonda esiswini kunye nezilonda duodenal, umhlaza zesisu kunye nonyango lwabo. Kweli nqaku siza kuxubusha ngayo yonke into ngokuphelisa. Kuyinto indlela ethile unyango eye zithandwa kakhulu kwiminyaka yakutshanje.

Trip kwimbali Helicobacter pylori

Enyanisweni, igciwane yabhaqwa ixesha elide yaye hayi kanye. Ngokuba lixesha lokuqala oku kuye kwenzeka ekupheleni kwenkulungwane lokugqibela. Kwaba 1886. Jagiellonian University Professor V. Yavorsky ukubona iibhaktheriya imilo luphawu saya kwi izinto esiswini. Wayinika igama igciwane Vibrio rugula, waza wacebisa ukuba zidlala indima ekuphuhliseni kwezifo esiswini.

Noko ke, ingqalelo ngenxa akubanga umsebenzi Yavorsky ekuhlaleni zonyango. Kwiminyaka esixhenxe kamva, i-nzulu Italian D. Bidzodzero wazoba iintsholongwane kususela wokugaya le nja. Le elandelayo, owathi ubukho iintsholongwane iiseli esiswini evela kwizigulane ezisetyenziswa okwenziwa sisilonda sikabhobhosi kwaba uNjingalwazi Morozov eMoscow. Kwaba sele ekupheleni 70s zenkulungwane lokugqibela.

Eminye imizamo ukuchaza ithile, hlela, ukuze bakhule elabhoratri sihlolisise igciwane engaziwa sele kuqhutywa ngo-1979 no-1981 Australia Marshall kunye Warren. Baza baphumelela. Marshall ebibanjwe amava ngempumelelo self-ukusulelwa Helicobacter pylori kunye ukuphiliswa gastritis helicobacter ezifunyenwe ikhosi kwiveki ezimbini-zonyango with "metronidazole" kunye neetyuwa bismuth.

Le ndlela yenza isiseko ekutshabalaliseni namhlanje Helicobacter pylori. A abahloli nesibindi ngo-2005 wafumana ibhaso le-Nobel in Medicine.

Igama Helicobacter pylori ephilayo ngo-1989, kwakunye inkcazelo epheleleyo kunye yokuhlela. Ukonakala bacterium yokuhlala ukhethe "sango 'esiswini (" pylori "- ukusuka Greek" sango ") yosulela zonke iindawo duodenum kunye nesisu. Xa ipesenti ebonakalayo zonke gastritis, duodenitis, izilonda emathunjini kunye nezilonda duodenal de umhlaza wabo unetyala le silwanyana.

Ingozi yosulelo kunye Helicobacter pylori?

Helicobacter pylori, ohleli kwisiqwenga zesisu umntu okanye isilwanyana ukuba pores uziphatha malunga. Ngelo ukungaphumeleli incinane amajoni omzimba okanye iziphumo ezongezelekayo nokungondleki okanye imikhwa mpilweni igciwane isebenze uba ndlongondlongo. Yintoni kuyingozi? Siphila inwebu kwiinwebu izibilini - esiswini kunye duodenum - yayintsholongwane eyosulela silwanyana isenzo kuyo.

Iqala landa ukukhululwa iimfihlakalo, nto leyo echaphazela kakubi ngayo inyama zesisu. Yangaphakathi kubo uba evakalala, baphuke, kukho iindawo ebushushwini babo kakhulu lokusekwa izilonda. gastritis okubangelwa silwanyana yayintsholongwane eyosulela Helicobacter iqela pylori, ngokungafaniyo gastritis ngoomatshini eqhelekileyo, kodwa efanele ukuzinyanga iindlela eziqhelekileyo.

Helicobacter pylori lingena zonke ingxenye yaso kwithishyu, ngokwenjenjalo benge- antibiotics uninzi (elwa iyahlozinga kuzo iasidi). Loo vandalnye izenzo zakhe kubangela iinkqubo ezingenakuguqulwa kwi isifo, umzekelo, imeko precancerous, yaye, ngqo, uphuhliso Oncology. Ukuze uphephe oku, sebenzisa kwanokulwa Helicobacter.

Uxilongo lwe Helicobacter pylori kwisiqwenga zesisu

Ukuba isigulane ikhalazela of isicaphucaphu kunye ukungacoleki kokutya, heartburn, iintlungu, iingxaki esitulweni, abe nazo kabuhlungu kule ngingqi epigastric - isalathiso ngqo ukuba zihlolelwe ubukho kumzimba Helicobacter pylori. Cazulula rent zezi:

• igazi, uhlalutyo jikelele izoba, kuquka ubukho H. pylori;
• Uhlalutyo kweenyawo ubukho inkunkuma iintsholongwane;
• test umoya isekelwe ukumiselwa ammonia yoxinaniso ingumphunga;
• Uhlalutyo cytologic.

Indlela inokuthenjwa zokufumanis isifo yinto biopsy umcu le isifo esiswini kunye nezilonda duodenal. Eli laphu sithathwa uhlalutyo yi endoscopy.

Iimpawu wokuqeda

Njengoko sele kukhankanyiwe ngentla apha, ukupheliswa - yindlela ukujongana igciwane esiswini.

Ukususwa okwenziwa abagulayo ezimbi ezifana:

• Iimpawu isilonda esiswini kunye duodenum;
• post status resection (utyando ukuze ususe umhlaza);
• ithi precancerous ngemizimba zeethishu yoma;
• lymphoma.

Olusemngciphekweni abantu izalamane ubunzima zomhlaza. Kunconywa therapy yokuphelisa kwaye izigulane kunye nesifo reflux gastroesophageal kunye ukuqunjelwa esebenza.

iindlela wokuqeda

Ukususwa - ke intshabalalo, yokuphelisa (ngokuphelisa IsiNgesi.). Eli nyathelo, eyenzelwe kutshabalalisa usulelo kunye Helicobacter pylori phecana zesisu. Indlela unyango kubonisiwe izigulane isilonda kakhulu esiswini okanye isilonda duodenal. kubume bayo siyifumana kwikhosi lokuthathwa amayeza ngokomfuziselo ethile.

Phambi kokuba kuqale kwekhosi lwenziwa ukuqhubela phambili mucosal esiswini umcu ubukho iiseli amabi.

ekutshabalaliseni Helicobacter pylori na iintlobo ezininzi:

• mono, apho kufanelekileyo xa unyango enye kuphela kuthetha abafumana, ngokuqhelekileyo imithi esekelwe ityuwa bismuth, okanye isibulala-zintsholongwane;
• Duo, unyango mbini (vismutosoderzhaschee kweziyobisi kunye olwa);
• triplet, njengokuba igama lixela, le unyango kunye amachiza amathathu (bismuth, i zintsholongwane kunye neqela ummeli imidazole);
• kvadriplet, yakha ezine, apho kukho triplet esimbaxa wongeze PPI therapy (blocker of zehydrochloric acid).

IMono-wokuqeda - oku phantse asisetyenziswa indlela unyango ngenxa kwawo yayo (ngezantsi-50%). Yena udumile ekuqaleni bomnyango kunye lokuqala experiments helikobakterialnoy isifo.

Ukususwa usebenzisa amayeza ezimbini ine ukusebenza yokulahlwa helicobacter malunga ne-60%, kwaye encinane kakhulu zokwenene namhlanje bakwenza. Yintoni kusetyenziswa namhlanje wokuqeda? iirejimeni zonyango zisetyenziswa.

Tripletoterapiya iquka compound bismuth, i-zintsholongwane (amoxicillin kunye klaritomitsin isetyenziswa kakhulu) kunye imidazoles (oku njengezibulali).

Ikhosi amachiza amane - zonke ezi imixube ngasentla kunye inhibitors pump Proton (eli qela amachiza antiulcer ejoliswe ekunciphiseni imveliso acid esiswini). Iindlela yokufaneleka yalo yokusebenza izalathisi-90% ne-95% ngokulandelelana. Nazi ezinye ngempumelelo nokuphelisa of Helicobacter kunokuba.

Imithi ukuze ukulwisana

Ngenxa yokuba bume asidi uchitha iimpembelelo antibiotics ezininzi, uluhlu amayeza ukuphelisa kakhulu elifutshane:

• antibiotics;
• antiinfectives;
• iziyobisi vismutosoderzhaschie;
• inhibitors impompo Proton;
• probiotics kunye prebiotics.

Amachiza asetyenziswa kakhulu ezisetyenziswa ngokuxhaphakileyo kunyango wokuqeda

Indlela ukuqala ekutshabalaliseni? Antibiotics zezi zilandelayo:

• "Amoxicillin" okanye "Flemoksin Soljutab" - iqela penicillin, into efanelekileyo izigulane ezininzi akukhuthazwa ukuba zisetyenziswe ngexesha lokukhulelwa, ukusilela kwezintso.

• "Amoxiclav" - indibanisela amoxicillin kunye kavulonovoy acid, i spectrum zintsholongwane ebanzi kucetyiswa ukusetyenziswa balumke wayo ezimbi kidney yesigulane, ngexesha lokukhulelwa oonobangela zintsholongwane dysbiosis kakhulu.
• "Clarithromycin" okanye "Klatsid" - phantsi yityhefu zintsholongwane iqela erythromycin uluhlu olubanzi kakhulu zithandwa ukulwisana, leyo contraindicated kwiintsana ukuya kwiinyanga ezintandathu, abasetyhini abakhulelweyo, ayibhalwanga zizazi xa izigulane insufficiency kwezintso okanye hepatic.
• "Azithromycin" - enye indlela 'Klaritomitsinu "ziziphumo ebezingalindelekanga oluncinane, nangona kunjalo, kuyinto efanelekileyo nxamnye helicobacter pylori.

Imithi "tetracycline" yaye "Levofloxacin" zisetyenziswa ngaphantsi rhoqo yaye kwezo meko apho amachiza zikhankanywe ngasentla musa ukuba isiphumo oyifunayo. Imixube tetracycline iqela umboniso amanyathelo ndlongondlongo ngokwemigaqo yeziphumo ebezingalindelekanga emva ngokupheliswa Helicobacter, ngoko wasebenzisa kunqabile.

amachiza Antibacterial kunye anti-infective ukulwisana

"Metronidazole" - anti-infective chemotherapeutic iqela arhente nitromidazolovoy, ayityhefu kakhulu, engahambelaniyo ngqo utywala kunye esalelweyo ngexesha lokukhulelwa.

"Makmiror" okanye "Nufuratel" - ichiza antibacterial, isetyenziswa kwimeko ukusilela "Metronidazole".

Vismutosoderzhaschie iziyobisi

"De-Nol '- oku wasela awaphi amayeza lubonise iqondo eliphezulu lwaze sesichengeni Helicobacter. "Inyibilike De-Nol 'kwaye engena anodaka inyongo kwiingcamba zinzulu welungu achaphazelekayo. ziphumo bezingalindelekanga okugwenxa kuye phantse akukho, kwakunye Izimo (ngaphandle, ngokwemveli, ukukhulelwa).

Ngokuqhelekileyo esetyenziswa ukunyanga Helicobacter yetyuwa iikhompawundi bismuth:

• subsalicylate bismuth;
• subnitrate bismuth.

Amalungiselelo ezisekelwe iityuwa bismuth ezisetyenziselwa ukunyanga izifo zesisu, phambi kokuvulwa Helicobacter pylori. Ezi zinto abanganyangekiyo bume asidi esiswini. iikhompawundi Bismuth phezu isifo ezonakeleyo phezulu ukwenza okukhusela umboniso ukusuka kokusingqongileyo bako, ukunciphisa asidi nokukhuthaza loloyiko bokuqala imiphezulu abachaphazelekayo.

Xa uvula Helicobacter pylori iikhompawundi bismuth lubonise isiphumo eyothusayo kwi ingcinezelo kunye nokonakaliswa oku iintsholongwane ezithile.

Iqela imixube NGOBUCHULE esetyenziselwa wokuqeda

inhibitors impompo Proton (PPI) ezibalulekileyo ukuze isiphumo entsonkothileyo kwi Helicobacter pylori. PPI iziyobisi banale legalelo esesiwini, kunciphisa ndlongondlongo yokusingqongileyo acid. Iintsholongwane Uhlolisiso lubonisa ukuba liphuma bume asidi ife. Ngenxa yoko, PPI ukudala iimeko obungathethekiyo yobukho obutofotofo iintsholongwane kwi yekhabhoni bismuth, "metronidazole" kunye nokwanda zintsholongwane ngempumelelo nokuphelisa Helicobacter pylori kwi-95% nangaphezulu. Ezi amayeza ziquka:

• "Omez" ( "omeprazole");
• "Nolpaza";
• "Rabeprazole";
• "Pantoprazole" njalo njalo.

angala "Omez" eyabelwe rhoqo. Blocker okanye impompo Proton PPI ehla umsebenzi secretion unamadlala yokwetyisa.

Kuqheleke iphecana microflora wokudla emva kutshatyalaliso Helicobacter

Ukuboniswa nemithi kwiimeko ezininzi, iyingozi ukuya emathunjini kunye nesisu. Ngoko ke, emva kokuba iinkqubo yokuphelisa kuyimfuneko ukunciphisa umonakalo owenzeke umzimba. Ukuze wenze oku, kukho ziimveliso ezinoncedo ezifana probiotics okanye prebiotics, esiboniswe dysbacteriosis, flatulence, urhudo, njl Ezi ziquka .:

• "Laktoferon";
• "Linex";

• "Hilak Forte";
• "Bifidumbacterin";
• "Atsipol" njalo njalo.

Probiotics kunye Prebiotics - inkcubeko bohluke kuzo, kakuhle ukuncedisana umsebenzi ngamnye zomnye. Omabini la maqela kuba nefuthe kuyingenelo phezu eziphilayo ngokuthi normalizing izilwanyana emathunjini. Umahluko phakathi kwabo kukuba probiotics - inkcubeko ezincinane siyingenelo ophilileyo. Prebiotics efanayo - iikhemikali organic. I lokuqala ngqo "sikhule" a microflora ofileyo, okwesibini - ukudala iimeko kakuhle oku. Ngokuqinisekileyo kufuneka uthathe emva ngokuphelisa.

zokuthintela izifo

Helicobacter yenethiwekhi pylori efukamileyo inokuba nganye. Le silwanyana uhlala esiswini, emathunjini kunye kwisisu yomlomo okanye isilwanyana kule minyaka kwaye akukho ukuzibonakalisa.

Ukusebenza iintsholongwane kwenzeka ngenxa yokuba kukho ukusilela omzimba phantsi koxinzelelo, imikhwa emibi (utywala, ukutshaya), nezingafezekanga kunye neentlungu epigastric kuziveza. Ezinye iintlobo ze Helicobacter zingachaphazela isibindi.

isiphelo

Ungcoliseko ukususela ekusulelekeni eendaba kwenzeka ngokudibana okanye ngokusebenzisa amanqaku ekhaya. Kufuneka ulandele ngenyameko imigaqo yococeko buqu, ukuze kuncitshiswe nokungcoliswa umntu wesithathu wesithathu. Ngoko ayenzi kufuna ngokupheliswa Helicobacter pylori.