Ukulungiswa kwemithi 'Azitsid', imiyalelo yokusetyenziswa, ukuchasene

I-Antibiotics yoluhlu oluninzi lwezenzo, ulungiso "U-Azitsid", luvela kwiqela lama-macrolides (azicides). Le nkunkuma isebenza ngxininiso ephezulu yezinto ezisebenzayo - i-azithromycin - ekugxininweni kwintsholongwane, ukudala ukhuselo lwe-bactericidal. Kukho umsebenzi ophezulu weziyobisi ezichasene ne-gram-positive bacteria, kwaye ngokuchaseneyo, ayichaphazeli ibhakteria ye-gram-negative, ebonisa ukuchasana no-erythromycin.

"I-Azithromycin" ayixhatshali kwi-acidic medium, ngoko ukutshatyalaliswa kweyeza kuvela kwindlela yokugaya. Isilwanyana sifinyelele ekuxininisekeni kwiplasma yegazi emva kweeyure ezingama-3, i-37%. Kufuneka kuqatshelwe ukuba luncedo lokungenelela kwimizimba ye-urogenital kunye nezicubu, indlela yokuphefumula, izicubu ezithambileyo kunye nesikhumba sokulungiselela "u-Azitsid", umyalelo wokusetyenziswa uchaza oku ngokuzibophelela kwiiprotheni zegazi. "I-Azithromycin" ihanjiswa ngama-phagocytes kwiindawo zokuxinwa okuphezulu kwentsholongwane kwaye ikhutshwe kwinkqubo ye-phagocytosis, ngaphandle kokusebenzisa imiphumo emibi kubo.

Ngethuba leveki le nkunkuma iyakwazi ukuqhubeka nokugxininisa okuphezulu kwi-infection ye-infection, i-substance esebenzayo ihoxiswa kwizigaba ezi-2, oku kukuvumela ukuba uthathe amayeza kanye ngosuku.

Izifo ezivuthayo zezifo ezahlukeneyo zibonakaliso zonyango kunye nokulungiselela "i-Azitsid", imiyalelo yokusetyenziswa ibhekisela kwizifo ezinjalo, ezibangelwa zizilwanyana ezincinci kwisifo. Oku kubandakanya izifo ezilandelayo:

- urogenital;

- umgangatho ophezulu wokuphefumula, umzekelo, i-tonsillitis, i-tonsillitis, i- otitis media , njl kunye nezitho ze-ENT;

- ngaphantsi kwendlela yokuphefumula, umzekelo, i-pneumonia ye-atypical;

Izicubu zesikhumba kunye nezilwanyana ezincinci (impetigo, i-dermatoses yesibini);

- izigaba zokuqala zesifo seLyme;

- Izifo ze-duodenum, i-patasty gastric pathology.

Xa ucacisa unyango, kuyimfuneko ukulandela irejimenti yesilinganiso sokulungiselela "i-Azitsid", umyalelo wokusebenzisa ukucebisa ukuthatha iyeza emva kokutya kanye ngosuku ngemilinganiselo emiselweyo ngabanye.

Kwimiqathango yamalungu omzimba, iziphumo ezibi zingenziwa ngenxa yokusetyenziswa kweziyobisi "Azitsid", umyalelo ubiza ukuba kubekho ukubonakaliswa okungekho mvelaphi kwinkqubo yesondo kunye neyayisisigodi, ngesimo sengqondo esilungileyo okanye se-dermatological. Kubantwana, unyango kunye neziyobisi lunokubangela ukubetha, i-conjunctivitis, okanye imihlathi.

Ubuthakathaka obukhulu kunye nokungaqiniseki ngokuthe tye kubonwa njengesisombululo sokupheliswa kweyeza kunye neziyobisi "Azitsid", umyalelo wokusetyenziswa kweefowuni ezinye iinkcazo ezingaphezulu kweli phepha:

- abantwana abangaphantsi kweminyaka eyi-3 okanye ubunzima bomzimba obungaphantsi kwe-25 kg:

- uvakalelo oluphezulu kwiziyobisi:

- uvakalelo oluphezulu kwii-antibiotiki zeqela le-macrolide.

Ukwelashwa nge "Azitsid" ngexesha lokukhulelwa kunokwenzeka, kodwa kuphela kwimeko yokuphakama kweenzuzo zokuthatha le nkunkuma kumfazi phezu kwengozi ebantwini.

Xa ukugqithisa kweziyobisi "Azitsid" kugcinwa iimpawu ezifanayo kunye nemiphumo emibi, kodwa zibonakaliswa kwifomu ekhutshisiwe. Ingaba ukuhlanza, isicuphoso esinzima kunye nesifo sohudo, ukulahlekelwa kwindlebe yesikhashana kunokwenzeka. Njengoko unyango, qalisa i-charcoal, ukugcoba isisu kunye nezinye izifo zonyango.

Ngaphambi kokuba kuqeshwe izilwanyana "Azitsid" njenge-arhente yonyango, ingqalelo ekhethekileyo kufuneka ihlawulwe ekusebenzisaneni kwayo namanye amayeza. Okokuqala, iya kukhusela ngokugqithiseleyo, okwenzekayo ngenxa yokuqiniswa kwamanye imali. Ngokomzekelo, ukusebenzisa i-"Azitsid" kunye ne-digoxin, kukho ukuxinwa okwandisiweyo kwimizimba yokugqibela, kunye ne-chloramphenicol kunye ne-tetracycline kwandisa umphumo we-azithromycin. Iziganeko ezifanayo zokusebenzisana kwezidakamizwa zichazwe ngokucacileyo kwimiyalelo kwiyeza.

Ubuninzi be-shelf-ubomi bonyango yiminyaka emi-2, igcinwa ngaphandle kofikelelo lwabantwana kunye nendawo epholileyo.