Nicotinic acid: ezibonisa ukusetyenziswa, ziziphumo ebezingalindelekanga, ixabiso

Niacin abanokuzifumana umzimba womntu iziphumo ezahlukahlukeneyo. Oku kuvumela ukusetyenziswa kwayo ukuze ukunyanga izifo ezininzi kwegazi, nesisu namathumbu, kwakunye izifo nokuphuhlisa kwisiqalo ngenxa yamafutha kunye pellagra.

Thatha inxaxheba nethe beziyobisi

Niacin ithatha inxaxheba kuzo zonke iinkqubo ukutya - yaye ngakwicala leeprothini kunye namanqatha, kunye ekudleni. Oku kwenzeka ngenxa yokuba yinxalenye enzayim ekukhawuleziseni igcwala kunye nokunciphisa ngayo.

Ingakumbi iziyobisi esebenzayo kuchaphazela nethe kwamafutha. Kusiza ukuncitshiswa yegazi (ingakumbi i "okubi") ekhuthaza ukuyilwa umonakalo kwimikhumbi yegazi. Inani organic ezimbaxa luncedo leyo inxaxheba inxaxheba kwiinkqubo pathways, naye uyakwazi kwandisa nicotinic acid. Iimpawu zibonisa ukuba ukusetyenziswa kweziyobisi ngenxa yezi zizathu, ezi zilandelayo: uninzi izifo ukuphuhlisa kwisiqalo ngenxa yamafutha, ezifana nesifo esimbaxa occlusive (peripheral esimbaxa occlusion), isifo kobuchopho zobuchopho kunye nentliziyo.

ukukhawulezisa lokuhamba kwegazi

Ukongeza, nicotinic acid wenza ukwandisa ngendlela phezu emithanjeni (imithambo yegazi). Uxhasa hawu igazi nokuphucula unikezelo amalungu alo ahlukeneyo. Ngoko ke, uyakwazi ukukhawulezisa izihlunu ngokutsha, inxeba nezilonda ephilisa kunye nicotinic acid. Iimpawu zibonisa ukuba ukusetyenziswa kweziyobisi kulo mzekelo: izifo ezininzi emathunjini kunye nesisu esweni (phakathi exacerbations).

enquma

Ichiza lokuqala inceda kwi unyango pellagra. Esi sifo senzeka ngenxa intswelo na nicotinic acid. Oku kuphakamisa yokuphazamiseka yokucolwa akhokelela sisilonda esidumbileyoesingaphakathi ulusu, kuphinde oko emsebenzini ukurhawuzelela, ukudumba, ukuba bomvu. Kwakhona, umsebenzi emathunjini uphazamiseke xa pellagra, isisu (kuquka neentlungu kunye neelwimi), ingqondo (isiphumo - dementia). Kwimeko uphuhliso engephi kwesi sifo kunye nokungabikho zinganeziphumo ezibi kakhulu central system luvo nicotinic therapy acid kuyaphumelela kakhulu.

izifo esiswini namathumbu Treatment

Kuba unyango ezimbi leyo usasebenzisa nicotinic acid? Iimpawu zibonisa ukuba ukusetyenziswa kweziyobisi isenokuba kulandelayo - iindidi zezifo emathunjini kunye nesisu. ezizezi:

1. Gastritis kunye nokuphungulwa secretion.
2. isilonda Duodenal wesisu.
3. Besisu.
4. Enteritis.
5. Pancreatitis ifomu ezigulo ezondeleyo.

Kuzo zonke ezi meko, ukusetyenziswa nicotinic acid wamahashe kuphela kuxolelwe (hayi ngamaxesha exacerbation). ngokukhethekileyo kuyimfuneko ukusebenzisa eli chiza xa kunyango kwethumba Peptic, ekubeni ukuze kukhawuleziswe esiswini acid secretion ngexesha exacerbation. Ngenxa yale vasodilation kunokwenzeka esa iingxaki ukopha kunye nezifo.

malabsorption syndrome

Kukho kwakhona izifo esiswini kunye emathunjini, nto leyo ziyakwehlisa ngokubonakalayo izinga ukufunxeka macandelo kokutya emathunjini amancinci kunye nicotinic acid. Le ngezifo ubizwa ngokuba "malabsorption syndrome". Uhamba izifo ezininzi ephuhlisa kwisiqwenga zesisu. Nale syndrome ilawula isabelo nicotinic acid wavelisa yegazi okanye intramuscularly.

Ukuswela acid

Kubalulekile ukuba nicotinic acid ukunqongophala uyaqapheleka emzimbeni xa kuthe ukungondleki. menu njalo ngokusekelwe iintlobo zemveliso, xa kungekho lwesilwanyana abakudlayo protein, iziqhamo kunye nemifuno akamvumeli ukuba Akothusi ukufumanisa inkqubo kwaye amalungu omzimba ngokwaneleyo kuyo. Xa kunjalo, i medicament ilawulwa ngomlomo okanye ngenaliti.

Kwakhona, nicotinic acid ngxaki kwenzeka ngenxa kakhulu izifo ezosulelayo uhlobo sikhatshwe ukwanda okubonakalayo lobushushu emzimbeni ngenxa komtshiso oko ixesha elide. Xa eli chiza unikwa kuphela ngaphandle ixesha exacerbation. Kwimeko kohlobo okanye isibindi kwesibindi nicotinic acid lisusiwe.

nezinye izifo

Ziziphi ezinye iimeko, a nicotinic acid? Iimpawu kungabandakanya oku kulandelayo:

1. Yamafutha kunye nezifo ezinxulumene nayo - endarteritis obliterans, isifo sentliziyo kobuchopho. Ukusetyenziswa acid ibalekisa cholesterol ukutya, dilates imithambo yegazi, uphucula igazi ubonelelo ancedisana amalungu.
2. izilonda Trophic namanxeba. Niacin inegalelo ngokutsha inyama kwangethuba impiliso.
3. Ukubuyiselwa eqhelekileyo yokusebenza amalungu amaninzi. Le medicament, kule meko lisebenza njenge vitamin.

Nicotinic acid: Imiphumela Side

Yamkela grams medicament eyamkelekileyo hayi ngaphezulu kwe-6 emini. Ukuze ufumane uluvo olungcono nicotinic acid ngawo umzimba kufuneka ziphele kuphela emva kwesidlo ze usele isiselo efudumeleyo. Xa lokuqala unyango ngamachiza nale imfuneko yokulawula kwinqanaba glucose egazini. Kwakhona ukuqaphela iziphumo ebezingalindelekanga acid kufuneka esweni umsebenzi kwezintso.

Maxa wambi ichiza yakhiwe tenxileyo waqonda zizigulane, maxa wambi anozizi eluswini, ize idanyaze ezishushu. Isizathu soku ke lenjini okwandisiweyo prostaglandins, yokuphazamiseka iphecana zesisu, hyperuricemia nokuncipha impendulo iswekile. Ngenxa yesi sizathu, olusebenzayo, kodwa ngeedosi elikhulu nicotinic acid (3 ukuya kwezi-5 grams ngemini) ayikwazi ukwenza twisisa ephilayo nganye.

Imiphumo yityhefu ye ichiza

Maxa wambi Le idepho iziyobisi ibanga iziphumo kakhulu yityhefu kwi esibindini. Ngoko ke, sebenzisa ixesha elide nicotinic acid angenela control kulo mzimba. imiphumela loo ichiza ophezu kwesibindi ngenxa kwesipirithi yayo. Phambi kokuba uqale ukuba ibonakalise iziphumo hepatotoxic of nicotinic acid kakhulu sehlise izinga lipids egazini.

hypovitaminosis

Ixesha elide ukusebenzisa nicotinic acid kukuninzi kukhokelela ukubana yomzimba ascorbic acid. Le nto ibizwa ngokuba hypovitaminosis. Ukuthintela oku, ulawulo olongezelelweyo uthathwa amalungiselelo afanelekileyo ze ascorbic acid.

Okunye ezinxaxhileyo

Xa ukusetyenziswa nicotinic acid njengoko nguqu zilandelayo ukuze ziqwalaselwe:

1. Ukwandisa asidi yejusi esiswini (ukuqhubela phambili isilonda).
2. Hyperglycemia.
3. Ukwanda nezihlandlo arrhythmias atrial kwizigulane kunye nesifo semithambo kwimithambo (inqabile, kodwa kunokwenzeka).
4. Imbonakalo, akhanya ngokuba inshorensi velvety kwesikhumba (acanthosis).
5. Ekweneni retina kwamehlo (a isiphumo kwicala ezinqabileyo).

Zonke ezi mpawu abasakwazi ingazinzi kwaye shwaka emva engasayi nicotinic acid.

Ixabiso beziyobisi

Yimalini niacin? Price of Pharmacy Russian zazisuka 10,90 engange. tablet 50 umthamo we 0.05 grams. Elona xabiso liphezulu - malunga 81 engange-10 nengqayi beziyobisi umthamo we-10 mg / ml.