Ngezakhi zofuzo

therapy Gene - le unyango ilifa non-ilifa, izifo multifactorial, nto leyo ikhutshwa phandle ngokuqalisa zezilimo ibe ezinye iiseli nomonde. Injongo unyango kukuba ukuphelisa iziphene yemfuza okanye enika iiseli izinto ezintsha. kulula ukungena kwi iseli esempilweni, ukusebenza ngokupheleleyo gene, kunokuba alungise iziphene ezikhoyo.

therapy Gene kuphela izifundo kwizihlunu somatic. Oku kungenxa yokuba naluphi na uphazamiseko nomntu wesini kunye osandul iiseli anganika iziphumo ukwazeka kakhulu.

Okwangoku indlela asebenza iyasebenza ekunyangeni izifo zombini monogenic kwaye multifactorial (nangezilonda yingozi, ezinye iintlobo zezifo enzima sentliziyo, izifo wentsholongwane egazini).

Malunga ne-80% azo zonke iiprojekthi ezinxulumene ngezakhi zofuzo, usulelo lwe-HIV kunye nesifo somhlaza. Okwangoku, uphando luqhutywa ezifana izifo ilifa njengoko kubazali bakhe B, isifo Gaucher kaThixo, abanesigulo esinganyangekiyo, hypercholesterolemia.

Unyango lwezifo zofuzo kubandakanya:

· Ukukhethwa andise lweentlobo ngamnye leeseli umguli;

· Ukuqaliswa zofuzo amazwe;

· Ukukhethwa leseli apho i "babanjwa" sofuzo angaphandle;

· Umzila kwisigulana (umz, ngalo igazi).

therapy Gene isekelwe kusungulo DNA eyenziwe ibe nezihlunu isigulane. Eyona ndlela isebenzayo zithathwa zokugonya injectable njesitsitsi.

therapy Gene usebenza ngeendlela ezimbini:

1. Unyango lwezifo monogenic. Ezi ziquka ukuphazamiseka ebuchotsheni ezihlobene nayo nayiphi na umonakalo iiseli ezibangela neurotransmitters.

2. Unyango lwezifo zamafa. Iindlela eziphambili asetyenziswe art:

· Uphuculo Genetic weeseli omzimba;

· Ukwandisa immunoreactivity le ithumba;

· Block amazwi oncogenes;

· Ukukhusela iiseli ezinempilo ukusuka ichemotherapy;

· Izakhi Igalelo ithumba suppressor;

· Ukuveliswa arhente anti-ithumba iiseli uphilile;

· Ukuveliswa zokugonya antitumor;

· Ukudlalwa Local izicwili eziqhelekileyo ngokusebenzisa Antioxidants.

Ukusebenzisa ngezakhi zofuzo ineendlela ezininzi, kwaye kwezinye iimeko nguye ithuba kuphela ubomi obuqhelekileyo abantu abagulayo. Noko ke, le ndawo isayensi ayiqondwa ngokupheleleyo. Kukho ukuvalwa yamazwe ngamazwe malunga ucikido esini kunye pre-umzila iiseli osandul. Oku kwenziwa ukuze kuthintelwe uyakha gene okungafunwayo zofuzo.

Ngophuhliso kunye wavuma ezinye iimeko apho ulingo lwezonyango bavunyelwe:

1. Zezilimo idluliselwa kwizisele ekujoliswe kulo, kufuneka isebenze ixesha elide.

2. Imeko gene ezingaqhelekanga kufuneka agcine ukusebenza kwayo.

3. transfer Gene akufuneki baxabane elibi emzimbeni.

Kukho intaphane yemiba kuhlala ezifanelekileyo namhlanje yaye izazinzulu ezininzi ehlabathini lonke:

• Ngaba izazinzulu abasebenza kwicandelo ngezakhi zofuzo, ukuze kuphuhliswe genokorrektsiyu ngokupheleleyo ukuba akusayi kubangela isoyikiso bobempunde?

• imfuno kunye luncedo unyango ngezakhi zofuzo, ukuze isibini esithile baya Zizigqithile ingozi yokuphazamiseka kwikamva loluntu?

• Ukuba iinkqubo ezo wabagwebelayo, banikwe nobuninzi ngayo emhlabeni kwixesha elizayo?

• ukuba babalise iinkqubo ezifanayo abantu imibuzo homeostasis ongqonge umhlaba onokuphila kunye noluntu njani?

Xa ndiqukumbela, kufanele kuphawulwe ukuba unyango yemfuza kwi langoku ibakala uluntu inikeza iindlela ukuze ukunyanga izifo ezininzi kakhulu ukuba kude kusanda ingqalelo asikuko nokuba kuyabulala. Kodwa ke, kwangaxeshanye, uphuhliso le inzululwazi silindelwe izazinzulu imingeni emitsha ekumele zilungiswe namhlanje.