Kanye malunga neziyobisi "Octreotide": imiyalelo yezigulane

Abaninzi babeza kunika imali eninzi ukuba babe phezulu, ngakumbi kubantu. Kodwa kuphela i- hormone yokukhula emva kokufikelela kwiminyaka ethile engasakwazi ukuyichaphazela, kunoko iyakhula ngokwanda kwesilungu - le meko ibizwa ngokuba yi-acromegaly. Kukho into enjalo inqabile. Nangona kunjalo, abo bahlala besifo ngenxa yeso sifo, ixabiso leziganeko alibalulekanga, kubalulekile kubo-ngaba kunokwenzeka ukuba balwe nesifo? Ewe, kunokwenzeka, kula maxesha, i-Octreotide imiselwe.

Umyalelo, ngaphandle kwe-acromegaly, ukhankanya nezinye izifo njengezibonakaliso. Ngokomzekelo, i-tumor ye-pancreas nesisu. Inyaniso kukuba i-peptide eyingxenye ye-Octreotide igxothisa inxaxheba yokungabikho kuphela kwe-hormone yokukhula. Kwakhona, ukuhlanganiswa kwe-glucagon kunye ne-insulin inqande kakhulu. Ngokuqhelekileyo, esi siphumo sinomzimba we-hormone somatostatin, kodwa umphumo omkhulu kunikwa ngu-Octreotide. Umyalelo uthi ezi zinto zimbini zifana nezokwakheka kweekhemikhali, kodwa iyeza zisebenza ngokugqithiseleyo ngenxa yempawu ezithile zekhemikhali. Isenzo saso sininzi kakhulu kunemiphumo ye-somatostatin. I-Octreotide iphinda iphazamise ukuhlanganiswa kwezidalwa ezinjenge-hormone kwisistim sokutya. Ngomdlavuza, isondlo sesisu sisisiphumo esihle, kodwa ukuba isigulane siphathwe nge-acromegaly, ngoko kuba ngumphumo wecala, akusoloko unqweneleka.

I-Acromegaly ayikho nje ukunyuka kwamalungu. Kwakhona ukuvuvukala, intloko, ubunzima bokuhamba ngenxa yokuphazamiseka kwamalungu. Zonke ezi zimpawu zisuswe ngempumelelo ngokusebenzisa izidakamizwa i-Octreotide Long. Izibilini ze-Benign zinciphisa ngobukhulu ngenxa yokusebenzisa le mayeza. Izidumbu ezinobunzima ngokusayizi azincinci, kodwa ubunzima beempawu zesifo ziyahla. Oko kukuthi, unyango lwe-adenomas luphucula imeko jikelele, kodwa nge-carcinomas ithola uphawu olubonakalisa uphawu.

Ukuba isiguli sinyuswe ngama-hormone-like like tractinal tract, i-Octreotide iphumelela ngokulwa nesifo sohudo, isifo sesifo, xa ukulawulwa kokutya kuphazamiseka ngenxa yokuveliswa ngokungaqhelekanga kwemigaqo "yangaphakathi".

I-Octreotide inceda kwakhona kwi-30% yazo zonke iimeko zesifo sohudo oludityanisiweyo, oluqhelekileyo lwegulane ezininzi zeAIDS. Nangona kunjalo, eli phesenti alinakulungele ukuba liqwalasele eli liyeza njengethuluzi elithembekileyo.

Baya kuphi na umyalelo we-Octreotide? Umyalelo uphinde uchaze iimeko emva kokusebenza emva kwee-pancreas. Esi sidakamizwa sinokunciphisa kakhulu amathuba okuba neengxaki, umzekelo, ukwakheka kwe-sepsis kunye ne-fistula, i-abscess kunye nokutshabalala kwangemva kwesithuba - ukuphazamiseka kwe-pancreatitis.

Nge-acromegaly, isicatshulwa sijojowe phantsi kwesikhumba kumanani amancinci (angabi ngaphezu kwe-0.1 mg) imihla ngemihla. Umphumo wonyango kufuneka uvele kwiinyanga ezintathu. Ukuba ayithethi, isicatshulwa sihoxisiwe kwaye ezinye iindlela zifunwa ukusebenzela ingxaki. Kodwa ukungabi namdla ku-"Octreotide" kunye ne-acromegaly ayiqabile kakhulu.

Ukuba i-tumor tumors iphathwa, i-dose ingaba kabini kakhulu njengonyango lwe-acromogaly. Iliphi unyango lilawulwa kabini ngosuku, kwakhona luphantsi kwesikhumba.

Nangona kunjalo, ukuba usebenzisa i-octreotide-Depot, izilwanyana zenziwe ngendlela eyahlukileyo, kwi-gluteus muscle, zenziwa rhoqo iintsuku ezingama-28 kwaye inkunkuma ijojowe kakhulu. Le ndlela inenzuzo, nangona inkqubo ibuhlungu kakhulu.

Ngaba zikhona na iziphumo ezimbi zeOgotreotide? Umyalelo uchaza ukuphazamiseka kokugaya, i-cholelithiasis, ukuphulwa kwe-sugar metabolism.

Ugqirha onolwazi uya kugqiba isigqibo sokuba ngaba u-Othoreotide uyamisela kwimeko yakho.