Isiza "Buserelin". Imiyalelo

Iyeza "iBuserelin" ibhekisela kwiqela le-pharmacological yama-antitumor agents kunye nama-hormone antagonist. Amachiza afumaneka njengesisombululo somjovo. Isilwayo senziwa kwakhona ngamaconsi olawulo lwe-intranasal. Kwii-pharmacy, zingathengwa kwaye kwi-vial, umthamo wayo uhambelana namayeza angama-aerosol (i-spray spray).

Isilwanyana "iBuserelin", umyalelo ozisa ukubunjwa kwesi sidakamizwa, njengokuba isithako esisebenzayo siqukethe i-buserelin acetate. Into encedisayo ejoliswe ekulondolozweni yi-benzyl alcohol.

Isilwanyana "iBuserelin" ngumfanekiso we- hormone yemvelo ye- gonadotropin-ukukhululwa, ehlanganiswa yindlela yokwenza izinto. Isilwayo sinqunywe kwindlela yokunyanga kwezidumbu ezinemvelaphi ye-hormonal. Isilwayo "iBuserelin", umyalelo ochaza ngokucacileyo indlela yokusebenza kwayo, unokwandisa inani lamahomoni asegazini, ngenxa yokuchaphazela ngqo kwi-gland gland. Kwiintsuku ezingama-12 ukuya kwe-14 emva kokuqala kwesilwanyana, ukuveliswa kwe -hormone yokuvuselela i- luteinizing ne- follicle kwi-ovaries yezigulane. Oku kubangelwe ukukhutshwa kweprogram ye-gonadotropic kwintsimbi ye-pituitary.

Ngako oko, ukuhlanganiswa kwama-hormone wesondo kwi-ovary kupheliswa kwaye inani le-estradiol kwi-plasma yegazi liyancipha, obangela ukuphazamiseka komjikelezo wesini. Xa unyango lwe-oncology ye-prostate, ukusetyenziswa kwexesha elide leziyobisi kunciphisa umgangatho we testosterone, obangela ukuba "i-drug castration". Imfuno yokuphelisa imveliso ye-hormone iyenzeka kunyango lwe-hormone-type cancer. Ngokomzekelo, ngomhlaza wesibeletho okanye umdlavuza webele. Kwiimeko ezinjalo, i-hormone yesini ikhupha ukunyuka kubukhulu besisu. Emva kokuba isicatshulwa sihoxisiwe, inani le-testosterone ne-estrogen equlethwe kwigazi liqhelekile. Inyanga emva kwe "Buserelina" ibuyiselwe ngokuzimela emva kokupheliswa kweendlela. Xa ulungiselela ukusebenza kunye ne-endometriosis, injongo yeziyobisi inokunciphisa ubukhulu be-patciosis kunye nokunikezelwa kwegazi, kunye nokunciphisa ukuvuvukala kweendawo ezichaphazelekayo. Ukusetyenziswa kwesilwanyana kwixesha elimva emva kokunciphisa kunciphisa inkqubo yokunamathela kunye nexesha lobunzima.

Isilwayo "i-Buserelin", umyalelo ochaza i-pathologies ephambili ekulawulwa kuyo, iyacetyiswa ukukhathazeka kwe-hormonal. Ezi ziquka:

• I-oncology yebele;
• Endometriosis;
• I-myoma yamanzi;
• I-endometrial hyperplasia;
• I-oncology ye- prostate.

Isilwanyana sisetyenziselwa unyango lokungabikho.

Isilwayo "i-Buserelin", umyalelo osilumkiso malunga neziphumo ezingathandekiyo ezinokuthi zenzeke xa uthabatha, kunokubangela intlungu kunye nokuphazamiseka kokulala, ukudandatheka kunye nokucasula kwe-retina (ukuba isigulane sigqoke ii-lens). Kwakhona, isicupunu kunye nokuhlanza, utshintsho kwisondlo, ukungabi namandla kunye nokuma komzimba wesisu, intlungu kwisisu esezantsi kunye ne-cyst ovarian Ngamanye amaxesha, ukuthatha amayeza kunokubangela ukucaphuka kwe-mucosa yomlomo ngokubonakala kwegazi, ukutshisa okutshisa, ukunyuka kwesikhumba, owomileyo owomileyo, ukuchithwa kwemithi yamathambo, i-gynecomastia, i-thrombosis, nokuvuvukala ezinyaweni nasezintanjeni. Esi sidakamizwa asivunyelwe ukuthatha ngexesha lokuncelisa umntwana, kwakunye nokukhulelwa.