"DITT Depot": imiyalelo ukusetyenziswa, Izimo, ziziphumo ebezingalindelekanga, ukubuyekeza, iifoto

Yintoni na oyaziyo olu nyango, ezifana "DITT Depot"? Imiyalelo yokusebenzisa, Izimo, uhlolo kunye neziphumo ebezingalindelekanga ichiza ziya kuqwalaselwa ngakumbi.

Packaging kunye nefomu ichiza, lakhiwe

Ziziphi ifomu ukuvelisa ichiza njengoko "DITT Depot"? Imiyalelo iingxelo zokusetyenziswa ukuba zingathengwa ngohlobo isisombululo olunamafutha ukuba isitofu intramuscular. Eyona nto iphambili esebenzayo yale ichiza fluphenazine decanoate. Njengoko engena intengiso ampoules zeglasi emnyama, pre-apakishwe esiseleni nentaba kunye nephepha Imiqulu, ngokulandelelana.

Pharmacology

Zeziphi iimpawu amayeza medicament semvelo "DITT Depot"? Imiyalelo yokusebenzisa, ncomo bathi oku ixesha elide-esebenza amayeza antipsychotic. Lukamongameli kwiqela neuroleptics polyvalent kunye nemiboniso zomlomo iimpawu antipsychotic, apho kudityaniswe asibambe nefuthe antiemetic. Kwakhona, eli chiza nemiphumo wobulali umthomalalisi.

Yintoni ebangela ukusebenza ichiza "DITT Depot"? Imiyalelo yokusebenzisa ithi neziphumo zayo antipsychotic enxulumene kuvalwe iindlela dopamine D2 receptors Mesocortical kunye neenkqubo mesolimbic.

Iipropati okulalisa yale medicament kwaye abangaxhalabisiyo wavakalisa waphawula kuphela xa amathamo eziphakamileyo isicombululo. Kokuba babe balindeleke ukuba kuvalwe iindlela receptors adrenergic zamacandelo ngamnye izikhondo ebuchotsheni.

Ngokumalunga imiphumo anti-emetic le amayeza, ngoko linxulunyaniswa kuvalwe iindlela dopamine D2 receptor aqala izowuni iziko egabha. Kufuneka kuqatshelwe ukuba isiphumo hypothermic kweli chiza ibonisa ukuba kuvalwe iindlela receptors dopamine le ngxenye.

Zingaphi isiyobisi uqalisa ukwenza 'DITT Depot "? Imiyalelo (isisombululo ziphene photo thaca kwiphepha) ukusetyenziswa ingxelo ukuba isiphumo konwaywa ichiza idla wabonakalaliswa emva kweeyure 25-72 emva kokuba isitofu. Kufuneka kuqatshelwe ukuba iimpawu ichiza antipsychotic phantsi ingqalelo ezichatshazelwe kakhulu awasiwisayo kwisithuba iiyure 49 ukuya 97 emva kulawulo isicombululo.

Le kinetics beziyobisi

Yintoni Lubalasele pharmacokinetics beziyobisi "DITT Depot"? Imiyalelo yokusebenzisa okufunwayo fluphenazine ngohlobo ezinto isisombululo eliphezulu oyile ubunzima Ester okunamafutha acid nga angakhuli kwiindawo ekuthelwa kuzo adipose, ngokunjalo bakhululwa nje kancinci.

Emva Inaliti intramuscular of a xi iphezulu element iyazalisekiswa emva kweeyure 25 plasma. Kulo mzekelo, fluphenazine enebana ubonelelo igazi 90%.

iziyobisi kujongwa lula iwela umqobo placental kwaye udlula negazi-ingqondo, kwaye kwazona yi olugqitha esikhumbeni.

Fluphenazine ngokupheleleyo yaye ngokubanzi ezetyiswa ngayo yi inkqubo isibindi enzyme ebandakanya P450 cytochrome. Ukusuka umzimba kubhaliwe kwizondlo kunye enyongweni kunye nomchamo. metabolites Active lwesi sakhi akukaqondwa kakuhle.

Fluphenazine isiqingatha-ubomi iiyure 7-10.

ubungqina

Kwezinye iimeko, isigulane emiselweyo iinaliti "DITT Depot"? Imiyalelo yokusebenzisa ibhekisela bubungqina ezifana:

• exacerbation ngesifo (ukuvimbela);
• unyango ulondolozo elide ngesifo esinganyangekiyo.

Siphelisa ukusetyenziswa

amayeza kujongwa akuvumelekanga kwezi meko zilandelayo:

• phantsi kwezifo SS enzima, kuquka ne ukusilela decompensated ezingapheliyo yegazi kunye hypotension;
• kwi ubuntununtunu ephakamileyo isigulane fluphenazine, kwakunye nezinye izinto ze ichiza;
• abaxinzelelweyo ngexesha CNS kunye ithi comatose;
• ngexesha lokukhulelwa;
• e skull umothuko kunye nezifo phambili lwenkqubo yemfundo ingqondo kunye umnqonqo;
• ekondleni;
• ne umsebenzi kwesibindi kakuhle kunye nenkqubo igazi;
• ukuya kutsho kwiminyaka eli-12.

Ukusetyenziswa ngononophelo iziyobisi

Balumkele "ichiza DITT Depot 'olumiselweyo:

• butywala, kwakunye nokwanda susceptibility ukusabela hepatotoxic;
• utshintsho yezifo egazini, kwakunye nokunyhashwa hematopoiesis;
• allergies phenothiazines, kuquka imbali;
• ukuvalwa glaucoma;
• umhlaza webele;
• hepatic kunye / okanye ukusilela kwezintso;
• nezilonda ye phecana wokudla, kuquka ixesha lokugula ahlekise;
• hyperplasia prostatic kunye ekubonakalisweni clinical;
• myxedema;
• izifo, ephelekwa iingxaki thromboembolic;
• isifo Parkinson kaThixo;
• izifo ezingapheliyo kunye ukusilela ngokuphefumla (kuquka abantwana);
• syndrome Reye kaThixo;
• sokuwa, ukugabha, ukuxhuzula;
• cachexia;
• ebudaleni.

Isisombululo iziyobisi "DITT Depot": imiyalelo yokusebenzisa

Le ampoules kweli chiza senzelwe kwizifundo ixesha elide unyango (ubuncinane iinyanga ezintathu). umthamo wakhe wokuqala kwizigulane kakhulu 12.5-25 mg. amathamo elandelayo, kwakunye lekhefu phakathi izitofu yezisombululo azimisele kuxhomekeke phezu isiphumo therapeutic.

Unyango kwezigulane hypersensitivity ukuya phenothiazines kufuneka ziqalwe ngokuqaphela kakhulu.

Abadala ifuna ukuqeshwa amathamo aphantsi izigulane abancinane (malunga 1/4 ukuya 1/3 ye umthamo). Kulo mzekelo emva kwabo kufuneka kweliso rhoqo.

Izenzakalo by-lomsebenzi

Isisombululo iziyobisi "DITT Depot" kungabangela indlela ezingathandekiyo zilandelayo:

• syndrome extrapyramidal, akathisia, zeDyskinesia tardive, ekuboneni, ubunzima oculogyric, hyperreflexia, opisthotonos;

• syndrome neuroleptic yingozi, leyo lunokubulala;
• hypotension intolerance, ukubila, ukuhla uxinzelelo lwegazi, isicaphucaphu, hypotension, ukungabi namdla, glaucoma, ukuvuza izinkcwe kakhulu, atony isinyi, polyuria, kwesisu isithintelo, umlomo owomileyo, tachycardia, intloko ebuhlungu, ukungaboni, ukuqhina, ingxinano ngeempumlo;
• arrhythmias ventricular, ukufa ngesiquphe, tachycardia ventricular, zokuma;
• zisanyisa okungaqhelekanga, nokudumba peripheral, ukuphazamiseka sexesheni, hyponatremia, namandla emadodeni, utshintsho ubunzima bomzimba, utshintsho yobuntu kwabasetyhini;
• pruritus, dermatitis exfoliative, erythema, seborrhea, urticaria, reactions anaphylactic, photosensitivity, angioedema, spasm inyumoniya, nokudumba laryngeal;
• agranulocytosis, leukopenia, senyongo cholestatic;
• ukuxhuzula, umkhuhlane, utshintsho ECG, diskinenziyu vuhlayiseki, ukugabha, thromboembolism lwemithambo, lupus-ezifana syndrome, kunye nabanye.

baqinisekiswa

Ngoku, uyazi, yintoni na kuqhume "DITT Depot." Imiyalelo yokusebenzisa, side effects, kunye Izimo ukusetyenziswa kwale sisombululo iye kuxoxwe ngasentla.

Ngokutsho izigulane iphathwa ngaphambili kunye namachiza ezahlukeneyo antipsychotic, ichiza "DITT Depot" isebenza kakhulu kakuhle kakhulu kwaye ususa zonke iimpawu ngesifo ezimbi. Ukuqaliswa kwale ichiza kakhulu oluzinzileyo kunye noxolelo ixesha elide.

Le ethile kuphela esi sixhobo na isixa omkhulu ngu-lomsebenzi ngayo. Ngemihla zokuqala unyango kwezinye abantu ephawulwe komzimba, lwegazi kunye nokuphazamiseka yawo. Kwakhona, izigulane ezininzi zinyangwa izihlunu giperkinezy zomlomo ubuso, imitya imilebe yakhe kunye nentshukumo nolwimi. Ngaphezu koko, ukusetyenziswa kweli chiza ezidla ngokubangelwa ukudakumba ngegalelo ubungnqongqo.