Creatinine - sisithethe egazini kunye nomchamo. Ukubaluleka kwe sample

Creatinine - omnye umlinganiselo chemistry igazi kunye urinalysis. Xa chemistry lwezonyango oko kumiselwa isikakhulu ukuhluza uphando reabsorbtsionnoy kunye nemisebenzi sezintso. Kuba gqirha, creatinine, isantya sokukhula lwezidumbu okanye uthetha lukhulu. Kodwa ke makhe siqale sihlole le nto nendlela oveliswa emzimbeni.

Ngamachiza incwadi ingafunyanwa ukuba creatinine yenye ekuthiwa ekupheleni-iimveliso emzimbeni. Oku lithatyathwe creatine protein ukukhonza umthombo wamandla lokuba izihlunu. Xa creatine kwemisipha yikhompawundi ebizwa phosphocreatine. Ngenxa ukuncitshiswa creatine izihlunu inika amandla alo, waza yena uyazifohloza ukuya imveliso yokugqibela - creatinine, amanzi kunye phosphorus ngesikali. Ngoko ke umzimba creatinine. ingqondo yayo ixhomekeke kubungakanani mass kwezihlunu. Ngenxa yoko, amadoda creatinine igazi, izinga kwayo, usoloko ngaphezu koko ngabafazi.

Iimveliso ekupheleni inkqubo yokucolwa protein kwazona nge izintso kwi yokuchama. Le creatinine glomerulus evela igazi yahluzwa kwaye ocande tubules sezintso. Ngexesha ukusebenza njengeqhelekileyo kidney isusiwe ngokupheleleyo emzimbeni, oko kukuthi, kususwa egazini. On oku kusekelwe iimpawu zayo omnye iimvavanyo ezibalulekileyo kwezintso - isampula Rehberg. Ukusebenzisa ukuba uzimisele product glomerular. Kwaye ngenxa yokuba tubular eyaziwa GFR kubalwa sezintso le reabsorption. Kodwa makhe sithethe ngale nto kamva.

Creatinine kabani norm amadoda yi 0,044-0,106 mmol / l, kunye nabafazi - 0.44-0,88 mmol / L ukunyuka kakhulu izifo zezintso. A Inani kweelebhu iziphumo zophononongo ahleliweyo kwezinye iiyunithi - in micromoles. Ukuze ufake amanani creatinine micromoles mmol kufuneka iphindaphindwe 1000. Umzekelo, umlinganiselo abantu - 44-106 mmol / l.

creatinine Ukwanda - enye iimpawu eziphambili ukusilela kwezintso. Oku kungenxa yokuba i-ukuhluza kwi glomeruli sezintso kunciphisa kakhulu, ukwenzakala xa sezintso.

Noko ke, zokugula sezintso - hayi isizathu kuphela bendyebo zesi salathisi. Onke amazwe kunye nezifo apho kukho inkcazo ekhawulezayo phosphocreatine kwi izihlunu, nako ukwandisa creatinine egazini kumanani aphezulu. Oku kungenziwa okugunyaziswe umsebenzi dystrophy, hyperthyroidism, okune ngakwicala leeprothini, emzimbeni, acromegaly.

Xa iimeko ezibandakanya izihlunu izitshanguba zeethishu, creatinine anda, kakhulu. Umzekelo, olubanzi engabalulekanga iposi kunye nokwanda creatinine. isifo radiation, ukutsha, iyasilwa syndrome kwakhona ukuqhubeka kunye indyebo yalo.

Ukuthatha amayeza athile kwandisa creatinine. norm yayo makadlule ukuba isigulane ifumana sulfonamides, barbiturates, antibiotics of tetracycline kunye aminoglycoside series.

Ukwehla creatinine ngaphantsi kunesiqhelo akanaye ixabiso diagnostic, njengoko ukwanda. Kusenokuba ngenxa inani ngokwaneleyo kutya protein, indlala, ukukhathala. Ukwehla creatinine kwi wesithathu yokuqala yokukhulelwa, nokudumba, ascites. Inceda ukwehlisa creatinine elide ukusetyenziswa corticosteroids.

Bethengisa ukusilela kwezintso, njengoko sele kuchaziwe, oko kudla ilawulwa Reberga isampula.

Xa kusenziwa isigqibo ngokuqhuba creatinine, izinga apho egazini ukusilela kwezintso kube kakhulu ladlula nomchamo creatinine. Umchamo isampuli Rehberg kufuneka iqokelelwe emini, oko kunika iziphumo ezichanekileyo ngaphezu ukuba buthathwa ixesha elincinci. Kuyimfuneko ukuba umlinganiselo ngokuchanekileyo umthamo wayo. Ilabhoratri kusiwa encinci umthamo umchamo ngemihla, konke oko akuthethi ukuba awuthwale. Xa ukuqokelela umchamo kufuneka bakuphephe umthambo luthi yaye angadli protein eninzi. Igazi uya ungatyanga kusasa. Le mihla creatinine zinomgutyulo kwi umchamo ngokwesiqhelo ngokulinganayo 4,4-17,7 mmol / ngosuku.

Emva isigqibo igazi nomchamo creatinine, besazi isixa umchamo ngemihla, ubunzima yomguli kunye nobude (le yokugqibela isebenza ikakhulu abantwana) kwindawo indlela ekhethekileyo elabhoratri ubala ukuhluza glomerular uze - reabsorption tubular. Standards Funding for abadala ophakathi-abaneminyaka: ukuhluza glomerular amadoda - 82-140 ml / min, abafazi - 81-128 ml / min. UNorma reabsorption tubular - 95-99%. Kwimeko zokugxojwa umsebenzi kwezintso, ezi amaxabiso ziyancipha.