Cachexia - ntoni na? Cachexia in umhlaza

Cachexia - ntoni na? Cachexia, ngamanye amazwi, kwamanani komzimba - yinkqubo entsonkothileyo ephawuleka nelahleko ebonakalayo kobunzima bomzimba kunye ubuthathaka jikelele kwakunye utshintsho engqondweni. Oku kakhulu kuphele ezityebileyo carbohydrate oovimba, kunciphise protein kuyondelelaniswe, ngelixa sisenyusa catabolism yayo (hlula). Cachexia nako kwenzeka izifo oncological.

ukudinwa eziziiprayimari neziziisekondari

iintlobo ezimbini izifo cachexia - eziziprayimari nezizisekondari. luya Primary ukwabizwa ngokuba yebhinqa, kwaye aphakamileyo - nomqondiso.

● cachexia Primary okanye zithe zadala kwenzeka ngenxa inani elingonelanga izondlo, kwakunye njengesiphumo ukuphazamiseka zilandelayo: umothuko yobuchopho, ithumba okanye systemic sisilonda esidumbileyoesingaphakathi yebhinqa, hypophysitis samathambo, ntshikilelo elide, legazi (ukopha ngexesha iimpahla olindelwe), ukudla, Embolism ( kokungena amasuntswana angaphandle kweli ngoku igazi, ibangela semithambo occlusion), usuleleko ethile ezondeleyo.

● cachexia Secondary okanye iqala ibangelwa kwezifo ibangelwa zizinto ezifana gipoinsulinizm (insulin imibala), ukwanda Yindibanisela glucagon, malabsorption (malabsorption kwezondlo), imibala glucocorticoid, ukukhula neoplastic, somatostatin kwemfuneko.

oonobangela

isifo Cachexia kwenzeka ngenxa yezizathu eziliqela kunye zinto:
1. Imihla iyoluka ukungondleki kunye nendlala.
2. Izifo iphecana zesisu, ingakumbi kuvuleke iminxunya, kwakunye nesifo celiac, enterocolitis.
3. ukunxila elide kunye nesifo sokuphunza, isifo sephepha nezinye izifo ezosulelayo kunye neenkqubo suppuration ezigulo ezondeleyo.
4. anorexia Psychogenic.
5. Disorders ye nobubovu lengqula, insufficiency adrenal.
6. Izifo Ezingokuqandusela ezinxulumene kunye nezigulo metabolic.
7. Ukungaphumeleli Heart.
8. ithumba.
9. Ungachithi ebantwaneni.

Zeziphi iimpawu cachexia lubonakala? Ziziphi ezi mpawu?

symptomatology

Kukho eziliqela iimpawu, esibonakala yi cachexia. Ukuba esi sifo esenza imizimba yethu;
1. Isifo ubunzima ilahleko efikelela kwi-50% ubunzima bomzimba, kwaye kwiimeko kakhulu ngaphezulu kwe-50%.
2. emzimbeni.
3. Imisipha.
4. Ukukhubazeka.
5. zokulala.
6. izifo Ukwandisa soyiswa.
7. Ukuncipha kwii uxinzelelo lwegazi (uxinzelelo lwemithambo).
8. isikhumba Pale kunye flabby.
9. Ngaba vitamin izivuka, kunye nelahleko ngezinyo.
10. utshintsho Trophic kwiinwele nezikhonkwane.
11. Uphuhliso stomatitis.
12. zokuqhambuka kwesisu ngenxa yokuba ukuphazamiseka motility emathunjini.
13. Umxholo ephantsi protein yegazi, albumin, intsimbi, B12.
14. Amanina kwenzeka amenorrhea (ukumisa sexesheni).
15. Izifo zengqondo.

Cachexia kunye psyche

Ndingathanda ingqalelo ukuphazamiseka engqondweni cachexia. Baya kunokuzibonakalisa e nochuku, ukudandatheka kunye tearfulness ukuba kamnandi ayongena namdla, iinkcukacha ngokupheleleyo. Ndakuva exacerbation kwesi sifo apho unobangela cachexia ibonakala amentia / syndrome amential (nesiyezi, ebalasele ukungakwazi ukunikela ingqalelo, intshukumo nezidubedube kwesiphazamiso, kunye incoherence yokucinga kunye nentetho) okanye waphazamiseka (impambano apho umntu sikwimo rhoqo ixhala kunye nemincili ebona ukuba nemibono), psevdoparalich.

Cachexia in Oncology

cachexia ngumhlaza - njengesifo apho iyaqhubeka kunciphisa kwemisipha mass skeletal kunye zomzimba adipose kuphuhliso kwingxelo ithumba, ngokuzimeleyo isidlo. Luya ngokukhethekileyo awasiwisayo kwabo izigulane zibe ngumhlaza zesisu phecana okanye nemiphunga amalungu. Abantu abanjalo kulahlekelwa kangangoko 80% ubunzima bomzimba, ekhokelela nokungakwazi.

Umhlaza njengonobangela cachexia

Cachexia in umhlaza kunokwenzeka. Unobangela cachexia inokuba ithumba. Ngenxa yamathumba ukutya iba Nedlac, ukunyenyisa kuyo. Ithumba kufuneka substrates, ezinako ukukulumkisela ukuqinisekisa ukukhula kunye nophuhliso. Ngoko ke akukho mfihlakalo ukuba umhlaza cachexia nefuthe lokunxila kwi izicwili esempilweni amalungu, ukutshintsha ubume babo kwaye ibangele kakuhle.

Xa ukuyilwa yamathumba kwi isixa esikhulu lactic acid na kwesibindi eyonakeleyo. Ukuze bunjani yoxinaniso lactic acid, umzimba uqalisa ukusebenzisa iswekile egazini, yaye ngokufuthi abakwazi ukwenza umonakalo.

Xa cancer cachexia waphawula:
- ukuhla ezinkulu ubunzima kunye buthathaka;
- iphula kweenkqubo ukuzeyisa;
- ukuncitshiswa plasma cholesterol;
- uphuhliso zizifo ngenxa olwaphula okukwazi kumaza humoral;
- dysphagia (ubunzima ukuginya);
- ukugabha, urhudo;
- ukwanda kwemfuno amandla;
- antidiuresis kwaye, ngenxa yoko, hyponatremia;
- hypercalcemia;
- ukudumba;
- ukwanda glucocorticoids igazi;
- kwezinye iimeko, ingqondo kunye isiqaqa.

Imiphumo zomhlaza cachexia

Umhlaza cachexia kuyingozi kakhulu. Ukwanda igazi glucocorticoid isebenze iinkqubo gluconeogenesis (glucose amagama) esibindini kunye izihlunu zomzimba, kwandisa yokuwa iiprothini namafutha. Ngenxa amanani glucose ngokuthi iiseli umhlaza iphuhlisa hypoglycemia (eliphantsi iswekile yegazi). Kule mvelaphi (ezinokuthi zongezwe ntshikilelo), amadlala ezidalwe ngokubonakalayo ukuvelisa hormone mali agqithise leyo ekhokelela ukunxila kunye hypoxia hemic (ukuncipha umahluko arteriovenous oksijini ithambeka). ukungaqheleki Homeostatic kwenzeka. Konke oku kunokukhokelela ekufeni.

unyango cachexia

Uninzi unyango kwezigulane cachexia lwenziwa kwizibhedlele okanye kwiiklinikhi. Olona nyango kuhlanganisa unyango yokulahla neoplasms. Macingo namandla nokufunyanwa, nto leyo kuzuzwa ekwandiseni umzimba kunye neevithamini, iziqalelo umkhondo, amafutha kunye neeproteni. Ukulungiselela le njongo zingasetyenziswa ukutya lula ukutya. Basebenzisa iziyobisi ezifana: a anikezela ngezakhi kuba unyango lwe hypovitaminosis, enzyme ukuphucula ekugayeni. Ukutya yaziswa ngeendlela ezimbini: enteral (xa engena wokugaya) kunye parenteral (ukutya bayaphoswa lokugaya). indlela Parenteral isetyenziselwa ukususa isigulana bekwimo nzima (afe isiqaqa) kwi kunyango imihlaza kunye, emva kwabo, usulelo abangondlekanga kakhulu, kakhulu, ukuginya iingxaki. Salawulwa iswekile, iivithamini, imixube acid acid, electrolytes, hydrolysates iiproteins (parenterally alawulwa). Kwakhona, xa kusenziwa usebenzisa izixhobo ukwandisa khulise. Ukuba isigulane unesifo ukwetyisa kakuhle ukutya kunye nokufunxwa yayo, kusetyenziswa unyango amachiza polyenzyme (iziyobisi "Pancreatin", "emisitho" iziyobisi).
Ukuthintela ukuhlanza, ukumisela njengendlela "Delta-9-tetrahydrocannabinol". Oku kuyaphumelela nasemva ichemotherapy. Cannabinoids eziqulathwe kule ukulungiselela, ukuvuselela ukutya, kwaye, ngokulandelelana, kunye ukutyeba. Ukuncipha komzimba singamiswa kusetyenziswa ioli intlanzi, ngoko ke iphinde ibe yinxalenye unyango lwezifo ezifana, ezifana cachexia.

Unyango kunye namayeza.
Ukuphelisa ukusetyenziswa cachexia imithi:
1) "carboxylase" - inceda bunjani ubunzima, kunciphisa intlungu yaye lixhasa iinkqubo zomzimba. Iziphumo ebezingalindelekanga - komzimba. asinakusetyenziswa kuyo, ukuba ephilayo kuba sengozini licandelo ubuncinane enye.
2) "Megeys" okanye "megestrol acetate" - kukhuthaza ukwanda kobunzima kwezihlunu kunye namanqatha. Yinto ingasetyenziswa xa kukho uvakalelo amacandelo ichiza, abantu abangaphantsi kweminyaka eli-18 ubudala, ngethuba lokukhulelwa nokuncancisa.
Xa ukubakhona kwezifo ezosulelayo ziquka unyango unyango antibacterial. Ukuba kuyimfuneko, faka anaboliticheskie iihomoni. Kwiimeko ukuphazamiseka psychogenic ababandakanyekayo unyango lwe kwengqondo.
Siyathemba siye uphendule umbuzo wakho "Cachexia - oko kukuthi, ukuchaza alwe njani."