Antiulcer 'Omez' iziyobisi, kubonakala ukuba ukusetyenziswa, imiphumela emibi

Antiulcer medicament "Omez" kokwabo iqela inhibitor Iziyobisi. into esbnzyo - abangabancedani omeprazole - disodium edetate kunye sodium hayidroksayidi. Indlela yokusebenza ye omeprazole isekelwe phezu evalela i secretion of zehydrochloric acid kwinqanaba lokugqibela kwaye, ngenxa yoko, ukuncitshiswa acid. Njengoko omeprazole prodrug luvuliwe kwi esiswini acid esiphakathi. Kwisithuba kweeyure ezingengaphi emva kokuthatha 20 g yale arhente kubaguli isiphumo antisecretory siqala ukuvela, kwaye iqhubeka yonke imihla. Enye reception kwanele ukuba kwingcinezelo ekhawulezayo mihla le secretion esiswini, unyango layo eliphezulu results ngomhla 4.

Le omeprazole into esebenzayo ngohlobo granules, ngoko nokufunxwa yayo kwenzeka kuphela emathunjini kunye ubuninzi iyure enye ambona xi eliphezulu plasma yegazi medicament "Omez". amanqaku Isishwankathelo ku bioavailability bakhe phezulu kakhulu ka-40%. Uninzi ichiza kwazona kwi umchamo (80%), abanye - in inyongo (20%). Ipateni ezahlukeneyo pharmacokinetics kwi abadala, kukho ukuhla e imvume beziyobisi kwiziko bioavailability ukwanda.

Xa ekuxilongweni isigulana lwesifo isilonda Peptic, kucingwa ukuba indlela ephumelelayo yamalungiselelo "Omez" ezibonisa zokusetyenziswa namayeza akhuthazwayo kwi unyango izilonda esiswini kunye duodenal, kwakunye nokuthintela likakade. Xa isigulo enjalo aphela rhoqo ilawulwa ichiza ngomlomo ayiwenzi, kwaye ngohlobo ukumnika emthanjeni xa isixa-40 mg.

Kukho izifo apho idosi yemihla ngemihla iza kwandiswa "Omez" iziyobisi, kubonakala ukuba ukusetyenziswa kwiimeko ezinjalo ziqulathe isigulo giparsekretornyh ithi, ingakumbi Zollinger-Ellison syndrome. Ithamo yokuqupha le ezisemthethweni zoxilongo-60 mg, umntu ngamnye zithelekiswe isigulane ngasinye, yaye ngamanye amaxesha ixabiso eliphezulu ifikelela ukuthathwa ngemihla ka-120 mg. Kwiimeko ezinjalo, kufuneka yahlulwe infusions eziliqela ngosuku.

Xa umthamo we-40 mg, kwaye ngokufanayo iiyure ezi-2 phambi kokuba ulawulo arhente iintlungu ezilawulwa "Omez" ezibonisa ezibandakanya ukusetyenziswa mendelson engqondweni. Oko kukuthi, irejimeni idosi kucingwa kangangoko lokuthintela uthintelo kokungena bume acid esiswini kwi yomoya ngexesha utyando.

Ishedyuli ngayinye ngokufumana medicament "Omez" ebonisa ukuba isicelo ungaquka iSifo zilandelayo:

- reflux esophagitis;

- NSAID gastropathy.

Ngononophelo zinxulumene yokwamkela ichiza ngenxa yeziphumo ebezingalindelekanga. ukubonakala kwazo ziinkqubo umzimba ethile. Kwinkqubo hematopoietic, kukho iziphumo ezingalindelekanga ngohlobo leukopenia, pancytopenia, thrombocytopenia kunye agranulocytosis.

Inkqubo sokugaya idla iphendula ichiza "Omez" imbonakalo ukuqhina okanye isifo sorhudo, flatulence, isicaphucaphu nokugabha, nokuphazamiseka incasa. Xa insufficiency kakhulu hepatic wambi kubangelwa hepatitis (senyongo ngokunjalo).

CNS bavame uziva elingalunganga nesiyezi lolwamkelo esikolweni "Omez" ichiza babonakaliswa, badandatheke yaye akhawuleze ukucaphuka. Ukuba ukusebenzisa eli chiza xa isigulane lwandulelwe sisifo esibi isibindi, kusenokubakho kubekho Encephalopathy.

Ayifane bephawula ukusabela dermatological kwaye komzimba kunye ekubonakalisweni ezahlukeneyo.

Abstract "Omez" uye Izimo eziliqela. Guide ulumkisa ukusilela unyango ngexa lokukhulelwa, lokwaphusa kunye ebuntwaneni, ngoko ke kufuneka sithathe ichiza kubantu abane hypersensitivity ukuya omeprazole kweziyobisi esebenzayo. Iziyobisi libanda, kusetyenziswa unyango kwangumqondiso, ihaemodialysis kule meko kakuhle.

akufuneki ibe ukugcina olu nyango "Omez" Kwiminyaka engaphezu kwama-2 kwindawo epholileyo, kude ebantwaneni.