Analogs "Verapamil", imiyalelo ukwenzela ukusetyenziswa kweziyobisi kunye nohlolo

Heart ngokuba abantu lelona candelo ibalulekileyo. Ngoko ke, kufuneka uthathe unonophelo kakuhle kuye. Pharmacologists yayivelisa iintlobo ngeentlobo iziyobisi kugcinwe ukusebenza kwentliziyo. Enye yazo ichiza "Verapamil". Oku ezimiselwe ukunyhashwa yegazi, umfutho wegazi. Cinga yintoni isiyobisi oko sisebenzayo naziphi ezimbi. Yaye yintoni na analogue le "Verapamil"?

kunikezelo

Ichiza ifumaneka Iifom balawule ezininzi:

• tablets (40 mg, 80 mg);
• isisombululo / ku (2 ml / 5 mg);
• macwecwe emxholweni-ukukhululwa (240 mg).

Ukubunjwa ichiza

Kanye nucleoside ezininzi "Verapamil", ichiza sisixhobo egqwesileyo unyango arrhythmias inhliziyo. Olu phawu ibangwa iziyobisi olusisiseko medicament. Eyona nto elikhutheleyo ichiza verapamil hydrochloride.

Ngaphezulu iqulathe ezininzi kwezinto abangabancedani medicament:

• calcium phosphate dibasic;
• talc lihlanjululwe;
• wemagniziyam stearate;
• gelatin;
• methylcellulose hydroxypropyl;
• butylhydroxyanisole;
• indigo;
• methylparaben;
• starch;
• titanium dioxide.

Ngokuqhelekileyo, analogs "Verapamil" equlethe isithako enye esebenzayo, izithako ezongezelelweyo zahlukile.

imiphumela kwemithi

Xa iziyobisi "Verapamil hydrochloride" umyalelo ibonisa ukuba ichiza engena iqela blocker calcium channel.

Le medicament luphawulwa mihlaba ilandelayo:

• antiarrhythmic;
• antianginal;
• umfutho.

Xa abantu, lenza imisebenzi ezininzi:

1. Oku kunciphisa imfuno intliziyo oksijini.
2. Iphucula neempahla ivaleke.
3. Kunciphisa inani zisaphila.
4. Inceda ukwehlisa contractility engabalulekanga.
5. Oku kunciphisa ithoni izihlunu agudileyo kwemithambo.
6. Kuphucula flow kwegazi sentliziyo.
7. Umsebenzi wokufumana kwezithandani of sinus node ukuzenzekela.
8. Lingancipha AV-Uhanjiso.

Kuyinto ngenxa koku amayeza, oogqirha ukumisela amayeza 'verapamil' izigulane. Analogs beziyobisi ube neziphumo ezifanayo emzimbeni. Kodwa ithatha indawo yokuqala yedwa ayikhuthazwa.

Ubungqina obubonakalayo buxela ukuba

Xa ukunyhashwa nokusebenza kwenkqubo sentliziyo icebisa ukuba ukusetyenziswa kweziyobisi "Verapamil" umyalelo manual. Analogs le mali badla olumiselweyo ezimbi efanayo. Noko ke, oogqirha abaninzi bakhetha ziquka unyango na iyeza yokuqala.

Eli yeza lisetyenziselwa iinjongo amayeza. Oku kusetyenziselwa ukuba prophylaxis of ezimbi iziyobisi "Verapamil".

Iimpawu zibonisa ukuba ukusetyenziswa:

• angina (esitalini, oguquguqukayo);
• Isingqisho intliziyo engaqhelekanga;
• arrhythmias supraventricular;
• angina Prinzmetal ;
• enomoya atrial, fibrillation atrial;
• angina umehluko;
• tachycardia paroxysmal supraventricular;
• lwegazi.

Kodwa kufuneka wakhumbula ukuba naziphi na amayeza kuchaphazela umzimba ngamnye. Ngoko ke mabaqeshe a self-iyeza akuyomfuneko "Verapamil". Ubungqina obubonakalayo buxela ukuba zisetyenziswe - oku isikhokelo kwisenzo. Yabela amayeza ukuba ugqirha.

Izimo

Kuyanconywa ukuba ufunde ekuqaleni imiyalelo ichiza "Verapamil hydrochloride". Analogs kunye neendlela lokuqala Izimo. Yiyo loo nto akukho nasinye amayeza kufuneka ingasetyenziswa yedwa.

Cinga phantsi kwaziphi iimeko ezimbi zesixhobo kungabangela ukwenzakalisa umntu.

Eyona Izimo luphambili ukusetyenziswa kweziyobisi zezi:

• uvakalelo oluphezulu ze isigulane amacandelo eziqulathwe ekulungisweni;
• ukusilela intliziyo, aqukuqela ifomu ezingapheliyo, inyathelo 2b-3;
• mothuko cardiogenic (umnyinyiva yimeko okubangelwa arrhythmia);
• iposi engabalulekanga;
• syndrome sinus ogulayo;
• syndromes: Morgagni-Adams-Stokes, Wolff-Parkinson-White syndrome;
• AV-block 2 no-3 degrees;
• ukukhulelwa (1 ezintathu);
• ukusilela zentliziyo uhlobo oyingozi;
• zisanyisa;
• ibloko sinoatrial ;
• Ulawulo efakwa ibeta-blocker;
• bradycardia.

Ukongeza, ichiza ayenzelwanga ukuba abantwana abangaphantsi kweminyaka eli-18 ubudala.

Xa iyeza kufuneka wenziwe ngocoselelo olukhulu?

Kwezinye ezimbi, ugqirha unakho ukumisela amayeza. Noko ke, indlela yakhe ifuna uyiqwalasela kakuhle imeko yesigulane. Kwimeko iziphumo ezibi ugqirha ngoko nangoko endaweni iipilisi "Verapamil". Analogs eziya Kucetyiswa ukuba isigulane ukuba ukunika unyango kuyimfuneko, kwaye musani ukubacaphukisa izenzakalo ezingafunekiyo.

Ngokutsho imiyalelo kunye ukusetyenziswa olukhulu ngononophelo kuthetha ezimbi zilandelayo:

• ukusilela intliziyo, elibaleka ifomu ezondeleyo (1, iqondo 2);
• bradycardia;
• AV-ukuvimba (I degree kuphela);
• hypotension ;
• wavakalisa yokuphazamiseka ekusebenzeni esibindini.

Izikali tablet kuthetha

Kuyanconywa ukuba uthathe iipilisi ngexesha izidlo okanye ngoko nangoko emva kokutya. ipilisi nganye kufuneka makaginywe ngamanzi.

Ngokutsho imiyalelo, izigulane ezithatha ichiza "Verapamil" kufuneka zilandele ngqo le migaqo ilandelayo:

1. Ukuze amayeza angina kunye nothintelo arrhythmia kuthathwa ukuya ku-4 kathathu ngemini mg 80.
2. Ukuba izinga ekhethiweyo engazisi yona le isiphumo enyangayo ezinqwenelekayo, ugqirha uyakukumisela isigulane umthamo omkhulu. Kulo mzekelo, ukusetyenziswa mg 160.
3. Kubalulekile ukukhumbula ukuba izinga yonke imihla eli chiza yi-480 mg.
4. Ukuba isigulane iye kakuhle ukusebenza kwesibindi kunye zinomgutyulo olucothayo kakhulu amayeza, unyango uqalwe nge idosi esezantsi. Ngoko ke, lo idosi yemihla ngemihla ngu 120 mg.

isisombululo application

Olu hlobo ichiza ilawulwa zamathontsana kuphela. Noko ke, kule meko, nangona ichiza efanelekileyo ngokupheleleyo "Verapamil" izinto ezibonisa ukuba ukusetyenziswa yokuntlokothiswa kufuneka ukuba kulawulwe.

Ewiliko ke kancinci zifakwa. Kulo mzekelo, isigulane basoko belwakhele umkhanya cardiogram, izinga lentliziyo kunye noxinzelelo lwegazi.

Kwimeko ezimbi paroxysmal in unesifo lobunzima nomonde elawulwa 5-10 mg iziyobisi. Phakathi kangangesiqingatha seyure imeko yesigulane ngcono kakhulu. Ukuba isiphumo akwenziwanga waphawula, le nkqubo iphindiwe.

imiphumela emibi

Kufuneka kuthathwe kuphela ngokumiselwa kunye umthamo ichiza eyabelwe "Verapamil". Ukuphonononga ebonisa: Nakuphi na ukutenxa kule mithetho kunokubangela ngayo ezingafunekiyo.

Eli chiza iziphumo ebezingalindelekanga kulandelayo:

1. Intliziyo kunye nempahla. Kusenokubakho bradycardia, AV-block, hypotension. Ezinye izigulane zifumana anozizi ebusweni. Xa ngeedosi eziphezulu ukuze aphuhlise iimpawu ukusilela kwentliziyo.
2. CNS. ukudinwa Ukwanda, ukuba nochuku luvo, kuvela intloko. Ngamanye amaxesha abantu baba silale, ukuba nesiyezi.
3. Le nkqubo yokwetyisa. Okungakanani isicaphucaphu, ukugabha, nokuqunjelwa. Kwezinye iimeko, bekukho ukwanda enzyme zesibindi.
4. kubonakaliswa negazi. ngayo kunokwenzeka iziyobisi ezifana ukurhawuzelela, irhashalala.

Ngoko ke kubalulekile ukwazi ukuba ezi ziphumo bezingalindelekanga kukhokelela ichiza 'verapamil' yesikhokelo. Izimvo izigulane osebenzisa imithi ngugqirha ngokutsho kohlelo, zibonisa ukuba iziganeko ezinjalo waphawula kunqabile kakhulu.

analogue iyeza

Pharmacology liqulunqe izixhobo ezininzi ukuba ungakwazi esikhundleni isiyobisi yokuqala. Noko ke, balelwa ngqo ukukhetha analogue "Verapamil" ngokuzimeleyo.

Ukuba ngaba wehlelwa iimeko ezithile (umzekelo, iziphumo ebezingalindelekanga ngathi), kwaye kufuneka ukufumana enye indlela, qiniseka ukuba ubuze ugqirha wakho. Eli cebiso elula uya kusindisa kwimiphumo unyango engafanelekanga.

Ngoko ke, cinga oko ichiza "Verapamil" ntonye, ezilingana:

• "Verakard".
• "Verapamil Sopharma".
• "Vero verapamil."
• "Isoptin".
• "Verapamil Mival".
• "Verogalid EP".
• "Isoptin SR 240".
• "Verapamil Eskom."
• "Lekoptin".
• "Verapamil ratiopharm".
• "Kaveri".
• "Verapamil kuliphi."
• "Finoptinum".

oyi

Ngexesha amayeza "Verapamil" kufuneka ingqalelo oku kulandelayo:

1. Zonke izigulane kufuneka esweni umsebenzi sentliziyo kunye neenkqubo zemiphunga. Qiniseka ukuba babeke iliso kwinqanaba glucose kunye electrolytes egazini, umchamo umthamo.
2. Ukusetyenziswa 6 g beziyobisi kungabangela ukulahlekelwa osezingqondweni, lwegazi, sinus bradycardia, asystole. Kwiimeko ezinjalo, isigulana kufuna unyango nomqondiso.
3. Ukudityaniswa kwamaxwebhu medicament kunye iintlungu inhalation, antiarrhythmics, β-blocker kukhokelela ekwandeni ukusebenza cardiotoxic.
4. iziyobisi umfutho kunye womchamo nokukhuthaza ifuthe iqinile olufanelekileyo lwechiza.
5. Phenobarbital namayeza "rifampicin" buthathaka ukusebenza ichiza "Verapamil".
6. Iziyobisi "Lithium" yaye "carbamazepine", lo gama ukusebenzisa indlela ngasentla, kwandisa umngcipheko ekubonakalisweni neurotoxic.
7. Ngenxa indibanisela iziyobisi "Verapamil" yaye "digoxin" kufuneka ilawulwe isiqulatho egazini kwichiza yokugqibela. Ekubeni emngciphekweni omkhulu ukunxila amqumbise.
8. Le medicament njengoko isetyenziswa ngokudityaniswa kunye relaxants kwezihlunu kunokwandisa ifuthe yokugqibela.
9. Amalungiselelo "Ranitidine", "cimetidine 'isandla ekukhuliseni yoxinaniso wenkqu iziyobisi esebenzayo" Verapamil "ngegazi.
10. Indibaniso oku kuthetha kunye medicament "Acetylsalicylic acid 'inokukhokelela ukopha.
11. Le into esebenzayo na onako ukuma ngaphandle ubisi lwebele. Ngoko ke kunqweneleka kakhulu ukuba ukusebenzisa isixhobo ngexesha zisanyisa.
12. Abafazi abakhulelweyo emiselweyo amayeza kuphela xa ichiza inzuzo ukuya unina iphezulu kakhulu amathuba ubomi kunye nempilo yosana.

Izimvo kulungiselelwa

Njengayo nayiphi na amayeza, ezinye izigulane esi sixhobo kubonwa amayeza asindisa ubomi ephelisa iimpawu ezingemnandi. Kodwa ezinye izigulane bagxeka iziyobisi, ebonisa ukubonakalalisa basabele ezibi.

Nakuba kunjalo, phantse bonke abantu ngokuthatha amayeza, kodwa bayavisisana kule nto: inceda ngenene neengxaki ngentliziyo okanye amayeza uxinzelelo "Verapamil". Baqinisekiswa kugxininiswa ngokukodwa uncedo ichiza.

Oku uyakwazi ziyakwehlisa ngokubonakalayo izehlo arrhythmias. Iyeza linceda ngokupheleleyo igazi umfutho xa lwegazi. iziphumo ezilungileyo ezibonwa kwizigulane uxilongwe angina. Abantu abafumana yesi ebuhlungu wegazi, qaphela ukuba ngenxa yokuba bakwazi ukubuyela kubomi bemvelo, normalizing ubume bawo medicament.

Kodwa phantse zonke izigulane ukuba ichiza bezisa imiphumo eyingenelo ukubonisa ukuba arhente sele lityunjiwe ugqirha.