Product "Lamivudine": imiyalelo ukusetyenziswa, inkcazo, ukwakhiwa kunye nohlolo

Namhlanje, abantu abaninzi ngakumbi uve uxilongo ezoyikekayo - HIV. Le ngezifo iye aqheleka kakhulu kule minyaka imbalwa idlulileyo. unyango lwe-antiretroviral efunekayo ngpahmbi ukwandisa ubomi ezi izigulane. "Lamivudine" imiyalelo yokusebenzisa eziza kuxoxwa ngazo iinkcukacha ngezantsi, yenye amachiza esetyenziswa ukunyanga indibanisela HIV.

inkcazo jikelele kunye nokwakheka

Thaca na amayeza antiviral kwaye isetyenziswa kunyango lwe-HIV. Kwiimeko ezininzi, ichiza isetyenziswa ngendlela tablet emhlophe. Ilungu ibalulekileyo arhente yi lamivudine. Enye tablet iqulathe mg 100 okanye 300. Phakathi components ezinxulumene umntu enokuzichongela zezi: starch sodium glycolate, nemagnesium stearate, titanium dioxide, hypromellose, polyethylene ethers.

Amacwecwe ziveliswa iqokobhe. Drug ethengiswa iipakethe-10, 30 okanye 60 iipilisi.

Kwakhona, lo medicament yenziwa njenge sisombululo ngomlomo.

imiphumela kwemithi

Ukuba ufuna i "Lamivudine", imiyalelo zokusetyenziswa (inkcazo sele kucingwa) ibonisa ukuba isenzo sakhe, into ephambili ngokukhawuleza ingena ngalo inwebu kungena iseli kunye umzimba. Indlela abasabela ibonakala transkripazy inhibitor HIV, nto leyo abangaphangeliyo nophinda-phindo iiseli eziyingozi. Ichiza ubonakala umsebenzi ophezulu isantya abekho phantsi kwamanye amachiza.

Ukudibanisa kuthetha umsebenzi ubonakala phezulu kwesibindi B. Oko kukuthi, oko zifakwe kwi kwanonyango oluntsonkothileyo ezimbi zesibindi. Nakuba kunjalo, kufuneka zithathwe kuphela ngemvume kagqirha.

Njengoko into ilawulwa ngomlomo, ukufunxeka kwayo kwenzeka kwisiqwenga zesisu. inqanaba bioavailability koko ufikelela 86%. Ukuba uthathe amacwecwe kunye nokutya, khumbula ukuba kulo mzekelo, ixesha ukufikelela ukufumaneka liphezulu egazini plasma kwemali ukunyuka.

Lenza kunye nomchamo ngohlobo ingaguqukanga. Icandelo eziziintloko kancinane ukungena kwi ubisi lwebele. Uyacetyiswa ukuba ukuyeka nokuncancisa ngexesha unyango. Isiqingatha wobomi ichiza iiyure 3-5.

Iimpawu kunye Izimo

Ukuba ufuna ukuthenga "Lamivudine» (Lamivudinum), ukusetyenziswa kweziyobisi kunokwenzeka kwiimeko ezinjalo:

1. Ngexesha unyango lwe-HIV phakathi kwabantwana nabantu abadala.

2. wentsholongwane Hepatitis B (ifom ezingapheliyo).

Noko ke, asinguye wonk 'umntu ukuba athathe eli chiza. Ukuba isabelo "Lamivudine" yemiyalezo ulumkisa ezi Izimo zilandelayo:

• Ukumelana ichiza.

• ukugaywa olungafanelekanga lwemihlaba lactose.

• Abantwana ubudala okanye iqumrhu ubunzima ukukhanya. Musa ukunika ichiza umntwana ukuya kwiminyaka-3, kwakunye nezo ezinolwazi ubunzima khange kufikelelwe 14 kg.

• Kukho iingxaki kunye kungengokwentlambululo yendawo umsebenzi kwezintso (ngaphantsi kwe 30 ml / min yokususwa creatinine).

• Ixesha yokumitha nokondla umntwana.

Kufuneka balumke xa ukusetyenziswa kweziyobisi kwezi meko:

• A isigulane kwafunyaniswa kukho ukusilela kidney kakhulu.

• peripheral (peripheral) ngohlobo oyingozi okanye imbali.

• i-pancreatitis.

Features umthamo, imiyalelo ezizodwa, kwaye imithi

Yabela "Lamivudine" (imiyalelo ngokusebenzisa ichiza iqhotyoshelwe impahla nganye) na ugqirha kuphela osele enamava unyango lwe-HIV. ekudleni aluchaphazeli inyathelo beziyobisi. Share tablet lezabelo ayikho imfuneko. Kubhetele ukuba imginye ngomphefumlo, kodwa kulo mzekelo, lo kangangoko unako kuphunyezwa.

Ukuba kuyimfuneko ukuba ichiza "Lamivudine" umyalelo ncwadana inika ukusetyenziswa hlobo: abantwana emva kweminyaka emithathu yaye abadala abanobunzima ngaphezulu kwama-30 kg, imfuno basele 1 tablet (150 g), amaxesha 2 ngemini, okanye philisi 1 (300 mg), 1 ngosuku. Abantwana kwiminyaka emi-2 ukuya ku-12 eyabelwe 3 mg / ubunzima bomzimba kg kanye ngemini. Kungcono ukuphulaphula ukuze zikhanyise kwagqirha. Yingcali liya kuqesha idosi kakhulu kangangoko ngokusekelwe kuhlalutyo yakho, nobume bempilo kunye nesifo ubukhulu.

Njengoko sokubambisana, sinokuthi oku kulandelayo. Ngokomzekelo, xa kuququzelela-elawulwa with "zidovudine 'ixesha amanyathelo yokugqibela inyuswe. Kodwa "AZT" aluchaphazeli izinga zinomgutyulo "Lamivudine". Musa ukuthatha iyeza nodibaniso 'zalcitabine "" ddI "kunye sulfonamides le sengozini enkulu yokuba pancreatitis.

imiphumela emibi

Kodwa ngokucokisekileyo "Lamivudine", imiyalelo zokusetyenziswa (ixabiso ichiza 4,000 engange pack nganye, kwaye nangaphezulu.) Uthetha malunga neziphumo ebezingalindelekanga enjalo:

1. izifo zemiphunga Infectious.

2. A iqondo eliphezulu ukudinwa.

3. Ubuhlungu entloko.

4.-caphu, ukugabha, urhudo.

5. Ukwandisa xi enqanda hepatic.

6. Ukwehla imnyama.

Ngokuzimela ukwenza mindzulamiso iidosi akunakwenzeka. Kukho irejimeni ethile, leyo angawugqithi.

Analogs, ukubuyekeza, features imveliso yokugcina

Ukuba ngenxa yesizathu esithile ichiza a engavumelani nawe, ungasebenzisa i analogue ezichazwe ngasentla. kukho phakathi kwabo, "Amiviren", "Virola," "Zeffiks", "Epivir." Baye neziphumo ezifanayo.

Ubude bethuba lokusetyenziswa kwe ichiza iminyaka emi-3. Gcina izixhobo kufuneka kwindawo ekhuselweyo ukusuka ukungena reyi ukukhanya. Okulandelayo akumele amalahle izixhobo. Ngaphezu koko, kungakuhle ukuba ukususa ichiza ukusuka kwigumbi apho kukho izinga eliphezulu ukufuma.

Njengoko ngokuba ujongo, zahluke. Kwelinye icala, izigulane ingxelo ukusebenza kakuhle beziyobisi kumlo ochasene ne-HIV. Kwelinye icala, bethetha malunga nengozi ephezulu yeziphumo ebezingalindelekanga. Amaninzi ichiza Uxhokonxwa uyagabha, ukudinwa kakhulu. Njengoko zimelwe ngokuthi kudityaniswe nezinye izinto antiviral, ubunzulu reactions ezingafunekiyo nande. Ngoko kumiselwe ichiza, kwakunye ukulungisa umthamo wayo kufuneka ugqirha.

Ngoku unayo yonke ingcaciso malunga namayeza "Lamivudine". Imiyalelo yokusebenzisa, ixabiso, ncomo ngoku makwazeke kuwe. Hlala uphilile!