"Pomalidomid" (imnovid): oothixo ixabiso. Njengoko yongayo ukuthenga i "Imnovid"?

Pomalidomid - na ichiza elisetyenziswa isizukulwana esitsha anti-ithumba modulators omzimba. Le izinto anazo lo zikwazi ukunqanda stromal (baphuma) iiseli ezixhasa uphuhliso kunye nokukhula ezigula. Ukongeza, loo nto ibangela apoptosis (programmed ukufa kweeseli ezineziphene) nonyebeleziso ezilawulayo (ukukhula inyama).

Studies ababonise ukuba ngokusebenzisa pomalidomida 52% kuncitshiswa isantya progression and iminyaka yobomi kakhulu anda.

Uchaza into sele sivunyiwe kwi US ngenxa yonyango ezigula eliyinjubaqa ezininzi kwaye wabuyela kuzo. Apho iyafumaneka phantsi igama lorhwebo "Pomalist" njengoko yaziwa kwi-EU njenge "Imnovid".

Ndisenako ukuthenga phi iziyobisi zitshiphu equlethe pomalidomid

Ngaphambi kokuba aqhubeke nenkcazelo intshukumo pomalidomida, kufanele kuqatshelwe ukuba amachiza ezifunekayo unyango umhlaza, abiza imali eninzi. Ke ingxaki izigulane kukuba unyango sophazamiso akukho ndlela kodwa ukuhlawula kwikhosi yonke - kuyingxaki kakhulu. Ngoko ke, eMoscow phezu ichiza sokuthengisa aqulatha ixabiso pomalidomid ugcina malunga 819.000 engange.

Kule meko, uya kuza kubanceda kwisiza ezaziwayo-kakuhle www.onko24.com. Apha uyakwazi ukuthenga amachiza afana nalawo equlathe eyona nto efanayo esebenzayo - pomalidomid, ixabiso lazo ngexesha elifanayo liyakufikeleleka kakhulu ngakumbi. Kwaye oku ngenxa mgangathweni yokulungiselela, kunye nento yokuba inkampani edumileyo Indian evelisa oko, akukho mfuneko ukutyala imali kuphando, uphuhliso kunye neentengiso. Wathe- kuphela ilungelo ukuvelisa ichiza, echaza iindleko esezantsi kakhulu, kunye nokusebenza efanayo.

Umthamo ukulungiselela nomthamo

Pomalidomid kubonisiwe unyango lwezigulane eyi-18 okanye nangaphezulu, abo ngokuphawulekayo progression ezigula eliyinjubaqa ezininzi alandelayo izifundo ubuncinane 2 unyango kunye bortezomib kunye lenalidomide.

Faka isixhobo ngaphakathi, kunye dexamethasone, mg 4 kanye yonke imihla, iintsuku ezingama-21, emva koko kufuneka ikhefu iveki.

Ichiza kufuneka yenziwe kwi iiyure ezifanayo yonke imihla, nokuba amaxesha isidlo. Ukuhlafuna okanye kuzityumza uVitamin engenakwenzeka. Ukuba elinye inyathelo liphosiwe, ngoko akuyomfuneko ngosuku olulandelayo ukuba usele umthamo kabini.

Ngenxa ukuqhubela phambili unyango sifo sinqunyanyisiwe.

Izimo

Musa amisele iziyobisi eziqulathe pomalidomid, abantwana abangaphantsi kweminyaka eli-18 ubudala kunye nabasetyhini abakhulelweyo. Ibele ngexesha arhente unyango ebizwa kufuneka kupheliswa.

Imeko kwezigulane ongaboniyo kwezintso kwaye hepatic kufuneka ajongwe ngugqirha wakho mana yokusabela ezibi yokuqala.

effect side

(. "Imnovid", "Pomalist", njl) Xa ukuphatha amalungiselelo eziqulathe pomalidomid, ibinzana neziphumo ezibi zilandelayo kunokwenzeka kwizigulane:

• nokudinwa;
• kukuvela yintloko, isiyezi, kunye nokudideka;
• isicaphucaphu, ukugabha;
• ukulahleka emnyama;
• izifo zesisu ukusebenza;
• anaemia, thrombocytopenia;
• kukuvela amahlaba izihlunu kunye buhlungu amathambo;
• uphuhliso kwezifo ezosulelayo le iphecana eliphezulu wokuphefumla;
• angawokubhuda.