Testosterone undecanoate: uqeqesho, analogs kunye nohlolo

Testosterone undecanoate yi Ester umntu androgen zendalo, testosterone. Malunga koko, ukukhulula oko kwifomu isixhobo oko yaye isetyenziswa njani, sixelelwa kwinqaku thaca.

Kwakhona uya kufunda ukuba iimpawu, iziyobisi, ingaba unazo Izimo kunye neziphumo ebezingalindelekanga.

Ubume, incazelo kunye nokupakishwa

Testosterone undecanoate kuthengiswa ngeendlela ezahlukeneyo:

• njengezingxobo Gelatin eziphethe into esebenzayo. Bona zipakishwe namadyungudyungu kunye iibhokisana ngokulandelelana.
• I-oyile kunye isisombululo esicacileyo unomona bulubhelu lolawulo intramuscular. 1 ml yokulungiselela iqulethe 250 mg testosterone undecanoate. Njengoko izinto auxiliary asetyenziswa: benzoate benzyl neoli kukaCastor nyulu. Ichiza ithunyelwa iglasi amber etywiniweyo, apho ibekwe kwibhokisi yekhadibhodi isiphatho ampoule njo.

Pharmacology

Indlela ukufumana testosterone undecanoate? iingcali Guest ingxelo ukuba uhlobo esebenzayo loo ichiza ukhandwa cleavage chain ecaleni.

Testosterone ebizwa inkunzi hormone ngesondo, leyo lonke lwaseNtshona Koloni ziba umsebenzi eziphilayo okuyimfuneko ukuze kwakhiwe kunye nokugcinwa kwemisebenzi androgenic.

Yolungelelwaniso osisiqu lwenzeka kwi amasende kunye uthinte adrenal. Ngexesha Palsy, kwakunye nokubhala kwabantwana abaselula kunye ukufikisa lwesi sakhi kunegalelo ukuyilwa lweempawu iinkunzi kunye esini. Kamva, hormone androgenozavisimyh wathi inika imisebenzi yenkxaso kunye phenotype eyindoda.

secretion boyilo weli kukhokelela kuphuhliso okhawulezileyo. iimpawu zayo ziquka erectile kwekhono, isimo ukudakumba, sinciphise yobuntu, ukudinwa, parameter nganye, ukungabikho okanye uphuhliso zaneleyo lweempawu zesini eziziisekondari.

Kwakhona, le abameli oyindoda womelele kwandisa umngcipheko kwamathambo.

izakhiwo

Testosterone undecanoate yenziwa kukhuthaza inqanaba elingonelanga testosterone zemveli, kwakunye nasekunciphiseni iimpawu okhawulezileyo.

Indlela yokusebenza kweli chiza kungenxa le mihlaba ilandelayo:

• androgenic (luchaphazela epididymis, vesicles amadlozi, wendlala);
• protein-steroid (kuchaphazela ithambo, izihlunu, zezintso, inkqubo hematopoietic, isibindi).

Amadoda abaphethwe okhawulezileyo, testosterone undecanoate kunciphisa mass amafutha kunye nokunyuka umzimba ezinqinileyo. Oku kuthintela Kwakhona ilahleko kwaye ikhuthaza ukukhula esiqwini ithambo, kuphucula umsebenzi ngokwesondo kwaye nemiphumo emihle psychotropic.

Ubungqina obubonakalayo buxela

Ukuze oko ukusetyenziswa amalungiselelo testosterone undecanoate? Manual ithi kubantu besini ngokomelela ezo mali zisetyenziswa hormone therapy enokuphazamisa ukuba zibangelwa lesibini okanye primary imibala testosterone, kuquka post-kuthenwa syndrome, hypopituitarism, syndrome, ezidalwe namandla kwaye ezinye iindidi nenzalo, ezo zibangelwa ukuphazamiseka spermatogenesis, kunye climacteric ukuphazamiseka emadodeni (umz, kunciphise umsebenzi ngokwasemzimbeni nangokwasengqondweni, yobuntu).

Izini ukutshintsha ngesondo (ngabantu), eli chiza omiselwe masculinization.

Kwakhona testosterone undecanoate enokusetyenziselwa kwamathambo, nto leyo ebangelwe intswelo androgen.

Izimo

Testosterone undecanoate (ampoules kunye namacwecwe) kunye esalelweyo ukusebenzisa:

• androgenozavisimoy carcinoma le wendlala;
• hypercalcemia, nto leyo sikhatshwa ngamathumba amabi;
• androgenozavisimoy carcinoma incum kwi oyindoda womelele;
• hypersensitivity ukuba izinto isiseko okanye nayiphi na inxenye yale nkampani ichiza;
• imbali yamathumba zesibindi okanye mzuzu.

Kufuneka kuqatshelwe ukuba undecanoate testosterone ( "Nebido") akukho kubonisiwe abafazi.

Nangononophelo olukhulu kucetyiswa kwizigulane bubuthongo umoya syndrome kunye nabantwana elivisayo zabo.

Umthamo iipilisi

Iipilisi ezinyusa testosterone ngabantu, kufuneka zithathwe kuphela xa inkqubo ukutya. Kulo mzekelo, ukutya kufuneka lingaqulathi amafutha amaninzi. Kungenjalo, kukufakwa ichiza ngokusebenzisa inkqubo emithanjeni kuzo ukuba ziqhubele phambili.

Xa abafumana iipilisi ungatyanga yokufuduswa engephi.

Ukuba ichiza iye yanyulwa ngenjongo ukwandisa testosterone kumntu wesini ngokomelela, oko kumiselwe kabini ngemini.

Ukunyusa umgangatho androgens xa kukho umthamo amayeza esithathwe lilingane 120-160 mg yonke eminye imihla iiveki ezi-3.

Kuba imiphumo zicaca steroid, iingcali bacebisa ukusetyenziswa amathamo eziphakamileyo ichiza. Kule meko kuyimfuneko ukuthatha 240 mg beziyobisi ngemihla. Kufuneka kukhunjulwe ukuba idosi elolu hlobo isenokukhokelela ekubeni ngayo ezibi.

Zesicelo Iifomu injectable ye ichiza

Ukuqaliswa ichiza "Nebido" xa umthamo we-1 g testosterone undecanoate (okt 1 ampoule) ikhutshwa phandle kanye ngemini iiveki 10-15. kwizitofu ezifana frequency inika inkxaso ezaneleyo ukwenzela inqanaba hormone oko akayizisa cumulation.

Ichiza ilawulwa intramuscularly ngoko nangoko emva kokuvulwa ampoule. Iinaliti zenziwa kancinci. Ngelo xesha linye ubone ukuba ichiza asingeni isitya yegazi.

Phambi kokuba uqale unyango, kufuneka udibane nogqirha. Le yokugqibela uya kumisela isixa testosterone kwi serum.

Isithuba phakathi naliti lokuqala kufuneka ibe kwiiveki ezi-6.

Ekupheleni kwale uluhlu, khangela uyondelelwano lwee- testosterone egazini. Ukuba inqanaba le ngezantsi eziqhelekileyo, lekhefu phakathi izitofu kufuneka ukunciphisa.

Ukuba xi testosterone liphezulu, kufuneka ucinge ukwandisa lekhefu.

imiphumela emibi

Emva kokuthatha iipilisi ukusuka eyomeleleyo ukuze aphuhlise iziphumo ezingafunekiyo zilandelayo:

• abanengi rhoqo, uphuhliso ngokwesondo esebenzayo, ukwanda esini nomthinjana;
• sodium kunye nokugcinwa kwamanzi;
• ukwandisa yobuntu;
• oligospermia;
• priapism kunye nezinye iimpawu zovuselelo ngokwesondo;
• isicaphucaphu kunye nesiyezi.

Ngenaliti intramuscular beziyobisi waphawula ngabantu:

• ukwandisa umthamo, hypersensitivity;
• ukutyeba, hypercholesterolemia;
• kwanda, polycythemia;
• ukwanda kwinani erythrocytes, ukudandatheka;
• sokulibala, migraine, ixhala;
• ndlongondlongo, intloko ebuhlungu, ukuba nochuku;
• siwasebenzise, isiyezi, hypertension;
• iphika, ukuphelelwa umoya, sinusitis, sorhudo;
• irhashalala, arthralgia, amaqhakuvana maculopapular, neentlungu imilenze;
• kukudlathuka kweenwele oko, ukungakhululeki kwezihlunu, kome ulusu kunye t. d.

Price kunye analogue

Testosterone undecanoate kwi ekhemesti nga kuthengelwa 1000-1200 engange.

Analogue iyeza iziyobisi ezifana "Andriol", "Androkson" yaye "Virigen". Misela ukuba yeyiphi kwezi mali kufuneka isetyenziswe ngexesha unyango, yezandla ungakwazi kuphela abanezakhono ngokusekelwe axilongwe kunye nocazululo data.

Izimvo zabantu kwi amayeza

Testosterone undecanoate - ichiza leyo isoloko isetyenziswa nonyango hormone. abantu abaninzi ngokuthatha lo amayeza, uthethe ngayo kuphela kwicala ezintle. Bathi macwecwe testosterone lingaphantsi kwe-ziyobisi kodwa kwifom injectable olusebenzayo. Ngenxa yoko, izigulane ezininzi zama ukufumana indlela ku ampoules.

Nangona kukho amanye amadoda abathi ukuba iipilisi undecanoate testestorna zilunge ngaphezu inaliti. Ngaphezu koko, ukuba lula ngakumbi, njengoko ingahoywa nje kuphela ekhaya kodwa nasemsebenzini, ukuphumla njalo njalo.