Monocytic ehrlichiosis umntu: isifo kwaye afumane unyango

Monocytic ehrlichiosis umntu - oku sisifo enqabileyo esosulelayo esibangelwa bacterium yintsapho Ehrlich. Pathology ngazo ukunyuka okukhulu lobushushu emzimbeni, intloko ebuhlungu, iintlungu kwezihlunu (myalgia), kuthibaza, ukudinwa phaku, buthathaka. Symptomatology uyaqapheleka kwiiveki ezimbalwa emva kokuba usulelo lokuqala. Ngaphezu koko, kwiimeko ezininzi, ngenxa iimvavanyo laboratory kutyhilwa ukuncitshiswa kwenani zegazi kwi elijikeleza igazi (thrombocytopenia) kunye nokuhla in white legazi count (leucopenia), kunye nokwanda ezingaqhelekanga kumanqanaba enqanda ezithile kwesibindi (transaminase hepatic). Kwezinye iimeko, iimpawu inkqubela kwaye zibonakaliswa isicaphucaphu, ukugabha, urhudo, ukwehla kobunzima, ilahleko yokuqhelaniswa nezifundo emajukujukwini. Ukuba isigulane uchonge ehrlichiosis monocytic yabantu, unyango kufuneka ulandele ngoko nangoko emva sifo, kuba ukungabi sisifo ezaneleyo unyango kukhokelela kubunzima eziyingozi ezifana ukusilela kwezintso okanye zemiphunga. Babethwele izifo amangolwane.

Lweempawu

Monocytic umntu ehrlichiosis, iimpawu ngawo kulula ukuba kubhidaniswe iimpawu zezinye izifo ezosulelayo, waza wafunyanwa xa zithelekiswa kutshanje uphando. Ngokuqhelekileyo, le ngezifo babonakaliswa malunga neeveki ezintathu emva kokuba elunyiwe, uphawu - Ehrlich iintsholongwane othwala usapho. Ekuqaleni, izigulana iimpawu ezithile zosulelo, kuquka ukunyuka okukhulu lobushushu emzimbeni kunye ubuthathaka jikelele. Kwezinye iimeko, irhashalala ulusu wongezwa iimpawu ezinjalo. Xa izifo kakhulu isigulane ulahlekelwa wokutya, ukunciphisa umzimba ngok usemngciphekweni Ukuba NeAnorexia sifo. Maxa wambi, kukho kwakhona iimpawu ehrlichiosis anqabe - ezifana ukukhohlela, urhudo, umqala obuhlungu (pharyngitis), kunye neentlungu esiswini.

Kwiimeko ezininzi, xa ehrlichiosis yabantu monocytic kurhanelwa, uxilongo ibandakanya iimvavanyo zegazi. Iziphumo zezi mviwo (indibanisela leuko- kunye thrombocytopenia ngaxeshanye ephakamileyo okungaqhelekanga enqanda kwesibindi) avumele isigulane ukubeka uxilongo echanekileyo. Kwezinye iimeko, isigulane uphethwe kwesibindi ukudumba (hepatitis).

Xa engekho unyango eyaneleyo ukuphuhlisa kakhulu monocytic ehrlichiosis umntu. Iimpawu zesi sifo kweli nqanaba kwahluka ekubonakalisweni umgangatho yosulelo kwaye luboniswe kule nesenzeko zilandelayo kwaye uthi:

• ukuphelelwa umoya (dyspnea, dyspnea);
• iingxaki igazi ekunqandeni (coagulopathy) enokukhokelela ukopha kwisiqwenga zesisu;
• zizigulo zemithambo ngenxa Cerebral spinal usulelo (inkqubo luvo).

Ukuba inqanaba lesi sifo itshayelwe inkqubo luvo, isigulane unesifo "ehrlichiosis monocytic zabantu" ibhaqwe izihlunu engaqhelekanga (ithumba) apha ebuchotsheni. Ukongezelela, kwezinye iimeko eziphuhliswe meningitis - ukudumba inwebu inwebu zikhusela ingqondo kunye umnqonqo. fluid fluid kwakhona kuchatshazelwa yi-HIV.

kubonakaliswa lwezempilo

Iimpawu luvo lwe sifo zibandakanya:

• nokudideka;
• uvakalelo engaqhelekanga ekukhanyeni (photophobia);
• ukuqina entanyeni;
• iziqephu yomsebenzi zombane engalawulekiyo ebuchotsheni (uhlaselwe);
• isiqaqa.
• Kwiimeko ezinqabe kakhulu, kukho:
• reactions obukhulu ngokugqithiseleyo reflex (hyperreflexia);
• incoordination yeentshukumo ngokuzithandela (Ataxia);
• ukulahleka kwenxalenye ubuchule lwemoto imisipha yobuso ngenxa umonakalo elinye (okanye ngaphezulu) kwezi zibini ezilishumi luvo ezinxulumene ebuchotsheni (ebinabo luvo cranial).

ehrlichiosis Monocytic kunye granulocytic ianaplasmosis oluntu kungekho unyango lobungcali kwezifo ubomi emngciphekweni.

izizathu

Zonke iintlobo le ngezifo zihlalutywe ezibangelwa iintsholongwane ukubayinxalenye usapho Ehrlich. Lwegciwane ehrlichiosis monocytic umntu kuthathwa ezimbi-Igram.

Kukholelwa ukuba oyena nobangela usulelo - uphawu ezilumayo. Ezinye zezi zinambuzane abathwali kwamagciwane.

Kanye emzimbeni ngegazi, Ehrlichia ukusasaza ngalo igazi kunye nempahla emithanjeni. Nkovu - ulwelo yomzimba ephethe iiseli enzelwe ukulwa nezifo ezosulelayo. Iibhaktheriya zibetheleleke kwezinye iiseli (monocytes kunye macrophage), apho badlala indima ebaluleke kakhulu zokunyamekela yokusebenza ezinzileyo kwamajoni omzimba. Ezi seli andisa neentsholongwane alungiswa (inkqubo ekuthiwa phagocytosis), kuquka iintsholongwane kunye nezinye izinto kwamanye amazwe. Noko ke, Ehrlichia ukungena nzulu wokhuselo omzimba iqala ukukhula kwi vacuoles - nemingxuma, engqongwe inwebu. Esi sifo sichaphazela kuphela monocytes kunye macrophage egazini, kodwa iindidi ezithile izicwili komzimba (kubandakanywa lomongo wethambo, iindawo nkovu, isibindi, udakada, izintso, imiphunga kunye ulwelo spinal).

Differentsiatsialnaya ukugula: ianaplasmosis granulocytic

Iimpawu zesi usulelo kube lula kubhidaniswe iimpawu ze nezinye izinto ezimbi. Umahluko uphethwe kakhulu rhoqo ukuba ehrlichiosis monocytic kunye ianaplasmosis granulocytic yabantu.

Ngokungafaniyo Mach, ianaplasmosis granulocytic ezibangelwa iintsholongwane kunye negama elifanelekileyo Anaplasma. Silwanyana olwenziwe ngeetikhi, ichaphazela iiseli granular ezithile ezimhlophe zegazi - granulocytes neutrophilic. Ezi seli baxakeke kwinkqubo phagocytosis kwaye idla uxanduva kutshatyalaliswe iintsholongwane eziyingozi. Xa zingenwe Anaplasma iimpawu eziye ngokuqhelekileyo wabonakalaliswa ngeveki emva uphawu inyeke - iintsholongwane umthuthi. Phantse ngamaxesha onke, isigulana unesifo ifiva, kuthibaza, iintlungu kwezihlunu (myalgia), ubuthathaka jikelele, ukudinwa, intloko ebuhlungu. Maxa wambi kukho kwakhona iqela ukukhohlela, ukugabha, kunye / okanye nokudideka. Ngaphezu koko, granulocytic ianaplasmosis efana usuleleko ezifana ehrlichiosis monocytic zabantu, ngenxa yokuba iziphumo zovavanyo yegazi lubonise ukwanda efanayo enqanda ezithile kwesibindi (transaminase hepatic). Kuhlala kungafunyaniswa kwaye anaemia okubangelwa kukuvela kwemeko ukuhla ezingaqhelekanga kwinqanaba iiseli ezibomvu zegazi egazini elijikeleza. Xa engekho unyango olufanelekileyo lwenzeka emngciphekweni wokuhlaselwa ukusilela kwezintso. Kwi-US, amatyala, ianaplasmosis granulocytic yabantu kakhulu qho abhalwe ithi mpuma nasentshona.

fever sennetsu

Monocytic ehrlichiosis umntu (Mach) ukuba zizakubalulwa kwakhona ukusuka fever sennetsu - kakubi kakhulu eyaziwa kwaye kunqabile kakhulu sisifo esosulelayo ukubayinxalenye okuninzi kwe ehrlichiosis yabantu ezibangelwa iintsholongwane kunye igama ngokufanelekileyo - Ehrlichia sennetsu. Kwiiveki ezimbalwa emva kokuba usulelo lokuqala nezimpawu ezifana imiqondiso eziqhelekileyo Mach: esibukhali ukunyuka kweqondo lobushushu emzimbeni, intloko ebuhlungu, iintlungu kwezihlunu (myalgia). Ezinye izigulane kufuneka isicaphucaphu, ukugabha okanye ukulahleka wokutya de anorexia. Ngaphezu koko, iziphumo zeemvavanyo igazi kubonakala ukunciphisa izinga amhlophe egazi count (leucopenia) kunye nokwanda zophendlo lwezifo xa umthamo enzyme zesibindi. Le yenethiwekhi (okanye yenethiwekhi) sennetsu fever nangoku ngqo kuqiniseka; ezinye izazinzulu kubonisa ukuba abe namakhalane, ngoxa abanye abaphandi bathi ukuba esi sifo zosuleleke emva kokutya intlanzi ekrwada. Okwangoku, izifo kwenziwa kuphela ngasempumalanga Japan kunye Malaysia.

Lyme borreliosis

Lyme borreliosis - sisifo esosulelayo esibangelwa ziibhaktheriya, spirochetes lentsapho Borrelia. Zenethiwekhi vredosnosnyh amagciwane Ixodes scapularis. Kwiimeko ezininzi, esi sifo inkangeleko ngokuyintloko wabonisa ukufukuka obomvu kakhulu eluswini, leyo bubuso yokuqala kwindawo waphakamisa elijekelezayo lwe ubungakanani obuncinane (papules). Papule iqala ukukhula ngokukhawuleza yaye ekugqibeleni ufikelela iisentimitha ubuncinane ezintlanu ububanzi. Emva koko kukho symptomatology, nezibonakalisa kunye ehrlichiosis umntu monocytic. Amathuba osulelo lwe Lyme borreliosis usezantsi kakhulu umngcipheko zibambe Mach, kodwa ezohlukileyo uxilongo kuhlala inyathelo kuyimfuneko ekumiseleni usulelo. Izigulane Lyme borreliosis nabo badla akhalaze fever (hayi nje esibukhali kwaye iyingozi, njengoko e Mach), kuthibaza, myalgia, intloko ebuhlungu, ubuthathaka, ukudinwa, kunye nobuhlungu okanye ukuqina kwamalunga ezinkulu (samathambo ezosulelayo), ngokuqhelekileyo kwi ngamadolo. Le symptomatology lungaluhlobo yemijikelo yomhla nezolo. Kwiimeko kakhulu, ukuba ekhohlo zizigulo zemithambo ofunda lunganyangwa kunye nezifo ze imisipha yenhliziyo. Ngokutsho manani, uninzi Lyme borreliosis ifumaneka United States mpuma. Nangona kunjalo, kukho iimeko osulelo kunye kwamanye amazwe, kuquka China, Japan, Australia, nakwamanye amazwe aseYurophu.

piroplasmosis umntu

Monocytic umntu ehrlichiosis, amathuba osulelo leyo ingaphezulu ngaphezu ingozi yosulelo kunye nezinye iintsholongwane, asiyiyo esosulelayo isifo kuphela ezinokuba yingozi olwenziwe ngeetikhi. Piroplasmosis umntu (ngamanye amagama - babesiosis) - kukho usulelo okubangelwa micro-elilodwa olunye-ukususela kusapho Babesia. Kaninzi oku sifo sichaphazela izilwanyana, kodwa maxa wambi kukho amatyala abantu abosulelwe yi kuyo. Ngokukodwa, kukholelwa ukuba samakhalane abathwali Babesia ezinokuthi parasitize umzimba womntu. Piroplasmosis ngathi ehrlichiosis umntu iimpawu zokuqala monocytic: izigulane ezikhala ifiva, kuthibaza, intloko ebuhlungu kunye neentlungu kwezihlunu, isicaphucaphu, ukugabha. Ngapha koko, zikhona ngezenzeko ezingaqhelekanga njengoko intshabalalo ngaphambi iiseli ezibomvu kwegazi (hemolytic anemia), ukuhla ezingaqhelekanga amanani zazo (thrombocytopenia), ukuncipha kwenani cell zegazi ezimhlophe count (leucopenia), kunye wawandisa udakada (splenomegaly). Abantu kunye neempawu zinyange ngokwanelisayo zinokwahluka ukuthamba okanye engekho ngokupheleleyo. iimeko ezimandundu of piroplasmosis umntu waphawula kwizigulane obekhe wenziwa utyando ukususa udakada (splenectomy) okanye inkqubo buthathaka omzimba. Kakhulu sivame ukuxilongwa babesiosis yabantu kumantla eUnited States, kodwa kukho amatyala ubhaqo lwalo kumazwe aseYurophu.

American lwethikh yesifo

Monocytic ehrlichiosis umntu kufuneka ahluka ukusuka American lwethikh ricketsiosis - isifo esinqabileyo esosulelayo esibangelwa bacterium yintsapho Rickettsia. ulawulo kumda wesangqa izinambuzane efanayo ezingasosulela le ehrlichiosis monocytic yabantu. Xa yesifo baphawula ebuhlungu kakhulu kunye nobuhlungu bomzimba, ifiva, kuthibaza, ilahleko yokuqhelaniswa nezifundo emajukujukwini. Kwiimeko ezininzi, emva emibini - kweentsuku ezintandathu emva tick inyeke kukho ukujaduka eluswini, ikakhulu ukuyigubungela ezintendeni, ezihlahleni, ekuncothukeni kweentende zeenyawo, Amaxhwele kunene. Kamva, le ukujaduka kuthe kwaqhenqetha ngokusekuhleni, umntla kunye umzantsi womlenze. Ngamanye amaxesha kukho isicaphucaphu, ukugabha kunye neentlungu esiswini. Kwezinye iimeko, xa sifo na olufunyanwa kwexesha, okanye xa engekho unyango olwaneleyo, iimpawu nokutsha komphathi wokukhusela-ebemzele US ricketsiosis inokuba ubomi engozini. Uqhambuko esi sifo ibhalwe kwiingingqi ezahlukeneyo US.

ekuxilongweni

Nokuxilonga ehrlichiosis yabantu monocytic, usulelo onako ukwenza iimpawu ezinokuba yingozi, kufuneka usebenzise uvavanyo lonyango, uhlalutyo iimvavanyo izifo-free kunye kwilebhu ezizodwa. iimvavanyo zegazi zidla ngokubonisa kubonakaliswa ngumntu ehrlichiosis monocytic oluntu: ukuhla ebomvu legazi count (thrombocytopenia), ukuncitshiswa abamhlophe cell count (leucopenia), kunye nokwanda ngaxeshanye kwinqanaba enqanda ezithile kwesibindi (isi-serum aspartate aminotransferase kunye aminotransferase alanine). Kwezinye iimeko, ngenxa nemvavanyo zaselaborathri wafumana cerebrospinal zophendlo lwezifo fluid. Ukongeza, isifuba X-reyi ulungisa utshintsho ezingaqhelekanga emiphungeni (umz lingene pulmonary okanye incindi beqokelela excess).

Uphando igazi smear phantsi electron-beam microscope bangabhaqa ukuqokelelana iintsholongwane kwi vacuoles iiseli ezithile (ingakumbi monocytes), kodwa nisaqala zosulelo izihloko ezinjalo ebonakalayo. Kwezinye iimeko, iimvavanyo ezongezelelweyo ilebhu ezizodwa ukugqiba udidi oluthile yosulelo kwaye uqinisekise uxilongo.

iimvavanyo ezifana ezizodwa ziquka, umzekelo, indlela immunofluorescence ngokungangqalanga ezimbi uzingela, nto leyo ibandakanya ukufunda serum eveliswa ngenxa yegazi yomguli. Izilwa - iiproteni eziveliswa iiseli ezithile zegazi ezimhlophe - kunceda ubuthi umzimba ekulweni kunye iintsholongwane eziyingozi. Xa usebenzisa ngqo immunofluorescence amabala omzimba athile oluntu ilebhile iidayi ezijiko-jiko, serum yabekwa phantsi imitha yelanga kunye sihlolisise oko phantsi ngemicroscope ukuchonga lomzimba reaction njengamacala ukuba iintsholongwane ezithile.

unyango

Xa kuqinisekiswa une "ehrlichiosis monocytic zabantu," kunokuba ukunyanga esi sifo? Amaninzi, oogqirha amisele idosi umgangatho antibiotics tetracycline. Njengoko enye uthomalaliso wambi kusetyenziswa ngokusekelwe doxycycline. Kwiimeko kakhulu, isigulane basenokufuna kweliso yobungcali esibhedlele. Ukongeza nemithi, kunokwenzeka ukuba imvume nawuphi na ugqirha amayeza xa ukuze kulungiselelwe iimpawu eziye osulelo.

ukuvimbela

Ukuba uhlala kummandla kuyo, apho kuhlala ngeetikhi eziyingozi, kuquka abathwali iintsholongwane usapho Ehrlich, kungakuhle ukuba uthathe imiqathango efanelekileyo. Ukuba bashiya ilizwe, khumbula ukuba wena ngaloo ukunyusa ingozi yokosulelwa sisigulo kakhulu ezifana ehrlichiosis umntu monocytic. Photo ntwala iqinisekiswa abathwali iintsholongwane, uya kuhlala eyingcathu, Noko ke, ukuze ukwazi utshaba enokubakho ebusweni akwanelanga. Nxiba iblukhwe ende, shirts T-shirt enemikhono emide. Kubalulekile ukunxiba iminqwazi, eyona - iminqwazi emikhulu, njengoko amangolwane abaninzi bahlala emithini. Khetha impahla ukukhanya-bala, ekubeni kulula ukubona yesinambuzane. Sebenzisa i ezizodwa izixhobo-mathumbu kwaye uqiniseke zombini ulusu kunye nempahla ngokufuthi shot. Uninzi ukulunywa tick kwenzeka entlonzeni kunye nentamo.