"Metformin" (tablets): yesikhokelo, ncomo, ukwakheka, ukusetyenziswa kunye nobungozi umzimba

Isifo seswekile - sesinye sezifo ixhaphakileyo ehlabathini. Qho ngonyaka inani lamatyala kabini. Diabetes sinwenwa senzeka enokuphazamisa pathways kweentlobo ezimbini - xa incindi yomzimba ayanelanga (uhlobo lokuqala) kwaye ukuba ukusebenza aphazamiseke insulin kwi zomzimba (Uhlobo lwesibini). Type II diabetes kwenzeka ngo-80-90 ekhulwini zonke iimeko kwaye kuvamise zizinto ezingemnandi ezifana ezifana nokutyeba. Xa unyango lwezifo ngaphaya kwendakhe zingqineke ichiza "Metformin" - tablets, leyo ngenxa iimpawu zawo zithandwa kakhulu phakathi kwabo bafuna ukunciphisa umzimba, kodwa ugula sisifo seswekile.

Yintoni "Metformin"

"Metformin" kunye analogue zayo - amachiza hypoglycemic ezimiselweyo ukunyanga isifo seswekile - ikakhulu udidi lwesibini, kodwa kwezinye iimeko indlela eyamkelweyo kunye nohlobo lokuqala. Okokoko yathi yasekwa ngo-1957, "metformin" uhlala ichiza okhokelayo kunyango seswekile, ingakumbi xa iingxaki ezifana nokutyeba. Insulin ikhuthaza yokugcina ezityebileyo, yaye "metformin", ekunciphiseni amanqanaba insulin emzimbeni kwaye inceda balahle loo nto. Kungenxa kwesi senzo, abaninzi esetyenziswa njenge ekunciphiseni "Metformin" kwipilisi.

Ubume "Metformin," Amacwecwe

UKwakhiwa amacwecwe iquka isithako metformin hydrochloride esebenzayo, nto leyo yenziwa zizinto zendalo ukuba afunyanwa ukusuka Lilac French nezenxina yebhokhwe. Excipients ukulungiselela - talc, umbona starch, nemagnesium stearate, titanium dioxide, kunye povidone K90, crospovidone kunye macrogol 6000.

Ubungqina obubonakalayo buxela ukuba Ukwamkelwa "Metformin"

Ubukhulu becala "metformin" - iipilisi ukuba emiselweyo uhlobo seswekile sinwenwa 2 ngaphandle utyekelo ketoacidosis (ukuphazamiseka emzimbeni ekudleni ngenxa yokungabikho insulin). Ingakumbi xa ichiza ubonisa ukutyeba nomonde xa unyango edla angasebenzi. Kwakhona ukuba ukutyeba kwayo linokukwenziwa xa zidityaniswe ne-insulin.

Ngesi uphethwe, ezifana neswekile, "Metformin" icwecwe elawulwa njengoba kulungiselelwa eyahlukileyo okanye zidityaniswe kunye arhente antidiabetic namanye amaqela, ukuba sithetha kuhlobo lwesibini. Xa Uhlobo lokuqala ngayo ilawulwa esetyenziswa ukuncedisana ne-insulin esisiseko.

izifundo zenzululwazi akutsha nje abonisa ukuba "metformin" lisetyenziswa ngempumelelo unyango seswekile ezinxulumene-Oncology.

Isenzo metformin

Metformin kwandisa uvakalelo weseli insulin. Inqanaba glucose igazi nokuphungulwa kunye cholesterol. Izithako ezisebenzayo inkqubo yokulungiselela isebenze igcwala ezityebileyo, musa ukuvumela carbohydrate ukutya kwaye kuthintela nokwanda kwamafutha emzimbeni.

Insulin ekwenyukeni inkqubo yamafutha, ingakumbi kwiindawo eziyingxaki (ngakumbi, isisu). Ngoko ke, ukutya ezininzi isekelwe kwinto yokuba asuse ukutya ukudla ukwandisa amaqondo eswekile yegazi. Metformin kwakhona ofihla indlala okubangelwa insulin.

ifomu Ukukhululwa balawule

"Metformin" - tablets wawutyabeka, 500, 850 kunye 1000 mg, xa imiqulu blister apho zikhutshwa ngeenyama-10, zimhlophe ngokwebala. Qala unyango kunye 500-1000 mg ngosuku, oko kukuthi macwecwe 1-2. Umthamo, ngokuxhomekeke kwinqanaba iswekile egazini, ukuba kancane kancane emva kweentsuku zokuqala 10-15 unyango, kodwa kufuneka uthathe mg ngaphezu kwama 3,000 ngosuku. ithamo Ulondolozo - 1000-2000 mg (3-4 tablets). "Metformin" umyalelo nayo akucetyiswa ukuba athathe idosi abangaphezu kwe-1000 mg ngosuku abalupheleyo.

Iipilisi zenziwa ngokupheleleyo ngexesha okanye emva kwesidlo, ahlambe phantsi ngamanzi. Ngamanye amaxesha umbuzo wokuba ngaba kunokwenzeka ukuba ayahlule cwecwe ( "Metformin") kwisiqingatha. Xa kufikwa ne nedosi ye-500 mg, ukuba benze into engekho kuyenzeka, njengoko idosi esezantsi ayiniki yifuna, kaloku ke, ayikhuthazwa ukuqhekeza yesikhumba ehlanjiweyo, ukuba babugubungela tablet. Ukuba kunzima nje ukuginya ngenxa ubukhulu, ngoko lungohlulwa lube iinxalenye ezimbini kwaye bathathe inxaxheba - kodwa inxalenye nje omnye emva komnye.

Ekubeni "Metformin" anganika iziphumo ebezingalindelekanga kwi phecana zesisu, ithamo yemihla ngemihla kufuneka luthathiwe yonke ngexesha elinye, kodwa amathamo amabini okanye amathathu ngexesha lasemini, kungcono xa zisitya. Ukuba ufumana ukuphazamiseka kakhulu pathways, ithamo kufuneka incitshiswe.

Xa kunjalo, ukuba kufuneka uthathe amanye amayeza kwixesha efanayo, xa uthatha "Metformin" (tablets), umyalelo manual iqulathe ulwazi malunga apho amayeza zinokudityaniswa with "metformin", yaye akakwazi. Kwakhona, qiniseka ukuba udibane nogqirha wakho malunga intsebenziswano phakathi arhente ezahlukeneyo with "metformin".

analogs

Kwiimeko ezininzi, izigulane anomdla analogue amachiza - zitshiphu ngakumbi okanye olusebenzayo, kuquka xa kufuneka iipilisi ze seswekile. "Metformin" iye nucleoside ezininzi sinezinto ezifanayo kubo umgaqo amanyathelo. Okokuqala "Glucophage" yaye "Siofor", omnye ezizezinye othandwa kakhulu, "metformin" kwakunye njenge inani nezinye iingxowa babe yinto efanayo esebenzayo, ukuze ngokufanayo kuchaphazela umzimba kwaye babe iziboniso okufanayo ulwamkelo, leyo "Metformin" kwipilisi. Izimvo analogue uyakwazi zifundwe kwi Internet, unako kwakhona thelekisa imiyalelo ukusetyenziswa, ukuba izigqibo ukhethe ichiza ilungileyo.

Analogs "Metformin" zezi:

• "Bagomet";
• "Hexane";
• "Glucones";
• "Gliminfor";
• "Metospanin";
• "Metfogamma" (500, 850, 1000);
• "Nova Met";
• "NovoFormin";
• "Sofamet";
• "Formetin" kunye nabanye.
• "Siofor" (500, 850, 1000) - iziyobisi German, wathabatha ngomlomo, abe isiphumo hypoglycemic, ephunyeziweyo yokutshintsha elisemagqabini-insulin.

Njengoko for "Glucophage", kokukhona ebiza kakhulu ukuba "Metformin" kodwa xa izigulane kokungeniswa 50 ekhulwini amathuba okuhlaselwa ukusuka ukuphazamiseka kwenkqubo zesisu. "Glucophage" ubonisa uhlobo lwesibini seswekile, kusetyenziswa zombini yedwa kunye zidityaniswe namanye amachiza. Ukwahlukana "Glyukofazh Long" lilandisile ithuba lokuba semthethweni.

Ngokusisiseko, onke la machiza kufuneka isenjalo umgaqo ephilayo, ngenxa yokuba into esebenzayo enye core layo.

Kukho izongezo zokutya ezinceda ukuthoba izinga glucose igazi:

• "Vidzhar" (kwakhona zehlisa cholesterol, iyazingenela amajoni omzimba ophazamisa uphuhliso izifo ezosulelayo amagciwane);
• "Spirulina" (luncedo ukuphazamiseka kweenkqubo pathways, ekulweni ubunzima kwemfuneko);
• "Glyukoberri" (lunciphisa ubungozi iingxaki diabetes), kunye nabanye.

Noko ke, izongezo zokutya engamelanga ithathwe njenge indawo epheleleyo ichiza, ukuba zingasetyenziswa njenge kwisi kunyango esisiseko. Ukongeza uBud kufuneka udibane nogqirha wakho malunga noku.

"Metformin" in diabetes

"Metformin" - enye arhente best anti-seswekile namhlanje. Yeyokuba isebenza kakhulu unyango lwe uhlobo seswekile, iya kuqhutywa kunye insulin, kwaye idosi lukhethiwe ngokuxhomekeke kwisixa glucose egazini.

Xa unyango seswekile, oko abangaphangeliyo gluconeogenesis, ngaphandle kokuchaphazela inqanaba insulin egazini. Kwakhona kwandisa kwegazi negazi esibindini, sivumele iswekile ngokukhawuleza ajikwa glycogen.

Xa ukuphatha uhlobo seswekile II , "metformin" banokuthi banyulwe ubomi. Ukuba ibhalwa idityaniswe nezinye izinto antidiabetic, kuyimfuneko ukuba esweni umgangatho glucose ukuze uphephe hypoglycemia. Xa yolwamkelo elahlukileyo ichiza akuthethi ukuphuhlisa hypoglycemia.

Ukongeza, ukuba isetyenziswa kunyango izigulana ukutyeba, nto leyo edla ikhapha seswekile njengoko ofihla wokutya kwaye kunciphisa kukufakwa glucose ekutyeni kwi lokugaya.

Xa Uhlobo lokuqala ichiza esetyenziswa ukuncedisana ne-insulin kunye nezinye izinto seswekile, yedwa oko kwenziwe kuphela uhlobo seswekile 2. Ekuqaleni unyango, "metformin" yokwamkela nezinye izinto hypoglycemic kufuneka imiswe.

unyango "Metformin" une kwamnceda phambi kokuba pathways syndrome kunye lipid ukutya ukuphazamiseka.

syndrome pathways - ngumqathango lomzimba, apho inani sodade zinto: kakuhle carbohydrate ukutya, isigulana unesifo lwegazi, ukutyeba, njl sifo lukhatshwa ingozi enkulu yokuba nesifo sentliziyo .. Isiseko sale meko ukunganyangeki insulin, apho, ngokutsho zophando lwakutshanje, ngokusondeleyo kunye seswekile kunye nesifo semithambo.

Ngokubhekiselele lipid ukutya, ngenxa zophando yafunyanwa ukuba umgangatho triglyceride, cholesterol iyonke kunye LDL cholesterol kuyehla xa uthatha iipilisi ze seswekile "Metformin". Ukuphonononga izazinzulu ngale chiza kwakhona iqulathe ulwazi ngempumelelo yalo ekuthinteleni seswekile zohlobo lwesibini xa besaphula ukunyamezelana ekudleni.

"Metformin" ekunciphiseni

Iimpawu ezikhethekileyo ichiza nezingqinekayo ubunzima ilahleko izigulane seswekile kukhokelele ekubeni "Metformin" kwakuxhaphakile phakathi kwabo bafuna ukuncipha.

Ngaphandle kwento yokuba ichiza kuqala iinkqubo ezinceda ukuba aqhumisele ngamanqatha abangaphezu kwemfuneko kunye musani ukwenza iidipozithi ezityebileyo entsha, esebenza ngayo kubantu ngaphandle seswekile, ngononophelo, yaye kubalulekile ukuba uthathe ingqalelo ngexesha elinye iqela iimeko.

Okokuqala kufuneka sikhumbule ukuba ichiza asibikho aqhumisele ngamanqatha, kodwa inceda ukuchitha kuphela surplus yayo kwimeko apho oku kwakhona ekhatshwa umthambo esebenzayo kunye ukutya okhethekileyo. "Metformin" - pilisi na kwiipropati ngokungummangaliso, kodwa kuphela isixhobo olongezelelweyo. Nokuba phakathi koogqirha akukho uluvo olunye ngomntu bakwazi 'Metformin "ipilisi: okulungileyo kunye nobungozi kulo mzimba woku ichiza kufuneka bavavanywe ngabanye kwimeko nganye. Abanye oogqirha uyakukumisela lona ukuba umguli ukuphulukana ngokukhawuleza ubunzima, ngoxa abanye bakholelwa ukuba luyingozi kakhulu emzimbeni. Ngoko ke, xa kwehle ubunzima ngoncedo "Metformin" zoviwo lokulungiselela nezoviwo kokubonisana ingcali efunekayo ukuze benze isigqibo esifanelekileyo.

Okulandelayo, kufuneka uthathe ingqalelo inani Izimo. Umzekelo, ukuba une iswekile Uhlobo yokuqala okanye yesibini ngaphandle insulin, nika "metformin" nokusombulula iingxaki kunye kwehle ubunzima ungasebenzisa kuphela endocrinologist.

Kuyo nayiphi na imeko asikwazi ukuthatha beziyobisi kwizintso, intliziyo, ukusilela lung, isifo zesibindi, igazi.

Ichiza asinakusetyenziswa xa umzimba buthathaka - emva kotyando, kwentlungu, isifo kakhulu, kufuneka kuphetshwe ngexesha izifo ezihlasela zosulele ezosulelayo.

Akuvunyelwe ukuba athathe "Metformin" ukuba unamathele ukudla eliphantsi.

Iinkqubo eziphambili ukuba kwenzeka emzimbeni ngasemva, "metformin" unyango kunye negalelo ilahleko ubunzima, kuba:

• igcwala fat rapid;
• ukwehliswa nokwenziwa carbohydrate;
• izinga le glucose ngcono kwezihlunu kwezihlunu;
• ukunciphisa iimvakalelo yindlala, nto leyo ubunzima bomzimba elincitshisiweyo.

Ongalawulekiyo ubunzima ukulahleka nalo eli chiza rhoqo ziziphumo ebezingalindelekanga, ingakumbi xa sele uthathe idosi enkulu ngaphezu uvumelekile ngokwemiyalelo. Ukongezelela kwiingxaki elibalulekileyo iphecana zesisu, unako fehle, ecubhukile, ngababuthuntu, ukuze aphuhlise lactic acidosis okanye na isifo esimandundu.

Kwakhona, xa benikwa "Metformin" imfuneko ukulandela ukutya. Xa ngaphandle iilekese, ipasta, iitapile, iziselo. Ukutya kufuneka kube rhoqo kuwe, awukwazi yindlala, kodwa ixabiso lesondlo kufuneka abe ngaphezu 2500 kcal ngosuku. Ngeli xesha, kufuneka usele kangangoko kunokwenzeka amanzi yesiqhelo acocekileyo.

Nangona isibakala sokuba "Metformin" ishenxisa imfuneko ukuzibandakanya umthambo enzima emzimbeni, oko akuthethi akuthethi ukuba umzimba iphetshwe. imithambo Morning, iindlela ezisebenzayo zolonwabo, imithambo neiznuryayuschaya edityaniswe ngamayeza kunokunceda kakhulu ngokukhawuleza ukuba balahle fat kwemfuneko. Akukho mfuneko yokuba nethemba lokuba "Metformin" uya kwenza yonke into kuwe kungekho iinzame olongezelelweyo kwakho!

Ukuze ufumane inxaxheba ichiza aze ayise kwi umgaqo "kokukhona - ngcono" ayikho: Musa ngaphezulu ithamo, ukuba uthatha "Metformin" (tablets). Imiyalelo yokusebenzisa unika isikhokelo esicacileyo malunga idosi iphezulu imali ukungathobeli-nto leyo banokubenzakalisa kakhulu emzimbeni. Ukongeza, eli chiza zingasetyenziswa elingekho ngaphezu kweenyanga ezintathu, ngoko ufuna ukuthatha ikhefu.

Ngoku ungakwazi ukufumana okuninzi reviews abo bathatha "Metformin" iipilisi yokudla. Ukuphonononga ngendlela ezahlukeneyo: umntu Wazisusa amanqatha abangaphezu kwemfuneko ngokukhawuleza isigxina, umntu kuthintele imikhwa emibi okanye kwiziphumo ebezingalindelekanga. Kodwa ngokubanzi, sinokugqiba ukuba abo "Metformin" zanceda ndibuthabathe phantsi kweliso kwagqirha, kwakubon 'ukuba kunciniwe, ukusebenzisa ukutya efanelekileyo kunye umthambo bezorhwebo buphuhliswe kamva.

Izimo ukuba "Metformin"

Phambi kokuqala unyango, "metformin", kungakhathaliseki ukuba ingaba seswekile okanye ukuba ufuna ukwehlisa umzimba, kufuneka ukuba uqhelane kunye uluhlu onomtsalane Izimo aze adibane nogqirha.

Inani Izimo ezi kwezintso, igazi, insufficiency yemiphunga, ngezifo kakhulu wesibindi iphecana biliary; izifo ezingapheliyo amalungu zifo. Ichiza kufuneka kuthathwe kwi maxesha post-traumatic kunye post-operative, kwakunye iqhosha post-engabalulekanga ngexesha kwimeko yesiqhelo. Ukwamkelwa "Metformin" into contraindicated kwiinkqubo esosulelayo kwaye ukudumba kunye exacerbation nasiphi na izifo ezingapheliyo, iintlobo okunzima kwegazi.

Ichiza akuvumelekanga ngethuba lokukhulelwa zisanyisa. Xa becwangcisa isifundo ukukhulelwa okanye kokukhubazeka kwakhe kwisiqalo reception "Metformin" beziyobisi efunekayo ukuze izakunikezela kwaye badlulele kuthomalaliso insulin. Ibele, ukuba ufuna ukuluphatha, "metformin", kufuneka ukurhoxisa, kuba akukho data kwi isiphumo nesiyobisi ubisi lwebele, kodwa inxalenye encinane ichiza ongene ubisi kuyingozi umntwana, njengoko kwenani Izimo - ubudala 18 iminyaka. "Metformin" akukho eboniswe abantwana abafikisayo abangaphantsi kweminyaka engama-18.

Kwakhona, "Metformin" akumele kuthathwa kwimeko ubunxila ubuthi utywala oyingozi. Ngokubanzi, kuyimfuneko ukuba ukwala ukuthatha utywala kunye amayeza ethanol aqulethe, ukuba uthatha "Metformin". Inyaniso ukuba udibaniso lwe metformin kunye ethanol nkqu iingedosi ezincinane, okuvuselela uphuhliso laktotsitoza ngokukhawuleza, de kuse ekufeni.

Kuyingozi ukuba "Metformin" kwi rhoqo ephantsi-osidingayo nedayethi "yindlala".

It ingenakuthatyathwa ngabantu abangaphezulu kweminyaka engama-60 xa bathe benza yezandla enzima, ukunqanda uphuhliso lactic acidosis.

Ngexesha unyango, izigulane kufuneka ukuba esweni umsebenzi kwezintso, esweni umgangatho zincancise kwi-plasma, creatinine serum.

imiphumela emibi ichiza

"Metformin" evusa inani yeziphumo ebezingalindelekanga. Ngoko ke, xa unyango kuyimfuneko ukuba esweni ngenyameko imeko yento ephilayo kunye ukubonakala izikhalazo udibane nogqirha ngokukhawuleza, ingakumbi ukuba ngaba uthatha amayeza hayi emiselwe ngugqirha kunye ngokwakho.

Ichiza lokuqala ebangela iintsilelo kwi inxalenye phecana zesisu. Kulo mzekelo, iimpawu ezingemnandi kunokwenzeka ezifana:

• isicaphucaphu;
• ukuphalaza;
• sorhudo ziqhu;
• flatulence;
• ukulahleka emnyama;
• imbonakalo sisinyithi isongo emlonyeni;
• imbonakalo iintlungu esiswini.

Kwakhona, isigulane usenokukhalaza ukusilela yokuphefumla, tachycardia, irhashalala kunye desquamation ulusu, ngokufuthi kunye ukurhawuzelela.

A effect icala ezinqabileyo kodwa yingozi - lactic acidosis. Xa lactic acidosis, lactic acid engena egazini, iimpawu yokuqala - ubuthathaka, ukozela, ukudinwa, ukwandisa isicaphucaphu, ukugabha.

Xa ulawulo ezingapheliyo lukaMeyi zesibindi kwekhono iziyobisi.

Ukuba ubona ubuncinane enye yezi mpawu, kufuneka ngoko nangoko udibane nogqirha imxelela ukuba uphu-, "Metformin" kwipilisi. Iinzuzo kunye Ayize nakanye umzimba kule kunokwenzeka obungalinganiyo, mhlawumbi kufuneka ukuba uthathe iziyobisi kufuneka ukufumana enye indlela yonyango okanye ukwehla kobunzima bomzimba.

isishwankathelo

"Metformin" - olona hlobo lusebenzayo kuxa uhlobo tablet 2 seswekile. "Metformin" Kwakhona inceda ukwehlisa ubunzima, kodwa kubalulekile ukukhumbula ukuba eli chiza Ayilochiza, ayithethi indawo yokutya ephantsi-carb kunye umthambo. Therapy "metformin" kufuneka sikhatshwe ulawulo kwamanqanaba igazi glucose ekuphepheni imikhwa emibi, kuquka ukutya. Ukuba ufuna ukunciphisa umzimba nalo, musa ukunikezela gym, yitya, kwaye musa ukulibala ukuba kuqala iba amayeza kakhulu, oko yenzelwe ukujongana seswekile, ngoko kuyimfuneko ukuba isilumkiso yaye kuphela emva kokudibana nogqirha wakho.