"Metadoksil": ngokutsha otywala, imiyalelo ukusetyenziswa, ukubunjwa kunye nenkcazo

Njani ngempumelelo liziphatha iziyobisi "Metadoksil"? Izimvo iindlamanzi ixabiso le mveliso kunye nokubonakaliswa yayo kuxoxwa ngezantsi. Kwakhona kweli nqaku, uza kufunda indlela isicelo beziyobisi, iziphumo zalo ezisemacaleni Izimo.

Inkcazelo, uhlobo, ukubunjwa

Drug "Metadoksil" (ncomo iindlamanzi malunga iya kuboniswa ngezantsi) ifumaneka ezithengiswayo kule fom zilandelayo:

• Biconvex, amacwecwe emhlophe ngeenxa kunye Valium ngapha ematyeni kunye negama lemveliso - phezu kwezinye. isithako yayo esebenzayo i L-ezimbini pyridoxine pyrrolidone carboxylate-mihlanu ngokuba metadoksin. Baqukiwe kwesi sixhobo unguye MCC nezinki stearate.
• Isisombululo ngokucacileyo ukuba isitofu yi ithinti ezingenambala okanye elityheli. icandelo yayo nayo metadoksin. Ngaphandle kulo, kwi ekwakhiweni ichiza iquka sodium edetate, amanzi d / kesodiyam metabisulfite kunye methyl parahydroxybenzoate.

ukusebenza beziyobisi

"Metodoksil" - unyango butywala. Kwakhona yindlela ukubonisa ezigulela kunye neempawu hepatoprotective.

ukusebenza Hepatoprotective beziyobisi ngenxa inwebu isiphumo yayo. Ukongeza, eli chiza ikwazi ukunciphisa umlinganiselo simahla unsaturated okunamafutha igcwaliswe. Ngenxa yokwanda ukumelana imiphumo hepatocyte peroxidation kwamafutha evela phantsi kwempembelelo eziyityhefu.

iimpawu detoxification beziyobisi ngenxa ukusebenza enqanda kwesibindi aqukiweyo nethe-ethanol (ingakumbi dehydrogenase utywala kunye acetaldehyde dehydrogenase), ibalekisa kakhulu inkqubo kususwe ku emzimbeni kwaye, ngenxa yoko, lunciphisa isiphumo ityhefu.

iimpawu iziyobisi

Yintoni na iziyobisi ephawulekayo "Metadoksil"? izilinganiso zemiyalelo bathi ubuncwane bayo esebenzayo kuthintela ukuyilwa izinto ezifana collagen kunye fibronectin, kwaye uthintele beqokelela triglycerides, leyo ukucola kakhulu uphuhliso ngokoma.

Kufuneka kuqatshelwe kanjalo ukuba esi sixhobo uyakwazi ukunqumlela ixesha isiqabu of uyeka, ukunciphisa iimpawu somatic kunye zengqondo ibhabhalaza.

Asikwazi ukuba metadoksin iyazingenela Gaba-ergic kunye nenkqubo neurotransmitter cholinergic kuthintela motor excitation, iphucula inkumbulo kunye nokucinga elifutshane. Ukongeza, into ekwaziyo unenye imiphumo nonspecific anxiolytic kwaye bucala, kwakunye nokunciphisa njengokufuna utywala.

kinetics

Emva ukuthatha iyeza ngaphakathi ako ngokukhawuleza ukusuka emathunjini. Metadoksin has a bioavailability eliphezulu (malunga ne-60-85%). Its ukuzenza iiproteni plasma yi-50%.

Eli candelo umzimba esibindini ukwenza yezabelo esebenzayo - pyrrolidone carboxylate kunye pyridine.

Half-ubomi kweziyobisi ngabaphethe parenteral okanye nokudla imizuzu 45-57. Malunga nama-40-50% beziyobisi livela umchamo emini malunga 35-50% - endleni kwisithuba seeyure ezingama-95.

ubungqina

Kuphantsi kwaziphi iimeko apho eli chiza isebenzayo liziphatha "Metadoksil"? otywala Ukubuyekezwa bathi eli yeza lulunge kakhulu:

• utshwala;
• kwi ekunyangeni isifo sesibindi, kuquka umyalezo utywala;
• utywala ekubalekeni syndrome ;
• ukunxila okanye utywala, kuquka yondele.

Izimo

amayeza kubhekwe contraindicated ku:

• lwebele;
• yokumitha;
• uvakalelo oluphezulu ukuya iziqalelo ichiza.

Ngokukhathalela sibonelelo kufuneka zisetyenziswe Parkinson, ingakumbi xa isigulane sele usebenzisa levodopa. Oku kungenxa yokuba metadoksin sikwazi ukunciphisa ukusebenza kwale yokugqibela.

Drug "Metadoksil": imiyalelo yokusebenzisa

Ukuphonononga ingxelo yokuba ukusetyenziswa kwe-mali kufuneka ube kuphela emva kokubonisana yincutshe.

Xa ukunxila okanye utywala, ingakumbi etsolo isiyobisi, asebenzayo elawulwa intramuscularly kwi umthamo 300-600 mg okanye butofelwe - 300-900 mg.

Xa kulawulwa yegazi, ithamo iziyobisi kubonisiwe ngaphambili exutywe isisombululo dextrose-5% okanye ml 500 sodium chloride. Ngefomu ukulungiswa yaziswa dropwise, iiyure 1.4.

Njengenxalenye yonyango ezidibeneyo izifo zesibindi, kunye utywala esinganyangekiyo isixhobo 500 mg ezilawulwa kabini ngosuku imizuzu 25-35 phambi kwesidlo. Le ithamo angandiswa ku 500 mg kathathu ngemini.

Ikhosi unyango kunye eli chiza kufuneka kuthabatha iintsuku ezingama-90.

Xa abstinent syndrome (utywala) kwi medicament ilawulwa yegazi ngokuthi ukumnika kwi ne nedosi ye-900 mg kanye ngemini kangangeentsuku 3-7 (ngokuxhomekeke isigulane).

imiphumela emibi

Yintoni isenzo esibi liyeza "Metadoksil"? Izimvo ukuphuza ingxelo ukuba kwimeko zokusebenzisa oku kuthetha bavame negazi lakho.

Kufuneka kuqatshelwe ukuba abantu bronchospasm kunokwenzeka nesi sifo inyumoniya (rhoqo xa usebenzisa isisombululo).

ulwazi oluthile

Ewiliko for "Metadoksil" isitofu iqulethe icandelo ezifana sodium metabisulfite. Le eziphathekayo kunokubangela ukuhlaselwa sisifo sombefu kubantu abanobuntuntunu negazi lakho, kwakunye okhulisa zabo.

Drug "Metadoksil": ncomo otywala

Ngelishwa, reviews elungiswa "Metadoksil", akukho kakhulu kunene. Noko ke, abo zashiya abantu ezithandwa butywala, sinako singatsho ukuba ichiza kunempembelelo entle ukunyanga ukuxhomekeka etywaleni.

Ke ukusebenza konyango lwe uyeka, ingxelo isigulane abahlukene ezahlukeneyo. Abanye bathi ukuba ichiza karhulumente kukusiza kakuhle, ngoxa abanye - hayi baye baqaphela nasonasiphi na isiphumo.

Kwakhona ndafumana iingxelo ezimbi malunga ixabiso esi sixhobo. Ngokuqhelekileyo, oko 1250-1450 engange.