Iziyobisi umhlaza enamandla konyusa ingozi yesifo sentliziyo?

Kwiimeko ezinqabe kakhulu, iziyobisi ezinamandla, nto leyo eyenza amajoni omzimba ukulwa umhlaza, kungalubeka engozini intliziyo. Oku ingxelo ngabaphandi.

Le mithi immunotherapy. Kwiminyaka yakutshanje, mhlawumbi zitshintshile ngokupheleleyo inkqubo unyango somhlaza, njengokuba ezinye izigulane uthembele konke kwi-ukusebenza yaqala kuxolelwe.

Amatyala wokuqala ukufa

Noko ke, ngoNovemba 3, "New England Journal of Medicine" liye inkcazo amatyala amabini, xa izigulane kwi zigaba kade wolusu wabulawa sisifo sentliziyo iiveki ezimbini emva kokufumana komthamo wazo wokuqala iziyobisi ezifana Opdivo (Nivolumab) kunye Yervoy (Ipilimumab).

Omnye izigulane umfazi oneminyaka engama-65 ubudala ababulawa sisifo sentliziyo, lo gama enye indoda eneminyaka engama-63 ubudala bafa emva amatyala amabini zokuma ngequbuliso. Ngexesha yesifo sentliziyo, igazi kwemali entliziyweni iyabhlokwa, okukhokelela kumonakalo zomzimba, lo gama kwimeko zokuma ngequbuliso, ime ibetha ngokupheleleyo.

Ingozi usebenzisa iziyobisi ezifana

Le ngxelo wongezelela ukuba ezimbini imveliso efanayo imarike - Tecentriq (Atezolizumab), ichiza nomhlaza isinyi, kunye Keytruda (Pembrolizumab), nto leyo esetyenziselwa unyango kwafikela kwi wolusu nobuchopho owayesakuba ngumongameli American uJimmy Carter - inokuba yingozi efanayo .

Kunjalo, amatyala umonakalo intliziyo akuqhelekanga kakhulu, yaye ngaphantsi kwe-1%. Kuthathwa ukuba ingozi kakhulu xa amachiza amabini ziyathathwa ngexesha elinye, yongeza ababhali ngxelo.

ubungqina isazi

Abaphandi Sigxininisa ukuba iingxaki kufuneka kungasuki iinzuzo zezi iziyobisi izigulane ezinomhlaza.

"Le, ingxaki esitsha ngaphambili ayaziwa amayeza ezinokuba zisindisa ubomi," - wathi umbhali kolu phando senior, uGqr Javid Moslehi. Nguye umlawuli we-School of Medicine e Nashville.

"Sizama ukuphuhlisa isisombululo kule ngxaki. Umsebenzi wethu ukuba baqaphele ezi iziyobisi eziyingozi, kunye nokuphucula imeko ", - watsho Moslehi.

Izigulane ukuthatha la machiza kufuneka esweni ngenyameko. Ukuba bathe ngaphandle bafumana le ngxaki entsha, kuya kufuneka ubanike ngokukhawuleza kubo iziyobisi Ndiyijike impendulo amajoni omzimba - abaphandi bathi.

Dr. Michael Atkins, usekela-mlawuli we Georgetown-Lombardi Comprehensive Cancer Centre e Washington, DC, ukholelwa ukuba iingxaki intliziyo okubangelwa ngala machiza, oko ingasombululwa. Atkins owayephethe sifundo, apho wafela evela kwizigulane ezimbini. "Le meko inqabile ... kodwa into embi ngakumbi", - wathi.