Isifo Parkinson, yaye iminyaka yobomi, iimpawu ezisaqalayo, isigaba

Parkinson kaThixo - sisifo eyaziwa eluntwini ukususela kumaxesha amandulo. Xa igqirha ngenkulungwane XIX D. Parkinson uchaze iimpawu uphawu weyiseka ukuba oko enikina elukhukweni enedumbe. Esi sifo ithiywe emva kokuba sisazinzulu - sifo Parkinson kaThixo. Yintoni na? Njengoko yesilungu ubona esi sifo kunye neendlela zonyango?

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Parkinson kaThixo - indlela mandundu ukuphazamiseka CNS, ikakhulu echaphazela nokusebenza kwenkqubo musculoskeletal. Ikakhulu eyenzeka ebudaleni (emva kweminyaka 70-80), kodwa kukwakho iimeko zesi sifo emva kweminyaka engama-40. kwedatha yeenkcukacha-manani zibonisa ukuba bonke abantu 500 ehlabathini ubunzima kwesi sifo.

Abantu abaninzi bacinga sifo Parkinson kunye Alzheimer-like. Kuzo zombini ezi meko ungekachatshazelwa othile kwinkqubo luvo, kodwa ke uphuhliso womatshini yahluke kakhulu. Kuba isifo i-Alzheimer luphawulwa ukuphazamiseka kwengqondo kwaye baphazamiseka advantageously musculoskeletal Parkinson.

komzimba yesifo

Izindululo for amanqaku uyaphendula CNS. Xa indoda nje ukuba bacinge malunga noko afuna ukuyenza, lo neuron sele ethumela umqondiso kuzo zonke iinkqubo eziza kuthatha inxaxheba kugwayimbo. Enye emacaleni uphawu ezifunyenweyo - le ganglia Uhlobo Lokuqala. Le nto eqinileyo ezimhlophe ngohlobo ezalathelwe uphuhliso zemithambo benza iintshukumo entsonkothileyo nzima. Umgangatho pulses ezosulela ngabo kuxhomekeke kwindlela uya kuba ezichanekileyo, ezikumgangatho ophezulu kunye inyathelo ngokukhawuleza.

Oku kulawula inkqubo ye-dopamine neurotransmitter. isifo Parkinson kaThixo kuchaphazela ezinye iindawo ganglia carcinomas, nto leyo Uhanjiso kakuhle neemvakalelo-luvo. Ukongeza, izigulane ephawulwe amanqanaba ukuhla dopamine, leyo inoxanduva inhibition abasisigxina Imiqondiso nedumbe excitatory. Ngenxa yoko, inxalenye yabo uthunyelwa ngqo kwizihlunu kudaleke nokuncipha kwabo. Yintoni ekwenza hypertonicity, nivuthulule rhoqo ombane explainable rhoqo esiqwini kwezihlunu.

oonobangela

uye ke lakudlula ixesha elaneleyo ukususela ngoko, njengoko iseti iimpawu baqalisa ukuba ozakuthathwa sisifo esahlukileyo. CNS ukuphazamiseka ndlela isebenza ngeendlela ezininzi kubonakala kwakubekwe kuphela, izifo ezithile Parkinson kaThixo. Yintoni na - oosonzululwazi uyazi, kwaye yiloo nto inegalelo ekwakhiweni kwayo ayaziwa. Esilindelekileyo kuphuhliso esi sifo iphenjelelwa:

• ukuguga - kukuhla zendalo inani iiseli zemithambo-luvo nokuvelisa dopamine;
• factor olilifa - ayiqinisekiswanga ngenzululwazi ubukho isakhi lwesifo Parkinson, kodwa-10% amatyala emthini usapho isalamane kunye zoxilongo efanayo;
• ukunxila elide (sesichengeni nesinyithi enzima, buthi, iyeza lokubulala izitshabalalisi);
• ukusetyenziswa neuroleptics (ukuncipha kwemveliso dopamine kwaye kungabangela izifo);
• nokulimala kobuchopho nethumba;
• uxinzelelo, ulale kakuhle nedayethi, ukungabikho kweevithamini;
• nezinye izifo.

Izinto ezibangela izifo Parkinson kunye unyango ixhomekeke ngqo kwi enye kwenye. Ugqirha uya kuqhubeka ukusuka kwinto yokuba kwabangela uphuhliso ezingaqhelekanga Uhanjiso neemvakalelo-luvo. unyango Umgangatho lwezinto ezenza ziya kunika iziphumo okulungileyo unyango yonke sifo.

iimpawu

Ulwazi Iimpawu zokuqala zesi sifo nga kunceda isigulo kwangethuba kunye nonyango, nto leyo eyandisa amathuba unyango kunye iminyaka yobomi. Le theyibhile ingezantsi iimpawu eziphambili kunye nohlobo kwazo;

Izigulane ukuqina Parkinson xa iintshukumo zakhe. Yona ipatheni uphawu iintlobo zabantu: iingalo igotywe iingalo kunye licinezelwe emzimbeni, umzimba uzimisele kancinane kwaye ubunzima yasiwa phambili, intloko yakhe kancinane nangengalo. Aluve Abokuhlunguzelelwa periodic amalungu omzimba, ubuso ezolileyo, swi nga ha phofula mintlhaveko.

Parkinson kaThixo isifo nobomi ekulindeleke ukuba

Enye le mibuzo imincili zezigulane kunye nezalamane zabo, "? Mingaphi iminyaka emva lokufunyaniswa sifo angaphila" Le iingcali Impendulo kukuba: "Xa isifo iphezulu kakhulu kwiminyaka yokuqala angalindela kunokuba saka." Izifundo zakutsha nje zibonisa ukuba Umyinge engama-7.4. Eli xesha elinye, nto leyo ekhaya kumntu avareji unesifo "Parkinson kaThixo".

Kwaye elindelekileyo yokuphila ibiza ekwenziwa ngayo izinto ingakhethi kuvavanywa kuphela ngokusekelwe yobudala abantu abaqala. Le wathandwa zokuqhubeka kuxhomekeke kwizinto ezininzi, nto leyo kule mihla, ngethamsanqa, ungenza baphenjelelwe:

• umgangatho unyango kunye nokhathalelo;
• izwe ohlala kulo;
• sifo ngexesha lokwaluka unyango.

Uphando oluqhutyiweyo apha UK, nithi ukuba izitshanguba of the central nervous system, kukhokelele kwiminyaka emalunga neminyaka engama-40, umlinganiselo yobomi sobude liselikho 39 iminyaka. Kubonakala ukuba, kungakhathaliseki nokuba ngaba esi sifo iphuhlisa, umntu abe nethuba elihle lokuphila ukuya neminyaka ubudala. Kakade ke, oku kunokwenzeka kuphela ukuba indlela yokuphila esempilweni kunye nonyango therapeutic ejoliswe njengengubo ukuqhubela phambili kwesifo.

isigaba yophuhliso

Isifo asivelanga esithubeni, ngokuthe ngcembe iqhubeka. isigaba ngasinye luphawulwa iimpawu ezithile. Ngokusekelwe uhlobo lwesifo Parkinson kaThixo, indlela unyango uzimisele. 6 ukwahlula izigaba zesifo:

1. Le yokuqala (zero) - akukho zimpawu, kodwa sele kubonakala waba ukuphazamiseka nokuxhaphaka ukulibala.
2. Lokuqala - bazoyise macala, imiqondiso sibuthathaka. Kweli nqanaba, bambalwa kakhulu abantu baye kugqirha.
3. Okwesibini - esi sifo luchaphazela imilenze, ukulungelelana kakuhle umzimba, kunzima isigulane ukuba ukulinganisela kwakhe.
4. Okwesithathu - kunzima ukuhamba ngaphandle kwenkxaso, lafa kwandisa.
5. Okwesine - kukunqongophala okupheleleyo ikhono lokwenza intshukumo zabo ukuhamba, kodwa walondoloza ubuchule ume ngaphandle kwenkxaso. Abagulayo kufuneka yinkathalelo ebalulekileyo kunye noncedo.
6. Okwesihlanu - umntu angavalelwa kulala, kukho ilahleko epheleleyo yolawulo kwenkqubo musculoskeletal.

Ngalinye amanqanaba yophuhliso sifo kufuna indlela ngamnye. Ukuba unayo nayiphi na iimpawu zokuqala kufuneka uqhagamshelane ngokukhawuleza kwagqirha. Unyango lwakwangoko kunceda zokoyisa isifo Parkinson, yaye iminyaka yobomi uya kunyuka izihlandlo eziliqela.

ekuxilongweni

Xa ubhekisela igqirha naliphi na inqanaba lophuhliso izifo unikwe kuxilonga, nto leyo inceda ukufumanisa isifo ngqo. Ugqirha uxhomekeke algorithm ilandelayo:

• uhlolo kunye nokuchongwa iimpawu engqina phambi parkinsonism;
• nokuzimisela yohlobo esi sifo: parkinsonism eziziisekondari kubangelwa isifo sentliziyo kunye ukonakala kwengqondo, okanye esizimeleyo;
• isiqinisekiso kwesifo ngokusekelwe data eqokelelweyo imbali yezonyango kunye elebhu kunye nezinye iinkqubo zonyango.

Kakhulu wayedla uxilongo mihla: CT, MRI, PET okanye emiselweyo uviwo iinqanawa Cerebral (REG, EEG).

Njengoko iimpawu ezithile kuvela ezibonisa engqina kwezihlunu, ixesha elide sifo kunye progression yayo. Umzekelo, flexion isixando kufuneka ikhatshwe ukuphumla ngoko nangoko izihlunu, kwaye isigulane, phezu koko, kukho cut zabo.

iindlela zonyango ekunyangeni izifo Parkinson kaThixo

Uxilongo ayikho asisoloko sithetha unyango ngoko nangoko. Oogqirha sokuvavanya ngeengozi kunye nobunzima, ixesha sifo kunye isantya progression yayo. Indlela ukunyanga isifo Parkinson kaThixo? ukusebenza therapeutic lusekelwe yokwamkela lwamayeza, ezo ezijoliswe ethintela imveliso dopamine kunye nezinto yayo ebulalayo. Kuba ezi iinjongo uthetha:

• umxholo dopamine, uhlobo okanye agonists ( "levodopa", "Lisuride", "Ropinirole" "Bromocriptine");
• uvimba enzyme isandla ekutshatyalalisweni dopamine (Mao kunye COMT inhibitors);
• ukuququzelela ukukhululwa woovimba neurotransmitter ( "Bemantan", "Amantadine");
• uvimba excitation ngokugqithisileyo zemithambo-luvo ( "Biperiden", Trihexyphenidyl, "" protsiklidina "" Memantadin ");
• neuroleptics, antihistamines, kunye nemithi yokunciphisa kunye relaxants kwezihlunu.

Kumanqanaba okuqala uluvo ngendlela yokuphatha amayeza Parkinson kaThixo, basoloko umlinganiswa ongqala ngqo kumntu omnye. Umzekelo, isitshixo i "L-dopa" igqalwa iziyobisi kakhulu kwaye ukhetha akukhathali isicelo sayo. Amanye amaqela iziyobisi (agonists, Mao inhibitors kunye COMT) athambe kwaye musa ukuba esi sifo ukuba inkqubela. Kuyinto ngenxa iziyobisi ezifana ngayo kunokwenzeka ukuba alibazise ukwamkela "Levodopa".

Unyango zikumanqanaba okugqibela

Kungakhathaliseki uhlobo sifo, kuphuhliso yayo kufika ixesha xa ulwaphulo ezi ayibuyiseki umva kwakhona, yaye anda kakhulu ngenani. ukusetyenziswa elide "Levodopa" iziyobisi (iminyaka malunga-5 okanye ngaphezulu) ekhokelela kuseko yokumelana neziphumo zayo. Kukho imfuneko yokwandisa iiyunithi umthamo, obuquka ezinye iingxaki.

unyango Nomonde of ekupheleni-sigaba yancitshiswa ukunciphisa ukuphazamiseka osezingqondweni, ukhathalelo lwempilo olusemgangathweni kunye zasekhaya. Esithathwa amayeza ezilawulwa imihla ngokuxhomekeke eziphilayo kunye nokusebenza asabela.

Iindlela zonyango steel

Surgery lunqabe kusetyenziswa kuphela kwiimeko apho unyango endala akanamandla. Olu tyando lwenziwa kwi ebuchotsheni: i thalamus kunye uthinte. Senziwe iindlela ezininzi impatho enjalo:

• ubuchopho basafunda Electrical - kubume ubuchopho yomguli laqalisa electrode abaqhagamshelwe kwi neurostimulator, i implantable phantsi ibele. Inkqubo kubamba Parkinson kaThixo. ingxelo entle malunga nokusebenza: imeko jikelele kuphucula, ithoni wayicola ukuqina, isifo siqhubeka kancinci.
• Thalamotomy - indlela oluyingozi, kodwa ke ngamanye amaxesha kuzisa iziphumo ezilungileyo abuyisele umsebenzi lwemoto kwenkqubo musculoskeletal. Ngaba intshabalalo izakhiwo ezithile thalamus.
• Abohlukeneyo of dopaminergic inyama - ndlela yokulinga, ngokusekelwe abohlukeneyo izinto kubalizi. Lukhuthaza kuqheleke imveliso dopamine kunye nokufunyanwa umsebenzi motor.

Surgery - indlela eze- ekunyangeni izifo Parkinson kaThixo. Naseluntwini lehlabathi izazinzulu ubusebenza kuphuhliso nokuphucula iindlela ezikhoyo yimpembelelo ezonakalisayo kunye ngendeb kwi ebuchotsheni.

Izincomo Alternative Medicine

Ukugcina umzimba kufuneka uqwalasele indlela yobomi, ukutshintsha ezinye imikhwa. Isigulane kufuneka ancame nobukhoboka, ukuseka amandla, ixesha elingakumbi lokuphumla kwaye hayi ukuba ukhathazeke ngokungeyomfuneko. Kwezonyango umzimba, fresh umoya kunye nobungcali umyalezo kwakhona akazange aphikisane ngemva.

Not Akuvunyelwe ukuzama kunye nonyango wesizwe Parkinson, olusekelwe phezu nokusetyenziswa kwezityalo ezingamayeza. Asimele silibale imfuneko ukuthatha amayeza: amayeza endalo kudlala indima exhasayo, kodwa hayi esingundoqo. Kuba unyango kusetyenziswa kwekalika, propolis, ihabile, lobulumko, Wort St. kaYohane. Baye neziphumo relaxant anticonvulsant kunye kwezihlunu.

isifo Parkinson, yaye kweminyaka yokuphila uxhomekeke ngqo kwi ubungqongqo izitshanguba ingqondo, ukuqhubela phambili isantya imeko yangoku isigulane. Ukufunyaniswa kwangoko kunye nonyango, njengoko umthetho, ukubonelela eminye iminyaka 20-30 yobomi.