Isifo Myeloproliferative: oonobangela, iimpawu, isifo

oonobangela Myeloproliferative sifo, iimpawu, une leyo eza kuxoxwa kamva, kwenza iqela uthi, wagaleleka kuyo umongo, kukho ukwanda kwemveliso ye thrombocytes, erythrocytes okanye leukocytes. Xa iyonke kukho ezintandathu iintlobo ezimbi.

Overview

Bone nomongo ngokuqhelekileyo wenza isizukulwana stem (ubuntwana) iiseli. Emva kwexesha ziya zikhula, babe ngokupheleleyo. Iseli stem inokuba njengesiqalo ukuyilwa kweentlobo ezimbini lwezinto: inani lymphoid kunye myeloid iiseli. iiseli bevuna na imifanekiso ukuze kwakhiwe leukocytes. Phakathi iziqalelo thotho myeloid ziveliswa:

• Erythrocytes. Bona mpilo kunye nezinye izondlo iindibaniso kwi Amalungu nezihlunu.
• Leukocytes. Ezi zinto banoxanduva inkcaso kunye nezinye izinto ezimbi ezosulelayo.
• Zegazi. Ezi seli abakukhusela ukopha, uhlobo egazi.

Ngaphambi kokuba inguqu ibe iiseli ezibomvu, iiseli ezimhlophe okanye zegazi, isiqu iiseli kufuneka ukuya kwizigaba eziliqela. Ukuba ikhona, isifo myeloproliferative, isixa esikhulu sezixhobo zokufunda uqale ukhandwa enye okanye ngaphezulu iintlobo iiseli kwakhiwa. ngezifo Ngokuqhelekileyo kancane kancane ngokwaneleyo kunye ukwandisa iziqalelo igazi kwemfuneko.

ngezigaba

Uhlobo okungenzeka isifo myeloproliferative kuxhomekeke kubungakanani erythrocytes, iiplatelets okanye leukocytes. Kwezinye iimeko, umzimba nto ukuzibhubhisa uphawu lweziqalelo iintlobo ezingaphezu kwesinye. Pathology wohlulwe:

• leukemia Chronic neutrophilic.
• Polycythemia.
• leukemia Chronic myelogenous.
• thrombocytopenia Kubalulekile.
• Idiopathic (chronic) myelofibrosis.
• leukemia Eosinophilic.

isigaba yezifo

isifo esinganyangekiyo myeloproliferative nga kuguqulwa ileukemia oyingozi. Le meko luphawulwa agqithisile iiseli ezimhlophe zegazi. isifo esinganyangekiyo myeloproliferative akanayo inkqubo mvelo ethile. amanyathelo therapeutic ixhomekeka kuhlobo ngezifo. Ngokuphathelele kwindlela, esi sifo myeloproliferative nga kwenzeka ngenye ngeendlela ezintathu:

• Ukuntshula kwezinye iithishu. Kulo mzekelo, umhlaza kwanwenwa olubiyele inxalenye esempilweni, bendibetha kubo.
• indlela Lymphogenous. isifo Myeloproliferative ingangena kwinkqubo emithanjeni nezitsha zalo athunyelwa kwezinye ancedisana amalungu.
• indlela Hematogenous. Iiseli yobubi ukungena kungena emithanjeni kunye imithambo kwalusa ancedisana amalungu.

Xa ukunwenwa iiseli ithumba, mhlawumbi zakha (eziziisekondari) ngamathumba ezintsha. Le nkqubo ibizwa ngokuba Ukudlulela. Secondary ukuya nangezilonda zaseprayimari, zezona uhlobo olufanayo lomhlaza. Umzekelo, kukho ukunwenwa iiseli leukemic apha ebuchotsheni. Kubonakele izinto ithumba. Bayibiza wegazi, hayi wobuchopho.

iimpawu zokugula

wenza njani isifo myeloproliferative? Iimpawu ezi zifo zilandelayo:

• ukwehla kobunzima, unesifo.
• Ukukhathala.
• Isisu ubuhlungu nemvo Ukwanda ukutya ukuzila. Last Bamqumbisa spleen eyandisiweyo (splentomegaliey).
• Ukuthambekela ukopha, bazigruzule okanye iimpawu thrombosis.
• ukwazi kwamehlo.
• ubuhlungu Joint, ukudumba, wamqumbisa samathambo gouty.
• Unkenteza ezindlebeni.
• Efakwe kwi ikota yesangqa lasekhohlo ongentla igxalaba esisu kunye lasekhohlo, nto leyo ngenxa yokukrala okanye iqhosha le udakada.

survey

Myeloproliferative igazi sifo zabonwa ngenxa lweziphumo zelebhu. Olu phando ibandakanya le misebenzi ilandelayo:

• Uviwo lwe isigulane. Kulo mzekelo, ingcali umisela imeko jikelele ibonisa iimpawu kwezimilo (ukudumba, umzekelo), kwakunye boniso, kwakungekho mntu usempilweni. Ugqirha ucela yempilo yesigulane, izifo kunye nemikhwa emibi, ukuyalela.
• Extended pat. Blood yesampulu ikhutshwa phandle ukuba:
  
  - inani zegazi kunye neeseli ezibomvu igazi;
  - ratio kunye nenani leukocytes;
  - izinga kwalo;
  - umthamo nekuhlala iiseli ezibomvu.

• Eskom kunye wamathambo biopsy. Ngexesha inkqubo, inaliti zamafu umngxuma yaziswa kwentamo okanye iliac ithambo. Le buqhinga ikuvumela ukuba ukuthatha isampulu lomongo wethambo kunye zomzimba ngokunjalo ngegazi. Le nto ke ancinwe ngemicroscope ubukho iiseli ezingaqhelekanga kuyo.
• Uhlalutyo Cytogenetic. Le nkqubo ikuvumela ukuba ukubona utshintsho kwi zofuzo.

Chronic isifo myeloproliferative: Treatment

Ukuza kuthi ga ngoku, kukho amayeza izifo ezininzi. yenye okanye enye indlela ekhethiweyo ngokuxhomekeke kwimeko yomguli kunye ezibonisa eziyelelene izifo myeloproliferative. Le unyango kuqhutywa umgangatho - bazibonakalisa ukuba yokusebenza, okanye zovavanyo. Le ndlela yesibini kukuba ukufunda ukusebenzisa iindlela ezintsha ezahlukeneyo.

phlebotomy

Le nkqubo ithatha igazi emthanjeni. Le nto ke wathumela ukuba uhlahlelo eqhelekileyo ezinto eziphilayo. Kwezinye iimeko, phlebotomy emiselweyo abaguli abafunyaniswe nesifo myeloproliferative. Unyango kulo mzekelo ngqo ukunciphisa inani erythrocytes.

zegazi apheresis

Le ndlela uyafana nalowo wangaphambili. Umahluko kukuba kukho into yenziwa ukushenxiswa zegazi extra besebenzisa izixhobo ezizodwa. Isigulane uthatha yegazi baluwela umahluli. Uphethe zegazi. "Nyibilikisa 'igazi emva isigulane.

igazi

Le nkqubo i ukutofelwa igazi. Kulo mzekelo kufakwe ezinye izinto. Ngokukodwa, isigulane endaweni iiseli zabo zatshatyalaliswa nezonakeleyo ufumana ukutofelwa iiseli ezimhlophe zegazi, iiseli ezibomvu neeplatelets.

chemotherapy

Le ndlela iquka ukusetyenziswa kweziyobisi cytotoxic. isenzo yabo sineenjongo ezingatshabalalisa iiseli ithumba okanye njengengubo ukukhula yamathumba. Ukuze isicelo ngomlomo, efakwa okanye intramuscular iziyobisi, izithako zabo esebenzayo ukugqobhoza kulo kwegazi, ukuphelisa izinto zophendlo lwezifo. Oku kubizwa ngokuba ichemotherapy systemic. ubuchule Regional yi intshayelelo kuthetha kungena emjelweni spinal, esichatshazelwa ilungu okanye umzimba kwisisu ngqo.

therapy radiation

Unyango lwenziwa usebenzisa rhoqo x-reyi okanye enye kwemitha. therapy Imitha ukufikelela kupheliswe olungagungqiyo iiseli thumba wehlise ukukhula yamathumba. Ukuziqhelisa, kukho iindidi ezimbini zonyango. Unyango radiation lwangaphandle ukungakhuseleki yunithi, ebekwe ecaleni isigulane. Xa inkqubo ukuzaliswa lwangaphakathi ikhutshwa phandle radioactive izinto iinaliti, catheters, iityhubhu, ezithi ke ngoko lesitofu ngqo kwi nethumba okanye ancedisana ibekwe ngeenxa zonke kuyo. Yeyiphi indlela iza kusetyenziswa ziingcali, kuxhomekeke iqondo yobubi yenkqubo. Izigulane uxilongwe myeloproliferative igazi sifo okufakwe, njengoko umthetho, indawo udakada.

Chemotherapy ne abohlukeneyo weeseli

Le ndlela kunyango isicelo kweziyobisi ngeedosi eziphezulu kunye kufakwe ochaphazelekayo antitumor isenzo iiseli ezintsha. izinto olungaqolanga zivela mali okanye isigulane kunye zibambene. Emva kokugqiba chemotherapy yaziswa umbandela yomzimba igcinwe. Innovations iiseli ziqala sivuthwe ukukhuthaza ukuyilwa iiseli ezintsha egazini.

sokubuyisa ixesha ekuphulukenwe

Emva kokuba unyango, isigulane kufuneka ubone rhoqo kugqirha wakho. Ukuvavanya ukusebenza unyango kusenokufuneka ukuba aqhube uthotho iinkqubo ezisetyenziswayo ngaphambili phambi kokuba baqeshwe. Ngokuhambelana kunye iziphumo, isigqibo lokuqhubekeka, ukuzaliswa okanye ukutshintsha irejimeni yonyango. Olunye uphando kufuneka luphindwe ngokuthe rhoqo, nokuba emva kokugqiba le khosi zonyango. Amvumela ukuba ukuhlola ifuthe lweziganeko ukubona likakade.