Igwele-ezifana fungi ze sodidi Candida

Ngoko ihlabathi ukuba ngamnye kuthi ingqongwe amawaka zizidalwa ezincinane. thina ngeliso lenyama abazibona, kodwa kungena adibane nazo zonke ngcaciso imfutshane. Abanye "obungabonakaliyo" kusinceda, abanye babulawa, kwakunye nabanye enokuzisa, yaye ububi kunye inzuzo. Igwele-ezifana fungi ze sodidi Candida nje iintsholongwane enjalo musa ukuthintela ukuba sihlale ngokonwaba ngonaphakade emva, kodwa kwiimeko ezithile baqalisa ukuba baziphathe ngamandla, ibangela candidiasis izifo okanye thrush. Ngenxa yokuba ezi zinto ziphilayo ayisoloko nabungozi, zibizwa ezingenelelayo. Total wafumanisa iintlobo 186 of fungi ze sodidi Candida, kodwa ke ingozi kweshumi ezimbini kuphela. Phezu kwabo kuya kuxutyushwa kweli nqaku.

Sodidi Candida fungi: iimpawu

Candida Igwele besive sodidi. Uninzi kweentlobo azinabungozi ngokupheleleyo size siphile emzimbeni ngundo iti kwi iyogurt, nezinye iimveliso zobisi, kwakunye kwisiqwenga zesisu womntu, ebonisa inxenye izihluma esempilweni ethunjini. Iintsholongwane ayiyo ye sodidi Candida na aerobic, oko kukuthi, unobomi esebenzayo phambi kwe-oksijini. Baya mbi iintlobo ezimbini - negwele kunye micellar. Xa Igwele ifungi blastospores setyhula okanye mbhoxo thomo, zande. Ifom micellar kweeseli ezinzwaneni elongate, ajike abe pseudomycelia. Ngokungafaniyo yinyaniso, akukho izahlulelo, kodwa kukho constriction. Bona ibekwe blastospores, ukwandisa terminal hlamidiospory kabini-ezilala. Ifom micellar of fungi ziyakwazi ukuba zizale.

Nezinye izidalwa fungi dimorphic ye sodidi Candida zahlukile kakhulu ukuba babe kumzimba inkosi yakhe ezimbini iifomu zawo, kodwa hayi ukutshintsha kuzo ngokuxhomekeke lobushushu kuma kulo.

Kwipropathi ebalulekileyo Candida - bayakwazi ijike maltose kunye iswekile.

isifo Candidiasis, ngokutsho kwizifundo lwakutshanje, unobangela malunga 20 iintlobo nomngundo, kwaye C.Albicans eziyingozi kakhulu (60%) kunye C.Tropicalis (20%). I-ntlobo 18 zabiwa ngokubanzi kunye nefuthe kangako kwi isehlo candidiasis abanayo.

INKCAZO ESIFUTSHANE species izifo

I-fungi ezininzi eziqhele wadibana ye sodidi Candida, ebizwa C.Albicans. zenethiwekhi zabo malunga 8 kwabali-10 Inkoliso yezi fungi ngenisa emzimbeni umntwana ekuzalweni aphile ngaphandle ephazamisayo, em- zomlomo, kuvuleke iminxunya namathumbu. Xa abafazi, ukuba ziyingxenye microflora lobufazi. Yile hlobo Candida kaninzi noxanduva ukwenzela iziganeko candidiasis.

Uhlobo lwesibini ibizwa ngokuba C.Tropicalis yingozi. Ezi fungi bakwazi ukungena egazini aze asebenzise ngayo ukuzalisa amalungu peripheral. izifundo kutshanje kutyhilwa inkalo yomsebenzi Candida C.Tropicalis ngokubambisana kunye marcescens Serratia kunye coli Escherichia, kwaye unobangela sifo Crohn kaThixo.

Akuxhaphakanga kakhulu, kodwa kucingelwa ukuba i-fungi ingozi sodidi kweentlobo Candida nagwele C.Krusei. Baya abanganyangekiyo ngamachiza "fluconazole", kusetyenziswa unyango losulelo fungal, ngoko ke kubalulekile ukuba umahluko uhlobo ngundo yayintsholongwane eyosulela ehlukumeza isigulane.

Iintsholongwane ayiyo Candida iintlobo C.Glabrata ingqalelo non-izifo. Zikhona kuphela kwifom Igwele kunye lokuyivelisa lolu kuphela. Kwiimeko ezininzi, Candida Glabrata zabonwa catheters wokuchama, apho it yakha biofilm obhityileyo. Le Umngundo ibangela candidiasis enzala.

Candida iintlobo C.Parapsilosis kaninzi iba unobangela nokudumba. Kuyinto olukwazi kusulela isilonda, ingakumbi xa izinto zangaphandle kuzo.

Iintlobo nomngundo kunye C.Rugosa C.Lusitaniae kunye nabanye sodidi Candida zinqabile kakhulu. Umzekelo, C.Lusitaniae kwixesha ukususela 1979 ukuya 1990 ibhaqwe kuphela izigulane ezingama-30.

Iindlela zosulelo

Phantsi kwemiqathango - fungi Igwele yayintsholongwane eyosulela kakhulu sodidi Candida ngethuba zazivelela ziye iindlela ezinceda ukuba ukukhokela ubukho ekumfimfitheni. Ukuba uyakwazi ukumelana ukuqanda ixesha elide futhi omisa. Faka umzimba womntu, zinokuba ukutya emdaka kakuhle alungiswa ngezandla ezimdaka kunye nezinye izinto, ezifana neenkowane C.Parapsilosis yosulele amanxeba kunye nokungena izinto zangaphandle, kuquka kwaye zintsholongwane izixhobo zonyango kunye neenkowane C.Glabrata kunye womchamo okanye catheters efakwa. Amaninzi ukuba bosulelwe yi nomngundo iintlobo C.Albicans, kwaye kwimizuzu yokuqala yobomi losana. Oku kwenzeka ngexesha lokuzalwa komntwana, ukuba oomama lobufazi nelinabemi nezi iintsholongwane. Kukho kwakhona intelekelelo yokuba C.Albicans ongena umzimba usana iselelona kwi ndiseyimbumba eqongeni, kuba amakhowa ngokuphindaphindiweyo kufunyanwa fluid. Ukuba umfazi ozalayo yinxalenye ipesenti encinane yabantu abangengabo abathwali amakhowa, usana lwakhe ngexesha minyaka yokuqala yobomi Ungazifumana ngokusebenzisa ingono, izinto zokudlala njalo njalo. Panic kuba oku kuyimfuneko, ngenxa yokuba Candida, kanye umzimba womkhosi wayo, ziphathe ngokuzola, nokuba ukumnceda, ukulawula ukukhula kwezinye kwamagciwane.

Xa fungi Candida usulelo lube nesifo

Umntu unokuba yenethiwekhi kweentsholongwane ubomi ngoxa usempilweni ngokupheleleyo. Iintsholongwane ayiyo ye sodidi Candida abe yayintsholongwane eyosulela kuphela xa ukwanda wabo ukuba unganweni yaye ungaxaki. izizathu:

- yokukhulelwa;

- izifo ezahlukeneyo;

- exacerbation kwezifo ezingapheliyo;

- hypothyroidism novithamini ngxaki;

- unyango lwexesha elide kunye antibiotics;

- corticosteroids;

- izifo hormone.

Esona sizathu ebangela candidiasis, a sifo ephantsi. Le meko yenzeka kwiimeko ezininzi, kuquka ukutya okungenazakha-mzimba, iimeko zokuphila amahlwempu, ntshikilelo rhoqo.

Ukongeza, ukukhula ngesiquphe nomngundo Candida lwenzeka xa izifo ezihamba zilandelayo:

- AIDS (okanye usulelo lwe-HIV);

- diabetes;

- tuberculosis;

- izifo zesisu;

- izifo kwenkqubo genitourinary;

- hypothyroidism;

- Ezinye izifo igazi;

- vaginosis.

izinto phathogenicity

Engqonge ngundo sodidi Candida na microns 2-5 kuphela, ngoko ke kuqwalaselwa kuphela phantsi ngemicroscope. Abo plenochki ezimhlophe okanye bulubhelu greyish ezimila agar okanye icwecwe ukuba obonakalayo kwimimandla echaphazelekayo lomzimba - oku ke amathanga lonke nomngundo, uniko manani, amakhulu amawaka ezincinane ngamnye. Kanye umkhosi ephilayo, imo fungi ze sodidi Candida? Microbiologists phando lwabonisa ukuba mushroom ngamnye izama ukuphuhlisa adhesion, oko kukuthi, kufutshane ukuya kuzibandakanya, omnye athi, sikhulele kwizisele abantu epithelial. It amagciwane ukulawula lula inowuthi omzimba amaxhoba awo, kwaye ngaphezulu ukuphazamiseka yakhe yonyango. Le nxalenye esebenzayo ye-mushroom iintlobo C.Albicans clutch. Xa phezu inwebu yangaphakathi, ihambelana kwi-100% yamatyala. iintlobo ezininzi mushroom nje C.Krusei. Kusenokwenzeka ukuba esisigxina, ngoko akukho usuleleko. Ukuncedisa fungi ingangena iiproteni komhlaba kunye neeproteni umphezulu, ezinye molekyuli, umz, polysaccharides kunye glycoproteins, kunye molecule e amathe emlonyeni. Ngokuqhelekileyo, Candida na glikogenofilami (glycogen ezifana), ngoko ngokufuthi colonizes esikule apho iqulethe ezininzi, umz, le isifo langasese kunye kwisisu ngomlomo. Xa kuthe Igwele fungi le sodidi Candida kwi-smear othatyathwe kwezi amalungu lwabonisa namathuba ephakamileyo yenza sifo imposiso-free.

Ngelo lokuqala fungi adhesion zezi fom igwele, kodwa ngokukhawuleza ngokutsha, ukwakha zixhobo elide (hyphae), kanti kulula ukungena kungena iiseli host ezonakeleyo phagocytosis of leukocytes ekuthanda kangako.

Ukuqinisa kunye inkosi, izinambuzane ebudeni bobomi babo umkhosi eziphilayo ekude iityhefu ezahlukeneyo:

- kandidotoksin (izenzo iiproteins kwi basophils kunye neeseli lwemasti kwaye ibangele pseudo-impendulo);

- iindidi 6 ityhefu ephantsi ezinto ubunzima (ukwanda permeability semithambo, uxinzelelo lwegazi asezantsi);

- zihlale lipid (reactions zasekuhlaleni leukocyte intsusa kungakhokelela yimbonakalo granulation inyama).

Candidiasis kubantwana

Njengoko sele kutshiwo ngentla apha, iintsana abanentsholongwane Candida nokuba esizalweni okanye ekuzalweni ngexesha sicatshulwa lomsele wokuzalwa. Kwixa elizayo, lo mkhuhlane ukufumana usana emlonyeni kunye pacifier kakubi kakubi, rattles, kunye mibele abosulelwe nonina. Iimpawu ukuba usana yaqashwa thrush, oku kulandelayo:

- ezimhlophe, cottage samasi-ezifana enamathela phezu ulwimi, phezu desenok kumphezulu ngaphakathi nezidlele;

- moodiness;

- ukwala ukutya.

Ngaphandle konyango, ngundo iyaqhubeka ukulungisa yaye kungekudala kubonakala phezu imilebe wosana.

Fungi kwe sodidi Candida ethunjini dysbiosis iimpawu zibonakale ezifana:

- isisu;

- silale;

- ubushushu;

- ukwehla kobunzima.

Urhudo kwiintsana kuyingozi kuba kukhokelela emzimbeni ngokukhawuleza, ngoko umntwana abagulayo ukuze esibhedlele. Kuphela esibhedlele kumnika kunye unyango eziyimfuneko (ithontsi) ukuthintela ukulahleka fluid.

Ukongeza iphecana zesisu kunye kwisisu ngomlomo, thrush kwiintsana angavela esikhumbeni. Kulo mzekelo, akukho omhlophe, kwaye amachokoza abomvu ngathi ilweyile angawokubhuda. Umntwana uba abangenazigqibo kakhulu njengoko naziphi erosions touch kumenze ukubandezeleka. Amaninzi, candidiasis cutaneous kwiintsana livela isondo apha emilenzeni, ezinqeni ubudoda. Kwakhokelwa ukujaduka ilweyile, ukuba amanabukeni elide kakhulu, ucoceko amahlwempu ezingafanelekanga (zokwenziwa, yaye uyadana) iimpahla.

Unyango lwe candidiasis bobusana

Ukuba fungi kwe sodidi inkqubo yayintsholongwane eyosulela Candida yaqala emlonyeni womntwana, unyango ngokuqhelekileyo luqhutywa ekuhlaleni. It iqulathe ekusetyenzweni iindawo apho kukho emhlophe umboniso, ucwangciso olukhethekileyo. Ngaphambili, oogqirha kuthiwa kuzithambisa umlomo usana kunye ngepeyinti eluhlaza. Eli yeza entle kakhulu, kodwa owomileyo yangaphakathi. Ngoku sebenzisa "Akriderm", "Fukortsin" solution yeboraksi kwi legliserina.

Nokuthintela kuyimfuneko kwiinyanga zokuqala yobomi grudnichka ubilise neengono kunye neebhotile, bazihlambe rattles. Umama kufuneka ukuphatha phambi kokunikeza neengono amachiza nokubola.

Xa iimpawu endleni yokupasa dysbiosis grudnichka kwi bakposev. Ekukholelwa ukuba fungi ze sodidi Candida kwi isitulo kwabantwana abangaphantsi kweminyaka iinyanga 12 mayibekho zixa zingagqithanga 103KOE / g, kunye kweenyanga ezili-12 kwi-mali ka 104KOE / g. Ukuba ixabiso kuyedlulwa, amisele iziyobisi ukubuyisela izilwanyana kunye nokomeleza amajoni omzimba.

Xa candidiasis isikhumba abachaphazelekayo iindawo yeoli nokubola waluqaba - nystatin, levorinovoy. Iluncedo kakhulu ukuze bahlambe umntwana emanzini kongezwe umhluzi yokulandelelana, calendula, chamomile. Zonke zokulala kunye amanabukeni kufuneka ayina, uze utshintshe ukucupha amaninzi ngokwaneleyo, hayi elinde ukuba ugcwalise yokuzaliswa.

Ukuba ezi unyango musa ukunceda, umntwana wakho uchitha uviwo ezongezelelweyo ukumisela unyango nokubola.

Candidiasis phakathi kwabafazi namadoda

Xa abadala, Candida ifungi unako, njengabantwana, ukosulela umlomo, nesikhumba namathumbu. Candidiasis esibonakaliswa emlonyeni caseous kwebala, ulwimi imincili, iintsini, inkalakahla, izidlele, kunye icala ngaphakathi kunye ubuhlungu. Ngamanye amaxesha ulcerate yangaphakathi. Candidiasis esikhumba luphawulwa ngamabala abomvu kwiindawo kwintshayelelo mkhuhlane (kwamakhwapha, phantsi amabele kwabasetyhini, kwi nasemiphakathweni, ubuncinane phantsi emadolweni). Ezi amabala nangenjinana udiliza, ngelixa ukufwaya ulcerate. Kodwa uninzi bonke abadala bayahlupheka ukusuka amalungu Candida womchamo. Abafazi fungi zakhele lobufazi kwaye womntu obhinqileyo, ngoko ke esi sifo kuthiwa vulvovaginitis. iimpawu zayo sikwinqanaba lokuqala ngolu hlobo lulandelayo:

- ezimhlophe (njenge amasi) ekubhobhozeni kusisi;

- ukurhawuzelela, hayi edlula, kodwa koko, emva ukucoca olukhulayo kunye kusasa;

- ezingemnandi ivumba yangaphantsi;

- Pain ngexesha ukulalana.

Uphawu kakhulu ukuxoxa - fungi ze sodidi Candida ngendlela smear othatyathwe lobufazi.

Ngaphandle konyango, mpawu zimbi. , Iintlungu kuphela ngexesha ocansini, kodwa xa echama nganye, fuku isifo lobufazi, ulcerate, ngobhobhozo uba mkhulu.

Xa abantu, usulelo kuthiwa Candida balanoposthitis. zimpawu:

- ulwabiwo uhlobo obufana yelungu ngokwesondo;

- ukurhawuzelela, ubuhlungu xa uchama;

- neentlobano ibuhlungu.

Ukongeza kule nkqubo genitourinary, Candida fungi ikutyela kwi imizimba zangaphandle zabantu. usulelo Nail ebizwa "neonika" kunye mqengqeleki prinogtevogo - "paronychia". Izizathu zezi zifo kunokuba hangnail, owenza izixhobo manicure abosulelekileyo.

Uhlalutyo phezu fungi ze sodidi Candida

Candidiasis umiselwe isekelwe kwiziphumo zezi zifundo:

- a smear evela kwisisu yomlomo okanye ikuku;

- ekulimeni;

- ELISA;

- PCR.

Ukongeza, ugqirha inokuyalela iimvavanyo umchamo negazi.

Ukuba uceba ukuthatha yezinkcwe evela kwilungu lobufazi kunye / okanye urethra, awuvumelekanga ukuba boyihlamba loo nto, kodwa achame kuphela iiyure ezi-2 phambi kokuba uthathe i-smear, hayi emva. Ukuba uceba ukuthatha yezinkcwe ephuma emlonyeni, oko aluvumelekanga ukucoca amazinyo.

Ngokudala ukusetyenziswa endleni, isikhohlela, umchamo, scrapings ukusuka kwiindawo achaphazelekileyo ulusu kunye ngenwebu yangaphakathi. Emva kweentsuku ezintathu, ufumane impendulo, ewe okanye hayi kule nesixhobo fungi ze sodidi Candida. KwiSithethe - i negative. Ukuba uvavanyo ukuqinisekisa ubukho ngundo, ukugqiba udidi yayo novakalelo amayeza.

Uhlalutyo ELISA kuthiwa immunoassay enzyme. Kuyanceda ukuba ukuchonga antibodies ngundo kunye umkhondo Dynamics inkqubo. Uphando Amanqaku kuba EIA a igazi emthanjeni. Ngokuqhelekileyo, ukuba lwenziwa kunye bakposeve.

Kucingwa uhlalutyo ichanekileyo PCR of oko kuthetha ntoni na Polymer-chain reaction ye DNA molecule ngulo mngundo. It ibhaqa ubukho pathogen nokuba lokuqala sifo. Izinto kuba PCR zezi zinomgutyulo yesikhohlela, igazi.

unyango

Ukuba isigulane wafumana fungi le sodidi Candida, unyango na amayeza. kwenkcazo Inside:

- "fluconazole".

- "Nizoral".

- "iDiflucan".

Ngaphandle wasebenzisa amafutha:

- "clotrimazole".

- "Sertokanazol".

- "Miconazole".

- Amakhandlela kunye pumafitsinom kunye nezinye iindlela zinqanda ukukhula ngundo. Baya linokukwenziwa aqholiweyo antiinflammatory.

Unyango abasetyhini abakhulelweyo ikhutshwa phandle kuphela ngokusebenzisa zangaphandle. Kuphela nje iimeko ezimbalwa elabelwe "Pumafitsin" ngomlomo.

Xa candidiasis enzala phecana na unyango omabini amaqabane ngesondo.

Ukongeza amachiza nokubola ezi iivithamini ezimiselweyo kunye nezinye iindlela, ukuxhasa amajoni omzimba.