"Chloride Suxamethonium": izinto inkcazelo, icala elingenzi nto-kunye nohlaziyo

Xa yezonyango, inani lamachiza ezifunekayo, umz, ukuba umzimba yomguli zibe kwimeko efunekayo ukuze imveliso uqhaqho. iinkqubo ezithile zifuna zamntu bawuphikisa ukuphumla elililo lwe izihlunu. Ukulungiselela le njongo, ukusetyenziswa idla iziyobisi "suxamethonium chloride" (Igama yorhwebo imveliso - "Listeon"). Eli chiza ubukhulu becala kusetyenziswa kumaziko zonyango ezikhethekileyo. Yintoni na le nto wesenzo imithi? Ngaba yingozi ukusebenzisa le mali? Yintoni kufuneka ilungiswe kunye ukusetyenziswa kweziyobisi "suxamethonium chloride"? Inkcazelo ukulungiswa ezinye iinkalo isicelo sayo eza kuxutyushwa kamva kweli nqaku.

isakhiwo

Eyona nto ephambili esebenzayo yokulungiselela uthathwa chloride suxamethonium. Kwakhona le medicament iquka amacandelo abangabancedani ezifana sodium chloride, ethylenediaminetetraacetic acid disodium ityuwa (Trilon B), okanye disodium edetate, namanzi ngenaliti.

release Form

"Suxamethonium chloride" zidla eziveliswa abenzi ngohlobo kwesisombululo (kokubini intramuscular kunye emthanjeni).

imiphumela kwemithi

medicament kujongwa depolarizing relaxant kwezihlunu. isenzo sayo mfutshane. I esebenzayo amacandelo beziyobisi ngempumelelo kuthintele ukudluliselwa neuromuscular.

Miorelaxation njalo kwenzeka ngokulandelelana enye, kuyimfuneko ukuba bakuthathele ingqalelo abasebenzi bezonyango. Ngoko ke, kuthathela ubudala kwezihlunu, ngakumbi ichaphazela izihlunu masticatory kunye nezihlunu neminwe, amehlo onke amalungu. Emva koko kwemisipha nokuphumla egqitha entanyeni, imisipha ngasemva, isisu, futhi imisipha. Latest basabela yintshukumo ichiza izihlunu intercostal kunye uvalo.

Ukuba ichiza nolwathi intramuscularly, oko ezizakubanesiphumo emva emibini - zone imizuzu, kwaye ukuba efakwa - emva nje kuphela. Ubuninzi kwemisipha zokwehlisa kwenzeka phakathi kwemizuzu emithathu emva ulawulo iziyobisi. Le isiphumo ihlala iminyaka emihlanu - imizuzu elishumi, ngokuxhomekeke idosi kweziyobisi.

Ichiza kubenge- isasazwe kwi plasma igazi neencindi extracellular kungekudala emva ulawulo isicombululo (ngaphandle ulawulo emthanjeni). Malunga namashumi alithoba ekhulwini hydrolyzed into, zibe choline okanye succinic acid. Phantsi kwento ethi uyondelelwano lwee- cholinesterase egazini igcinwe kwinqanaba ngokwaneleyo, nakwisiqingatha ubomi ichiza imizuzwana asithoba kuphela. Le into salawo ngokupheleleyo izintso (kubandakanywa pesenti ezilishumi - akhawunti ngesiqhelo).

Ubungqina obubonakalayo buxela

Ingqalelo ichiza elisetyenziswa kwiimeko xa kufuneka ukuba enze longenelelo ngoncedo ifuna epheleleyo zokwehlisa kwezihlunu. Iimeko ezinjalo ziquka bronchoscopy, endoscopy, yamophula abdominanlnye operation misa, ukuncitshiswa dislocations kunye endotracheal ekumfakeni.

umthamo

Iziyobisi "suxamethonium chloride" uyakwazi ufakwe yegazi kwaye intramuscularly (njengoko ukuthontsiza okanye bolus). Kuba indlela onjalo isicelo usebenzisa 0.1% nesisombululo kweziyobisi. ithamo Ukusebenza apho i chloride suxamethonium kunye iodide, oyingcali ngamnye wabelwa ngokungqinelana iimpawu ngamnye yomguli ethile, yaye ngokuqhelekileyo, xa kubhalwa yegazi zisukela milligrams 0.1 ukuya 2 kilogram nganye, kwaye intramuscular - ukususela-3 ukuya micrograms 4 nganye kg. In lonke ikhondo unyango ngumthamo opheleleyo izinto abafanele ngaphezu micrograms alikhulu elinamanci mahlanu.

Izimo

Ezinye izigulane kuyo nayiphi na imeko kwenziwa amalungiselelo "suxamethonium chloride". Imiyalelo zokusetyenziswa ichiza ngokwezi Izimo zilandelayo ngokusebenzisa ichiza: hypersensitivity ngamnye nayiphi na izithako ye medicament, myasthenia gravis, isifuba inyumoniya, engile-ukuvalwa neglaucoma, nokudumba yemiphunga, hyperkalemia, nokushisa onobungozi, insufficiency etsolo hepatic, naso kunye dystrophic myotonia, ukunqongophala cholinesterase, ukuba uneDuchenne muscular dystrophy, iliso kukwenzakala ngoomatshini. Kwakhona ingqalelo azivunyelwa ngokusebenzisa ichiza kubantwana abangaphantsi konyaka omnye yaye amabhinqa ngexesha nokuzala okanye lokuncancisa.

imiphumela emibi

Kwiimeko ezinqabe kakhulu, "suxamethonium chloride" (Solution for isitofu) kunokubangela eziliqela iimpawu kabi kwiinkqubo zomzimba ezahlukeneyo. Phakathi kwezi iintlobo negazi lakho (umz, bronchospasm kunye nokothuka anaphylactic), ukushwabana izihlunu zemiphunga (kwenzeka xa kukho ukuphazamiseka genetic ukuyilwa serum cholinesterase), arrhythmia, myalgia, ifiva, bradycardia, hyperkalemia, hypersalivation, ukothuka cardiogenic, yandisa uxinzelelo lwegazi, abanala makhwiniba Uhanjiso, ukwanda koxinzelelo intraocular. Ukuze siphephe iingxaki ngentla kubalulekile ukulandela ngokungqongqo iingcebiso malunga nokusetyenziswa ichiza "suxamethonium chloride." analogue Drug (ubuncinane ezinye zazo) zineziphumo ebezingalindelekanga ezimbalwa. Ngoko ke, maxa wambi bekuya kuba sengqiqweni ukuba isicelo oko kubo.

libanda

Kwimeko yokudlula idosi elingenzi nto okanye ngabom kucetyiswa Inokwenzeka eminye imiphumo engathandekiyo umguli. Kuyingozi kakhulu kwezi ukuyekwa kwawo ukuphefumla. Kulo mzekelo ngaphandle koncedo iingcali engenako ukwenza ngenye indlela, kungakhokelela ekufeni. Ufuna umoya engxamisekileyo. Ngamanye amaxesha level cholinesterase serum lwehla. Ezinye iingcali Siyaleza ukunyanga le meko okanye ukutofelwa igazi elitsha, nto leyo edla ekhuselekileyo drug-ethutyana.

imiyalelo ezizodwa

Kuyanconywa ukuba ukuqalisa ezikumgangatho ophezulu non-depolarizing relaxants kwezihlunu umzuzu phambi kokuba ulawulo iziyobisi "suxamethonium chloride." Inkcazelo izinto iqulethe ulwazi intsebenziswano enjalo ishenxisa umngcipheko sophuhliso kweziveliso ze-myalgia kunye izihlunu zomzimba. Kubalulekile ukuba usebenzise ichiza kuphela kumasebe ezikhethekileyo amaziko onyango, kuxhomekeke ekufumanekeni izixhobo eziyimfuneko (kubandakanywa izixhobo yokuphefumla ngumntu) kunye nabasebenzi abanobuchule nako ukusebenzisa kakuhle le ndlela nokwenza izigqibo kwiimeko uxinezeleko. Ekubeni isicelo ingqalelo iindlela kunokubangela bradycardia nomonde, kucetyiswa ukuba kungafundiswa ichiza kwisigulana "atropine" ngaphambi kokuba ukusetyenziswa "suxamethonium chloride".

Ngaba zidityaniswe nezinye imithi

Xa usebenzisa ezinye amayeza ngexesha elinye ingqalelo ichiza kufuneka sinikele ingqalelo ingaba intsebenziswano enjalo uvumelekile. "Suxamethonium chloride" umyalelo manual alukho ukusebenzisa ngaxeshanye kunye antimiastenicheskimi amalungiselelo kunciphisa nje ngokubonakalayo impumelelo yezenzo zabo. medicament ithatyathwa kwakhona iphucula iziphumo zoxubo of glycosides. Kuyo nayiphi na imeko ayikwazi ingasetyenziswa "chloride suxamethonium" ngaxeshanye igazi, njengoko ingqondo haydrolisis reaction, naziphi iimveliso igazi, izisombululo kwealkali kunye nezisombululo ze-barbiturates (ikhuthaza kwenze).

Ifuthe kwi ukukwazi ingqalelo (ukuqhuba kunye neendlela ezintsonkothileyo)

"Suxamethonium chloride" inempembelelo ebalulekileyo uyakwazi ukuqwalasela nokulondoloza ingqalelo. Oku kuthetha ukuba ukuze uphephe iingozi ukuphepha ukuqhuba nayiphi na eminye imisebenzi ziyingozi isoyikiso kubomi babantu kunye nempilo kwaye zifuna yoxinaniso aphezulu abasabela ngokukhawuleza kwaye ekhawulezileyo kwezigqibo ngomhla wokuqala emva kokupheliswa ichiza ingqalelo.

iimeko Ukugcinwa ezikhabhathini

Store "suxamethonium chloride" kuba phantsi kweemeko ezichazwe ngokungqongqo. Oko kukuthi, kwiqondo lobushushu yokugcina kufuneka lufikelela ezimbini ukuya kwezisibhozo degrees Celsius. Ichiza kufuneka zibekwe ngaphandle kwendawo ekhoyo ukuze abantwana. Ubomi eliphezulu lokugcinwa kwezinto ichiza yiminyaka emithathu ukususela kumhla wokwenziwa. Emva kweli thuba ukusetyenziswa ichiza akunconywa, kuba kulo mzekelo ithe iipropati yalo encedayo kwaye kunokuba yingozi umguli.

ukhuseleko Nomonde, ukhuseleko ubomi bakhe - kuba luxanduva noogqirha bazibandakanya ngonyango. Ngoko ke, kubalulekile ukuba iinkokheli amaziko onyango ngenyameko ukuba abasebenzi kula maziko abanolwazi isicelo kweziyobisi, iziphumo ebezingalindelekanga ezi mali, iindlela ukuphelisa naziphi basabele ezibi. Ngokufanayo, abasebenzi esibhedlele kufuneka babe nalo ulwazi nezakhono eziyimfuneko ukuze asebenzise ngokufanelekileyo izixhobo ezikhoyo ukuba ungagcina ubomi umguli. Oku kusebenza ngokukodwa ukuba amalungiselelo ziziphumo ebezingalindelekanga ogama bazo emngciphekweni nokuqalisa ukufa. Kubalulekile ukuba eli qela iziyobisi ziquka "suxamethonium chloride." Ngoko ke, kufuneka isetyenziswe kuphela xa kuthe ngexesha inkqubo kukho iingcali abanobuchule unako ukusebenzisa i mpilo. Oku kunokuba yimfuneko xa ukusabela kwicala ezifana ukubanjwa sokuphefumla. Kulo mzekelo, ulungelelwaniso izenzo oogqirha kunye nobuchule lwabo ngobuchule iya kuba yimiba ebalulekileyo ukuba kubonwe ukuba ngaba isigulane uya kusinda.

oogqirha Ngamanye amaxesha ngenxa yezizathu ezithile (ukuba kukho ezinye Izimo) isigqibo ukusebenzisa i relaxant imisipha - analog "suxamethonium chloride '(umzekelo," Ditilin "ungenako isicelo kuphela xa kukho glaucoma). Kubalulekile ukuba uthembe uluvo anegunya leengcali kulo mba. Ngoko ke, kufuneka uqiniseke ngesakhono lobungcali oogqirha nabo nawe sebenzisana.

Ngaphambi kokuba uphume ngokwakalokunje ukuqulunqwa bafanele bafunde bonke ngalo mbandela "suxamethonium chloride": zorhwebo igama, analogs, Izimo, kunokwenzeka imiphumela, nokusetyenziswa, kunye ezinconywayo balawule. Isigulana kufuneka ufunde iintambo koko uhlobo amayeza waphatha. "Listenon" ( "chloride suxamethonium") - igama yorhwebo iyeza umbuzo. Ngoko ke, xa uve imilebe eli gama ugqirha, uya kuba uyazi kakuhle ukuba uya kwenza emzimbeni wakho. Olu lwazi kuyimfuneko ukuze uphephe ukubeka ubomi babo esichengeni ngokungeyomfuneko. Kubalulekile ukuba ube baqaphele ukuba yintoni amayeza kuwe ebiqaliswe unyango.

Themba impilo yakho kuphela iingcali, khetha unyango mgangatho uphezulu kwaye imveliso egqwesileyo! Thatha nokuzikhathalela wena!