Ichiza 'MIG 400', imiyalelo ukusetyenziswa, imiphumela emibi

"MIG 400" non-steroidal nechiza elichasene-ukudumba. Le into esebenzayo i ibuprofen - yemvelaphi propionic acid iye antipyretic, iintlungu, isiphumo antiinflammatory, olwenzeka xa non-uyakhetha Cox kwafa - 1 no-2, kunye neziphumo inhibitory kwi prostanglandinov yokuqaphela.

Isiphumo ichiza njengoko iintlungu akunanto yakwenza uhlobo ezidakumbisayo, iye ubucaka ubuninzi ziintlungu nokudumba ehamba. Antiagregatnaya umsebenzi uphawu ibuprofen, kwakunye namanye amachiza non-steroidal.

iziyobisi Ifumaneka kwi ngohlobo amacwecwe ezimile elimbhoxo emhlophe. Tablets "MIG 400" isale ukuba ingozi indlela amabini babebhala "E" macala omabini. Ibuprofen tablet nganye 400 mg, ngaphandle koku kukho aids ekulungiseleleni "MIG 400", umyalelo ebonisa umxholo magnesium stearate, cornstarch, colloidal lesilicon dioxide, sodium carboxymethyl istatshi. Iqokobhe sinezi zixhobo zilandelayo: povidone K30, hypromellose, macrogol 4000, titanium dioxide.

pharmacokinetics Ukuqwalasela kuthetha kuthiwe ukuba kukho ukufakwa iziyobisi ngabo iphecana zesisu "MIG 400", amanqaku umyalelo nokuqulethileyo eliphezulu emzimbeni emva kokungenisa ngokusebenzisa ichiza 2 iyure iphawulwa 99% njengesibophelelo kwi iiproteni plasma, kulwelo lwamalunga zahanjiswa ngesantya esiphantsi plasma, amanqaku ezifanayo Ukuveliswa.

Le kinetics of kukhuthaza ibuprofen lunezigaba ezibini: ezona yure zininzi zisi-3 ukusuka plasma, umchamo kunye inyongo - malunga ne-1% ingaguqukanga.

Kukho imiqondiso emininzi ichiza "Grant 400", ingxelo ithi meko zilandelayo:

- bamazinyo, intloko ebuhlungu;

- neuralgia;

- migraine;

- umkhuhlane kunye njengomkhuhlane;

- joint, iintlungu kwezihlunu.

Thaca uluhlu oluneenkcukacha zeziphumo ebezingalindelekanga ichiza "Grant 400", umyalelo usinika inkcazelo eneenkcukacha zalo kwangokwaloo isiphumo kwiisistim umzimba ngamnye.

Inkqubo sokugaya: heartburn, nesisu esibuhlungu, ukugabha, ukuqhina kunye sorhudo, flatulence, kunqabile wabona kome kunye kwinwebu le inwebu imazi ibonakalisa emlonyeni.

isixokelelwano sokuphefumla: bronchospasm kwakunye nokubamba-bamba umphefumlo.

nemithambo yegazi: tachycardia, ukusilela intliziyo, noxinzelelo lwegazi.

Iimvakalelo: ukungaboni, ilahleko ukuva, umonakalo le luvo optic (ityhefu), conjunctivitis.

CNS: intloko ebuhlungu, ixhala, ukudakumba, ukudideka, ukozela and ugwayi;

Kunye nezigulo lunokwenzeka kwinkqubo wokuchama ngexesha kokungenisa "MIG 400", ingxelo ulumkisa ithuba Ngokuzimela kunye ukusilela etsolo kwezintso, nokudumba kunye nephritis komzimba.

Kusenokubakho ezinye ziyabagulisa ekunyangeni iziyobisi "MIG 400", inkcazo kwi myalelo iquka nokuthintela kokuvela kwamaqhakuvana eluswini, pruritus, nokuthimliswa uyalisa kunye anaphylaxis.

Xa umlinganiselo ophezulu kunye nokusetyenziswa elide ichiza "Grant 400" umyalelo ulumkisa nxamnye eyayichasene umsebenzi olubonakalayo, iintlobo ezahlukeneyo ukopha (zesibeleko, emathunjini, hemorrhoid), kwakunye kukuvela izilonda zesisu.

Xa ukhetha unyango for "Grant 400" ye ichiza kufuneka balumke, kuba lineqela Izimo:

- izifo wokugaya;

- ukopha ezahlukeneyo;

- "aspirin triad";

- Abantwana abangaphantsi kweminyaka eli-12;

- ukukhulelwa kunye ngexesha zisanyisa;

- hypersensitivity ku ibuprofen;

kufuneka bathabathe inkathalo enkulu xa:

- BP;

- ebudaleni;

- ukusilela intliziyo;

- besisu, gastritis, enteritis;

- ukusilela - isibindi, intso;

- isifo isilonda Peptic kunye ukuqina.

ukuchuma Female iqaphele nefuthe elibi ichiza, oko kucetyiswa ukusetyenziswa "MIG 400" kwabasetyhini uceba ukukhulelwa.

Le umthamo ichiza uzimisele ngamnye, ngokuqhelekileyo ukuya ku-200 mg ngosuku abadala, imfuneko yokwandisa ixesha imithi kuyimfuneko ukuba adibane yincutshe.