"Chloramphenicol" - wamehlo. Imiyalelo yokusebenzisa

Kunye nezifo eye badla ukusebenzisa iziyobisi "Chloramphenicol". Ngokuba amehlo yenye yezona ndlela zisebenzayo igalelo ukoyisa intshukumo ezincinane eziyingozi. Uwisa equlathe 0.25% nesisombululo chloramphenicol, leyo yeyona nto iphambili ebonakalayo ichiza. Chloramphenicol idla eziveliswa kubavelisi ezineengqayi equlathe ml-5 into esebenzayo inxaxheba iphakheji mfumba nayo cap isibeki.

Drug "Chloramphenicol" (wamehlo) umyalelo ichaza nje zintsholongwane enokusetyenziswa ekunyangeni uluhlu olubanzi izifo. It has umsebenzi elwa.

Chloramphenicol uye iipropati apho zinika isiphumo bacteriostatic kunye nomsebenzi ophezulu ichiza ngokuchasene inani iintsholongwane Igram-akhabayo kunye navumelanayo-Igram: Staphylococcus spp, Neisseria gonorrhoeae, Shigella spp .. kunye nabanye. Le into Umsebenzi nxamnye Ngeentlobo kwaye ngokwesiqhelo abanganyangekiyo penicillins. Kwelinye icala, uxhathiso ezincinane yingozi chloramphenicol kwakheka ngokucothayo kakhulu.

Iimpawu pharmacokinetic beziyobisi "Chloramphenicol" (wamehlo) umyalelo luphawu ngolu hlobo lulandelayo. Xa efumana amacandelo bakhe iziyobisi ngokukhawuleza kwaye phantse ngokupheleleyo etsalwe iphecana zesisu. Ngaphezu koko, bioavailability yayo yi-80%. Eli chiza ubuchule kuthunyelwa ngokukhawuleza emzimbeni. Inqanaba chloramphenicol iyabophelela kwiiproteni plasma 50-60% kunye metabolization layo esibindini. isiqingatha ubomi ichiza engundoqo into esebenzayo imalunga 1.5-3.5 iiyure, yaye ngokukhethekayo kwenziwe zinomgutyulo kwi yokuchama.

Ichiza "Chloramphenicol" (wamehlo) ingxelo icebisa ukuba xa kuthe kwezifo ezosulelayo kunye ukudumba okubangelwa amagciwane iso chloramphenicol. Oku, ngaphezu kwabo bonke, yicesina, segazi, unkonkonko, samehlo. iziyobisi esebenzayo kwi unyango yinyumoniya, meningitis kunye nezinye izilonda ezosulelayo.

Xa unyango izilonda suppurative ulusu, amathumba, izilonda trophic nokutsha, njengoko umthetho, ichiza esetyenziswa njenge-arhente zangaphandle. Kuba kweziyobisi mlonyeni kubonisiwe ukuba unyango lwezifo ocular arhabaxa.

Xa kutyunjwa ichiza kucetyiswa ukuba irejimeni balawule ngamnye. Ukuze abadala, umthamo we lwemithi mg 500 izihlandlo ezithathu-ezine ulwamkelo usuku olunye. Ngokuba abantwana kucetyiswa ukuba kusetyenziswe enomahluko, ngokuxhomekeke ubunzima umntwana kunye nobudala.

Ukuze abantwana ukuya kwiminyaka-3, ithamo elicetyiswayo yi 15 mg ngamnye 1 kg ubunzima bomzimba, ngokuba abantwana abaneminyaka emithathu ukuya esibhozo iminyaka - 150-200 mg, nabantwana abadala, iidosi 200-400 mg. Kuzo zonke iimeko, amayeza kufuneka kuthathwe izihlandlo ezithathu okanye ezine kwiintsuku 7-10.

Xa isicelo isicelo ngokwemixholo imithi izikhuseli igozi okanye ngqo kwi ndawo. Tubal kulo mzekelo zenziwa emva kwesithuba seentsuku 1-3.

Chloramphenicol (wamehlo) isikhokelo uncoma ukusetyenziswa unyango lwezifo lwamehlo kwi kwirejimeni entsonkothileyo nezinyangayo.

Eli chiza kunokubangela iziphumo ebezingalindelekanga. Khokela ikhomba ukuba amathuba lubandakanywe nezenzo igazi aplastic, isicaphucaphu, ukugabha, zinako uko- yintloko ezisisigxina. Kwiimeko ezinqabe kakhulu, kukho bedidekile, ingqondo, nemibono ezahlukeneyo, nto leyo eyabangela wamehlo "Chloramphenicol". Izimvo lezigulane wathabatha ichiza, esithi ngexesha ulwamkelo zingenzeka irhashalala kunye nezinye ezenzeka ngaphandle.

Musa ukuthatha amayeza kubantu abathe kokufunyaniswa izifo egazini kunye ulusu, abasetyhini abakhulelweyo kunye nabantwana ukuya kwiminyaka emithathu.

singakhankanya ngokukhethekileyo kufuneka balumke xa ukusetyenziswa kweziyobisi kubaguli abaye sessions unyango phambi amachiza cytotoxic kunye neeseshoni radiotherapy.

Ukusetyenziswa ngaxeshanye penicillin chloramphenicol buphazamisana nesenzo sabo bactericidal.