Urea. UNorma noonobangela ezinxaxhileyo.

Urea yimveliso protein yokubola. Xa deamination zisabela asidi acid ukuvelisa ammonia. Ukwenzela ukunciphisa zinetyhefu yayo yokungenelela, iya kuhlanganiswa kwi urea esibindini. Urea - a elisezantsi eziphilayo ubunzima compound, ngesisa edlula inwebu iseli iiseli ezibomvu kunye namaziko parenchymal. Nangona isibakala sokuba urea ngokwayo ion ephantsi-ezingenabungozi, ityhefu kodwa potassium engapheliyo ngayo, kunye nezakhi guanidine. Kungenxa yoko le nto umzimba womntu kubalulekile ngokwaneleyo ukuba igcinwe ngokusisigxina kwinqanaba eyimfuneko urea. Udidi Umxholo yayo ixhomekeke ubudala umntu, ibe ubonise uhlalutyo.

Urea - into esebenzayo osmotic, ngoko olwenzeka yayo ngokugqithiseleyo kunokukhokelela ekweneni nezihlunu amalungu parenchymal, inkqubo luvo, izihlunu ongama le myocardium.

Ukuze kubonwe kakuhle indlela ifowuni isebenza glomerular kidney, oko ifundwe inqanaba, apho plasma bagxila urea. Udidi lwesiqulatho kwayo le serum kufuneka 1,8-7,5 mmol / l. Ngelo xesha linye izinga eliphantsi inokuba okufana abantwana abangaphantsi kweminyaka eli-14, yaye liphezulu - abantu abadala, ogama yobudala ufikelela kwiminyaka engama-60. Kwiintsana le isalathisi kufuneka ngokubanzi ngaphantsi kwe 4.3 kungabi ngaphantsi kwe 1.4 mmol / l.

Ukuze ubone uyondelelwano lwee- urea ucazululo zengqo- igazi. Somfanekiso epheleleyo, kunye urea kwakhona ukulinganisw isiqulatho creatine. Ukuba, kwiziphumo wohlalutyo, urea landiswa, ngoko eli imeko kuthiwa uremia. Amaninzi oko kukhatshwa yi syndrome ngokwezonyango eyodwa ukunxila. Urea iveliswa ekwandeni izixa ngexesha ithi catabolic ngokusetyenziswa ngokugqithisileyo kwiproteni, kunye nokwenziwa kweziyi kunye acid emva ukopha esiswini. I-plasma lwee- ukunyuka urea ngenxa emzimbeni ngenxa awongezelelekileyo ukufakwa isixando ukuya tubules zezintso. Phakathi izifo kukhokelela ekwandeni kumanqanaba urea, ezinokuhlelwa ngolu hlobo lulandelayo:

• Amyloidosis, kakuhle kwezintso, pyelonephritis, glomerulonephritis, isifo sezintso ;
• flow umchamo engaqhelekanga okanye patency abaziintsizana womchamo;
• yamathumba okubulalayo wegazi;
• Ukungaphumeleli Heart;
• ukopha;
• iposi engabalulekanga;
• wamathumbu kokuphazamiseka;
• fever;
• Burns, okanye kukothuka;
• emzimbeni;
• cachexia;

Kukho kwakhona imeko komzimba, xa ukunyuka iqondo, nto leyo buzinze kwi urea egazini. Ummiselo inqanaba zalo ezifunekayo ukuze emakugqithwe ngenxa imithambo rhoqo ezikhathazayo.

Yandisa umxholo urea kwaye usebenzise iziyobisi ezithile. Phakathi kwabo ukuze kuchazwe ezifana phenylbutazone, steroid, aldomet, dopegit, Rauwolfia sezakhi, amalungiselelo isinyithi, kunye neziyobisi nephrotoxic.

Ngenxa yoko, uvavanyo lwegazi ingafunyanwa ukuba urea lifinyele. Nangona kunjalo, oku kwenzeka kunqabile kakhulu. Oku kwenzeka kakhulu amaninzi kwiimeko apho ukuhlukunyezwa umsebenzi zokwenziwa of kwesibindi, ukuba isigulane iwasebenzisa imali encinci protini. Ukumqumbisa ukuhla kumanqanaba urea yegazi ingaba izifo ezifana kwesibindi, ukuminxeka isiqaqa hepatic, hyperhydration, acromegaly, ukutyhefa ngu iarseniki okanye phosphorus, kwakunye ngurhulumente emva dialysis. Kwinqanaba komzimba ukuze lincitshiswe ngexesha lokukhulelwa urea. KwiSithethe eyavela egazini ngeli xesha liyehla. Isizathu sokuba ekunciphiseni urea nako ukutya okanye indlala. Yiyo loo nto kufuneka indlela ilungelo yokudla.