Ukusekwa wabonakala kuqala ehlabathini ukuba ukuphelisa uhlobo II seswekile

Nangona Kucingelwa ukuba Type 2 diabetes iphenjelelwa yemfuza babantu, abaphengululi bakholelwa ukuba uphuhliso walo enxulumene kakhulu ukutya kakuhle kunye nokutyeba ixesha elide, ingakumbi ebudaleni. Le injeke bengakwazi ukukhupha insulin ngokwaneleyo okanye iiseli zomzimba nje akaphenduli kuyo, nto leyo ekhokelela ukuba amazinga aphezulu ngokuyingozi iswekile yegazi.

Sesona sisombululo zizazinzulu American

Le meko ke yaziwa ngokuba ukunganyangeki insulin, kwaye okwangoku akukho ndlela zonyango ukunyanga kuyo. Noko ke, ichiza elitsha program iveliswe liqela oososayensi e University of California, kungaba idabi yokwenene kule nkalo.

Ngokutsho lowu New Scientist, idosi yemihla ngemihla ichiza, zona zashunyayelwayo kwindalo iimpuku kunye nokumelana insulin, owaba nako ukubahlangula kule meko. Oku kunjalo yokuqala ehlabathini, xa ichiza ekwazi ngempumelelo "unyango" diabetes yohlobo yesibini.

Yintoni ebangela ukumelana insulin

Iqela lophando kucingelwa ukuba uxanduva lokuqinisekisa ukuba ukuziziliza insulin yaba transcriptase ethile eyaziwa ngokuba LMPTP (eliphantsi ezinto protein weight tyrosine phosphatase). Izakufunyanwa esibindini, yaye, kuyabonakala ukuba, oko lisebenzisana kunye iiseli ukuze abanganyangekiyo ubukho insulin.

Ukusebenzisa ichiza elitsha ukuba ilungiselelwe ngokukodwa ukuba iyaluthintela uphuhliso LMPTP, izazinzulu babecinga ukuba iya kuvumela iiseli receptor insulin "funda" kwakhona ukuphendula insulin ngokuqhelekileyo. Ukuze uyolo lwabo, bafumana ukuba banyanisile.

"Iziphumo zethu zibonisa ukuba LMPTP yeyona nto ephambili yokuxhathisa insulin, nokuba inhibitors kule transcriptase ethile kuya kuba luncedo ukuba unyango seswekile uhlobo sinwenwa II", - ". Nature" Uthe iqela kwisifundo epapashwe kulindixesha

Luyaqhubeka lichiza entsha mpuku

Ngenxa yesi sifundo, ichiza laye ngomlomo yenziwa mpuku eziliqela elebhu. Ekuqaleni, ukuba wadliswa kunye namanqatha eziphakamileyo kakhulu, ngoko ke kuphuhliswa ukutyeba seswekile lohlobo yesibini.

Ngelo xesha linye yeempuku akazange nayo nayiphi na iziphumo ebezingalindelekanga ezivela ichiza elitsha. iiseli zabo kwakhona waqala ukuba uyiphendule ubukho insulin kunye iswekile yegazi amanqanaba lehla laya eqhelekileyo phakathi inyanga.

Inyathelo elilandelayo kukuba ingaba ichiza kuyimfuneko ukukhangela ekhuselekileyo ukusetyenziswa lingo lwezonyango ebantwini, yaye ngoku kuba kanye ngexesha elifanelekileyo.

Imbangela yokufa

Isifo seswekile, ingakumbi lohlobo yesibini iya kuba wesixhenxe ezinobangela ukufa ehlabathini lonke ngo-2030, njengoko izinga ukutyeba liqhubeka nokwanda, ngelixa inani iSifo ukuhla landa ngesantya breakneck.

Inani labantu nokubandezeleka kulo meko, kunyuke nge-390 ekhulwini kule minyaka ingamashumi amathathu inesiqingatha idlulileyo, kwaye kungoku nje kukho iindlela kuphela okudambisa iimpawu okanye gqiba sifo, kodwa hayi wabaphilisa. Mhlawumbi ichiza elitsha ekugcineni kuyitshintsha le meko.