Ukuphononongwa: "iMethionine". Imiyalelo yokusetyenziswa, ukubunjwa kunye nencazelo yokulungiselela

"I-Methionine" yisiza esinomphumo wokubulala i-hepatoprotective. Isilwanyana sine-amino acid, ubukho bokuba kubaluleke kakhulu kubantu. Le nkunkuma ayivelwanga ngumzimba kwaye ingena ngokutya. Xa umzimba ungenayo i-amino acid methionine, umyalelo, ukuphononongwa kukuthabatha ukuthatha isilwanyana "iMethionine", apho iqulethe khona.

Ukubunjwa kunye nefomu yokukhululwa

Isithako esisebenzayo i-L-methionine ibandakanyeka kwi-synthesis ye-choline, ekungabikho kwayo i-phospholipids kunye namafutha aqhutywe ngephene, kwaye ukuqokelela kwamafutha angathathi hlangothi kubonakala kwisibindi . Isilwanyana sifumaneka kwiifom ezintathu - iipilisi, isiraphu, iifomsile.

I-Pharmacological action

Isilwanyana sinciphisa impembelelo engafanelekanga yezinto ezinobungozi (umbane, i-immune, isetyhi, i-viral).

Icandelo elisebenzayo linceda umzimba uvelise i-amino acids e-sulfuri kunye nokukhuthaza imetabolism. I-methionine iyakwazi ukulawula imveliso ye-creatinine ne-epinephrin, yenza i-hormones, i-enzyme, iiprotini kunye namavithamini afana ne-ascorbic kunye ne-folic acid, kunye ne-vitamin B ₁₂ . Into esebenzayo nayo isebenzisekile ukuba ikhawuleze inkqubo yokususa i-lead, i-mercury kunye ne-cadmium evela emzimbeni.

Njengoko ukuhlolwa kubonisa, "i-Methionine" ithuthukisa amandla omzimba wokumelana nemiphumo emibi ye-radiation, uyayinceda xa wenza umthambo omkhulu. Icandelo leqela elisebenzayo liboniswa kwiikhonkwane, iinwele kunye nekhumba. Ngokwimeko yabo, kunokwenzeka ukuba bagweba ukuba i-amino acid ine-methionine eyaneleyo, equle isulfure, iyimfuneko yokwenyama kwesikhumba, ukukhula kwezikhonkwane ezinamandla kunye nobuhle beenwele.

Ukusetyenziswa kweziyobisi ngezigulane ezine-atherosclerosis kubangela ukunciphisa inani le-cholesterol kunye nomxholo okwandisiweyo we-phospholipids.

Amino acid isekela ubomi obuqhelekileyo bomntu. "I-Methionine" yokujonga ukulahlekelwa kwesisindo ichaza njengendlela yokuphatha kakuhle umsebenzi wayo. Isithako esisebenzayo sisomeleza isimiso somzimba sokuzivikela, sikhuthaza ukutya okuncinci kokutya.

I-Amino acid, ekhoyo ekubunjweni kweziyobisi, ayikwazi ukutshintshwa. Ngaphandle kwayo, ukukhula okuqhelekileyo nokulondolozwa kwe-nitrogen equilibri akunakwenzeka. Ngenxa yobukho balo emzimbeni, amafutha athile angathathi hlangothi.

Iinkcazo

I-"Methionine" imiyalelo yokusetyenziswa, ukuphononongwa kukuthabatha ukuthatha xa kukho iinkqubo zengqondo kwi-isibindi ezenzeka ngokungena kwamathambo e-hepatocytes. Isilwayo siboniswe kunyango kwiimeko ezilandelayo:

• Izilonda ze-Dystrophic zesibindi;
• Utyhefu lomzimba ngeesxibisi;
• I-hepatitis ye- etiology enobuthi ;
• Hepatosis;
• Cirrhosis.

Ngenjongo yokukhusela, isilwanyana "iMethionine" sinqunywe umonakalo wesibindi onobungozi obunxulumene nokungena kwe-chloroform, i-arsenic, i-benzene kunye notywala emzimbeni.

Kunokwenzeka ukuphumeza unyango oluyinkimbinkimbi kunye nokusetyenziswa kwesi siza. Ukunyanga kwabo, ngokusekelwe kwindlela edibeneyo, iqhutywe nesifo sikashukela kunye ne-atherosclerosis. Kufuneka kumgangatho ophantsi weprotheni, ukukhula okunyuka kwabantwana.

Njengoko ubungqina bubungqina, "i-Methionine" imiselwe abafazi abakhulelweyo abane-toxicosis. Kwiimeko ezinjalo, isilwanyana sifakwe kwiluhlu lweziyobisi ezifunekayo ukuze unyango olunzima. Indlela efanayo isetyenziselwa iingxaki nge-placenta kunye nokuntuleka kweprotheni.

Isilwanyana siyathandwa phakathi kwabakhi bomzimba. Kwiimeko eziphezulu zomzimba, i-Methionine ithathwa ngokukhawuleza isuse i-ammonia emzimbeni. Kuyaziwa ukuba xa iprotheni iphuka, i-ammonia yenziwa, ngoko abadlali bawusiza umzimba wabo ukuba ususe le nto ngokukhawuleza.

Ukusetyenziswa kwe "Methionine"

Ngokweenkcukacha ezichazwe kwimiqulu, abantu abadala banconywa ukuba bathathe i-500-1500 mg yesilwanyana. Kubantwana, i-dosage imiselwe ngumdala. Abantwana abancinci (ngaphantsi kweminyaka elilodwa) banqunywe i-100 mg yeziyobisi. Labo abaneminyaka engama-1-2 ubudala banqunywe u-200 mg weziyobisi, iminyaka eyi-3-4-250 mg. Iminyaka emi-5-6 iminyaka ikuvumela ukuba usebenzise u-300 mg weyeza. Emva kweminyaka eyisixhenxe, i-500 mg yesilwanyana ivumelekile. Ezi zizodwa ziza kuthathwa amaxesha ama-3-4 ngamaxesha angama-24 iiyure ezingama-24.

Ukuqwalasela ngolwazi ukuba imiyalelo neengqinisiso ziqulethe, "iMethionine" udakiwe ngaphambi kokutya. Kubalulekile ukuba ikhefu phakathi kokuthatha izilwanyana kunye nokutya livela kwiimitha ezingama-30 ukuya kwiyure. Ngokuqhelekileyo, oogqirha banika unyango ngolu hlobo lweentsuku ezili-10 ukuya ku-30. Kuyakwazi ukusebenzisa enye ikimu equka ukusetyenziswa kweziyobisi iintsuku ezilishumi kunye nekhefu ngexesha elifanayo nokuphindaphinda kwekhosi.

Ubude bonyango "I-Methionine", kwakunye neelayi, xa kubeletha umntwana kuxhomekeke kwimibandela emininzi kwaye kusekwa ngumbono ngamnye. Ngaphandle kokuqwalasela ubunjalo besithako esisebenzayo, ukungabi nengozi emzimbeni nasesikweni esiqhelekileyo sokukhulelwa, kwiimeko ezinqabileyo, isenzo se-L-methionine senza utshintsho oluthe xaxa - ukwanda kwe-coagulability, okubangela ukuba kubekho ukwenziwa kwe-thrombi, okubangelwa ukulahlekelwa ngumntwana. Umthamo wezokwelapha kumfazi okhulelwe unokunyulwa kuphela ngugqirha owamphatha.

Ukungqinelana

Kunconywe ukufundela ngaphambi kokuthatha imiyalelo yeyeza "iMethionine" yokusetyenziswa, intengo, ukuphononongwa. Kuyafaneleka ukuhlawula ingqalelo kwiimeko apho kungavunyelwe ukusela imveliso yonyango. Ukusuka kwiingqinisiso, imiyalelo ebalulekileyo:

• Ukwandisa ububele kumacandelo eziyobisi;
• Enpphapathy hepatic;
• I-hepatitis yemvelaphi yentsholongwane;
• Ukungaphumeleli kwe-Renal yesimo esibi.

Xa ukungafihli komzimba kuvunyelwe ukuba uphathwe kunye neziyobisi, ngaphandle koko kuphela ifom yayo enzima. Kubalulekile ukuphatha ezi gulane ngokuqaphela okukhulu, kuba kukho umngcipheko wokunyusa izinga le- nitrogen eseleyo egazini.

"I-Methionine" isetyenziswa rhoqo ngendlela edibanisayo, idibanisa namanye ama-amino acids efunekayo emzimbeni. Le ndlela ifunekayo ukuze kupheliswe ukungalingani kwama-amino acid. Ukuxhatshazwa kwemali kungabangela umonakalo kwiiseli, apho isibindi kunye nezinye izitho zenziwa.

Iziganeko ezimbi

Xa uthabatha iMethionine, imiyalelo yokusetyenziswa, intengo, ubungqina, iimpawu ezifana nokubaluleka kokufunda okungalunganga komzimba. Ngokwenene, isilwanyana sinyamezeleke. Impendulo engathandeki kakhulu. Phakathi kwezibonakaliso ezingenakwenzeka ezi zinto zihamba kunye neengcamango ezilandelwayo ngokuhlanza. Oku kubangelwa yimimiselo ethile yeziyobisi (ukunambitha, ukuvumba). Ukuba isigulane sinempendulo enjalo emzimbeni, ugqirha unokuncoma ukutshintsha iipilisi kunye nesiraphu ngeefomsile.

Kwimeko yokudlula ngaphezulu, njengoko ukuhlolwa kunye nemiyalelo ibonisa, uxinzelelo lwegazi luya kutshintsha, ukuphazamiseka kwe-tachycardia kuvela. Kwiimeko zamanqanaba angaphezu kweemfuneko, unyango olubonakaliswayo luboniswa.

Umzimba wezinye izigulane unokuphendula xa uthatha iilisi ngeempendulo.

Imiyalelo ekhethekileyo

Utshintsho

Abasetyhini abanomntwana, ukuphelisa ukubonakaliswa okungahambi kakuhle kwe-toxicosis, le nkunkuma inqunywe njengenxalenye yonyango oluyinkimbinkimbi. Njengoko ukuhlolwa kubonisa, "iMethionine" idibene ne-folic acid ne-vitamin B ₁₂ . Kubalulekile ukunamathela kumyinge ngamnye umiselwe ngumcebisi. "I-Methionine", ethathwa ngamanyathelo angaphezulu, ingaba yinto ebangela ukwanda kwegazi.

Izixhobo zoMsebenzi

Ngethuba lexesha lonyango, kubaluleke kakhulu ukugcina umlinganiselo we-amino acids, ngoko ke umlinganiselo wabo kufuneka ulinganise. Ukungabikho kokulinganisela kunye nobukho be-amino acid methionine xa kuthelekiswa nomgangatho wezinye i-amino acid kunokudala umonakalo kwisakhiwo seeseli zamalungu.

Ixabiso, ezifanayo

Ngaphambi kokuba unyango kunye neyeza "I-Methionine" xabiso, ukuhlaziywa rhoqo kuhlolisiswa zizigulane. Uhlobo oluqhelekileyo lweziyobisi (iipilisi ezinomxholo we-250 mg wezinto ezisebenzayo, ama-50 ama-pcs.) Unokuthengwa malunga nama-ruble angama-99-137.

Ukuba ufuna ukufaka endaweni yeso sigqirha, ugqirha unokuncoma "Acimethion" okanye "Banthionin". Umphumo omhle unikezwa ngeendlela ezifana ne "Meonin", "Atinon". Isenzo esifanayo sine "Amethionol". Ukutshintshwa kweziyobisi kungenziwa ngokutshintshwa kwamukelwa "Thiomedon".

Uphononongo

"I-Methionine" ayifaneleki kubo bonke abafazi abakhulelweyo, ngoko akuyona into ekhethwa kakhulu. Kuphononongo akukho khankanywe ngokuphuhliswa kwemiphumo emibi, ngokuqhelekileyo unyango luqhelekileyo.

Ukushiya impendulo yabo kunye nabasebenzi bomzimba. Ngokombono wabo, ngenxa yokuthatha iyeza ngezifundo ezimbini zeeveki, i-ammonia iyona nto iboniswe ngokusemandleni. Abadlali beekhosi baqalisa ukusebenza emva kweenyanga ezimbalwa.

Njengoko kwaziwa, "iMethionine" isetyenziselwa ukulahleka kwesisindo. Ukuphonononga kwalabo abalahlekelwa isisindo abahlali behle, ngenxa yokusetyenziswa okungalawulwayo kweziyobisi. Umthamo weziyobisi kufuneka uhlale ukhethwa ngugqirha, ngoko iipounds ezongezelelweyo ziya kuhamba, kwaye umzimba awuyi kuphazamiseka. Isiphumo esona siphumelele sinokufumaneka ngesondlo esifanelekileyo kunye nokunyuka komzimba.

Njalo udibanise ugqirha, ekubeni kwanokuba isicatshulwa esingenakubungozi singakhokelela kwiingxaki zempilo ezinzulu. Ukusetyenziswa kwe- "Methionine" kufuneka kwenziwe phantsi kolawulo lugqirha kwaye ngokukhawuleza kumlinganiselo othile.