Syndrome Cushing xa izinja: Iimpawu kunye nonyango loko. syndrome Cushing xa izinja: indlela yokuphila?

inkqubo yonyango - le yenye eemfihlelo enkulu emzimbeni wethu. Kwi kwamadlala ezidalwe libotshelelwe phantse zonke iinkqubo kwemichiza emzimbeni, kwaye utshintsho incinane hormone badla nemiphumela emibi vuhlayiseki. Ukuba sithethe ngayo entsimini amayeza lwezilwanyana, i eso sifo kakhulu eqhelekileyo, Cushing engqondweni. Xa izinja, amaxesha amaninzi oko kukwaphula kwenzeka kubantu abadala, yaye namhlanje sihlalutya ngokweenkcukacha ntoni na nendlela ukulwa nayo. Eli nqaku ulwazi kuphela, kuyo nayiphi na imeko, ukuba afunyaniswe isifo kwaye afumane unyango iirejimeni oyikhethayo kufuneka ubone ugqirha.

Yintoni syndrome Cushing kaThixo ezinjeni

Le ngezifo, esifunyaniswe eqhelekileyo ukuze ukuze ezinqwenelwayo. Ukuhlukunyezwa kukuba yebhinqa isilwanyana uqalisa izixa eliphezulu kakhulu anikezele cortisol. Le hormone ebaluleke kakhulu, nto leyo iyeza yendalo enamandla ukulwa ntshikilelo. Asiyi kuhlala phezu indlela amanyathelo kwale hormone emzimbeni, sinokuthi kuphela ukuba le nto iza kuqokelela zonke oovimba ukuze simelane iimpembelelo ezimbi yokusingqongileyo.

Njengokuba, iinzuzo eziqinileyo, kutheni echaza le nqubo, uthetha syndrome Cushing xa izinja? Isibakala sokuba ezo izixa hormone, leyo aqalile ume ngaphandle egazini, ifaka nokuba indlovu. A ingqondo yebhinqa, nto leyo ukulawula isixa hormone ngokubanzi ngaphandle kule nkqubo. Ngenxa yoku, lesilwanyana sakho ujamelene nemiphumo ebuhlungu kakhulu.

imiphumela emibi

syndrome Cushing xa izinja kukhokelela ekubeni ukuziphatha isilwanyana liyabutshintsha. Luvakaliswe ukuphazamiseka kwengqondo. Inja bathuthunjiswe rhoqo a, ukoma yindinisa. Oku kubangela umthwalo omkhulu kwi nezintso, yaye ukongezelela, kukhokelela ukuchama ngokugqithiseleyo. Le disorder zingaba yingozi kakhulu, yaye ngokukhawuleza ngokwaneleyo. Isizathu sokuba oku lula zichazwe ngokwemigaqo zomzimba. Le ephilayo uyakwazi ukudibanisa, yaye ngaloo ndlela kunxitywe izihlandlo eziliqela ngokukhawuleza. Xa kusenziwa lwezilwanyana kukho iimeko apho urhulumente inja seminyaka emithathu-lomzimba, abagulayo nesi sifo, kukwehla umzimba efanayo in inja iminyaka 13-15.

The main Iimpawu

Masibhale Ngoku sithethe ngendlela urhanela Cushing engqondweni ezinjeni. Okokuqala bonke abanini ahlawule ingqalelo kwanda. Esi silwanyana iqala ukubeka ngokukhawuleza ubunzima. Ngaxeshanye, ungabona unxano kakhulu kwaye rhoqo ukuchama. Le isilwanyana asikwazi elide ukunyamezela, yaye, nangona bande Inani leehambo, nangoku pissing ekhaya.

Eneneni, esi sifo asivelanga ndawo, yaye ngokuthe ngcembe ukuphuhlisa ezi mpawu mkhulu. Inja iba buthathaka kwaye ecubhukile, ozele, kodwa kubonisa ukutya kakhulu. SAGs isisu ngenxa izihlunu buthathaka esiswini. Kukho fatigue rapid kakhulu. Ngokuthe ngcembe ukwengeza inkqayi. iindawo ezinkulu esikhumba engenazinwele ngokupheleleyo. Amaninzi amaziko emzimbeni, kodwa hayi kwi entloko okanye iinyawo. Ukurhawuzelelwa engekhoyo. Ukuba lunganyangwa, kungekudala kakhulu kwisiqalo kwesi sifo ukuphuhlisa seswekile.

Ezibangela isifo

Enyanisweni, oogqirha bezilwanyana kufuneka iithiyori ezininzi kutheni izinja ubunzima kwesi sifo hormone. Noko ke, esona sizathu kuthiwa ithumba, ugwayimbo adrenal. Amaninzi, oogqirha bazama ukulungisa le meko ngoncedo kotyando okanye amayeza, nayo leyo neziphumo zazo icala lakhe. Nangona kunjalo, oku akusosizathu kuphela ezinokubangela syndrome Cushing xa ezinjeni. Ifoto ibonisa ukuba iinguqu zangaphandle ezithi zenzeke ngayo izilwanyana ezigulayo, kodwa kamva iya kubuyela mpawu thina.

Esinye isizathu isenokuba adenoma yebhinqa. Ngoko ke, kufuneka ukuba ahlole aze yebhinqa, kunye namadlala adrenal. Noko ke, ukufumana nethumba, ugqirha nje ukuqala umsebenzi wayo. Kufuneka isamele imise izibhaxu ingozi okanye yingozi, sisebenzisana, uze emva koko ukuqikelela ekuhambeni unyango.

sifuze

Kukho iintlobo ezithile, esi sifo iphakathi apho ixhaphake kakhulu ngaphezu kwabanye. Ngoko ke, olusemngciphekweni terriers kunye manqindi zonke iintlobo. Oku kuquka dachshunds, beagles, poodles kunye lutshintsho. Kaninzi sisifo abadala sifo abaye uwagqibile amashumi 7-10. Kule minyaka, oogqirha ukugcina kuphela isimo umzimba kangangoko kunokwenzeka. Noko ke, naye unesifo Cushing engqondweni, yaye eyingwevu ngokwanelisayo abatsha - ezinjeni ngaphantsi kweminyaka emibini. Esi sifo kuyingozi kakhulu kuba wenza ngoko nangoko kuzo zonke amalungu kunye neenkqubo, yaye ke ngoko, ngaphandle unyango olufanelekileyo, amathuba aphezulu nokufa kwesilwanyana, kwakunye ukuhla kakhulu kweminyaka yokuphila kunye nonyango eyaneleyo.

survey

Kubaluleke kakhulu ukuqinisekisa ethembekileyo syndrome Cushing xa ezinjeni. Lokufunyaniswa kwesifo inzima kakhulu, hayi zonke iikliniki banakho ukubonelela iimeko eziyimfuneko ukuze oku. Ubukhulu becala ugqirha kufuneka ahlole yezilwanyana ukuthabatha iimvavanyo eziyimfuneko. Yo fanekisela yi uhlalutyo lwezonyango kunye kwemichiza igazi nomchamo analysis, leyo kubalulekile ukujonga izinga protein.

Ukucacisa ugqirha umfanekiso unokuchaza-X-reyi, nto leyo ebonisa ukwanda esibindini okanye amatshe adrenal. Kuyimfuneko ukuphumeza ultrasound yadalwa ithumba kwamadlala adrenal. uphethwe olufanelekileyo akufuneki kuphela ukuqinisekisa syndrome Cushing xa ezinjeni. Iimpawu, unyango oluya kubanjelwa kwinqanaba elilandelayo ukuze ukwahlula yaye, ke ngoko, kubaluleke kakhulu ukufumana umthombo le ngxaki.

unyango

Le umzuzu enzima kunye noxanduva. Kweli nqanaba, ugqirha kufuneka ukhethe uthomalaliso kakhulu efanelekileyo. Ukubuyisela amanqanaba cortisol, ukuxhasa umsebenzi onke amalungu kunye neenkqubo - ngumsebenzi ophambili mlonyeni kuye ukususela kwafunyaniswa Cushing engqondweni. Xa izinja, unyango vandlakanyo lunokwenziwa ngeendlela ezimbini.

Indlela yokuqala - uqhaqho. Ubonisa ukuba zonke izilwanyana, kodwa kuphela abo ithumba kwamadlala adrenal. Kwimeko yebhinqa adenoma ngayo kusenzima, kwaye adrenal nje kususwe kunye nobomi bezilwanyana emiselweyo unyango hormone.

Indlela yesibini - zonyango. Kulo mzekelo, kwanonyango hormone, ukubuyisela amanqanaba cortisol. Le mveliso "Mitotane". Ukwamkela siqale umthamo 50 mg ngosuku ngalunye 1 kg ubunzima. Le idosi yemihla ngemihla yahlulwe 2-3 nasebusuku. Unyango kuyaqhutywa iiveki ezimbini. Imeko isilwanyana esweni kunye iimvavanyo zegazi. Ngokunciphisa amanqanaba cortisol egazini ukuya amaxabiso yokwakha kufuneka uye idosi drug-50 mg / kg kanye ngeveki.

Le khetho yesibini, elithanda emiselwe ngugqirha - ichiza "Ketoconazole". Okokuqala azimiselweyo abo izilwanyana abaye Cushing engqondweni kwisiqalo isakhula kunye nomonakalo isikhumba ezinzwaneni. Ukuthatha ichiza kwiveki yokuqala - 10 mg nganye 1 kg ubunzima bomzimba (ngaphezu ezimbini amanyathelo). Kwiveki yesibini idosi inyuswe ku-20 mg 1 kg ubunzima ngamnye (njengoko ngenxa amanyathelo amabini). Ekugqibeleni, kwiveki yesithathu unyango lubandakanya idosi yemihla ngemihla of mg 30 1 kg ubunzima nganye.

Indlela ukujonga ukusebenza konyango

Benchmarks yokuqala iya kuba iimvavanyo zegazi, ultrasound ze-x-reyi. Nangona kunjalo, kukho neziphawuli ezinokuthi mabavavanywe kwaye umnini. Oku ikakhulu ukuhla zokusela inja kwamanzi. Nangona kunjalo, khumbula ukuba imvelaphi iingxaki nga ukuphuhlisa kwanonyango kwizilwanyana. Le ukugabha kunye nokwanda ubuthathaka, silale kunye nokwala ukuba adle. iimpawu ezinjalo kubonisa iingxaki ezinxulumene kunye nezifo. Ngoko ke, ekuhlambululeni womzobo kufuneka nemvavanyo zaselaborathri yenziwe.

iziphumo zonyango

Sinokuba nethemba, ukuba unesifo syndrome Cushing xa izinja? Bangaphi bahlala izigulane ezinjalo? Le mibuzo badla kakhulu wacela ngabanini ukuba bezilwanyana. Ndimele ndithi ukuba isifo esinokunyangwa ichazwe inxalenye kuphela. Amaninzi, iminyaka yobomi, kwanasemva unyango ngempumelelo ayidluli iminyaka 2-3. C Oku kungenxa yokuba Cushing kaThixo syndrome - sisifo zeenkqubo ichaphazela zonke amalungu kunye neenkqubo, Ngumphakamisi inani lotshintsho vuhlayiseki. Le musculoskeletal, iinkqubo sentliziyo kunye ethukile. Okuhamba sifo kunciphisa ukuxhathisa umzimba ukuba ungenwe lula zizifo ezahlukahlukeneyo, kwakunye ukuba bandiqumbise ukunyuka okubonakalayo uxinzelelo lwegazi.