Medicine "primidone": imiyalelo esetyenziswa kunye nengxelo

Iinkampani Modern zoxubo mayeza ukuvelisa inani elikhulu zamachiza antiepileptic. Indlela ukuqonda ezahlukeneyo iziyobisi? Ukuze wenze oku, vula ku iingcali ezinamava. Yena uya kukwazi ukukhetha na iyeza kakhulu, nto leyo eya kuba negalelo isipho ebonakalayo malunga nesigulane eso.

Ichiza antiepileptic ithandwa phakathi izigulane kunye amagqirha na amayeza "primidone". Imiyalelo yokusebenzisa iziyobisi bathi, ifomu ukukhululwa kunye neempawu zayo ziya kwenziwa kancinane emva koko.

Ekwakhiweni, imilo kunye nokupakishwa

Thenga amayeza "primidone" banokuba ngeendlela ezimbini ezahlukeneyo. Ifumaneka njengokuba powder lupakishwa kwingxowa yeplastiki ezimbini-ezikroziswayo ibhokisi yekhadibhodi, ngokulandelelana. Oku kuthetha ukuba unako ukuthenga ngokohlobo amacwecwe imiqulwana blister kunye iibhokisana.

Le nto esisebenzayo kweli chiza enza primidone. Kwakhona iquka nezincedisi (kuxhomekeke iifom ukukhululwa).

Isenzo beziyobisi

Yintoni eyanceda "primidone"? Imiyalelo yokusebenzisa zibonisa ukuba eli chiza antiepileptic. Oku kunegalelo isiphumo onomoya thile, kodwa kunciphisa excitability ye-luvo ukuba ibekwe focus sokuwa.

Ziziphi ezinye iipropati ezendeleyo medicament "primidone"? lafa Kubalulekile xa ephelisa xi igazi 12 .mu.g / ml.

iipropati kinetic

"Primidone" (macwecwe kunye nomgubo) Drug ngokufanelekileyo ngokukhawuleza kwaye phantse ngokupheleleyo etsalwe iphecana zesisu. Ukufumaneka eliphezulu ichiza afunyenwe emva kweeyure ezintathu. Le bioavailability yale ichiza 90-100%. Egazini, Sithe nca kwiiproteni kancinci (malunga nama-20%).

Half-impilo yale arhente ziiyure 7-15.

Xa kwesibindi, lo medicament nenxalenye kuguquka phenobarbital (malunga nama-20%), kunye feniletilmalonamid. Ezi metabolites ilifa umsebenzi antiepileptic. Bona kwazona yi nezintso.

igazi yesigulane kuyimfuneko ukugcina yoxinaniso iziyobisi konwaywa 12 ug / ml. Kuyinto kwezi zalathisi igalelo cishe linyuke. Xa ezinye iintlobo sokuwa (umz, iintlobo ezingezo-convulsive of uxhuzula polymorphous kunye nezinye), isiphumo uthomalaliso akusoloko yimpumelelo. Kulo mzekelo, unyango ezintsonkothileyo.

Iimpawu zibonisa ukuba ukusetyenziswa kweziyobisi

Kwezinye iimeko, isigulane emiselweyo amayeza afana 'primidone'? Ukuphonononga baxele ukuba esi sixhobo ngendlela eyiyo ubaphatha sokuwa of imvelaphi ezahlukeneyo, kwakunye uxhuzula buso kunye ngokubanzi. Ngophuhliso ukuxhuzula focal, myoclonic kunye akinetic le amayeza kakuhle kangako.

Izimo ukuba amayeza

Kwezinye iimeko, musa ukumisela amayeza "primidone"? Imiyalelo yokusebenzisa kweengxelo ukuba Akuvunyelwe ukusebenzisa iindlela phambi kokuba hypersensitivity (kubandakanywa barbiturates), kwakunye kwegazi, isibindi kunye ukusilela kwezintso, ukukhulelwa, imitha kunye nokuncancisa.

Medicine "primidone": imiyalelo yokusebenzisa

Ziziphi oyidlayo kumiselwe ichiza ngayo ngoku? is he taken ngomlomo emva ukusetyenziswa isidlo kwindawo enye ngexesha elinye-ithamo mg 125. Emva koko, emva kweentsuku ezintathu, uthe inani iziyobisi kunyuke nge-250 mg kwizigulana abadala kunye 125 mg abantwana abaye ufikelele kwiminyaka yobudala-9.

Le uthomalaliso yaqhubeka de kwisiphumo oyifunayo.

Le idosi iphezulu yemihla ngemihla abantwana yi-1 g (ngokwezigaba ezibini) kunye nabantu abadala - 1.5 g

imiphumela emibi

Ngelishwa, phambi kwethu iziyobisi antiepileptic kaninzi ibanga iziphumo ezingafunekiyo. Ezi ziquka ukozela ngokugqithiseleyo, intloko ebuhlungu, isiyezi, ixhala, silale, isicaphucaphu, ianemia, ukugabha, leukopenia, negazi, kunye lymphocytosis.

kunqabile kakhulu medicament esebenzayo kunokubangela nystagmus, Ataxia, "lupus" syndrome, reactions ngengqondo, arthralgia, igazi megaloblastic, kunye nokusetyenziswa elide - ukuxhomekeka iziyobisi.

amacala libanda

Ukuthatha amathamo ezinkulu ichiza kunokubangela iimpawu ezifana nesiyezi, Ataxia, isicaphucaphu, nokudandatheka yomsebenzi central system luvo. Kuba unyango kweemeko ezinjalo isigulane ahlambe isisu, amalahle iyasebenza yaye nonyango nomqondiso.

Ukuhambelana namanye amachiza

Ukulungiselela "primidone" ithe potentiates ifuthe cyclophosphamide, methotrexate kunye sulfonylureas kwakunye hypnotics. Kwakhona ibalekisa ukutya, kwandisa umsebenzi microsomal enzyme zesibindi, kunciphisa ifuthe corticosteroids, acetaminophen, ISS, lakhula tricyclic, anticoagulants, "Chloramphenicol", "DTIC", "Cyclosporin" glycosides kwentliziyo "disopyramide", "Levothyroxine", "Doxycycline "" theophylline "," metronidazole "," Quinidine "," mexiletine "of ivithamin D,« fenoprofen, "caffeine" Aminophylline "yaye" oxtriphylline. "

medicament kujongwa kuyandisa CNS ukudakumba ezidityaniswe indlela isenzo depremiruyuschim engundoqo kunye notywala.

Drug "amphetamine" imenza ukufunxeka phenobarbital.

Kudibaniso గుర్తులు ibhaloni anhydrase inhibitors ziyanyuswa osteopenia.

Oku kunciphisa ukufunxeka arhente griseofulvin ukuba kunciphisa umsebenzi wayo nokubola. Kananjalo iphucula iziphumo abanetyhefu "enflurane", "methoxyflurane" yaye "halothane".

"Methylphenidate" ikhuthaza inhibition emzimbeni kunye primidone kwandisa eyavela egazini.

"Leucovorin" ngeedosi ezinkulu kunciphisa ifuthe primidone anticonvulsant. Kukwasebenza kwanjalo kuyo ichiza "phenylbutazone".

izincomo ezithile

Drug "primidone" ungasetyenziswa kunyango entsonkothileyo anticonvulsant. Ukurhoxiswa nokutshintshwa ichiza kwaba ngokuthe ngcembe.

Ngokucophelela, wamiselwa abantu abadala kunye immunocompromised. Ngophuhliso megaloblastic anemia medicament rhoxisa kwaye ukumisela unyango kunye vitamin B12 okanye folic acid.

Iarhente yesifundo kunciphisa reactions lengqondo abantu. Ngoko ke, oko akuthethi ukumisela abaqhubi bezithuthi kunye nabantu omsebenzi wakhe okuhlanganiswe ngoomatshini yingozi.

Ngokukhathalela eli chiza lisetyenziswa ebantwaneni.

ngendlela efanayo

Ichiza na indawo "primidone"? Analogue esi sixhobo zingathengwa kuyo nayiphi na ekhemesti okanye umyalelo kwi World Wide Web.

Ngokutsho iingcali, kufuneka iimpawu ezifanayo amayeza afana "hexamidine", "Benzonal" yaye "Phenobarbital".

baqinisekiswa

Abathengi abasebenzisa iziyobisi antiepileptic ezifana "primidone" abamshiyayo feedback kuphela HIV. Ngokutsho iingxelo zabo, ichiza alwa kakuhle umsebenzi walo. Oku kuthintela elivela kuzo ukuxhuzula oluphakathi kunye ngokubanzi. Kwakhona, eli yeza inceda ukwehlisa iimpawu ukuxhuzula.

Njengoko ngokuba ncomo ezimbi, phantse bonke ezichaza ukuba esi sixhobo inegalelo ukuvela kukho inani elikhulu yeziphumo ebezingalindelekanga. Ngoko ke, ukuba isicelo yeza onjalo kufuneka ibe kuphela ukuqeshwa ngugqirha.