"Isotretinoin": imiyalelo ukusetyenziswa, izalathisi, ncomo

Unyango lwezifo ulusu yenziwa ngenxa nemixube eziqulathe kwi isotretinoin yayo kuqamba. Le into ithathwa ngokuba umbulelo dermatoprotektivnym kwiipropati yalo ekhethekileyo. Ukulungiselelwa igama elifanayo isetyenziselwa ekunyangeni seborrhoea, induna. "Isotretinoin" imiyalelo yosetyenziso Kucetyiswa ukuba basebenzise kuphela emva kokudibana nogqirha wakho. Ngokutsho ncomo, i-arhente isebenza kwiinkqubo ukudumba apha esikhumbeni.

inkcazo

Drug "Isotretinoin" yeyona retinoid enamandla. Le yokugqibela ibhekisa yemvelaphi ivithamin A. Lenza into esebenzayo - isotretinoin - eyaziwa ngokuba retinoic acid kwaye ngokohlobo ngumgubo elityheli. Ubuncwane ekwaziyo lwaze iiseli umhlaza eyahlula ngokukhawuleza. Lo mhlaba lalibhekisela ukuba unyango lomhlaza.

Emva kwexesha elithile, abaphandi baye bafumanisa enye ipropati enyangayo into olungumgubo - iyakwazi ukunciphisa imveliso sebum ngokuthi ziyibuyisela ukukhula kakhulu yeseli epithelium imibhobho excretory. Lo mhlaba ikuvumela njengangoku lusetyenziselwa ukuba aphathe induna kakhulu lithetha "Isotretinoin".

Le imixube ezisekelwe kule esisebenza zingasetyenziswa zombini ngaphandle kwaye ngomlomo. iindlela Iqondo eliphezulu ukhetha wesikhumba emva kokuba kugqitywe uviwo malunga nesigulane eso.

wenza njani imithi?

Drug "Isotretinoin" umyalelo manual lithethelela ukuba usebenzise nokunyanga ngokuvakalayo Acne zixela indalo kunye nezinye izifo zolusu. Isiphumo therapeutic beziyobisi onesiphumo ngoko nangoko kuzo zonke izinto engabangela ezi zifo. Okokuqala, kunciphisa ukwenziwa sebum, pores zicocwa.

retinoid oluCwangcisiweyo kuthintela ukukhula ezincinane lwezidumbu acnes Propionibacterium, nto leyo ebangela amaqhakuva, namaqhakuva. Umfanekiso nangokurhala, kuqheleke pH - njengoko emagqabini yokulungiselela. "Izoteretinoin" lisetyenziswa ngokukhutheleyo dermatology kunye cosmetology. Icandelo Active ikuvumela ukuba singabi nefuthe kuphela iimpawu zesi sifo, kodwa ukuze kupheliswe izizathu ezabangela ukuba uphuhliso inkqubo arhabaxa.

Ubungqina obubonakalayo buxela ukuba ukusetyenziswa

Qaphela ukuba oku kucetyiswa ukuba usebenzise "Isotretinoin" ngaphandle kagqirha kagqirha. amalungiselelo Ixabiso ukuba isicelo bangaphandle ngokusekelwe ukwimo enye esebenzayo kuyahlukahlukana ngaphakathi 280-650 engange. Yabela iziyobisi azipilisi phambi ezimbi ezithile. Zezi:

• seborrhea;
• Rosacea (kubandakanywa esibi);
• Zonke iifom induna;
• induna nodulocystic;
• iintlobo ezahlukeneyo dermatitis;
• ichthyosis naso.

Uninzi lwezi zigulo unobangela obumanyeneyo imvelaphi - amadlala ngokugqithiseleyo sebaceous. Oku kukhokelela uphazamiseko esinzulu esikalini eqhelekileyo sangaphandle.

Yintoni umphumela indlela?

Ngokutsho izifundo ezininzi, ukusebenza beziyobisi baqiniswayo ezahlukahlukeneyo izifo zolusu. "Isotretinoin," kunciphisa kakhulu umsebenzi unamadlala sebaceous (90%) kwaye normalizes iinkqubo ibakho esikhumbeni. Oogqirha bacebisa ukusetyenziswa nkqu kakhulu lwe amayeza amaqhakuva azipilisi "Roaccutane". Isotretinoin lisetyenziswa into engundoqo esebenzayo.

Iindlela ukuba isicelo mlonyeni ezibubungqina kakuhle kunyango amaqhakuva, Rosacea, kunye dermatitis. Ezi retinoids zingasetyenziswa ndinomoya lokuphengulula izifo zolusu. Iingcali zithi ichiza ngale ndlela kuba ikhuseleke kakhulu umzimba ngaphezu njengezingxobo. Xa ngomlomo isotretinoin eyavela ngegazi luyanda ukuya 2,000 ng / ml. Ukuba usebenzisa amafutha, izinga akayi ngaphezu kwe-60 ng / ml.

Amalungiselelo esekelwe isotretinoin

Le esisebenza isotretinoin imiyalelo zokusetyenziswa ibhekisela yendalo retinoids. A Inani elincinane ezi zihlanganisi sebenzi kakuhle umzimba, kuba nempembelelo entle kakhulu eluswini, kunciphisa imveliso sebum, yiba inyathelo elwa. Amanye amalungiselelo yangaphandle iqulathe isotretinoin:

1. amafutha Retinoic.
2. "Izotreksin" (gel).
3. "Retasol" (solution).

Ukuze ulawulo yomlomo ezimbi kakhulu lweengcali yesikhumba amayeza emiselweyo ezifana "Aknekutan", "Roaccutane", "Cima". Ukwakhiwa (isotretinoin kusetyenziswa njengempembelelo esebenzayo), kwaye idosi ingahluka.

imiphumela emibi

Xa kunene oyidlayo isotretinoin ibanga iziphumo ebezingalindelekanga. Ukusuka a umgama kuvela kaninzi amajoni omzimba. Izigulane ezikhala irhashalala, ukuba bomvu, bechuba ulusu ezintendeni kunye kweentende zeenyawo, ukurhawuzelela, iipleyiti nail muscular. Kwakhona kuyenzeka ukuvela cheilitis - sifo echaphazela ulusu emilebeni.

Inkqubo luvo kukuba, ezinye izigulane nazo ukubandezeleka ngenxa ekunyangeni "Isotretinoin" iziyobisi. Ukuphonononga lubonisa ukuba kubonakale intloko, ukudinwa ngokugqithiseleyo, acuity ezibonwayo kakuhle, ukudandatheka asakhasayo kunye ngengqondo. Abantu abane sisifo sombefu kubantu kwimbali ukuba ichiza kuyingozi kakhulu. Oku kunokukhokelela bronchospasm. ziziphumo ebezingalindelekanga kwi amalungu yombono olwaboniswa iimpawu ezifana keratitis, blepharitis, neuritis optic, conjunctivitis, ukuluma kwamehlo.

Ngomhla inxalenye wokugaya iphuhlisa pancreatitis, urhudo, ukopha ngaphakathi, ukugabha, nangokurhala wamathumbu mucosal, ihepatitis. Arthritis, iintlungu amalungu izihlunu, hyperostosis - iimpawu imiphumela ebuhlungu isotretinoin kwinkqubo musculoskeletal.

Izimo

Okokuqala, le ncwadana "Isotretinoin" umyalelo iziyobisi lithintela ukusetyenziswa ngethuba lokukhulelwa okanye uyilo. Le nto ke embryotoxic kunye neziphumo yaManzi naMahlathi, nto leyo enokukhokelela ekubeni mgaqweni kuphuhliso nokuzalwa iziphene olungekazalwa. iingcali kwakhona ukuqala ukucwangcisa ukukhulelwa hayi ngaphambi ngaphezu kweenyanga 3-4 emva kokuphela amayeza unyango. Ngeli xesha, amanqanaba isotretinoin emzimbeni ukuba zibuyele esiqhelweni.

Akuvunyelwe ukuba ukuthatha naziphi na retinoids ngexesha zisanyisa, xa kwimeko hypersensitivity nobandlululo, kudityaniswe ntsholongwane tetracycline iziyobisi. Ulawulo ngomlomo amayeza contraindicated kwiimeko ukuphazamiseka kakhulu wesibindi, nezintso kwi nokwanda lipids kwi serum igazi ezinezigulo. Izigulana hypervitaminosis A kwakhona isotretinoin ayifanelekile.

Ixabiso le mveliso ifikelelekayo ezisekelwe le nto - 280-350 engange. Unyango irejimeni, umthamo, analogs ukhetha kuphela inyanga.

Indlela ukuthatha?

Isotretinoin yimilo iipilisi ze yolawulo ngomlomo kufuneka asele xa kutyiwa. Ithamo yokuqala ongowona ngaphantsi kwe 0.1 mg kwekilogram ubunzima bomzimba isiguli ngasinye. Kamva ithamo kufuneka kwandiswe (kwimeko ezithile malunga ezintle kunye nokungabikho neziphumo ebezingalindelekanga).

oyidlayo avareji ngemihla (0.5 g) ukuba kwahlulwa ngezigaba eziliqela. Kuxhomekeka ebukhulwini sigulo ukuze zinongezele. Khumbula ukuba mini ingathatha hayi ngaphezulu kwe-10 iigrem isotretinoin. unyango Drug idla ixesha elide, kwiiveki 16-24. Isithuba phakathi khosi unyango kufuneka ubuncinane iinyanga ezimbini.

Drug "Roaccutane"

Ixabiso medicament sezingeni eliphezulu kwaye zomyalelo 2700 engange ipasile (20 mg balawule). Umenzi yinkampani Swiss zamachiza, "Hoffman-La Roche." "Roaccutane" njengezingxobo olusebenzayo amaqhakuva nekrwada yilahleko, keratosis pilaris, ichthyosis, keratoderma.

Ubude unyango kuxhomekeke kuhlobo sifo, kwaye idla ngokuba ziiveki 2-4. Usuku kufuneka 0.5 mg ezimbaxa esebenzayo ngamnye 1 kg ubunzima nomonde. Ngokwesiqhelo ukunyamezelana "Roaccutane" Kufanele aqale Inqanaba lesibini unyango, okuhlala malunga 20 iiveki. Kulo mzekelo, ugqirha kufuneka esweni sifo okuhambisa. Ukuba kukho ukuhla izitshanguba nge 70-80%, ichiza sidla irhoxisiwe.

Iimpawu ze isicelo

Ngexesha unyango "Roaccutane" ukuqhubela phambili kwesifo kunokwenzeka. Kule meko kuyimfuneko ukunciphisa ukuba idosi zisezantsi (0.5 mg / kg). Ngokuqhelekileyo, okuhambisa entle ixesha elide japan unyango inokubonakalisa ngokusebenzisa iinyanga 1,5-2 emva kokuqala unyango. Nangona kunjalo, kwiimeko kakhulu ngayo ifuna ikhosi elide lolwamkelo esikolweni "Roaccutane" iziyobisi.

Ixabiso ichiza ngokusekelwe isotretinoin ixhomekeke umthamo isithako esebenzayo. Le njengezingxobo anokuqulatha 10 okanye 20 mg yale ezimbaxa. oyidlayo zezifundo kunye nonyango iirejimeni neziyobisi akufuneki kunokubangela iziphumo ezingalindelekanga. Iingcali Guest bathi "Roaccutane 'Wanyamezela kakuhle zizigulane.

Isisombululo "Retasol"

component sangoku arhente yi isotretinoin. Izimvo ezigulane kunye dermatologists nokuqinisekisa ukusebenza konwaywa ichiza. kuqulunqo into esebenzayo iqulethe 0,025 mg 1 ml. Isisombululo ngaphandle inyathelo anti-ezithintela ukosuleleka kunye lokuzivuselela, ibe nempembelelo entle isiqabu kwesikhumba. Amalungiselelo yenzelwe isicelo ulusu uzihlambululayo. Ngomhla we-nkqubo kufuneka liphindwe kabini. Ubude unyango "Retasolom" kuvame 4-12 iiveki.

Akukho mfuneko ukusebenzisa isisombululo zidityaniswe namanye retinoids. Oku ivule uphuhliso hypervitaminosis A. It alikwazi ukugunyazisa "Retasol" tetracyclines kwi unyango eyandileyo umngcipheko xi intracranial.

Xa uhlobo sisombululo zeziyobisi zingasetyenziswa unyango induna kule abafikisayo evela kweminyaka eli-11 ubudala. Iindlela Kwadlula ulingo lwezonyango, apho ukhuseleko yayo singqiniwe. "Retasol" ezilungele ulusu olunamafutha.

baqinisekiswa

Izigulane ezininzi ziye zasetyenziswa ukuze unyango yemveliso esekelwe into esebenzayo ezifana isotretinoin ngempumelelo. Analogue ala machiza kufuneka ukhethe yincutshe.

In kwiinyanga nje ezimbalwa unyango, i retinoid enamandla yendalo ikuvumela ukuba bahlukane amaqhakuva, induna Rosacea. Okunye isifo solusu kakhulu efuna izifundo ngokuphindaphindiweyo unyango. Kuphela kukwiimeko ezinqabileyo, kukho iziphumo ezingalindelekanga, kaninzi kubonwa yi amajoni omzimba: irhashalala komzimba, eyomileyo dermis ukuba bomvu. Akuvunyelwe ngokungqongqo ukuba uthathe iziyobisi ngokusekelwe isotretinoin ngexesha izicwangciso lokukhulelwa, ephethe usana okanye zisanyisa.