Inyumoniya Eosinophilic: inkcazo impawu, ebangela kunye neempawu zonyango

isifo semiphunga ezimandundu, ezifana pneumonia, azisoloko zibangelwa flora bacteria. Ukuphazamisa homeostasis eliphezulu kwaye asezantsi iphecana zokuphefumla ungakwazi irhorho, nomngundo, iziyobisi, immunodeficiency, negazi. Yaye kwiimeko ezinjalo, eosinophilic pneumonia kuphuhliswa.

definition

inyumoniya Eosinophilic - inkqubo zophendlo lwezifo emiphungeni, nto leyo luphawulwa ukuqokelelana ngokugqithisileyo eosinophils kwi alveoli. Kukho iindidi eziliqela okanye ezahlukeneyo kwesi sifo, nto leyo ukuphuhlisa nangaliphi na ubudala.

Ngokwezonyango, cishe yinto enzima ukugula ezibangelwa iintsholongwane, ngoko ke focus eyinhloko phezu nemvavanyo zaselaborathri diagnostic: ngokupheleleyo segazi, smear. Kwiimeko ezininzi, emva kujongwa uhlobo lwesifo baqalise unyango iihomoni steroid uthinte adrenal. Oku kunceda ukunciphisa indlela yokukrala kwaye yokungenelela indlela iimpawu yinyumoniya. I-ALS kwezi zigulane kukholekileyo ngokubanzi.

indaba

inyumoniya Chronic eosinophilic, oonobangela ngelo xesha ayaziwa, echazwe yokuqala kwinkulungwane ye-omabini, ngowe-1969, ugqirha Harrington. Wayengenguye oneentloni, ngoko ethile isifo igama layo, yaye emva kokupapashwa lesayensi baqala ukubiza i syndrome omtsha ngezifo Harrington.

Ngaphambi kokuba lolu nqaku eosinophilic inyumoniya kuye kwaziwa njenge sifo ukuvela emiphungeni emva kokuba bosulelwe izinambuzane okanye nokwamkelwa ongalawulekiyo iziyobisi. Kwiminyaka engamashumi amabini kamva, ngowe-1989, wabonwa amayeza, ibinzana elithi "pneumonia eosinophilic oyingozi".

umyalezo weimeyile

Ukuchonga izinto eziliqela, nto leyo phantsi kwempembelelo yinyumoniya eosinophilic luphuhla. Oonobangela, iimpawu zihlobene. Umzekelo, iintlobo nokoyika pneumonia okubangelwa icuba (zombini esebenzayo kunye passive), aleji iziyobisi ukunciphisa zokuzikhusela zomzimba ne-HIV okanye i-AIDS okanye. Ukuba akukho nalunye lwezi sezizathu ayifaneleki, kucingwa ukuba inyumoniya idiopathic.

inyumoniya Chronic eosinophilic zingenziwa ukumqumbisa yi ezinzwaneni (aspergillosis pnevmomikoz) ohlaselo helminthic (ascariasis, echinococcosis), ukusetyenziswa elide neziyobisi zisidimaze amajoni omzimba (steroids, cytostatics), izifo ezondeleyo samathambo nokuqina zomzimba (isifo samathambo, Kaposi kaThixo).

Eosinophils abe imisebenzi ibakhusela umzimba, kodwa njengoko komtshiso - le yinkqubo ekuqhelekileyo lwezidumbu, xa kukho ikhondo ngokugqithiseleyo ngokukhawuleza, wayengase nefuthe elibi kwimpilo yabantu.

Pathogenesis

into Etiologic ngeendlela ezininzi uchaza indlela yokuphuhlisa eosinophilic inyumoniya. Oonobangela, iimpawu, unyango - yonke into exhomekeke kule. Lembombo olu hlobo yinyumoniya yi nokwanda kwenani elikhulu eosinophils emzimbeni zemiphunga. izifo ezininzi, kubandakanywa nangokhwekhwe, isifuba, okubangelwa indlela ngogonyamelo kakhulu kumzimba ukukhulula umchiza.

Amayeza kunye nezinye izinto eziyityhefu liyitshintshe reactivity of eosinophils kwaye yenza ukuba usengozini. arhente Anti-ukudumba, imithi, iziyobisi kubangela uxabana ezikhokelela kuphuhliso yinyumoniya eziziisekondari. Ukongeza, izinto ezibangela ukuvela kukho inani elikhulu eosinophils kwi esiqwini, ibhekisela umsi wecuba okanye umphunga imichiza.

izifo olwaye lwamfimfitha

Oogqirha iindlela ezintathu yinyumoniya ngexesha parasitosis. Okokuqala - nokungazali ekumfimfitheni kwi kwemiphunga, owesibini - inxalenye umjikelo wobomi ziimpethu, kwaye elesithathu - yegazi zokuhlola Random. Ukuze kujongwane nazo umzimba ithumela eosinophils. Kufuneka bawaphikise-nuclear cytokines, prostaglandins, leukotrienes kunye nezinye izinto akhutheleyo lokuphelisa ziimpethu. Kodwa kunokuba kubangele inyumoniya.

Ngokukodwa kuqaliswa ancedisana ye tapeworm asezantsi iphecana yokuphefumla, Echinococcus kunye ezifana inyama yehagu tapeworm, kwakunye liphiko semiphunga. Ukuhlala emiphungeni kunye nokufikelela ioksijini esesibhakabhakeni olufunekayo ascarids, ugritsy isisu, hookworm kunye hookworm. pneumonia Eosinophilic, nto leyo ibangelwa Iintsholongwane ngasentla, nelaziwa ngokuba Loeffler engqondweni. Egazini emiphungeni ukufumana amaqanda Trichinella kunye schistosomes.

ikliniki

nzima Ngokuqhelekileyo, le therapist, pulmonologist, okanye izifo nokuba ezosulelayo xa uqala ukuphendula umbuzo wokuba yintoni eosinophilic inyumoniya nomonde. Iimpawu, nokuba kuthathelwa ingqalelo etiologies ezahlukeneyo ziyafana kakhulu omnye komnye. Isigulane ikhalazela of ukukhohlela, ifiva, ukuphelelwa umoya kwaye ukubila ebusuku. Emva ezimbalwa kwiiveki emva kokuqala ukukhohlela, ukuba kwenziwa nto, uya kuqaphela iimpawu insufficiency decompensated zemiphunga. Kwimeko enjalo isigulane kufuneka idluliselwe umoya ngumntu.

inyumoniya Chronic eosinophilic kancane kancane, kangangeenyanga. Izigulane ukunciphisa umzimba, zibe ukuphelelwa umoya, ukutswina kunye ekhohlela, ubushushu bomzimba lihla ngezantsi subfebrile. Ngamanye amaxesha iimpawu asekelwe sombefu, nto leyo eyenza uxilongo kunye ukhetho engalunganga zonyango.

ubunzima abaninzi ngenxa uxilongo yinyumoniya iziyobisi eosinophilic kudala. Iimpawu, unyango kunye nothintelo ukufana kwayo ezomeleleyo aspirin isifuba, ukuba ulahlekisa ugqirha. Xa izifo olwaye lwamfimfitha iye ngqo ixesha prodromal, leyo kusenokubonisa ukuba ihlaselwe helminthic.

ekuxilongweni

Ekubeni pneumonia ngokwezonyango eosinophilic phantse akukho kwahluka enye pneumonia, uxilongo isekelwe elebhu kunye nophando zomculo. Ngokubanzi, uhlalutyo eosinophilia igazi abuthethileyo phantsi nokuthelekelela fluoroscopic zotshintsho pulmonary okanye ngekhompyutha Itomography buqapheleke iimpawu zophendlo lwezifo. Ukuze uqinisekise uyakwazi biopsy lwe inwebu lung, ngokunjalo ukwenza egungxula kunye komhlaba bronchus ngexesha bronchoscopy.

Ukuchonga ubuhlobo amayeza, hlala iindawo iikhemikhali uyosuleleka, okanye umhlaza, kufuneka balujongisise ngenyameko imbali yezonyango yesigulane, kwakunye ukuqokelela imbali eneenkcukacha zobomi kunye nezifo. Ukuba, emva kokuba onke uphando, unobangela ayide nako ukuchonga, ngoko uxilongo irekhodwa yingqele idiopathic eosinophilic.

Qiniseka ukuba mephu ibonisa iqondo ukuphanza sokuphefumla. Ingaphelanga iveki ekuqaleni sifo kukho iimpawu zokuqala kwalo;
- izilonda ezininzi ijwabu lung;
- ukuqokelelana ulwelo em- pleural;
- leukocytosis kunye nezinga neentlenge erythrocyte ephakamileyo kuhlalutyo jikelele begazi;
- amazinga immunoglobulin E;
- spirometry yokuphefumla ibonisa ukuhla umthamo semiphunga.

unyango

Kwanangaphambi uxilongo lokugqibela ziza kubekwa - inyumoniya eosinophilic, unyango iqala yonyango umguli kwagqirha.

Ukuba pneumonia kuza emva, kuyimfuneko ukuba ukunyanga esi sifo engundoqo: ithumba okanye bohlaselo worm. Oku kuya kunceda ekunciphiseni iimpawu yemiphunga nezengekho bachache ngokukhawuleza.

Ukuba unobangela isibetho asiqhenqethanga ichongiwe, owabelwe unyango glucocorticosteroid. Bona isuswe kakuhle impendulo kwiintetho ezikralayo, lagxila iseli inwebu, ukunciphisa ubushushu. Uxolelo yimpumelelo ngokukhawuleza - ngosuku lwesithathu okanye lwesine. Kodwa le iyeza ayipheli apho. Zanyamalala kweempawu akuthethi ukuba isifo eso sinyangekile na. Ngoko ke, corticosteroids, isigulana kuthatha inyanga, kunye ukuncitshiswa chu idosi ukuya kwindawo apho iindlela negalelo diagnostic musa ukuqinisekisa isenzo.

Ifom ezingapheliyo isifo kufuna unyango iinyanga ezintathu okanye ngaphezulu, nasemva yokuduka iimpawu zonyango. Likakade ezi inyumoniya kunokwenzeka kwisiqalo zokurhoxa ngokukhawuleza of corticosteroids. Kwezinye iimeko, isigulane kufuneka batshintshele umoya ngomatshini.

Outlook

Ukuba inyumoniya eosinophilic sisifo yesibini nomhlaza okanye parasitosis, ngoko isiphumo ixhomekeke nokuqukuqela ngezifo ngxabano. Akubulali, kodwa unyango ezaneleyo ngexesha kwenzeke.

inyumoniya Chronic eosinophilic ithe gqolo ukuba ziphinde phezu kobuso glucocorticosteroids. Ngoko ke, ezinye izigulane ezithatha la machiza ubomi. Kodwa kule meko, kukho nobubi. iziphumo ebezingalindelekanga zonyango, ezifana prednisone, unga nciphisa kakhulu umgangatho wobomi babantu. Ezi ziquka: isilonda Peptic, kwamathambo, kushingoid, yehle nezifo.

lwezifo

Njengomgaqo, inyumoniya okubangelwa izinambuzane eziqhelekileyo ngakumbi kwimimandla ezisoloko zikho kule kwamagciwane. Lo isenokuba efudumeleyo, neSiberia, i lweMeditera okanye nayiphi na umlambo ethile.

Acute eosinophilic inyumoniya ingaqala nanini na ubudala, nkqu nabantwana abancinci kakhulu, kodwa ke inkoliso yabo ubunzima kubantu eliqina ukusuka kumashumi amabini ukuya kumashumi amane. Xa ukugula kukho abathile ucalucalulo ngokwesini - amadoda ukugula kakhulu ngaphezu abafazi, ngenxa yokuba esi sifo sibangelwa ugwayi. Kwiincwadi zonyango ngoku kukho iinkcazelo yinyumoniya eosinophilic emva konyango radiation umhlaza webele.

inyumoniya Eosinophilic ezinjeni

Izilwanyana ingafunyanwa nayo inyumoniya eosinophilic. Oonobangela, iimpawu, ukuthintelwa kwalo sifo ifana kakhulu ngabantu. Ngokufanayo, oonobangela esi sifo: irhorho emiphungeni, nomngundo, uxabana umungu, izinambuzane, iikhemikhali kunye namayeza.

Inja saphawula omzimba nkomoni ebangela kwemiphunga ijwabu idibane eosinophils. Ndandifeketha ukwahlukana asezantsi unciphisa, kukho iphuhlisa fungi yayintsholongwane eyosulela ezibangela inyumoniya. Esi silwanyana ubulawa yi asidi hypoxia. Le klinikhi iyafana ukhohlokhohlo yabantu, ukuphelelwa umoya, ubuthathaka, ifiva, ukungabi namdla wokutya, ukwehla kobunzima bomzimba.

Kuba isifo usebenzisa uvavanyo lwegazi,-X-reyi kwemiphunga, bronchoalveolar lavage cytology, zululwazi. Kwi X-ray ebonakalayo lung izihlunu nokudumba, ubukho weseli granuloma, nkovu esiludumbo mediastinal nokungabi hilar nokwandiswa umthunzi intliziyo. Emva Ukucacisa lo yinyumoniya umyalezo eosinophilic, ugqirha wezilwanyana unika unyango ethile ejoliswe bayeke isifo zaseprayimari. Kakhulu ngempumelelo - corticosteroids, kunye elwa bronchodilators. Ngokuqhelekileyo, izilwanyana ahlale unyango lobomi.