Igciwane lohlobo Epstein-Barr: ukufaneleka, esandulwa kumiliselwa, iimpawu ezivela eklinikhi, unyango

igciwane lohlobo Epstein-Barr intsholongwane (mononucleosis esosulelayo) - yayiyazi esosulelayo isifo wentsholongwane egazini. Luphawulwa fever, lymphadenopathy, nkovu ring oropharynx, Banti syndrome.

Ukuhambisana

Kufumaneke igciwane lohlobo kunye Epstein-Barr intsholongwane becala ebuntwaneni yaye sisalathisi intswelo omzimba lomzimba. Iarhente causative na intsholongwane herpes, nto leyo ingqalelo inyama lymphoid. Kulapha ukuba kukho enomfanekiso ntsholongwane. Kukholelwa ukuba le ntsholongwane ukuze negalelo umhlaza ngomlomo, lymphoma Burkitt kaThixo. esosulelayo mononucleosis syndrome kunokwenzeka kunye nezinye ii-arhente, nto leyo ingqalelo inyama lymphoid.

lwezifo

Usulelo lwenzeka sisigulane okanye umnini usuleleko yabantu ngexesha close contact. Abantwana sifo abaminyaka yobudala eyi-2-7 kwithuba ebusika-intwasahlobo.

Pathogenesis

igciwane lohlobo Epstein-Barr intsholongwane umkhathalele kwinkqubo emithanjeni. Ngoko ke waqalisa lo pathogen ngokufuthi nge ring pharyngeal lymphoid. Esi simo ngenxa kukuvela ukudumba kunye anozizi uxakaxa, ngeempumlo ukuphefumla nzima.

Kunye nokuqaliswa kwe loqhambuko lwe gciwane wonke umzimba ngalo igazi kunye nkovu. Ngelo xesha kuchaphazela iindawo nkovu, udakada, isibindi, lomongo wethambo, ukuphuhlisa izidubuli iinkqubo hyperplastic uvelichvayutsya kumaqumrhu umthamo.

Epstein-Barr intsholongwane losuleleko: Iimpawu

Emva kweentsuku 5-20 emva kokuba usulelo liphuma kabukhali ukuba ^C lobushushu 40 °, yempilo enkenenkene, kwaba nzima ngeempumlo ukuphefumla, kukho intlungu emqaleni. Intamo aluve likhubazeke ngenxa ezalathelwe banzi nkovu. Ngelo xesha ukwanda onke amacandelo neuropathy visceral. Tonsils kalanga, mbile, kunye patina emhlophe-emthubi okanye kumdaka-hina. Oku kukhokelela nobunzima uphefumlayo. Isikhumba ibonakala irhashalala zahlukahlukene kakhulu ngaphandle eyendawo ngqo. Hepatosplenomegaly - into rhoqo. Kubonakala isikhumba bulubhelu amancinci kunye sclera, iimpawu kwesibindi.

ekuxilongweni

Kuphando leukocytosis igazi ibhaqwe kwiiyunithi million 20-30, ukwandisa inani monocytes, ukwanda yibilirubin, ALT. Xa PCR DNA intsholongwane labonwa serum egazini kunye nokuzimisela yexabiso. Ngempumelelo eliphezulu usebenzisa haemagglutination, latex agglutination, ELISA, ukuba IgG kunye IgM.

Epstein-Barr intsholongwane losuleleko: unyango

Isicelo kwixesha nokoyika interferon, acyclovir, tsikloferona unika iziphumo azingqinelani. Xa uqhagamshela nezifo ubovu ezizisekondari neentlobo kakhulu zesi sifo kuyacetyiswa ukuba kusetyenziswe nemithi (acyclovir) kunye steroids: ngeedosi ngokulinganisela prednisolone. ampicillin Isicelo contraindicated kuba eyenza isenzeko ukusabela sokuhlasela.

Outlook

Kwi-USSR igciwane lohlobo kunye Epstein-Barr intsholongwane akaninikanga ukufa enye. Kukho iimeko kukufa ngenxa yeengxaki: komsipha splenic, kobuchopho, myocarditis. Kwiimeko ezinqabe kakhulu, kukho chronicity usulelo.