Ichiza "Novocaine": imiyalelo ukusetyenziswa, ixabiso. "Novocaine" ukukhulelwa

Medicine "Novocaine" yi iintlungu iziyobisi olusebenzayo. Amayeza kuluhlu lwe izixhobo zonyango ibalulekileyo.

iipropati amayeza "Novocaine" iziyobisi

Imiyalelo yokusebenzisa ibonisa ukuba chiza lokudoma umsebenzi eliphakathi wengingqi, sisetyenziswa ngokubanzi yezonyango. Ukulungiselela "Novocaine", nto leyo isiseko obuthathaka, imijelo sodium uthintelwe yi ziyibuyisela umva le uphuhliso andise neemvakalelo kuhlangana luvo kunye neziphelo. Xa efumene iziphumo medicament utshintsho nekhono kwizisele neuronal, kunye neziphumo ezibalulekileyo kwi kokuphumla amandla unganikezelwanga. Ichiza ofihla andise neemvakalelo intlungu.

Ngexesha sokufunxa kwaoko ubengena negazi xa ilawulwa yegazi kukho ukuhla excitability iinkqubo peripheral cholinergic, nokuncipha nokukotshwa kokukhutshwa acetylcholine neziphelo preganglionic. Le medicament "Novocaine" (umyalelo manual ucacisa ngale) ishenxisa ziba imisipha agudileyo, kunciphisa excitability kwendawo lwemoto ye uthinte kwengqondo iqhosha.

Ngokuba ukusetyenziswa efakwa, lo isinyibiliko antiarrhythmic, iqinile, antishock, isiphumo iintlungu, kwandisa ixesha elinjubaqa, ngokuphawulekayo kunciphisa conductivity, kunye ukuzenzekela excitability. Xa ukusetyenziswa ngeedosi eziphezulu Inokwenzeka yaphula Uhanjiso izihlunu luvo, unditsho zikhona.

Iyeza ususa aziqhekeza ifuthe phantsi isiqu ingqondo, nempembelelo ngxelo imbi kwi ingqondo polisinapticheskie. Kuye umsebenzi mfutshane kumzimba. Action nokungena zomzimba ithatha imizuzu engama-30 ukuya kwiyure 1. Isisombululo "Novocain" laqalisa izigulane intramuscularly abadala kumanqanaba okuqala ezimbi nga ngempumelelo ukulwa nezifo ezinxulumene ne ukusebenza kakuhle kwenkqubo luvo, inkantsi ebuchotsheni, nemithambo kunye hypertension nemithambo.

Ichiza ayiqondakali afunxwa yangaphakathi. Xa Inaliti-arhente esebenzayo ngokukhawuleza yangena egazini, uya hydrolyzed yi esterases ancedisana plasma, ukwakha metabolite emibini esebenzayo: PABA (bachasene iziyobisi sulfa chemotherapeutic) kunye diethylaminoethanol (ukuba ngcathu inyathelo vasodilating). Neboniswe izintso eluhlobo metabolites.

Ukubunjwa kunye nokumila "Novocaine" iziyobisi

kweziyobisi Iveliswe njengesisombululo ukuba isitofu ocacile ulwelo, enemibala, xa ampoules umthamo ukusuka ku-1 ukuya 20ml. Ipesenti esisebenza olunikezelweyo 0.25 no 0.5. Ukongeza, ngabo- ze-amabini ekhulwini ukukhululwa "Novocaine" solution ukulungiselela. Ixabiso le fomu 15 engange.

Popular kunye nomgubo, kwakunye sisombululo engenazintsholongwane of medicament, agalelwa ezineengqayi ka-0.2 no 0.4 iilitha. Kuba unyango lwezifo ezininzi izicelo ngamafutha-5 ne-10 pesenti, kunye suppositories, eziqulathe 0.1 iigrem esisebenza (procaine hydrochloride), kwakunye amacandelo abangabancedani - witepsol okanye tallow. Ngowe-1 ml i into esebenzayo eziqulathwe kule mali ka-0,005 grams, amacandelo ezongezelelweyo benza zehydrochloric acid kunye namanzi ngenaliti.

Ubungqina obubonakalayo buxela

"Novocaine" imiyalelo Drug zokusetyenziswa bayakhuthazwa ukuba bonyule ukwenza retrobulbar, terminal, umnqonqo, ucingo, ebulewe, nokungena zomzimba. Ukusebenzisa imveliso vagosympathetic medicament kunye kwafa perirenal jugular. Ukusetyenziswa koMgaqo-suppository liyasebenza ukuba analgesia kunye ehlola ezimpundu kunye haemorrhoids. Ukusebenzisa linamafutha yabangela iimpawu neurodermatitis, nangokhwekhwe, ukurhawuzelela dermatosis.

Medicine "Novocaine": imiyalelo yokusebenzisa

Iinaliti izigulane abadala njengoko kwenza nokungena zomzimba zibe ngumqulu ka 300-600 mg (0.25-0.5 isisombululo pesenti).

Tight ngokuthi ezirhubuluzayo nokungena inkqubo Wisniewski lwenziwa ngokuthi unike isisombululo 0.25% xa isixa ml 125. zomzimba ebulewe lwenziwa ngoncedo "Novocaine" solution-amabini ekhulwini. Inaliti guide lithethelela ukuba umthamo ml-25. zomzimba spinal ezifunyenwe 2-3 ml-5% iziyobisi. Ngo-ENT umkhuba-10% of sisombululo zeziyobisi sisetyenziselwa Ukubulawa mlonyeni.

Ukwandisa ixesha yintshukumo neziyobisi nokunciphisa absorbability yalo, kananjalo kwi ichiza "Novocaine" lokudoma exutywe nesisombululo epinephrine hydrochloride. Ukuze enze electrophoresis Kucetyiswa ukuba basebenzise i-10% iziyobisi. Amafutha perirenal xa kuvalwe iindlela Wisniewski kufuneka ufake ml 60 okanye 120 ka-0.5-th okanye 0.25% isisombululo, ngokulandelelana. ukuvimba Vagosympathetic eziveliswa ukungenisa 100 ml imveliso ye 0.25% ingqalelo.

Nangona Izimo iinaliti "Novocaine" abantwana badla emiselweyo iintlungu ngexesha kulawulo amanye amayeza. Umthamo libalwa ngokusekelwe ubunzima umntwana (hayi milligrams ngaphezulu kwe 15 kilogram ngalinye).

suppositories efakwa zisetyenziswa emva eyenziwa ngaphambili purgation nge enema okanye ngokwendalo. Xa isikhumba ezimbi ngamafutha isicelo umaleko obhityileyo achaphazelekayo iquka izihlandlo ezibini xa enkqonkqoza.

imiphumela emibi

Drug "Novocaine" (imiyalelo zokusetyenziswa zilumkisa le) kunokubangela basabele embi.

Central kunye nenkqubo neuropathy luvo uphendule amayeza intloko ebuhlungu, ubuthathaka, ukozela, isiyezi, iveze, ukuxhuzula. Kwezinye iimeko, kukho lafa, ilahleko osezingqondweni, lockjaw, ukuva ongaboniyo, paraesthesia, ukushwabana imilenze, nystagmus. Ukongeza, kusenokubakho ukukhubazeka yokuphefumla, evalela i izihlunu zemiphunga.

inkqubo Cardio nemithambo utshintsho wegazi, kukho iintlungu esifubeni, arrhythmia, bradycardia, ukuwa, vasodilatation neuropathy.

Iinkqubo wokuchama esiswini besabela ukusetyenziswa iyeza Ukuchama ihlale kuyo, defecation, ukugabha kunye isicaphucaphu.

Ngomhla inxalenye yenkqubo yokujikeleza yeziphumo ebezingalindelekanga ziquka methemoglobinemia. Ukongeza, ichiza kunokubangela negazi lakho:

• ezindlwini;
• anaphylaxis ;
• ufunga kwesikhumba;
• ukulunywa.

Kuba abanye abasabela embi ziquka zomzimba ezingisayo, namandla, emzimbeni, iqolo. Ngexesha Ukubulawa woogqirha bamazinyo waphawula kungoluka zomzimba, paresthesia kunye antsi imilebe nolwimi.

libanda

Ukuze usebenzise i "Novocaine" kagqirha kweziyobisi, nto leyo ibonisa irejimeni yonyango kufuneka amiselwe ngugqirha. Ukungaphumeleli ukuthobela imimiselo ukuze ibe Imiqondiso yokuba libanda. Iimpawu yokusetyenziswa ngokugqithisileyo le medicament zezi pallor ye kwiinwebu nesikhumba integument, methemoglobinemia, umoya, uxinzelelo drop ngesiquphe, tachycardia, ukuphelelwa umoya, ukugabha, ukubila ezibandayo, isicaphucaphu, ukuba nesiyezi. Izigulane kufuneka nemvo yokoyika, motor ukuphazamiseka, unditsho, nemibono. Ukwenzela ukuphelisa izenzo libanda, kuyimfuneko ukuba enze umoya yemiphunga kunye oksijini inhalation, kwiimeko ezinzima, amisele kwangumqondiso kunye nonyango ubuthi.

Izimo

Ukusetyenziswa ichiza ukuze zonke izigulane. Xa inkqubo zomzimba lithintela ezihamba arhente nokungena utshintsho zeethishu fibrotic. Subarachnoid zomzimba ayikwazi ukuba wenziwe septicemia, Njengokungeniswa ithi, hypotension, ukopha. Ayikhuthazwa tu into yokuba nenxaxheba unyango sesikweni, umzekelo, enze cutha with "Novocaine".

Ulungiselele ngenyameko kusetyenziswa ngexesha lomsebenzi kwizigulane kunye etsolo ukopha, ukusilela kwezintso; kuba iimeko ezibandakanya ukuncitshiswa igazi hepatic, igazi phambili kunye insufficiency nemithambo; phezu usulelo kuyo inaliti; ezimbi arhabaxa. Phantsi kweliso zonyango ezizodwa kuyimfuneko ukusebenzisa amayeza ngexesha lokuzalwa komntwana, izigulane enzima ephelile, abantu abadala kunye nabantwana abangaphantsi kweminyaka uninzi.

Kunye amayeza kudityaniswe anticoagulants ( "danaparoid" "Warfarin", "Ardeparin", "dalteparin", "Enoxaparin" "lweeHedfowuni") kwandisa umngcipheko ukopha. Ukuhlisa uxinzelelo kunye bradycardia waphawula ngexesha ulawulo ngaxeshanye amayeza amayeza "trimetafan", "mecamylamine", "guanadrel", "guanethidine." Ukwandisa izenzo lokudoma imali "Epinephrine," "methoxamine", "Phenylephrine."

Iimpawu ze isicelo

Phambi kokuba ukuxuba "Novocaine" kwaye wenze shot, kufuneka ukuba ukufumanisa uvakalelo ngamnye amayeza. Ukuze wenze oku, enze uvavanyo eluswini, kwaye ukuba kukho ububomvu kunye kukufukuka inokubonwa umntu ukungazamkeli ithetha.

Ngexesha unyango kuyimfuneko ukuba esweni ukusebenza iinkqubo sentliziyo, Wayesoyika sokuphefumla. Ukunciphisa ukuba sesichengeni systemic, zinetyhefu nokunyusa isiphumo ichiza ngexesha zomzimba wasekuhlaleni, iziyobisi "lidocaine" okanye "Novocaine" lisetyenziswa kunye vasoconstrictors. Ngenxa yoko, omnye nethontsi sisombululo epinephrine hydrochloride lafakwa ml 3 medicament "Novocaine".

I inyuka xi yesisombululo esetyenzisiweyo, kokukhona ke ichiza ityhefu. Ukunciphisa imikhosi ifuthe kucetyiswa ukuba ukunciphisa idosi iyonke medicament okanye exutywe ukuya yoxinaniso asezantsi. Oku kwenziwa walaliswa nesisombululo isotonic sodium chloride.

Ukuvimbela sokungamelani hypersensitivity sikwinqanaba lokuqala onyango ezilawulwa 2 ml isisombululo-amabini ekhulwini, yaye emva kweentsuku ezintathu (ukuba akukho iziphumo ebezingalindelekanga) ithamo lanyuka ukuya 3 ml, yaye koko ukusebenzisa umthamo ngokupheleleyo - 5 ml inaliti nganye.

Ngexesha unyango izigulane kufuneka ukuba ayeke ukuqhuba kunye nozalisekiso lwemisebenzi enxulumene ingqalelo engakumbi, isantya kweemoto kunye abasabela engqondweni.

Intsebenziswano kunye namanye amachiza

Xa kulawulwa yegazi, ichiza kuphucula ukusebenza inhibitory kwi nadlamkisayo luvo, ipilisi zokulala, izixhobo ezisetyenziswa zomzimba jikelele, okudambisa kunye analgesics ezidakumbisayo. Ichiza lwenze intshukumo zihlunu, nemithambo block okubangelwa suxamethonium. Umngcipheko hypotension linyuke ukusetyenziswa idibene imali "Novocaine" nge Mao inhibitors).

Anticholinesterase amachiza ukwandisa ubuthi ichiza, zinqanda haydrolisis yayo. Para-aminobenzoic acid, nto leyo metabolite beziyobisi, kunciphisa isiphumo elwa of sulfonamides, ngokuba abayikhethayo ochasene kukhuphiswano. Amathuba abasabela basekuhlaleni ngohlobo nokudumba nokudodobala kwanda izitofu isithuba processing of lolawulo lokudoma nge izisombululo zintsholongwane equlethe enzima.

Ukusetyenziswa "Novocaine" iziyobisi ngexesha lokukhulelwa

Ngexesha ukuba nomntwana abafazi abaninzi senze imfuneko zamazinyo okanye iimpawu ezahlukeneyo ntle, ezifana iqolo. Xa bamazinyo, zomzimba elisetyenziswa ngokufuthi lithetha "Novocaine". Ukusetyenziswa kweziyobisi kwezi meko kwamkelekile. Kufuneka kuphela ukwazisa ugqirha wakho malunga nokukhulelwa ukuba wasebenzisa iziyobisi, kuthathelwa ingqalelo imeko yangoku. Xa toxicosis, kokuqhubela utshintsho wegazi, njengoko amayeza kuvunyelwa "Novocaine". Xa bekhulelwe, ukusetyenziswa kwayo kunokwenzeka kuphela xa uxinzelelo ophakamileyo, emva kokubonisana angaphambili kunye nogqirha.

Isixhobo lula umsebenzi wentliziyo kunye nefuthe iphumle phezu izihlunu. Xa iimpawu iintlungu esiswini, ezo ezinxulumene nesifo isilonda Peptic, sincoma ukusetyenziswa suppositories. Bunjani hemorrhoids kontanga nakho kunokwenzeka usebenzisa suppositories. "Novocaine" Drug lisetyenziswa ngexesha lokukhulelwa kuphela kagqirha, ukuzeyisa iyeza akuvumelekanga! Yingcali uzakubala ithamo efunekayo namatyeli kulawulo, emva kokuhlalutya izalathisi yokukhulelwa. Suppositories asetyenziswa kabini ngosuku, pre-msulwa umzimba nge enema.

Ixabiso kunye neziyobisi analogue "Novocaine"

Iindleko "Novocaine" ukulungiselela (ixabiso zisenokuthi zahluke kancinane ezikhemisti ngamnye) e ezineengqayi (0.5%), yi-22 engange. Per isitsha 0.25% isisombululo (200 ml) okanye suppositories efakwa kukunika 27 engange. nucleoside noshowo kwento ephilayo imithi:

• "Hydrochloride Procaine".
• "Base Novocain."
• "Novocaine-igutyana".
• "Novocaine Bufus".