Analogs "Atoris": inkcazelo, izimvo

Drug "Atoris" ababhaliswe iimveliso yenkampani Slovenian zoxubo "KRKA". Luphawu kunye nefikelelekayo generic "atorvastatin", nto leyo ngaphambili wathengisa kuphela ichiza ka Pfizer 'Lipitor'. Okwangoku, analogs zawo ( "Atoris", "Torvakard" kunye nabanye) baye babe yinxalenye yokusebenza zonyango kunye nomgangatho zingabameli hypocholesterolemic.

kunikezelo

Ukulungiselela "Atoris" ifumaneka emacwecweni kwiyunithi iidosi ezintathu. Oku 10, 20 no-40 mg. Kuthengiswa iibhokisi, kunye yokuhlala emacwecweni blister. Umthamo iibhokisi 10, 30 no 90 'Atoris "iipilisi (umyalelo manual). Analogs iziyobisi generic kwaye ziqulathe izixa twatse nombhalo wenkqu esebenzayo, kodwa abe neziphumo ezifanayo ngenxa yokungafani kumacandelwana.

Ichiza "Atoris"

Le into esebenzayo yi atorvastatin, statin III ngezizukulwana. izinto zoncediso zezi zilandelayo: Polyvinyl utywala, titanium dioxide, macrogol 3000, nemagnesium stearate, talc, isodiyam croscarmellose, microcrystalline kwincindi, monohydrate lactose, povidone, calcium carbonate, sodium lauryl sulfate.

Excipients sizimisele ifomu idosi tableted kwaye amisele izinga atorvastatin kukufakwa egazini. Ngoko, naziphi na iziyobisi analog "Atoris" kufuneka siqulathe isixa ofanayo into esebenzayo akhululwe kwaye ngesantya enye, ukudala efanayo lamanani igazi.

Ethethelela statins kunye neziyobisi "Atoris"

Ukulungiselela "Atoris" njengoko into esebenzayo iqulathe atorvastatin. Ku fanele ukuba udidi arhente wesithathu-ngezizukulwana. Ngayo kubanjwe ezininzi izifundo eziye yaqinisekisa ukuba nokwenzeka yokwamkela yayo phambi imiba yamafutha ubungozi okanye sele kuphuhliswa esi sifo. "Atorvastatin" analogs, "Atoris" kunye nezinye statins ziyakwehlisa ngokubonakalayo isakhono lipoproteins ingxinano ephantsi (LDL) kubangele yamafutha kwaye kungakhokelela ekubeni okubi yayo. Oku ixabiso labo lwezonyango, kuba kunye nokubandakanyeka kwabo ngqo kunciphisa izehlo yokuhlaselwa sentliziyo.

imiphumela kwemithi

Isiphumo ibalulekileyo efumene yaphambana cholesterol kudibaniso nge ziyibuyisela umva le enzyme HMG-onx reductase. Ngenxa yoko ukupheliswa okanye ukuncitshiswa ebalulekileyo Yindibanisela LDL. Le iqhezu lipoproteins bandiqumbise yegazi, esasibangela ukuvala eludongeni kunye itywina yalo imithambo intliziyo, ingqondo kunye asezantsi omzimba. Kunye ukuncitshiswa LDL kwandisa lwee- lipoproteins ache.

Benza umsebenzi obalulekileyo: landa ukumelana inwebu kwiimpembelelo koomatshini nemichiza ngenxa sokubandakanya cholesterol kuyo. Ngenxa yoko, HDL ilahlwe, kodwa musa yande cholesterol. LDL ikhokelela nokwanda yayo emva endothelium semithambo, ibangela kwemithambo yegazi, ngelixa lipoprotein cholesterol lwetshiphu emsebenzi-mninzi iidipozithi ukunciphisa izinga, kodwa musa imveliso kwi iqokobhe kwemithambo uhlobo engaphakathi elastic.

Umthamo "Atoris" ukulungiselela

Izindululo ukuba ayinonophele njani "Atoris" ubilisa phantsi ukucacisa ezinye iinkalo. Ngokukodwa, beziyobisi sidlalwa kumhlaba idosi emiselweyo kanye yonke imihla emva kwesidlo sangokuhlwa phambi kokuba uye kulala. A idosi enye ingaba 10, 20 no-40 mg. Ekubeni ichiza amayeza ngokuthenga walo kufuneka udibane nogqirha. Ukuba emva nasekuhlalutyeni amaqhezu profile lipid kwinqanaba yegazi iyonke uyakwazi ukuncoma idosi echanekileyo atorvastatin kunye analogs zayo okanye udidi oluthile.

Xa Kucetyiswa cholesterol kokuqala 7.5 okanye ngaphezulu ukuthatha 80 mg / ngosuku. oyidlayo afanayo achazwe kwizigulana abathwaxwa a iposi engabalulekanga okanye kwinqanaba nokoyika indima yawo. Xa iqela 6.5 ukuya yedosi 7.5 esiconywayo 40 mg. 20 mg xa inqanaba cholesterol 5.5 - 6.5 mmol / ilitha. 10 mg beziyobisi ezifanelekileyo abantwana ukusuka kwiminyaka eli-10 ukuya ku-17 kunye hypercholesterolemia heterozygous, kwakunye nabantu abadala hypercholesterolemia ephambili.

Iimfuneko generics

Qualitative analogu kulungiselelwa "Atoris" kufuneka ibe nezilishumi efanayo esisebenza kunye nokudala efanayo lamanani igazi. Ngaphandle kokuba indlela enjalo, uthathwa ukuba bioequivalent kwaye indawo yokuqala ngokupheleleyo. Malunga ichiza "Lipitor" i-analogue of "Atoris", wadala ngokusekelwe atorvastatin.

Iimfuneko nucleoside lwezonyango "Atoris"

Nayiphi endaweni "Atoris", iklasi okanye elingana kumafa, kufuneka iqulathe naluphi na statins. Kulo mzekelo, oko zingasetyenziswa njenge elilingana ngokupheleleyo. Ngaphezu koko, ukutshintshwa "Atoris" ngamachiza kwi-analogu kufuneka wenziwe idosi ekujoliswe kulondolozwe. Ukuba usebenzisa 10 mg "Atoris", ngoko kwelinye ichiza kufuneka kwakhona ibe umsebenzi enye okanye ngaphezulu.

Kawonk-wonke "Lipitor"

Ekubeni atorvastatin original yi "Lipitor" zonke iziyobisi kunye isithako efanayo esebenzayo kufuneka azilingani naye. Analogs, "Atoris" phakathi kwawo kakhulu elungeleleneyo kwixabiso, kufuneka zithathelwe ingqalelo kule mbono. Ngoko ke, kukho imithi loo Ixabiso eliphezulu, ungathatha kunye elisezantsi. nucleoside Full "Atoris":

• eninzi ( "Lipitor");
• ukufikelela ngokulinganayo ( "Torvakard", "eTulip");
• zitshiphu ( "Lipromak", "Atomaks", "Lipoford", "Liptonorm").

Njengoko kubonakala, analogue atorvastatin bamelwe ngokubanzi. Baninzi kakhulu zinikelwe ixabiso kudidi eliphantsi. Oku kufuneka kubandakanye kakhulu amayeza kunye negama lorhwebo "Atorvastatin", ezo ziveliswa phantsi mvume kwiinkampani ezinkulu ezixuba amayeza.

Ukuba sifuna ukuba kwiwotshi of "Atoris" atorvastatin enganeno yiyo nayiphi na imveliso yasekhaya phantsi mvume. Kakhulu ophezulu ezikumgangatho kunye nokuthotyelwa ngokupheleleyo kunye oluchazwe yi "Atorvastatin" Borisov nasemifunweni imithi, use Belarus. Apha, ukuveliswa ichiza ilawulwa yi KRKA, yona "Atoris".

Iimpawu beziyobisi lokutshintshwa

Ngomhla umbuzo wokuba yintoni endaweni "Atoris", kubalulekile ukuqwalasela iimeko ezininzi. Okokuqala, ichiza kufuneka ayasebenza efanelekileyo lwezonyango kunye zivunwe kakuhle. Okwesibini, ixabiso layo kufuneka esezantsi, okanye ukuba udidi ichiza inxulumene analogs kancinci ngasentla. Okwesithathu, ithamo yangaphambili kufuneka ilandelwe, ukuba indawo senziwa kwi ozingenelayo. Kwimeko inguqu ukuba analogu lodidi isiyobisi kubalulekile ukuba ufumane idosi elingana.

Ukufakwa for generics

Phakathi amalungiselelo eziqulathe atorvastatin, zezona zinto zilandelayo kakhulu qualitative: "Lipitor" "Torvakard", "Lipromak" yaye "Atoris". Analogs, izimvo zalo zinqabile, obuphantsi kwabo ukusebenza kunye nokhuseleko. Nangona ke kukhetha ixabiso. Zingakotshwa Kucetyiswa ukuba izigulane ongakhathaliyo malunga bioequivalence lwe generic okanye akafuni overpay. umahluko obonakalayo isiphumo oku anayenza, nangona umgangatho unyango othile ochaphazelekayo.

Ukuba sicinga atorvastatin generic, kucetyiswa ukuba ukhethe phakathi ngasentla. Kodwa ke, umzekelo, ukuba isigqibo ukukhetha - akukho lula, "Atoris" okanye "Torvakard". Isizathu soku ke ukuthotyelwa phantse epheleleyo kunye la machiza ixabiso kunye nokusebenza. Ngaphezu koko, ixabiso nalo rhoqo efanayo. Ngasentla kubo umgangatho "Lipitor" yaye ngezantsi - "Lipromak". Ngelo xesha linye lokugqibela, kunye umahluko okungephi izinto, ifikeleleke ngakumbi.

Ezitshintshwayo nabalingani class "Atoris"

Xa Elungiselela "Atoris" analogue e Ukraine kunye namanye amazwe ico, kukho nazo eklasini. Oko kukuthi, ukulungiswa iqulathe omnye statin, ngokulandelelana, ezineempawu ezahlukeneyo. Utshintsho enengqondo "Atoris" kwi "pitavastatin" okanye "Rosuvastatin" abanesidanga kancane LDL lisibekele. Le yokugqibela zikhuselekile yaye kunempembelelo kwezonyango kwi idosi esezantsi.

nabalingani ngaphambili, kukho kwakhona "Atoris" Kukhethwa ngakumbi xa kuthelekiswa nabo, nangona zibe nefuthe lwezonyango ngokupheleleyo. Umzekelo, "Simvastatin" - siyobisi ezifikelelekayo kunye eqinisekisiwe ukhuseleko yolingo lwezonyango. Lo mthombo original 'Zocor'. Xa siqwalasela kufikelelekayo kunye nomgangatho isizukulwana yokugqibela statin abe lilalela "Atoris", kungcono ukuthatha umzekelo, "Merten". Oku akukho ngaphantsi bafunda "Rosuvastatin" ngokubanzi kunye ngexabiso efikelelekayo.