Ichiza "Gynestril": imiyalelo ukusetyenziswa, analogs kunye nohlolo

Indlela ukuthatha ichiza "Gynestril"? Imiyalelo yokusebenzisa le iyeza iza kuchazwa izinto kweli nqaku. Kuyo, sinikela iimpendulo yezigulane, ichiza, iimpawu zayo amayeza, kubonakala kunye Izimo.

Ukubunjwa, imilo

Ziziphi amacandelo kuquka amayeza "Gynestril"? IMimiselo olubekwe le ndlela, oko kukuba zithako wayo asebenzayo mifepristone. Kwakhona le medicament liquka izithako owongezelelweyo ngendlela amazambane wesitatshi, lactose, microcrystalline kwincindi, povidone, nemagnesium stearate kesodiyam carboxymethyl istatshi.

Thenga le kungaba emacwecweni, apho zipakishwe ngendlela kwimiqulu kwikhadibhodi.

iimpawu imithi imithi

Ngaba ubusazi ukuba sisiyobisi "Gynestril"? Imiyalelo yokusebenzisa iya kukunceda uqonde umgaqo amanyathelo kweli chiza, kwaye baya kukuxelela ukuba phantsi akukho ezibonisa ukusetyenziswa kwayo yezonyango.

medicament kujongwa i arhente steroid antigestagens imvelaphi zokwenziwa. Ukusebenza therapeutic beziyobisi ngenxa nokubunjwa kwayo.

Zakuba zifikile mifepristone emzimbeni womntu ngayo abangaphangeliyo iimpembelelo dlala, kodwa ukubonisa umsebenzi progestational.

Iingcali qaphela kwingcinezelo ichiza ngenxa yokhuphiswano kunye glucocorticoid iyabophelela kwinqanaba receptor.

Njengoko yaziwa, indima ephambili ebangela ukuba kusekwe zesibeleko leiomyoma enikwa iihomoni ababhinqileyo, ingakumbi yiprogesterone. Kule nkalo, mifepristone linokukwenziwa nomntu ogulayo ukuvimba receptor yiprogesterone. Ngenxa yale mpatho kwenzeka kokulibazisa ukukhula ithumba, kwakunye nasekunciphiseni ubungakanani fibroids , kunye zesibeleko.

Iimpawu pharmacokinetic ye ichiza

Ziziphi iinkalo na ichiza pharmacokinetic "Gynestril"? Imiyalelo, ncomo bafumana oogqirha bathi emva ulawulo yomlomo ukufumaneka eliphezulu ichiza wayiphawula malunga 80 kwimizuzu. Ngaphezu koko, bioavailability yalo 69%.

iziyobisi iiproteni Plasma ingqalelo enebana 98% (kunye albumin kunye alpha-1 acid glycoprotein).

Emva kwisigaba unikezelo kwenzeka kwisigaba ukususwa kade. Egazini uyondelelwano lwee- ichiza yehliswe ngesiqingatha (phakathi kwe-15 ne-72 iiyure).

Ukuphelisa ichiza okukhawulezayo, kunye kwisithuba kweeyure eziyi-18.

Ubungqina obubonakalayo buxela

Ukusuka apho ichiza "Gynestril" linokukwenziwa? Imiyalelo yokusebenzisa, iingcaphephe yokwenene zibonisa Yayibubungqina zilandelayo:

• unyango lwe wesizalo leiomyoma;
• ukupheliswa ukukhulelwa intrauterine ukuya kwiintsuku 42;
• yoqheliso (okanye ukukhuthazwa) yabasebenzi (kubandakanywa i-term);
• kukhulelwa zexesha likaxakeka (postcoital) ukwenzela unreliability kusetyenziswa ukukhulelwa, kwaye kwithuba emva neentlobano zesini engakhuselekanga.

Izimo

"Gynestril" yeziyobisi isithuba isisu kufuneka ingasetyenziswa xa:

• ukukhulelwa ngokwezonyango engaqinisekiswanga;
• pregnancy kuvumelekile;
• ukukhulelwa ezivele emva ukurhoxiswa iindlela hormone zokuthintela ukukhulelwa, okanye ngokusebenzisa i yokucwangcisa intrauterine;
• ukukhulelwa emva kweentsuku 42.

Xa leiomyoma eli chiza akuvumelekanga ukuba abele kwezi meko zilandelayo:

• ebeka komse- myoma submucous;
• e yamathumba ovarian;
• hyperplasia endometrial;
• ukuba ixabiso leiomyoma inkulu.

Amacwecwe "Gynestril" ngenxa yoqheliso yabasebenzi alisetyenziswa:

• yokukhulelwa kakhulu;
• intshumayelo Palsy engaqhelekanga;
• pre-eclampsia;
• eclampsia;
• njengokuzalwa okanye post-term nokukhulelwa;
• ukungalingani ubukhulu foetal intloko kunye noomama isinqe;
• amabala akubonakali evela iphecana angasese ngexesha yokumitha.

Ngaba jikelele Izimo iziyobisi "Gynestril"? Imiyalelo unika lo mbuzo affirmative. Ezi imingcele ziquka miqathango ilandelayo:

• porphyria;
• unyango lwexesha elide kunye glucocorticoids;
• igazi kakhulu;
• kwezintso okanye ukusilela isibindi (kulo naluphi na uhlobo);
• kophulwa umthetho hemostasis (unyango elidlulileyo anticoagulant);
• extragenital sina;
• ngezifo kwenkqubo ababhinqileyo okuzala, nto leyo isimilo arhabaxa;
• hypersensitivity (kuquka imbali);
• nikotinozavisimost, ingakumbi emva kweminyaka engama-35.

Ngononophelo kakhulu xa ukuthatha eli yeza:

• Izifo obstructive pulmonary (umlinganiswa ezingapheliyo);
• Ukungaphumeleli intliziyo;
• wegazi;
• arrhythmia;
• isifuba inyumoniya;
• nokuphazamiseka intliziyo isingqisho.

Drug "Gynestril": mazwi

Kuba eyeka lokukhulelwa (reviews nomonde yale medicament kuya kuxoxwa kancinane ngakumbi), eli chiza kufuneka anikwe ingcali elimxinwa kuphela. Ugcine ukuthatha iipilisi kulo mzekelo kuphela xa kukho ugqirha.

Ekubeni ukusebenzisa iziyobisi "Gynestril"? Imiyalelo ukukhulelwa ukupheliswa ithi ukuba kuyimfuneko ukusebenzisa nedosi enye ye-600 mg.

Ichiza esithatyathwe iiyure 1-1.5 emva kokutya kunye kwehle nge-100 ml yamanzi.

Ukwandisa ukusebenza ichiza ukuze injongo ngakumbi 400 mg misoprostol (ngamanye amazwi, prostaglandin eyenziweyo E1).

Emva kokufumana amacwecwe isigulane kufuneka bagadwe obstetrician iiyure ubuncinane ezimbini. Emva kweentsuku 1.5 okanye 2 wenziwe ultrasound. Kwanasemva kokuba kwiiveki 1-2 ukuqhuba uviwo lwezonyango kunye ultrasound waphinda khangela amanqanaba igazi hCG ukuqinisekisa kwesisu.

Xa kunjalo, ukuba ichiza zange kunceda (oko kukuthi, uyaqhuba ukukhulelwa), ugqirha lithethelela ukuba cleaner ngeminqweno kufundisiso phambili (histology) iziphumo zale nkqubo.

Ukuze sikhuthaze imisebenzi generic, ichiza kanye inokusetyenziswa ngendlela of mg 200. Benza oku kukho ugqirha. Emva kosuku olunye, ithamo amayeza iphindiwe kwi idosi enye.

Emva kweentsuku 2-3, ukuqikelela ukwandiswa emjelweni wokuzalwa. Ngoko ke ithuba ukusetyenziswa ngakumbi "yioxytocin" okanye prostaglandins.

Ke ukuba ukusetyenziswa kweziyobisi leiomyoma zesibeleko "Gynestril"? Guide uthi xa ukulungiselela loo uphethwe esuke kwi nedosi enye ye-50 mg. Ichiza ithathwa ngomlomo iinyanga ezintathu.

Ngokumalunga nzala post-coital, oogqirha bacebisa ukusetyenziswa medicament kuqwalaselwa kwi-mali ka-10 mg iintsuku ezintathu emva kokuba neentlobano zesini engakhuselekanga (nokuba isigaba exesheni). Ukuthatha iipilisi kule meko kuyanqweneleka iiyure ezimbini ngaphambi okanye emva kokutya.

amacala libanda

Sebenzisa beziyobisi xa umthamo we akukho grams ngaphezu ezimbini kwiimbangi naziphi na iziphumo ezingalunganga. Xa usebenzisa ngaphezulu kwama-mali ezichaziweyo amayeza isigulane kuyaba insufficiency adrenal, esifuna unyango nomqondiso.

imiphumela emibi

Ukufumana medicament "Gynestril" lidla ibanga iziphumo ebezingalindelekanga ezifana intloko, isicaphucaphu, isiyezi, ukugabha, irhashalala, urhudo, amenorrhea, lohiometra amabala, zesibeleko subinvoljutcija, nokushisa, emmeniopathy, ukutyhafa, ukudandatheka na ukudumba wesibeleko kunye ezihlobene, ubuhlungu kunye neentlungu esiswini. Ukuba ngaba wehlelwa zezi mpawu, qiniseka ukuba udibane nogqirha.

imithi

Akuyi Kucetyiswa ukuba ichiza "Gynestril" ngokunxuseneyo kunye NSAIDs. Kufuneka kuqatshelwe ukuba zidityaniswe kunye glucocorticoids kuyimfuneko ukwandisa umthamo, kodwa ke kuphela emva kokudibana nogqirha wakho.

izincomo ezithile

Ayikhuthazwa ukuthatha iyeza njengokuba ukukhulelwa rhoqo.

Xa usebenzisa i "Gynestril" Ukuqhomfa kufuneka kusoloko azise isigulana malunga nezinye iinketho kule nkqubo, ingakumbi xa emva kweeveki ezimbini ukukhulelwa siyaqhubeka okanye kukho isisu ezingaphelelanga (ingozi ezingaqhelekanga kwi olungekazalwa).

Ixabiso kunye analogue imali

Analogs "ulawulo Gynestril" beziyobisi ezi amayeza zilandelayo: "Ginepriston", "Penkrofton", "Agesta" "Mifepristone", "Zhenale", "Mifolian", "Mifegin", "Mifepreks", "Miropriston".

Price ingqalelo iziyobisi eliphezulu kakhulu kwaye kuthetha 5000-6000 engange.

Izimvo medicament

izimvo nangokungenamathandabuzo kwindlela ethile entle okanye embi ngayo "Gynestril" akukho ukulungiselela. Noko ke, abantu abaninzi basabela kakuhle ngayo esi sixhobo. Bathi ukuba zisebenza kakuhle kakhulu kwaye nendlela ekhuselekileyo ukulungiselela ulwamkelo.

Kufuneka kuqatshelwe ukuba abanye abantu, phezu koko, ngokufuthi ambona kuphuhliso yeziphumo ebezingalindelekanga.

Zonke ezi ukubuyekeza zibonisa ukuba ukuthathwa olu nyango kufuneka kwenziwe kuphela emva kokubonisana nogqirha.