"Ibuprom": imiyalelo, real

amachiza Nonsteroidal anti-ukudumba babe ngabantu abakwizihlalo ephambili kwiimarike zoxubo zehlabathi olomeleleyo. Ezi zixhobo kufuneka nefuthe entsonkothileyo legalelo antipyretic, anti-ukudumba kwaye iintlungu emzimbeni womntu. Enye imithi enjalo yi "Ibuprom". Okufundisela silawula njengendawo loncedo lwesiphumo kakhulu ngenxa yezizathu ezininzi ezahlukeneyo izifo.

pharmacodynamics beziyobisi

"Ibuprom" imele acid ithe phenylpropionic. Le ndlela isekelwe kwezithandani lomsebenzi impembelelo Cox (enzyme, ukuba siphu- prostaglandins, nto leyo kulawula inkqubo Pathogenesis, uphuhliso ubuhlungu kunye febrile). Apho medicament ekuso ukuba inhibition non-akhetha cyclooxygenase, okt "Ibuprom" abangaphangeliyo ngokulinganayo umsebenzi zombini isoforms ye-enzyme - .. Cox-1 Cox-2.

Isiphumo iintlungu imiyalelo "Ibuprom" iziyobisi zokusetyenziswa ebangela iindlela ezimbini - neuropathy central. Pevy kubonakaliswa ngokungangqalanga inhibition benkqubo yokwenza imveliso prostaglandin. Isiphumo indlela yesibini (central) kukuba ukucinezela kwisizukulwana prostaglandins kule mimandla kumbindi neuropathy ye-NA. Ngenxa ekunciphiseni komtshiso lipid langoku izinto physiologically esebenzayo kunciphisa-ethe-receptors umbono nokushukunyiswa imichiza. Xa iziko thermoregulation ngxenye kwi kwezithandani of prostaglandin amagama kukhokelela ekuncipheni lobushushu emzimbeni ithi xa bomkhuhlane.

Ukongezelela, "Ibuprom" iipilisi (umsebenzisi A ukulungiselela siqulathe ulwazi) ukusa kumkhamo othile zinqanda udibaniso (lib) of ziiplatelets.

Ukubunjwa kunye nefomu yokhululo iziyobisi

Ibuprofen - amaqela esebenzayo engundoqo "Ibuproma". Njengokuba amacandelo abancedisayo ingabizwa crospovidone, lesilicon dioxide, polyethylene ethers kunye nenani kwezinto (awu, starch, oli yemifuno, sucrose, kunye m. P.).

Forms apho ichiza lwenziwa abathengi, ngaphezulu. Ukuqulunqwa kufuneka zipakishwe neepakethana e Polyvinyl igutyana (tablets-50) okanye kumadyunguza.

Kuxhomekeka umthamo icandelo ephambili ekuqulunqeni kuthethwayo "Ibuprome" (200 mg of ibuprofen tablet nganye) okanye medicament "Ibuprom Max '(400 mg ibuprofen). Kodwa loo nto bonke. On ezahlukeneyo ezifana "Spirit Ibuprom Capps" umyalelo isixelela ukuba medicament yenziwa ngo njengezingxobo 200 mg lomongo into esebenzayo nganye. "Extra Ibuprom" Kwakhona wanikela izigulane njengezingxobo, ivolyum icandelo eziphambili ngamnye - 400 mg. On "Ibuprom Sinus" manual uthi njengenxenye tablet liqulathe 200 mg ka-ibuprofen ne-30 mg pseudoephedrine hydrochloride.

Ubungqina obubonakalayo buxela

Inkcazelo zonke iimpawu ziya kufumaneka xa nemiphumo emihle, iquka ngeendlela ezifana "Ibuprom" Amacwecwe myalelo. Ukubunjwa (analogs medicament ineempahla efanayo esebenzayo ziya kuba malunga neziphumo ezifanayo), into ke leyo exela ukuba medicament unika iziphumo ezidibanisayo kwi unyango lwezifo ezifana naziphi na iingxaki umqolo yokukrala sisiba mandundu namalungu. Akukho ngaphandle isifo (samathambo, samathambo, psoriatic), osteoarthritis, ankylosing spondylitis. Yabela "Ibuprom" ithambile inyama nokudumba kunye nenkqubo musculoskeletal ezibangelwa trauma, radiculitis, bursitis, tendinitis. Ngaphezu koko, lo medicament uyakwazi ukumelana ebuhlungu kunye bamazinyo, neuralgia, myalgia, iintlungu syndrome kuzo izifo ezosulelayo kunye yokukrala phecana eliphezulu zemiphunga. Zisebenzi abenza wokumisa "Ibuproma" kwiimeko bomkhuhlane ukunciphisa ubushushu bomzimba, kunye uziva nokumodareyithwa tyhafi ngcathu intlungu kunye nemvelaphi engaziwayo.

"Max Ibuprom" yemiyalezo icebisa ukuthatha ubukho iimpawu ezifanayo xa umthamo ofunekayo medicament lwesamente. "Ibuprom Extra" baya kuba ngempumelelo iimpawu ezinjalo.

"Ibuprom Sinus" (ntonye - "Caps Ibuprom Spirit") idla ezimiselweyo ukubonelela iintlungu, antipyretic kunye nempembelelo anti-ukudumba, kwakunye nokunciphisa ekweneni kwiinwebu zempumlo kunye sinuses paranasal. Oko kukuthi, ichiza iya kuba nempumelelo na unyango kwangumqondiso njengomkhuhlane, izifo ezihlasela zosulele ngokuphefumla kwaye umkhuhlane kunye intloko ebuhlungu, umqala obuhlungu, izihlunu, icesina kunye ukudumba kwiinwebu impumlo kunye sinuses paranasal.

izicelo kunokwenzeka

"Ibuprom" (tablets) yemiyalezo lithethelela ukuba abele ngabanye ukuba isigulane ngasinye kuxhomekeke kubungakanani iimpawu kwezonyango sifo. Irejimeni eqhelekileyo ye ichiza - idosi enye zibe ngumqulu of mg 200 ukuya 800 emva kwesithuba amaxesha 3-4 ngosuku. Kuba izigulane kwencinane idosi ikhethiwe kuxhomekeke ubunzima bomzimba - 20-40 mg kwekilogram ubunzima bomzimba ngalinye (oku ngumthamo mihla), yahlulwe yaba izihlandlo eziliqela imini yonke. unyango ngokuqhelekileyo ithatha iiveki ezi-2 ukuya kwemi-3. Ubuninzi yedosi zokuba ngosuku ukuba isigulane omdala - 2.4 g yamkelwe ngexesha okanye emva kokutya kunye kwehle nge encinci ulwelo. Yahlula tablet ibe iindawo ezingafunekiyo.

"Max Ibuprom» ngokuzimela kokutya neziselo oko kufuna umthamo owaneleyo wamanzi. On yinxalenye yokwahlulahlula ipilisi ezingathandekiyo.

Ke ukuba i "Spirit Ibuprom Capps", ngoko ke kwizigulane engaphezu kwe-12 iminyaka umthamo ubudala ongatshatanga sele 1-2 njengezingxobo zonke 4-6 iiyure ekhefu. Yithathe ukutya ngexesha okanye emva. Kuba abantu abadala ngokukodwa khetha ithamo ayikho kuyimfuneko, ngaphandle kwakwiimeko ukusilela kubonakala umsebenzi wezintso kwaye zesibindi.

Kucetyiswa "Ibuprom ezongezelelweyo" umyalelo ukuthatha 1 philisi zonke iiyure ezi-4 (ukuthetha malunga izigulane kweminyaka engama-12), kodwa akukho njengezingxobo ngaphezulu kwe-3 ngosuku. Thatha amayeza emva kwesidlo, musa ayetyisi. Izigulane abakhulileyo ngokukodwa khetha ithamo ayikho imfuneko.

"Ibuprom Sinus" sathathwa phambi izidlo amacwecwe 1-2 nokuhlamba phantsi ngamanzi. Ubuninzi - qho kwiiyure 4-6. Ubuninzi imihla kuvumelekile ukuba uthathe iipilisi 6.

Izimo ukuba ichiza "Ibuprom"

"Ibuprom" (tablets) usebenzisa umyalelo uyakuthintela abo abe hypersensitivity olwandisiweyo ibuprofen okanye naziphi na izithako na isincedisi. medicament sabelo engamkelekanga ukuba izigulana izitshanguba wokugaya uhlobo ilunga-ezilinyaziweyo (ingakumbi kwisigaba oyingozi). Kwakhona engavunyelwa unyango "Ibupromom" phambi aspirin triad , kwaye kwezinye izifo luvo optic. Ngokwahlukahlukana umsebenzi kwinkqubo hemopoietic kananjalo isiseko non-ukusebenzisa naziphi na izixhobo ukusuka kwiqela NSAID. Not ekhona injongo yale chiza kwizigulane apho kukho ziphawulwe nezitenxo kwi nezintso nomhlehlo wesibindi.

Yinto engamkelekanga kwaye Application "Ibuproma" kunye namanye amachiza kwiqela non-steroidal.

Njengoko le heroin 'Ibuprom Max "iipilisi imiyalelo zokusetyenziswa uyakuthintela phantsi iingxaki ezifanayo, njengoko wenza i" Ibuprom ".

"Ibuprom Extra", ukongezelela zonke Izimo ezichazwe ngasentla, alikwazi ukugunyazisa ubukho ukopha diathesis kwizigulane kunye kumsebenzi ayonelanga inhliziyo. Kwakhona Awukwazi ukuthatha eli chiza eyayichasene emzimbeni bawuphikisa ukugabha, urhudo okanye ukuselwa ayanelanga fluid.

Xa ichiza "Ibuprom Sinus" zonke ngentla Izimo elimiselweyo. Ngaphezu koko, oko alisetyenziswa somoya, isifo seswekile, lengqula (giperterioz) imigangatho ephakamileyo hormone. Ngaba contraindicated kwizigulane phambi pheochromocytoma (yamathumba adrenal zomzimba), hyperplasia (adenoma) wendlala.

emibi

"Ibuprom" njengoko kunyanyezelwa? Manual iqulathe ulwazi amathuba kwezinye iziganeko ezibi ezivela kwiinkqubo ezahlukeneyo kunye ngokwamalungu izigulane abafumana ichiza. Eli nani likhulu iimpendulo ukusetyenziswa NSAIDs yi ndazigcina iphecana zesisu. Izigulane bethetha isicaphucaphu, ukugabha, ukungakhululeki epigastric, ukudla kunye nophuhliso izilonda ilunga ezilinyaziweyo le kwiinwebu lokugaya.

CNS iziphumo ebezingalindelekanga zidla waphawula ebuhlungu, isiyezi, ukuphazamiseka, ukungaqheleki ukulala kunye neenkqubo Ukunakana into ebonwayo. reactions icala kunokwenzeka krovetvoryaschey inkqubo emva kokufumana medicament ukuba elide isithuba - igazi, thrombocytopenia, agranulocytosis.

Kukho iindidi ngeendidi kukwalisa "Ibuprom". Iipilisi (umsebenzisi iqulethe iinkcukacha) ukuze bandiqumbise irhashalala, nokudumba angioneurotic. Kwiimeko ezinqabe kakhulu kunokubangela meningitis aseptic (kakhulu kalula lo bantu abasabela kunye nezifo samathambo), bronchospastic syndrome. Njengoko wabona wasekuhlaleni izigulane zithi malunga kuyabuya kunye wakube usiva unambuzelelo elivuthayo eluswini, malunga ingxinano.

"Ibuprom Sinus", ukongezelela zonke ngentla ezidweliswe, luwuphuphumise uphuhliso dyspnea, tachycardia, ophakamileyo uxinzelelo lwegazi, hyperhidrosis.

ngeedosi kakhulu: Implications

Kwimeko apho libanda, iziyobisi ezifana "Ibuprom" yaye "Max Ibuprom" yemiyalezo ingxelo uphuhliso isicaphucaphu nokugabha, iintlungu epigastric kunokwenzeka. Kwakhona, kwimeko enjalo Inokwenzeka ukozela, waziva intloko ebuhlungu kunye nesiyezi, ukuze ukunciphisa uxinzelelo lwegazi kunye arrhythmias. Kwiimeko kakhulu iimpawu kuvela lactic pathways Inokwenzeka ukulahleka ezingqondweni ne umsebenzi othile zemiphunga.

Kwiimeko ezinjalo bubulumko lavage engxamisekileyo esiswini kunye nokuqeshwa unyango nomqondiso. enterosorbents ngomlomo Kwenziwe. Bhija syndrome sirhoxisiwe nge "Diazepam", "lorazepam".

Ngenxa libanda of "Ibuprom Spirit Capps," ngaphandle zonke ngasentla, kukho amathuba nokudideka, ukuxhuzula, ukufa isiqaqa. isibindi kwekhono kunokwenzeka. Xa izigulane sombefu, kungaba kubi kakhulu sesi sifo.

iziyobisi ukusetyenziswa Long-term "Ibuprom Sinus" kunokubangela utshintsho zophendlo lwezifo egazini, ezifana kwegazi hemolytic (sokonakalisa balomeleza ngayo iiseli ezibomvu), granulocytopenia (ukuncitshiswa kwenani granulocytes), thrombocytopenia (amaqondo aphantsi zegazi).

Yintoni ekufuneka sinikele ingqalelo kuyo?

"Ibuprom" sikhokelo ikhuthaza mazithathwe ngokuqaphela kwabo Uyinxulumanise isifo sesibindi, isifo sezintso, ukusilela intliziyo esinganyangekiyo. Ukuba phambi kokuqala unyango isigulane impawu ukuqunjelwa, okanye isigulane babesanda uqhaqho, kananjalo kufuneka ukuba ukuqala unyango "Ibupromom" ngononophelo olukhulu. A imbali ulwazi nokopha naluphi na uhlobo kwezifo wokudla, ibonwa negazi, ezinxulumene-unyango nonsteroidal amachiza anti-ukudumba, kufuneka kwakhona ibe sisihlandlo ingqalelo imeko yomguli.

Ukuthintela iingozi, kuyimfuneko kwisicelo "Ibuproma" qho iliso umsebenzi kwezintso kunye wesibindi, picture igazi neuropathy.

Yaye "Ibuprom" yaye "Max Ibuprom" myalelo akukhuthazwa ukuba zisetyenziswe ngo-3 ezintathu ukukhulelwa. Xa trimesters 1 no-2 yokusebenzisa NSAID bugwetyelwe kuphela kwiimeko apho isiphumo kulindeleke elincumisayo unina komonakalo neziphumo ezingalunganga ezinokwenzeka ukuba umntwana.

Ibuprofen - icandelo esebenzayo engundoqo "Ibuproma" - ngeedosi ezincinane kwazona ngobisi lwebele, noko ngenxa isiqabu intlungu kunye neemeko bomkhuhlane isicelo sawo ngexesha zisanyisa kunokwenzeka. Noko ke, ukuba kukho umbuzo unyango lwexesha elide kunye ngoncedo "Ibuproma" okanye imfuneko ukufumana ngeedosi ezinkulu kufuneka uxoxe nogqirha wakho umbuzo nokwala ukuncancisa.

Besebenzisa "Ibuproma Sinus" kwi ixesha lokumitha ukukhulelwa kunye nencum-lwebele contraindicated ngokubanzi.

Intsebenziswano kunye namanye amachiza

Nayiphi na ifomu "Ibuproma" ( "Ibuprom Max", "Spirit Ibuprom Capps," "Extra Ibuprom") yemiyalezo uyakuthintela ngaxeshanye kunye antihypertensives kunye womchamo ezifana furosemide, hydrochlorothiazide, njengoko kokuba kakhulu kwanciphisa ukusebenza zabo zonyango.

Ukusetyenziswa "Ibuproma" ngokubambisana kunye antiplatelet kunye inhibitors uyakhetha of serotonin kwandisa umngcipheko ukopha LCD. Ngaphezu koko, akukho nako ukwandisa glycosides NSAID lwekhontenti plasma yegazi kunye, ngaloo ndlela, abangele exacerbation of ukusilela kwentliziyo congestive. "Ibuprom" ukwandisa impembelelo phezu anticoagulants emzimbeni womntu. Ngenxa yesi sizathu, kubalulekile ukubeka esweni parameters coagulation rhoqo, t. To. Ibuprofen kunciphisa kakhulu zegazi udibaniso.

Xa isicelo ukufana kunye iziyobisi lithium kunye "MTX" kakhulu ukwandisa umxholo ezi zinto kwi plasma yegazi. Ngokubambisana kunye cyclosporine nephrotoxicity kukhokelela ekwandeni le yokugqibela.

Indibaniso "Ibuproma" kunye amalungiselelo digitalis (digitalis) kunokubangela uphuhliso arrhythmias inhliziyo. Nonako ukuthatha eli NSAID ngokubambisana kunye acetylsalicylic acid (aspirin), ekubeni kukho ithuba ezimbi mpawu inzuzo esecaleni.

Iindibaniso quinolone arhente antibacterial, kunye nayiphi na NSAID (kwaye "Ibuproma" kuquka) kwandisa umngcipheko ukuxhuzula. Ukudibana ne amayeza, njengokuba "Zinovudin" kwandisa umngcipheko haemarthrosis kunye hematoma kwizigulane ezine-HIV.

Imibono ezigulane malunga namayeza

PVA Nonsteroidal - ezi amalungiselelo ezinzulu zidla uluhlu olubanzi yeziphumo. Ngoko ke, iimpendulo izigulane kwiindlela ezinjalo kusoloko kukho zombini kwicala akhabayo kunye navumelanayo. Ngaba Akukho ngaphandle kunye "Ibuprom".

Ubuninzi abantu bathabatha ichiza, wakholiswa ukusebenza kwakhe. Intlungu ngokukhawuleza azipheli yaye kangangexesha elide asibikho efana. Ichiza singqiniwe esexesheni buhlungu, intloko ebuhlungu kunye myositis, neuralgia kunye myalgia kwi.

Ngelo xesha, kukho izigulane awonwabanga impembelelo ichiza "Ibuprom". Imiyalelo itsho uphuhliso olukhawulezayo ukusebenza iintlungu, kodwa abathengi abaninzi baye bavakalelwa amanyathelo kweli chiza. Ukongezelela, abaninzi bakhalaza yokusabela ezingalunganga ezifana isicaphucaphu kunye yintloko.

Iqela elikhulu labantu ukhalazela ukuba "Ibuprom" singesuki lizinyo ngokupheleleyo. Nangona kule meko akukho mfuneko kuthi ukuba ichiza okubi. Inyaniso yokuba, umzekelo, xa pulpitis etsolo ayiyi kunceda nayiphi na ngaphandle inaliti ngqo gum ntlungu. Kwimeko apho lizinyo "Ibuprom" - lithuba ngokukhawuleza kangangoko kunokwenzeka ukuya kugqirha wamazinyo, ngaphandle abanengxaki ubuhlungu.

Enoba kwakuyintoni na, NSAIDs - oko obezvolivayuschie kunye isizukulwana esitsha arhente anti-ukudumba, olusebenzayo kuluhlu olubanzi kakhulu ezimbi. Nguwo lowo ngokoluvo uninzi kwabathengi kunye neengcali zezempilo.