'I-Dexamethasone' ijongana

"I-Dexamethasone" (amaconsi asehlohlo) anegama elichasene ne-antiergic, i-anti-inflammatory and anti-exsudative effect.

Amachiza asebenzisana neeprotein receptors ezithile zezicubu ezijoliswe kuyo kwaye ulawula ukuthetha kwii-genetic dependence genes. Ngaloo ndlela, le nkunkuma ifuthe iprotheni. "I-Dexamethasone" (amaconsi asehlohlo) anciphisa ukubunjwa, ukukhululwa kunye nomsebenzi wabamlamli abavuthayo (kuquka i-cinnam, i-histamine, i-enzymes i-lysosomal, i-prostaglandins).

Isilwanyana sinceda ukucima ukufuduka kweeseli ukuya kugxininiso lokuvuvukala, kuncitshiswe ukunyuka kwe-vascular in it, kunye ne-vasodilation. "I-Dexamethasone" (amaconsi asehlohlo) anefuthe elizinzileyo kwi-enzyme i-lysosomal kwiimbrane ze-leukocyte, ukuxinwa kwe-antibodies. Amachiza ayaphazamisa ukuqaphela i-antigen, inciphisa ukwakheka kwe-lipocortin, inefuthe eliphazamisayo ekukhululeni ukuvuvukala ngabalamli be-eosinophil. Oku kugxininisa iimbumba zeeseli zamathambo. Ezi miphumo zinceda ukunqanda iimpendulo ezivuzayo kwiimfucu ngokuphendula umonakalo wokuzivikela emzimbeni, umonakalo okanye umonakalo.

Ubungakanani befuthe elichasayo lonyango elithi "Dexamethasone" (amaconsi asehlohlo) emva kokulawulwa kwesinye isisombululo sisuka kwiiyure ezine ukuya kwezi-ezisibhozo.

Isilwanyana singena kakuhle kwi-conjunctiva kunye ne-epithelium ye-cornea. Emva kokulawulwa kwamanzi amaninzi ophthalmic, uxinzelelo lwengqondo lufezekiswa. Kwimiba yomonakalo okanye ukuvuvukala kwe-mucosa, ukwanda kwezinga lokungena (ukungena) kuphawulwe.

Isilwayo sithathwa kwindlela encinane. Phantse kwi-60-70% yonyango engena egazini kwenkqubo ebopha kwiiprotheni zeplasma.

I-metabolism yesilwanyana iqhutyelwa kwisibindi phantsi kweempembelelo ze-enzyme eziqukethe i-cytochrome. Ukuphulukiswa kweemetabolites kwenziwa ngeemfesi.

Amaconsi e-Dexamethasone akhonjisiwe ngenxa yokungahambanga nasiswini kunye ne-conjunctivitis, i-keratitis, i-keratoconjunctivitis, engahambisani nomonakalo we-epithelial, i-blepharitis, i-scleritis, i-episcleritis, i-uveitis, i-chorioretinitis, i-blefaconuncivitis. Amachiza anikwe i- neuritis ye-optic nerve, i- ophthalmia ebonisa uvelwano, kwaye njengonyango kunye nokuthintela ukuvuvukala kwixesha elilandelelanayo emva kwentshukumo.

Kubantu abadala abanokuvutha kwesimo esilunzima, irejista ye-dosing i-1-2 yehla ukusuka ezine ukuya kweyesihlandlo ngamahlanu ngeentsuku ezimbini, ngoko imyeza isetyenziswe 1-2 ihlahla ukuya kwi ezine ngosuku ngemini emine okanye ezintandathu.

Ubuninzi bexesha lokusetyenziswa kweziyobisi iiveki ezintandathu.

Kwizifo zamehlo ezilumkileyo, amayeza athatyathwa 1-2 ahla ephindwe kabini kwiintsuku ezimbini. Ukongezelela, isicatshulwa siphuqulwa ngaphandle kwexesha elinye okanye iiveki ezimbini.

Ukuthintela kunye nokunyangwa komonakalo we- eyeball emva kokuhlinzwa (i-antiglaucoma operation filtering) okanye i- eye dropping injured, "iDexamethasone" isetyenziswe ngosuku lotyando okanye ngosuku emva kokuhlinzwa.

Emva kokuphuma kwe-cataract, ukungenelela kwintsimbi yokubuyisela, kunye nangemva kokulimala, amayeza aqala ukusetyenziswa ukususela ngosuku lwesibhozo.

Ubuntwaneni (ukususela kwimithandathu ukuya kweyeshumi elinesibini) ekunyanga kweemeko ezivuthayo kunye neemeko, izidakamizwa zilawulwa ngokuchithwa ngamanzi ukuya kathathu ngosuku. Ubude bekhosi buvela kwiintsuku ezisixhenxe ukuya kwezilishumi. Ukuba kuyimfuneko, ukusetyenziswa kweyeza kunokuqhubeka emva kokuvavanywa kwe-fluorescein ngosuku lweshumi.

Njengoko uqeqesho lubonisa, le nkunkuma iyakunyamezela zizigulane, ngokubanzi, kakuhle. Nangona kunjalo, kwezinye iimeko, iziphumo ezibi zingenzeka. Ngoko ke, iilisi, ngokukodwa nge-cataracts, kufuneka zisetyenziswe phantsi kolawulo logqirha kwaye ziqwalasela ngokuthe ngqo imigaqo.