'Arimidex' - imiyalelo esetyenziswa kunye nengxelo

umhlaza webele yeyona ixhaphakileyo le ezininzi iintlobo yamathumba umhlaza kwisiqingatha ababhinqileyo yoluntu. Njengoko umthetho, esi sifo olufunyanwa elinye abafazi ezisithoba ngaphantsi kweminyaka minyaka imashumi mane anamihlanu, yaye zonke weshumi - eneminyaka engamashumi amahlanu anesihlanu.

Unyango nzima kukuba umhlaza kuye wonke umzimba ngokusebenzisa inkqubo emithanjeni yi ekumisweni Ukudlulela. Ekuchongeni sifo ngomhla wokuqala kunokwenzeka unyango omhle ukuze kuxolelwe.

Kodwa kwenzeka ukuba emva kokuba sicatshulwa kwezifundo ezininzi nechemotherapy, ukusetyenziswa elide amayeza ezihamba kukuba unyango okhethwe ngokuchanekileyo. uhlobo ngalunye lomhlaza iye iiprotokoli zalo unyango, ngokuxhomekeka kubudala, ngokunjalo phambili kwesifo.

Ukuze ubone indlela unyango baqhuba iimvavanyo, eyinhloko yayo cytology. Kuphela ke kunokwenzeka ukuba ufumane unyango olufanelekileyo. Enye yeengxaki abaphambili ukhetho iziyobisi na amathuba neziphumo ebezingalindelekanga kwi zangasese amalungu, amehlo, wesibindi nezintso, kwakunye awafuneki ithambo.

Efumanise imihlaza enama-oxhomekeke kukhokelela ekunyangeni abantu abamelene hormone, enye yazo 'Arimidex'.

into esebenzayo

A eminyaka embalwa edlulileyo, izigulane abafumene ukuqeshwa, waya ekhemesti kwaye ukuthenga okanye iyalele umhlalutyi zakhe ezinqwenelekayo iziyobisi. Ngaphandle umbuzo okanye zisola wasiwa unyango. Ekuhambeni kwexesha lethu, isigulane ufuna ukwazi oko uya kusela? Ziziphi iingxaki zempilo zifakelwayo kuvela?

Ukuze ngaphandle zonke iinkcaso, kufuneka ufunde imiyalelo ku 'Arimidex' umenzi. Le esisebenza beziyobisi - anastrozole. Lo arhente antineoplastic imvelaphi lwekhemikhali, uvimba imveliso ye aromatase enzyme.

Aromatase - into leyo ethatha inxaxheba inguqu ka emzimbeni sex oyindoda (androgens) kwabasetyhini (estrogen). Isixa-mali eyandisiweyo estrogen kukhuthaza ukukhula yamathumba abaxhomekeke estrogen.

Ukucinezela ukukhutshwa estrogen kunye anastrozole ezisetyenziswa idosi konwaywa 1 mg ngosuku. isigulana ngosuku lokuqala Ukuthatha ichiza ngokuqhubekayo, ukunciphisa ubungakanani hormone egazini kwi-70%, kwaye ngakumbi 84%.

isicelo

Ukuba isigulana okholose ngugqirha wakhe, yena uya ibhujiswe landela yonke imiyalelo kunye nezabelo. Enoba ke akusoloko ilungile. Wayenyangwa uninzi abemi - ifuthe lweziqalelo lwemitha kwi iiseli izifo. Noko ke, nokudla iziyobisi, xi ukukhula kwabo azipilisi - naye ichemotherapy.

Imiyalelo Amacwecwe 'Arimidex' abonisa ngokucacileyo ukuba zingasetyenziswa kuphela ukuba unyango eliqhelekileyo (common) umhlaza webele amabhinqa postmenopausal. Ithi isetyenziswe imveliso replacement for amanenekazi yabanjwa unyango "tamoxifen" ubuncinane iminyaka emithathu.

Ukongeza, izigulane abanikwe xa nisaqala somhlaza, ngokutsho imiyalelo ngokucacileyo, ncomo 'Arimidex' ufumana HIV kuphela.

balawule

Kuba transfer lula yeziphumo ebezingalindelekanga eli chiza ethile kufuneka siqwalasele ngenyameko indlela imicimbi yayo. Anastrazole ngendlela idosi encinane 1 mg isizathu akakwazi ukusabela namachiza okanye nezidlo, kwakunye kwehlisa ukusebenza namanye amalungu kunye neenkqubo.

Kulula ukunyanga kugaya, ukuthatha ipilisi, wahlamba phantsi namanzi amaninzi. ngenzuzo ngemihla kumele kwenzeke efanayo ixesha lokuba igazi lamanani ichiza ayawa.

Iziyobisi lalathelwe ekufumanekeni iiseli umhlaza, njengoko umthetho, asele iminyaka emibini ukuya emihlanu. Ugqirha abaya kufuneka atyikitye ishedyuli yeemvavanyo eziya kunceda esweni impilo jikelele kumguli kunye nomhlaza.

iimpawu

Baqhuba iminyaka emibini, izifundo laboratory zibonise ukuba anastrozole uyinxalenye 'Arimidex', zinokusetyenziswa kuphela xa abafazi postmenopausal. Oku kungenxa yokuba ukusetyenziswa ixesha elide nezinokubangela ubudlolo.

Izilwanyana ezisetyenziswa amalinge babonakala kweqanda ilahleko iqanda kunye nokunciphisa inani lokukhulelwa ekhuselekileyo. Inzalo abazalwa kunye abakhubazeke ngeendlela ezahlukeneyo.

Ukuthintela imibuzo ezahlukeneyo malunga ziziphumo ebezingalindelekanga, zonke iziphumo ziye yenziwe "Arimidex". Zonke iziphumo ebezingalindelekanga kwezinye iindawo ziye zachongwa kunye nokwanda okukhulu ngokwemithamo yemihla ngemihla yokwamkela (25 ukuya kuma-50 mg).

imiphumela emibi

Kule imiyalelo yosetyenziso "Armideksa" lidwelisa zonke i ukungaqheleki kunokwenzeka zaye eziqwalaselweyo amavolontiya ababhinqileyo ngexesha unyango. Xa abantu malunga amahlanu amawaka wathabatha inxaxheba kuphononongo, uninzi lwazo abaye baphathwa ngempumelelo.

• Kwakukho ukunyhashwa nervous system ngohlobo ixhala, ukudakumba, ukozela okanye sokulibala, utshintsho kwimo, ubuthathaka jikelele.
• nemithambo yegazi: uxinzelelo lwegazi oluphezulu, isiyezi, intloko ebuhlungu kakhulu, thrombosis, thrombophlebitis, leukopenia, nokudumba lohlobo inyama intliziyo.
• isixokelelwano sokuphefumla: ukuphefumla ume, izifo yokukrala kwemiphunga, empumlweni nasemqaleni (nephika, tracheobronchitis, laryngitis, rhinosinusitis, pharyngitis).
• GI: isicaphucaphu, ukugabha, umsebenzi kakuhle kwesisu (ukuqhina, isifo sorhudo), umlomo owomileyo, kwimvelaphi iingxaki amathumbu ukuba uneanorexia okanye ngokudla kunye iseti bubunzima engaphezulu.
• Ne G: kome kunye ukurhawuzelela of inwebu yangaphakathi, ukuphazamiseka zokuzala, zesibeleko ukopha ebangelwe lutshintsho beziyobisi.
• System Musculoskeletal: ukuxozwa kunokwenzeka esiqwini ithambo ngenxa ukusetyenziswa elide, undingqavulayo iminwe syndrome.

analogs

Iintsontelo ekhemisi akukho lula ukufumana iziyobisi ezithile ezifana. Kuba abo baye bafunda ngenyameko imiyalelo zokusetyenziswa 'Arimidex', analogs, obuphantsi kuye kwixabiso, kulula kakhulu ukufumana. Xa wayethetha xabiso liphantsi kakhulu akanyanzelekanga ukuba, ngenxa yokuba abo bachasene hormone, kodwa yayingumvelisi elungileyo, usoloko ibiza kakhulu.

analogs ezipheleleyo zokuYilwa kwe-arhente esebenzayo kufuneka kubandakanye anastrozole xa kukho umthamo 1 mg. Kumazwe zangaphambili ico ezinjalo kukho embalwa, kodwa ziveliswa kumazwe ahlukeneyo, amaxesha amaninzi oko ke aseBalti. Nangona kukho iziyobisi ezivelisa eIndiya, eRashiya, naseUkraine.

"Aksastrol"

Ichiza ivelisa mveliso zoxubo "Grindeks", Latvia. Ezingamashumi amabini anesibhozo ukuphakheja film tablets wawutyabeka nganye equlathe 1 mg of anastrozole.

Ubungqina bubonisa ukuba aphathwe umhlaza webele selekhulile abafazi postmenopausal.

Of Izimo - ukukhulelwa kunye zisanyisa, kwakunye uvakalelo ngamnye ukuya Anastrozole.

Ixabiso eli chiza ukuze avareji Russian yi 5-8 amawaka engange, yaye Ukraine - ukususela 1500 ukuya 1800 amawaka UAH.

"Anastera"

Amalungiselelo iqulethe 1 mg anastrozole, kodwa yavelisa eArgentina. Kukho iindidi ezimbini zokufaka: eyokuqala - namadyungudyungu ezimbini iipilisi elinesine nganye; yesibini - namadyungudyungu ezintathu iipilisi ezilishumi ngalinye.

iqela amayeza ichazwa njenge ochasene ihomoni, enzyme inhibitor.

Le zibonisa adweliswe ukongeza uhlobo estrogenpozitivnogo unyango lomhlaza amabhinqa postmenopausal ithuba ukusebenzisa izigulane uhlobo estrogenotritsatelnym, kodwa amava esihle unyango "Tamoxifen" ababekade.

"Anastrozole Sandoz"

Iveliswe e Germany yenkampani eyenza "Sandoz". Umqulu blister, amacwecwe amabini anamanci mabini anesibhozo. indlela esithathwa ukufumana ngokupheleleyo ungqamane umyalelo 'Arimidex'.

I contra-kubonisiwe, wamitha, lokuncancisa kunye nabantwana.

Iindleko ichiza usezantsi kakhulu ngaphezu yokuqala. Kwakhona ukunyamezeleka kakuhle, kodwa ekhoyo ngakumbi ukuthenga.

Izimo

Njengoko kukhankanyiwe ngasentla, bephethwe Arimidex 'imiyalelo ayikwazi ukuba isetyenziswe abasetyhini ngexesha lokukhulelwa kunye zisanyisa.

Omnye wemiba echaphazela ukukwazi ukusebenzisa ichiza, lo ngowona tolerability ngamnye. Ingakumbi ukuba ubuntununtunu Anastrozole, yaye bahlala primenopauze nokusebenzisa "Tamoxifen" okanye iziyobisi estrogen 'Arimidex' ayinakusetyenziswa.

Ngenyameko, okanye ingasetyenziswa emane abantu abaphethwe kwamathambo, kunciphise balance lipid, isifo sentliziyo.

Abafazi abaphethwe kwamathambo, notyekelo ukuthambisa kunye ubu kwamathambo umenzi imiyalelo 'Arimidex' kuchazwe ngokucacileyo ukuba ukusetyenziswa kunokwenzeka, kodwa ngononophelo olukhulu. Kuyimfuneko ukuba ivavanywe ukuqinisekisa kwamathambo, kwakunye oyifunayo kufakelelwa calcium ezongezelelweyo kunye novithamini D. Kwiimeko ezikhethekileyo, xa kukho amathuba aphezulu ukuncipha mninzi unakho ekuqhubeni bisphosphonates eqongeni ezisaqalayo zomhlaza phambi sabele 'Arimidex'.

kwezinye iindawo

abawathandayo Great hormone iintlobo ezahlukeneyo abadlali. Le midlalo in abanxibe impahla kunye powerlifting. Phambi kokuba khuphiswano lakudlula ikhosi eyodwa steroid, ebavumela ukuba bafumane imilo ngokupheleleyo emzimbeni.

Ukuba uyakhumbula, ekusetyenzisweni imiyalelo 'Arimidex', analogue yayo esetyenziswa ukucinezela iihomoni ababhinqileyo ababandakanyekayo ukuyilwa iimpawu sex ephambili. Ngexesha iimbaleki therapy steroid bajamelana namadlala adumbileyo mammary, bomzimba, ukuba bomvu.

Ukongeza ezizodwa iimbaleki iimpahla badla ukusebenzisa analogue 'Arimidex', ngokulandela yonke imiyalelo idosi ixesha lokusetyenziswa.

Ukuze aphephe zonke "ngamakhubalo" le unyango ekhethiweyo, iimbaleki uqale ukuthatha Anastrazole ngosuku lweshumi ukususela ekuqaleni kwekhosi bystrovyvodimymi steroids. Nangona le ndlela ayikho into ilikhubalo yaye kufuneka kwenziwe phantsi kweliso elibukhali likagqirha olungqongqo.

reviews

iziyobisi kwamadlala - elininzi ntshikilelo umzimba. Luchaphazela onke amalungu kunye neenkqubo, kwaye umzimba akazamkeli izinto eziyimfuneko, uzama ukubuyisela kuba ngeendlela ezahlukeneyo.

Izimvo oogqirha nezigulane ejongene 'Arimidex' iziyobisi, kunokuba antsonkothileyo. Inani elikhulu lezigulane wafumana ukuqeshwa "Arimidex 'emva kwenye ochasene estrogen unyango -" tamoxifen ".

Kwindawo yokuqala iindleko eziphezulu beziyobisi uyalandelwa. Ukwenza nokuqeshwa, iingcali ezininzi bacebisa ukuba ufunde imiyalelo zokusetyenziswa 'Arimidex', analogs kunye nohlolo sele isicelo abantu bakhe. Kutheni na ukuze imibuzo?

yokungenisa umenzi iziyobisi, ngenxa izigulane ezinomhlaza, kokuba ikhutshwe simahla. Ukuze uyifumane, kufuneka ngamawaka osibhozo engange ngenyanga. Ayizizo zonke isigulane ukusithenga.

Kodwa nokubuyekezwa izigulane opt nje anastrozole into esebenzayo, ezintle kuphela. athwala Lowo ngendlela elula kakhulu kunento "Tamoxifen". Ngaphantsi yityhefu emzimbeni, kwaye okona kubaluleke kakhulu, yenza akukho iziphumo ebezingalindelekanga enjalo.

Kwiinyanga zokuqala of the reception, kuxhomekeka ngamnye ukunyamezelana 'Arimidex' anganika isicaphucaphu, ukugabha kunye ubuthathaka jikelele. Abo ibanjelwe ngexesha ichemotherapy akazange athi ngokuqinisekileyo ukuba wanikwa le status.

Ngokubanzi, ukuthatha iipilisi ndawo eqhelekileyo. Izigulane awayezama uthenge zasekhaya kwaye ugcine amalungiselelo ngobuncwane efanayo esebenzayo, abonelisekanga. Wasivumela kubi kakhulu, kwaye okona kubaluleke kakhulu, umqondiso yokuqala yaba buhlungu kakhulu kwamalunga.

Drug yokuzikhethela?

Kukho ingxaki enkulu ekufumaneni unyango simahla abafazi babona ukuba une - "umhlaza webele". Free kwiziyobisi izigulane Oncology Centre thembela kuphela "Tamoxifen", kodwa abalimi zasekhaya.

Le ukulungiselela abathwele nzima, nangona iziphumo unika okulungileyo. Ngenxa kwayo ekusetyenzisweni imiyalelo 'Arimidex', analogue zayo, ungakwazi isigqibo amachiza kufuneka yamkelwe.

Oogqirha bathi elona xesha lifanelekileyo unyango "Arimidex" - kwisithuba seminyaka emithathu okanye emine emva kokuqalisa unyango "tamoxifen". kunqabile kakhulu, oko kunokubonwa njenge ukulungiselela unyango lokuqala.

Qesha abafazi ukuba anastrozole ngenxa zezempilo, lo gama abanye, transcriptase ndlongondlongo ngakumbi bachasene sigulane asikwazi kushukuma. Kodwa bona i umbuzo evulekileyo malunga nokufumaneka ichiza. iziyobisi Iipakethe ezixabisa ngaphezu elizifumeneyo umhlala-phantsi. A macwecwe mabini anesibhozo pack endaweni amathathu nganye yonyaka zidibanisa iindleko ezongezelelweyo.

Ukuze isigqibo ngokuthatha lo amayeza, kufuneka uqiniseke ukuba funda inkcazo 'Arimidex' kwi imiyalelo kunye nohlaziyo sele kudlule ikhondo kwizigulane. Mhlawumbi baya kukunceda nesigqibo: ukuthatha okanye hayi. Ngoxa ukuthetha amachiza asetyenziswa nomhlaza webele njengoko ichiza oyikhethileyo engalunganga.

Ngalinye abafazi beva uxilongo eyoyikekayo, ukulwa ubomi bakhe nempilo wokugqibela, besebenzisa zonke iindlela.