Yintoni isifo Addison kaThixo?

isifo Addison lenzeka xa ukungasebenzi le uthinte adrenal. Esi sifo olufunyanwa amadoda kunye nabafazi, uninzi (engama-30 ukuya kuma-40) eliqina. Sisifo inqabile, nto leyo ebhaliswe umntu ngamnye 100 lamawaka. Population. isifo Addison Biermer ukuze aphuhlise ngenxa yeenkqubo samathambo, izifo ezosulelayo (negcushuwa, isifo sephepha kunye adrenals icesina), kwaye amyloidosis kunye nangezilonda amabi. Ngowe-70% yezigulane, esi sifo kwenzeka ngenxa yokuba ukuphazamiseka amajoni omzimba (izilwa aqalile ukuthatha iiseli zomzimba namaqumrhu angaphandle, ahlasele uze ubatshabalalise.) Ngokutshatyalaliswa iiseli neuron adrenal kunciphisa njini gluco kunye mineralocorticoids (cortisol, 11-deoxycorticosterone, aldosterone). Izazinzulu lubonise ukuba glucocorticoids elawula iinkqubo ezahlukeneyo kwemichiza emzimbeni (olawula uxinzelelo lwegazi, insulin yoxinaniso, ebandakanyekileyo ekumiseleni protein yokuqaphela, lipids kunye carbohydrate).

Gipokortitsizm sivame ukuba izigulane kunye hormone le uthinte adrenal. Kwiimeko ezininzi, umyalezo esi sifo nangoku uhlala ayaziwa. insufficiency adrenal ihlelwa eziziprayimari nezizisekondari. ukusilela Primary senzeka ngokoyiswa izihlunu adrenal, kwaye secondary - ngenxa inkanuko elingonelanga hormone adrenocorticotropic.

Isifo Iimpawu Addison kaThixo

Iimpawu kwezonyango sisifo esibangelwa ukuhluleka an kwezimbiwa inyama kunye glucocorticoids. Ezona mpawu kakhulu iimpawu zezi ubuthathaka, hypotension, emathunjini kukuba iveza (isicaphucaphu, ukungabi namdla, ukugabha, ukuqhina, isisu rhoqo indawo). Ezinye hypochlorhydria izigulane.

isifo Addison kaThixo lukhatshwa ucaphuka ukwanda okanye mood udandathekile, intloko ebuhlungu rhoqo kunye ugwayi. X-reyi yesifuba ibonisa ukuhla ubukhulu entliziyweni. Le electrocardiogram amarekhodi iimpawu hyperkalemia (high potassium yoxinaniso egazini). Ulusu nombala akabi kunjalo ibonisa ubungqongqo esi sifo,, ukwanda okanye unciphise kwi yonyango ubungqina ukusebenza isenzo zonyango.

isifo Addison bukaThixo luphawulwa imvelaphi iimpawu zasesekondari kangako kakhulu. Kakhulu neze sifo kubonakala ngaphandle nombala (ngoko ke isihloko "white Addison"). Esona sizathu sokuba esi sifo adrenals isifo sephepha. Xa engekho unyango olufanelekileyo sifo Addison kaThixo esintsonkothileyo. Iimpawu Clinical ziyanyuswa: isicaphucaphu, ukugabha, urhudo, uxinzelelo lwegazi ashiye kabukhali, ukwandisa uyondelelwano lwee- potassium egazini. Egazini engabalulekanga nitrogen intsalela kwandisa inani iiseli ezibomvu, mpilo. Ngoko ke, ukuba ngexesha lobunzima addisonicheskogo nomonde akuthethi ukunika uncedo ngexesha, safa kunye iimpawu kwezintso kunye nesifo sentliziyo.

Imida laboratory sibalulekileyo uphethwe okuqulethwe 17-OCS in plasma ze-KS 17 umchamo, kwakunye nokuhla kwamazinga iswekile egazini. iimviwo Morphological yegazi ibonisa lymphocytosis, eosinophilia kunye ESR libaziseko.

isifo Addison bukaThixo umahluko ukusuka zifo ezilandelayo: isifo seswekile lobhedu, pellagra, netyhefu arsenite kunye Bismut Argentum. Isifo idla ikhondo ezingapheliyo kunye soveliso ezithile. Addison Biermer elihlabayo sifo emiselwe ubungqongqo imiqondiso emikhulu zesi sifo, kwakunye ngenani iziyobisi eziyimfuneko ukuvala insufficiency adrenal.