Umqobo igazi-nobuchopho

Okwangoku, kukho inani elikhulu zonke izitshanguba-luvo ye umntu iba kukwenzakala abangene. Kwaye nje inxalenye encinane ezitshangubeni kubangela ngqo izifo central system luvo.

Ngenxa ezinye iimpawu zayo nervous system umdla kakhulu ukusuka kwindawo umbono zenzululwazi. Eyona nto kukuba kwendlela ezakhiwe ngayo inkqubo luvo unzima kakhulu ukuqonda. Zenza liqine isiseko-luvo banezimvo zabo, yahlukile kwezinye izicwili zomntu, isakhiwo.

Enye yezona iinkalo ziphambili zobuchopho kukuba sezantsi kakhulu ukuntshula. Oku akuthethi ukuba luvo ezimashakeleyo musa ukuntshula, kodwa lokuhlangulwa kade kakhulu kwaye ifuna iimeko ezithile.

Enye inkalo e-nervous system ngokubanzi, ingakumbi CNS na umqobo igazi-ingqondo (bbb).

Ngoko ke akukho mfihlakalo ukuba ingqondo kunye umnqonqo ngqo ulwelo ezifanayo kumafa ukuya saline komzimba, kodwa iyahluka ukusuka umxholo amaqhezu ezahlukeneyo iiprothini kunye Izakha. Cerebrospinal (okanye cerebrospinal) ulwelo luqokelelane egazini kunye nkovu phantsi "filter" ezizodwa, apho wenza indima njengomqobo segazi lobuchopho.

iiseli Special nabo mezhendotelialnymi kuthintela kwii- iiseli zegazi kulwelo. Namhlanje, izazinzulu khange ndicinge ngokupheleleyo indlela ukulawulwa uyakwazi ukuhluza isithintelo, kodwa kwakusazeka ukuba amandla amandla ayo ukutshintsha ngomsebenzi pathways ingqondo. Ukongeza, umqobo igazi-kobuchopho umahluko kwiingingqi ezahlukeneyo zobuchopho, nto leyo ebangela ukuba ezahlukahlukeneyo nesikhundla sayo ulwelo ukuhluza (igazi kunye nkovu).

Uphononongo lubonise ukuba ezinye izinto kusichukumisa BBB lusa lwa imithambo yegazi, enye inxalenye yawo - ukuba iimpahla ezo emithanjeni nkqubo, kwaye abanye bavela zosasazo ezimbini ngesantya esifanayo. En, kunye nenkqubo ekhethekileyo ukuzibamba unexplored de ukwakhiwa inikeza unikezelo kwezinto kulwelo lwe- cerebrospinal kwi isixa-mali kuyimfuneko kwinkqubo luvo. Oku kwenzeka kunye nokulawulwa umthamo wesahlulo engamanzi, imali kunye nokwakhiwa iiproteins, kwakunye nokwakhiwa kwe ion (le yokugqibela simelwe potassium kunye sodium).

Kutheni sifuna umqobo igazi-ingqondo?

Ubukhulu becala wesenzo mayibhekiswe imeko ezisemajukujukwini ngokumalunga nenkqubo luvo, kodwa ezisebenza umsebenzi yokhuselo, ukuvimbela umthondo kungena iintsholongwane CSF kunye iintsholongwane ukususela kumsinga igazi okanye nkovu. Kubalulekile ukuqonda ukuba xa kuthe yezitenxo ekusebenzeni imiphumo BBB iya kuba kubi kakhulu. Ngenxa yoko, iintsholongwane eyangena cerebrospinal kukhokelela fluid meningitis, kobuchopho kunye nezinye ukudumba meninges nezihlunu ebuchotsheni.

izifundo ezininzi olwenziwa ngabasebenzi, kwenza ukuba kungenzeka ukuba nefuthe bandwidth ye njengomqobo ingqondo igazi amalungiselelo ezahlukeneyo. Ngaphandle koko, ngamayeza asetyenziswa ukuchonga ngaphambili liqalisile ngalo msebenzi. Namhlanje, oogqirha zaziwa kakuhle oko iziyobisi kunye nendlela echaphazela BBB. Ngaphezu koko, siye safunda ukuba basebenzise ezi propati ukuze kuzuze yomntu.

Ngoko ke, lo umqobo igazi-kobuchopho iqela imisebenzi ebalulekileyo kakhulu ezixhasa imeko ngokupheleleyo amalungu angaphakathi chelvoechesokgo yomzimba. Noko ke, kufuneka kuqondwe ukuba iimpawu ezinjalo njengomqobo kwenza kube ethe kakhulu zombini ukonzakala kunye neemeko ezahlukeneyo lwezidumbu, yiyo ke le nto kubaluleke kangaka ukuqonda ingqalelo le miba kwi nokuthintela kunye nokunyanga izifo.