Phathogenicity kunye virulence ezincinane. Virulence - it ...

Umzimba womntu likhaya iintsholongwane malunga 100 trillionov. Izazinzulu banamhlanje kuphela ngoku uyazi kakuhle indlela ezi uluntu ezintsonkothileyo basebenzisane mntu. Bona kuchaphazela inkqubo ukwetyisa, amajoni omzimba ekusenokwenzeka kwimpilo-ntle engqondweni. Noko ke, asingabo bonke ntsholongwane yokuhlalisana kunye umzimba womntu ngoxolo nangemvisiswano. Ibizwa silwanyana yayintsholongwane eyosulela ezinokubangela izifo izityalo, izilwanyana okanye izinambuzane. Amagciwane baveze phathogenicity lwabo besebenzisa virulence. Ngoko ke, yintoni na virulence?

Ingcamango virulence

Virulence - siphelise ukuchaza iqondo phathogenicity ngayo intsholongwane. Ngoko ke, lo njengabamisi virulence ye gciwane naziphi na iimpawu zayo yemfuza, kwemichiza okanye beemeko ukuvumela ezibangela izifo.

Ubudlelwane phakathi komkhosi kunye pathogen zisoloko onamandla, ngenxa yokuba ngamnye uyakwazi ukutshintsha umsebenzi kunye nemisebenzi enye. Isiphumo ukuzalana ixhomekeke virulence ka pathogen kunye iqondo ekhoyo ukumelana okanye susceptibility yomkhosi. Indima ebalulekileyo kwakhona wadlala ukusebenza kweendlela zokuzikhusela kumzimba.

imiba Virulence olunxulumene ngqo iipropati ezivumela iintsholongwane eziyingozi ukungena okanye emzimbeni-mkhosi kunye ezidala izifo. Ezi ziquka ityhefu iintsholongwane ezinegalelo phathogenicity.

izinto ezibalulekileyo

Invasiveness - oku langaphakathi esikule. Oku kuquka iindlela amakoloni kunokwenzeka nokuveliswa kwezinto extracellular enegalelo ithuba lokuhlasela kwaye kuthintelwe okanye ukoyisa iindlela ezithile zokhuselo.

Toksogennost - ukukwazi zigutyula abulale. Iintsholongwane ukuvelisa iindidi ezimbini ityhefu: endotoxins kunye exotoxins. Exotoxins wakhululwa iiseli bacteria nokukhuthaza ukukhula iintsholongwane. Endotoxins kukho into cell.

ubuthi bacteria, zombini enyibilikayo kunye iseli-ezinxulumene, ube nokuhanjiswa yi igazi nkovu inyama kwaye ibangele neziphumo cytotoxic kwiindawo ezikude ukusuka kwindawo sokuqala sokungena. ityhefu ethile bacteria nabo ukudala amathanga ukuba bathathe inxaxheba kule hlaselo.

Phathogenicity kunye virulence ezincinane

Phathogenicity - ukukwazi ephilayo okubangela izifo. Leli khono ufuzo le pathogen, leyo Ayize nakanye kwicala host. Kuba ngamagciwane olungenelelayo, le ukukwazi ukuba isifo ayikho isegazini. Adala ngayo ukubiza uluhlu olubanzi virulence.

Virulence - ingqiqo ethetha into kuhlangene nengqiqo phathogenicity. The degree of virulence ka pathogen lidla ngamazinga bakwazi ukwenza umkhosi kwaye zizakuxhomekeka izinto ezithile. izinto virulence negalelo phathogenicity, okt ukunceda okubangela izifo.

kwamagciwane

Abaninzi baye ngokuphindaphindiweyo ingqalelo kwizibhengezo ezahlukeneyo mhlomlo imveliso ukuba babanga ukuba bambulale 99% zeentsholongwane. Lwegciwane - eli gama lisetyenziswa ukuchaza izinto eziphilayo ezincinane (kwiintsholongwane), ebangela izifo ezahlukahlukeneyo. In isigama eziphilayo, akwabizwa ngokuba arhente causative. Kukho iindidi eziliqela iintsholongwane ezibangela izifo ezahlukahlukeneyo ukususela umhlaza umkhuhlane kunye nesiphelo.

amagciwane izifo zichaphazela umntu ngeendlela ezininzi, kuxhomekeke virulence lwabo. Virulence - eli gama lisetyenziswa ukuchaza impumelelo lwegciwane ethile. Le pathogen ngokunamandla ngakumbi kuye, kokukhona kuya kuba nefuthe elibi kakhulu kwimpilo yabantu.

Yezizathu virulence

imiba Virulence namanqaku kwamagciwane ngawaphi anazo lwegciwane virulence. Okukhona, kokukhona kubonakala ukuba kuya kuba unobangela sifo. Ezi zinto kunika i inzuzo zokujongana kumajoni omzimba womntu, kwaye ngakumbi, abulalayo kokukhona ingaba.

Kukho iintlobo ezininzi ezahlukeneyo izinto virulence ukuze abe nokuba sikude kwi lwegciwane ethile: izinto kwamathanga, enterotoxins kunye hemolysin. Virulence - yinto phawu oluninzi, emele iqondo sisifo esibangelwa silwanyana. Lo msebenzi, nto leyo ubonisa intsebenziswano phakathi pathogen kunye othwala. Virulence lidla ngamazinga kunye ekukwazini pathogen ukwanda. Oku kwakhona ixhomekeke othwala neemeko zokusingqongileyo.

A pathogen bacteria ngokuqhelekileyo kuchazwa nawuphi na igciwane egu- ebangela izifo. ikhono layo okubangela izifo kuthiwa kwamagciwane. Le virulence le silwanyana ixhomekeke ngqo kwi kuhlobo usulelo kwaye sisalathisi ebukhulwini isifo ezisibangwayo.