Izidumbu Ketone Umchamo - izinto kunokwenzeka

imizimba Ketone - a imveliso ekhethekileyo pathways abunjwe esibindini. Zibizwa ngokuba imizimba acetone. Ezi ziquka: acetoacetic, beta-hydroxybutyric acid, acetone. Ezi izinto kufuneka isakhiwo imichiza efanayo yaye babe interconversion kwipropati. Yolungelelwaniso imizimba ketone esibindini ixhomekeke ngqo kumandla njani yaye kuphazamiseka kakhulu ngenxa yokusilela metabolic. Kwasekwa kwesibindi, bephuma egazini ancedisana amasebe awohlukeneyo, apho inxaxheba kumjikelo ka-asidi tricarboxylic ukubola emanzini kunye carbon dioxide. Amatyala ukuba imizimba ketone in nomchamo. Izizathu zale meko, kwakunye amaxabiso esinokubakho ngenxa yesi uphawu kuxoxwa ngezantsi.

Njengoko sele kukhankanyiwe, Ketova umzimba kunye yangoku kunikelwa ngalo igazi kwesibindi ukuya kwamanye amalungu. Ngenxa agqithisile egazini, ahluka nge uphefumla (kunokwenzeka nkqu "acetone" ivumba ngexesha umoya nomphunga) kunye nenkqubo excretory. Ngamanye amazwi, kukho imizimba ketone Umchamo. Kodwa izizathu ukuba ziveliswa kwemfuneko, inokuba nomahluko.

Yolungelelwaniso lwemizimba ketone yandiswa ngexesha ukutya, isondlo bezuglevodistom rhoqo, ukutya izixa ezikhulu iimveliso protein, ketoacidosis utywala, ku ri na ityuwa metal kwealkali (nawaphula umjikelo tricarbonyl) ezisetyenziswa kwiimveliso ukutya ekuthiwa-acid ketogenic. Yi amino ketogenic acid ziquka phenylalanine, tyrosine, isoleucine, leucine.

Noko ke, hayi kuphela ukudla ezithile igalelo kwisizukulwana awongezelelekileyo kwemizimba ketone, kuba yintoni kuba imizimba ketone Umchamo, isizathu nayo kutyando, ukukhulelwa, ntshikilelo ebalulekileyo emzimbeni, imveliso insulin asanelanga. Iyafuna ukunikela ingqalelo unobangela yokugqibela kunokwenzeka. Kuye kwaphawulwa ukuba ukuyilwa imizimba ketone ngokomthamo ingakumbi enkulu - ekuthiwa-giperketonemiya - kwenzeka xa isiqaqa abaneswekile.

Phambi imizimba ketone Umchamo ngentla eqhelekileyo, umchamo lithi libe livumba ethile "elinuka". Umzekelo, isifo seswekile umchamo kwi ivumba layo ukuze bufane apile ebolileyo. Kufuneka abe khona lokugcina imizimba ketone kwi umchamo, izinga lwabo - 20-50 mg / ngosuku. Ukuba imizimba ketone kwi umchamo lingaphaya eqhelekileyo, oko kusenokuba kubonisa iinkqubo zophendlo lwezifo emzimbeni. Inani elikhulu kwezi zinto kwi umchamo kuthiwa ketonuria.

Ngokusekelwe ulwazi ngentla ezingenisiweyo, kuyimfuneko ukuba anikele ingqalelo ekhethekileyo isiqulatho aphezulu olawulo ketone in nomchamo. ketonuria Isizathu kunokuba kakhulu engeyongozi, non-umonzakalo emzimbeni. Abantwana abancinane aninakwenza nto ukuthetha kwemizimba ketone in nomchamo. UNorma neentsana zabo, ukuze kugqithiswa, nkqu utshintsho ezincinane ekutyeni, ngokweemvakalelo amava nokudinwa. Noko ke, unobangela imizimba ketone kwi umchamo inokuba lwezidumbu - umz, isifo seswekile, umkhuhlane, ifiva nebomvu, segazi, pancreatitis etsolo, ifiva, ianemia, chaza predkomatoznye, izifo ezosulelayo kunye izifo zengqondo kunye nezinye izifo ezininzi. Ngaphandle ngale mithetho ilapha ngasentla ebangela elingaphaya imizimba ketone Umchamo, ingaba isifo enqabileyo naso ezifana nesifo maple isiraphu umchamo.

Xa sokwezela uvavanyo ubukho ketones, isigulana ufumana isiphumo esibi, ukuba imizimba ketone kwi umchamo ayidluli lo mmiselo, kwaye elihle ukuba umchamo engaphezulu kwe kuyimfuneko. Inani "uphawu lokudibanisa" kwi ngesiphumo lokuvandlakanya ukubonisa iqondo ketonuria. Umzekelo, i "umnqamlezo" - nguvumazonke indlela HIV, ezine - leyo basabela kukubi ukuba ngokuqinisekileyo ibonisa ubukho sisifo esibi.

Iziphumo zohlalutyo kwi ketonuria inokungabonisi ngokucacileyo isifo umguli. Nditsho ubukho liphezulu imizimba ketone kwi umchamo ayisoloko ibonisa ukuba kukho ingxaki enkulu kwimpilo. Kodwa ke, ukuze babe inkomba kokuphonononga esi imeko jikelele.