Ipilisi ukuze amaqhakuva phezu kobuso, "Roaccutane": ncomo, iifoto ngaphambi nasemva uqeqesho

Wonke elivisayo xa ufikisa ujongene nengxaki induna okanye mpawu ngokwenzululwazi induna. Umntu unako lula kunceda iinkqubo izithambiso kunye nesenzo okungqalileyo. Abantu zonke ezi zazo imeko yesikhumba akukho ngcono. iziphene izithambiso ngohlobo blackheads, namaqhakuva yako kubo iqhubeka kakuhle mdala. Kulo mzekelo, umntu uba nje emzimbeni, kodwa kananjalo ubuhlungu obukhulu ngokweemvakalelo. Iingxaki ndawonye nesikhumba ukuphazamisa bazive bezithembile kwaye ukonwabele ngokupheleleyo ubomi. Kwiimeko apho zonke ezinye iindlela zolawulo zibonisa ngamampunge zabo, oogqirha amisele ichiza kwizigulane "Roaccutane". Ukuphononongwa, iifoto ngaphambi kunye nasemva unyango kunye ezi pilisi kukhokelela kwisigqibo ucikizeko zazo eziphakamileyo. Nangona kunjalo, kubalulekile ukukhumbula ukuba inani elikhulu yeziphumo ebezingalindelekanga kunye imfuneko yokuba kubekwe iliso elibukhali ngamaxesha hormone parameters yegazi yesigulane.

"Roaccutane" efunyenwe reviews ezintle oogqirha. Iingcali zithi: kungekho Izimo, kwakunye ngokuthobela ngokupheleleyo nazo zonke izindululo isigulane onesiphumo elihle zonyango kunye izithambiso.

Yintoni na le yeza?

"Roaccutane" - ncomo tablet leyo ndlela ikakhulu HIV - yinto ekulungiseleleni unyango ngqo induna kunye blackheads. Ezi njengezingxobo ziqulathe ebomvu nombala kumiswa, ingxenye enkulu leyo isotretinoin kwi-mali ka-10 mg okanye 20 mg (kuxhomekeke iifom ukukhululwa). Ukongeza kule ukulungiselela retinoid iquka ezongezelelweyo amacandelo, phakathi apho zesoya oyile, fini, glycerol, gelatin, itapile starch kunye nedayi ezahlukeneyo umgangatho ukutya. "Roaccutane" Libonisa ukuba unyango iifom kakhulu induna ukuba asinyangeki ngeendlela eziqhelekileyo.

Njengoko imisebenzi iziyobisi?

Interesting nto: oogqirha nangoku khange ndicinge phandle indlela ngqo amanyathelo "Roaccutane" iziyobisi. Ukuphononongwa, iifoto ngaphambi kunye nasemva unyango kunye nale arhente ikhuthaze oogqirha abaninzi bancoma ukuba izigulane zabo onepateni nzima induna. Isotretinoin, nto leyo ke stereoisomer kwelentshona ye-retinoic acid, abe neziphumo zilandelayo emzimbeni womntu:

• ezilawulayo umsebenzi ngokugqithisileyo amadlala sebaceous.

• Ukuncipha ubukhulu.

• Ingaba i isiphumo anti-ukudumba apha esikhumbeni.

Kutheni induna kwakhiwa?

Le epithelium ogubungele bulb iinwele, kukhuliswe exfoliated. Iiseli oko corneocytes, natywinwa umhlaza obucala ngekeratini kunye sebum. Oku kukhokelela ukuyilwa comedones, ilandelwe yi-kuthinjwe impendulo arhabaxa. Sebum kokona kutya ukukhula eliphakathi kwaye kuveliswe uhlobo Propionibacterium acnes iintsholongwane. Bona ezona zinto zifuneka kuqala ezingundoqo ukuvela amabala ezininzi, ububomvu kunye nezinye iziganeko ezingemnandi iqhotyoshelweyo.

Drug "Roaccutane" kwakhona ukuba oogqirha ubungqina, dermatologically kuqinisekiswa ukukwazi layo ukucinezela kunyebeleziso sebocytes. It ibuyisela izinga physiologically eqhelekileyo umahluko kweeseli epithelial. "Roaccutane" kunciphisa umsebenzi sebum yaye ukukhula kwamagciwane iyakuvingca, kukukrala isusiwe, umphumo elungileyo izithambiso kuyaphunyezwa.

Ziziphi pharmacokinetics kweli chiza?

Isotretinoin ifunxwe ukusuka iphecana emathunjini, kwaye xi ubuninzi ibanjiwe egazini kwiiyure 2-4 emva nolawulo. Kukho ezinye iinkalo ukusetyenziswa "Roaccutane" iziyobisi. Ukuphonononga kuvumela iingcali ukuze enze isigqibo ilandelayo: tablet ingcono asele emva kwesidlo. Oku kwandisa bioavailability of isotretinoin ngamaxesha 2 kuthelekiswa ne yokwamkela imithi ungatyanga.

Eyona nto iphambili esebenzayo i lubopha olugqityiweyo kwiiproteni igazi umzimba ukwenza iimveliso ezine eziphambili. isotretinoin wabonisa metabolites wayo umchamo endleni kwisithuba seeyure 19 ukuya 29. Ukubuyiselwa isiqulatho komzimba of retinoids ebantwini kwenzeka emva kweeveki-2 ekupheleni kwekhosi imithi.

Ziziphi ithamo ukuthatha iyeza?

Malunga koko, kangakanani ukuba 'Roaccutane "(tablets), uyakwazi ukuva ngeempendulo ezahlukeneyo. Kufuneka kuqatshelwe kanjalo ukuba esi njengenqobo elibekwe kuphela igqirha khona ngokusekelwe kwiimeko ngamnye imeko yesigulane.

Le medicament "Roaccutane" ratings, ifoto ngaphambi nasemva unyango, eyaqinisekisa ukusebenza kwayo phezulu, ngokuqhelekileyo ethathwa kanye okanye kabini ngemini ngomlomo.

Ukubakho Dynamics unyango, kunye neziphumo ebezingalindelekanga kuxhomekeke isimo sokuqala kumguli idosi echongiweyo. Ezi iimeko ziyalela indlela ngamnye ukuba ukumisela indlela ichiza "Roaccutane". Ukuphonononga amagqirha lubonisa ukuba ukuqala usoloko kakuhle idosi isezantsi ebalwa olinganise 0.5 mg isotretinoin nganye 1 kg ubunzima bomzimba sesigulane iiyure ezingama-24. Ngokutsho manani, umlinganiselo inani prescribers - 0.5-1.0 mg / ubunzima bomzimba kg ngosuku. Ukuba iqondo induna xa isigulane kwachazwa ngokuthi nzima, ngoko ke unikwe idosi enkulu - to 2.0 mg / kg ngosuku. Ngaphezu koko, kwezi meko eziqala imali encinci - 10 mg / imini, ukuba kufanelekile, banda 1 mg / ubunzima bomzimba kg nganye iiyure ezingama-24.

Kukho kwirejimeni "Roaccutane" kangangoko amayeza induna. Ukuphonononga amagqirha ubonise isixa iziyobisi 120-150 mg / ubunzima bomzimba kg, isasazwa kwi kwikhosi yonke. Ngoko ke, ubude unyango kuxhomekeke idosi ekujongwe yemihla ngemihla amayeza. Ngokwesiqhelo isithuba kwiiveki 16-24 kunokwenzeka ukufezekisa umfanekiso phantse ngokupheleleyo kuxolelwe induna. Ukuba isigulane ethwele scheme ukwamkelwa embi ezinyuliweyo, idosi yemihla ngemihla waba uyancipha kwaye yandisa ixesha unyango.

Ngokusisiseko, indlela enye unyango "Roaccutane" iziyobisi - ncomo, iifoto ngaphambi nasemva uqinisekise le nto - ngokwaneleyo ngenxa yokuduka epheleleyo induna. Nakuba kunjalo, ukuba ngaba isigulane unalo ndiphinde ecacileyo, ugqirha ukuze amisele ixesha lesibini nezinyangayo. Kulo mzekelo, umthamo kunye nexesha unyango kunye beziyobisi kuhlala ingatshintshanga.

Ixesha isiphumo izithambiso, nebonelela iipilisi induna ebusweni, "Roaccutane" impendulo yakhe kumagqirha kunye nezigulane zithetha iiveki 8. Ngoko ke, imfuneko kwakhona unyango-silubona kuphela emva kwexesha elingakanani na kwaye akazange amisiweyo.

Ngaba kukho i libanda?

Ukuba isigulane ligqithe ithamo okunikezelwe xa ezithatha ichiza "Roaccutane", imiyalelo ukusetyenziswa, angqina isigulane alatha ukuvela iimpawu hypervitaminosis vitamin A. Oku iyapheliswa ngokuhlamba isisu, apho kuyimfuneko uvelise kwiiyure zokuqala ezimbalwa emva kokuba amayeza isehlo nokusetyenziswa ngokugqithisileyo.

Ichiza esinxibelelana namanye amayeza?

Ngaxeshanye lolwamkelo esikolweni "Roaccutane" kunye vitamin A kukhokelela hypervitaminosis yokugqibela, ngoko olu dibaniso kufuneka kuphetshwe.

Contraindicated ngayo kunyango kunye isotretinoin kunye tetracyclines, njengoko kukhokelela ekwandeni koxinzelelo intracranial.

Lidla ukwehliswa impumelelo dlala, nto leyo ebangela iipilisi amaqhakuva "Roaccutane". Izimvo kumagqirha kubonisa ukuba unyango esi sixhobo kufuneka ingasetyenziswa Iipilisi zothintelo kukhulelwa kunye namaqondo hormone aphezulu kunye neendlela ukusetyenziswa umqobo yokucwangcisa.

Ukuba isigulana ezisebenzisayo unyango "Roaccutane" ekuhlaleni arhente keratolytic okanye exfoliants, kusenokuba kwinwebu ulusu.

Ngaba kunokwenzeka ukuba ukusebenzisa ichiza abafazi abakhulelweyo?

"Roaccutane" (amacwecwe, ncomo apho aphefumlelweyo impumelelo yabo ngokwakho abaninzi test) inomsebenzisi ebaluleke kakhulu: kokuba contraindicated ngokupheleleyo ngethuba lokukhulelwa. Isotretinoin na enamandla yaManzi naMahlathi. Unyango, nkqu amathamo emifutshane encinane amathuba aphezulu kunokubangela malformations ezinzulu Palsy.

Le nyaniso contraindication ngenxa beziyobisi ukuya namakhosikazi aselekhulile yokuzala abo musa ukuhlangabezana ezi khrayitheriya zilandelayo:

• Ubukho luhlobo kakhulu induna ukuba akukho kuphele kunyango oluqhelekileyo.

• Ibhinqa okuqonda kakuhle kwaye uthobela zonke iingcebiso gqirha.

• Yena yazisa ugqirha malunga ngeengozi lokukhulelwa ngexesha unyango "Roaccutane" kunye ngenyanga emva koko, imfuneko yokubonisana ezingxamisekileyo oyingcali kuthe enyanisweni kwesisu.

• Ibhinqa uyaziqonda unciphiso okanye ukulahleka lilonke ukusebenza zokucwangcisa.

• Yena uyaqonda eyona kunye nemfuneko yobukho ugqirha elikhankanywe amanyathelo othintelo.

• Umfazi uyayiqonda ukubaluleka ukhuseleko olungenasiphelo ekukhulelweni ekuhambeni unyango, inyanga ngaphambi nasemva kwakhe, kwakunye nemfuneko ukusebenzisa iindlela zombini 2 zokucwangcisa (kuquka umqobo).

• Umfazi uvavanyo result ukukhulelwa ezimbi ekufuneka lufunyanwe ngaphakathi kweentsuku ezili-11 phambi konyango. Kwakhona, le ukuxhaphaza kufuneka kwenziwe rhoqo ngenyanga ngexesha unyango kunye 5 kwiiveki nje emva kokuba igqityiwe.

• Kufuneka uqale ukufumana ichiza kuphela iiyure 2-3 emva ixesha oluqhelekileyo sexesheni.

• Ibhinqa ngokuyimfuneko kufuneka utyelele ugqirha nyanga zonke.

• Zonke ezi zinto zingasentla ezifanelekileyo kwizifundo ngokuphindaphindiweyo unyango "Roaccutane".

Qiniseka ukuba adibanisa kukhulelwa enokuthenjwa with "Roaccutane" ngeyeza induna. iingcali Guest alatha imfuneko bayigcine engqongqo imithetho abafazi bonke, kwanabo musa ukuthatha zokucwangcisa ngenxa yokungabi nenzalo, amenorrhea, bangavumi ukuba ukwabelana ngesondo. Ngaphandle kuphela isiguli waba hysterectomy izalwe.

Kufuneka kukhunjulwe ngugqirha?

Ugqirha kufuneka bazazi ezinye izibakala imo nomonde phambi kokuba unyango ukumisela "Roaccutane 'yakhe. iingcali Guest lubonisa ukuba ukuze aphephe iimeko ebezingalindelekanga, ugqirha kufuneka uqinisekise ngokupheleleyo zikhundla zilandelayo:

• I-isigulana uhlobo ngokwenene kakhulu induna ukuba asinyangeki yi ezinye iindlela zonyango, oko kukuthi nodulocystic okanye konglobatnye iziganeko ezikhokelela loloyiko.

• Abasetyhini yoko lokukhulelwa uvavanyo ezimbi sathathwa phambi kokuba kuyiwe ekhosini konyango, ngexesha unyango kunye 5 kwiiveki nje emva kokuba igqityiwe. Zonke ezi data kunye kubhalwe umhla zohlalutyo zibhalwa ngokungqongqo.

• Nomonde ngokuyimfuneko kuyasebenza nocwangciso (1, yaye ngokukhethekayo 2), indlela umqobo iyafuneka. Lo mthetho usebenza isithuba iinyanga phambi kokuba unyango, ikhondo kunye neentsuku ezingama-30 emva konyango.

• Ibhinqa ukuqonda ngokupheleleyo imfuneko ukuba athobele imiqathango zonke ukuthintela ukukhulelwa.

• Isigulana idibana zonke ezi mfuno zidwelisiweyo ngasentla.

Ingakumbi ukungabikho esweni lokukhulelwa

Kufuneka kuqatshelwe ukuba uvavanyo lokukhulelwa, ubuntununtunu 25 luphawulwa UMama / ml, kuyimfuneko ukuba uveze kwiintsuku zokuqala ezi-3 ukuba sexesheni.

Phambi kokuba kuyiwe ekhosini wenyanga isigulane kufuneka uqale ukuthatha zokucwangcisa. uvavanyo lokukhulelwa ngomhla kokuqeshwa, "Roaccutane", umhla kunye nogqirha kubangela kubhaliwe kumaxwebhu.

Ngexesha unyango, isigulane kufuneka ukutyelela ugqirha zonke iintsuku 28 kunye itsheki olusisinyanzelo ukungabikho lokukhulelwa. Uvavanyo olufanayo yenziwa emva kweeveki 5 ekupheleni unyango.

"Roaccutane" angqina nomonde Othetha malunga ukusebenza kwawo kwancamisa izithambiso, umiselwa ngokumiselwa kwaye kuphela kwithuba leentsuku ezingama-30. Ukuba ufuna ukuqhubekeka unyango, kucetyiswa ukuba ukuphinda uvavanyo lokukhulelwa.

Xana ndzi nga wu amadoda amayeza?

unyango amaqhakuva for "Roaccutane" amadoda isiyobisi kufanelekile, kodwa isigulane kufuneka nikunyamekele ecaleni ukwamkelwa ichiza ngabanye abantu. Ukungakhuseleki ichiza kulwelo ZakwaLizwi iphantsi yaye ayikho nako ukubonisa iipropati yaManzi naMahlathi.

Indlela ukucwangcisa i ukukhulelwa?

abafazi abaninzi ningaxhaleli ukuba nothetha ngakuphi na ukumitha kwakho kuya kuqhubeka emva "Roaccutane". Izimvo kumagqirha zibonisa ukuba isicwangciso ukukhulelwa nga zingaqali ngaphambi ngaphezu kwenyanga enye emva kokuphela kwekhosi epheleleyo yonyango.

Ukuba ngokuthobela onke amanyathelo ukukhulelwa ixesha eyingozi, lo mfazi kufuneka bazazi ubukho basengozini enkulu yokuba iimfambilini CNS ezimbi kakhulu yenkqubo sentliziyo, ubuso kunye namadlala yonyango. Ngoko ke, ukuba umba wokulondoloza mntwana.

"Roaccutane" ichiza kufuneka kuthathwe ngabasetyhini ngexesha zisanyisa, njengoko ludlulele ubisi lwebele.

Buhle zimaxongo zenzeke?

Kukho kakhulu inani elikhulu yeziphumo ebezingalindelekanga ezinokuthi zenzeke kule isigulane usebenzisa i "Roaccutane" iziyobisi. Imiyalelo, nokubuyekezwa ngamagqirha kunye nezigulane zithetha neziphumo ezingathandekiyo zilandelayo:

• Depression, ukwanda koxinzelelo intracranial, intloko ebuhlungu, ukuxhuzula.

• Ukunciphisa ubuzaza emini kunye nombono ungcwalazi, isifo samehlo, ukungase-.

• ukunyhashwa isitulo, isicaphucaphu, isifo wamathumbu kwiintetho ezikralayo, pancreatitis, ukopha.

• Anemia, utshintsho ukubala zegazi, umyinge neentlenge erythrocyte, hematocrit, neutropenia kunye leucopenia.

• bronchospasm.

• Ubuhlungu amalungu kunye nezihlunu, hyperostosis, tendonitis, samathambo.

• irhashalala, erythema, ukurhawuzelela, ukubila, nombala, ukuxozwa kunye nelahleko iinwele, photoallergy.

• isikhumba Dry kunye kwiinwebu imilebe, impumlo, pharynx kunye kwingqula, amehlo.

• utshintsho parameters elebhu: ukuphakamisa umgangatho cholesterol, triglycerides, lipoprotein, hyperglycemia.

• Systemic okanye wengingqi usuleleko streptococcal.

• hematuria, vasculitis, hypersensitivity, lymphadenopathy.

• Stevens-Johnson syndrome, multiforme erythema, ityhefu epidermal necrolysis.

Le ichiza contraindicated?

"Roaccutane" isiyobisi contraindicated kwi izifo kunye miqathango ilandelayo:

• Uhlobo Hyperlipidemia nkulumo.

• Ukukhulelwa kunye zisanyisa.

• Hypervitaminosis A.

• amachiza Therapy tetracycline.

• ukusilela Isibindi.

• inqanaba Ukwanda uvakalelo ichiza.

• Abantwana ukuya kwiminyaka engama-12.

Kabi care esebenzayo elawulwa nomntu ogulayo seswekile, butywala, ukuphazamiseka lipid, ukudandatheka kunye nokutyeba kakhulu.

Ukusebenza eli chiza ayikho kwamathandabuzo. "Roaccutane", ncomo, iifoto kunye okuvelayo zona zingqina ukuba ukubonakaliswa yayo nanto zonyango kunye izithambiso, usenza sibe nentembelo ekunyangeni amaqhakuva, nkqu iifomu bumandundu. Noko ke, zihlale zinolwazi ngazo zonke iziphumo ebezingalindelekanga ichiza elo azingqinelani ukukhulelwa kunye zisanyisa, kwakunye ubukho eziliqela Izimo. Injongo yale ichiza kwenziwa kuphela igqirha khona, ngubani omisa idosi ngamnye nomonde ixesha unyango.