"Truksal": ukuphononongwa koogqirha. "Truksal": imiyalelo yokusetyenziswa, imiphumo emibi

Abantu abambalwa kakhulu bayazi, kodwa ingqondo, i-neuroses kunye neentlungu eziphazamisayo zilungele ukunyango lweziyobisi. Into eyona nto kukuguqula ixesha kwi-expert specialist kwaye ulandele ngqo iziphakamiso zakhe.

Njengomthetho, kwiimeko ezinjalo, izigulane zichazwe izidakamizwa ze-antipsychotic okanye okuthiwa yi-neuroleptics. Ziyanciphisa kakhulu iimpawu zeengxaki zengqondo, kubuyela kwisigulana ingqondo ecacileyo kunye nokucinga okucacileyo.

Ngokuqhelekileyo, ngezifo ezikhankanywe ngasentla, unyango olunjenge "Truksal" lubekwe. Izikhokelo, ukubuyekezwa, iimpendulo ezingathandekiyo kunye nokuchasene kwesi siza kuya kuchazwa ngezantsi.

Ifomu, inkcazo, ukupakishwa kunye nokwakhiwa

Iyeza "Truksal" (ukugqithwa koogqirha malunga nalo kuya kuchazwa ekupheleni kwinqaku) kukhutshwa ngefomathi ezibomvu zemibala ejikelezayo kunye ne-biconcave, ehlanganiswe ngumboniso wefilimu.

Ukulungiselela umbuzo uqulethe isithako esisebenzayo njengechlorproticene hydrochloride. Kwakhona kubandakanye izongezo ezongezelelweyo ngendlela yesitashi, i-copovidone, i-lactose monohydrate, i-glycerol, i-cellulose microcrystalline, i-talc, i-croscarmellose i-sodium kunye ne-magnesium stearate.

Ngokubhekisele kumlenze wefilimu, uqukethe i-hypromellose, i-macrogol 400, i-red iron oxide, i-black iron oxide kunye ne-titanium dioxide.

Kukuphi ukupakisha iipilisi "Truksal" ezithengiswayo? Iingxelo zempendulo zabathengi ukuba kwi-shelf shelf idilesi zifumaneka kwiipakethi zekhadibhodi ezineengxowa zeplastiki.

Impembelelo yesilwanyana

Yintoni iTruksal? Iingcali zithi le nkunkuma esebenzayo. Ingozi ye-antipsychotic (oko kukuthi, i-antipsychotic) kwaye ivela kwi-thioxanthene.

Eli nyanga liyakwazi ukuba ne-moderation anti-depressant, i-sedative, kunye ne-antipsychotic effect.

Impahla yokugqibela yesilwanyana ngenxa yokukwazi ukuvimba i-dopamine receptors. Ngeli nyathelo lonyango, iimpembelelo zaso kunye ne-antiemetic nazo zihlobene.

Ngokomyalelo oqhotyoshelweyo, "i-Truksal", ekuhlaziywa kwayo okungahambi kakuhle, iyakwazi ukuvimba kuphela i-alpha-1-adrenergic receptors kunye ne-serotonin 5-HT2 receptors, kodwa i-histamine H1 receptors. Oku kubangela i-antihistamine yayo, i-hypotensive kunye ne-adrenoblocking action.

I-Kinetics yeziyobisi

Ingaba isilwanyana "Truksal" sithatha? Impendulo evela kubathengi abayi kuphendula impendulo. Emva kwayo kuya kufuneka ubhekisele kwimimiselo okanye kwizakhono zengcali. Ngokutsho kwabo, emva kokuthatha amachiza ngaphakathi, i-chlorprotixen ifakwa ngokukhawuleza kwindlela yokugaya.

Egazini, ukuxinwa okuphezulu kwezinto ezisetyenziswayo kugcinwa emva kwemizuzu eyi-120. Ukufumaneka kwe-drug is 12%.

Kufuneka kwakhona kuqaphele ukuba i-chlorprotixen ifikeleleke ngokukhawuleza inqamle isithintelo se-placental, kwaye ikhutshwe ngemali encinci kunye nobisi.

Isiqingatha-nobomi beli cilisi li-16 iiyure. I-metabolites eyiphumela ayinayo imisebenzi ye-neuroleptic. Ziye zaxutywa kunye nemifuno kunye nomchamo.

Iinkcazo

Ngaphantsi kweemeko ziphi iipilisi "Truksal" ezibonisiweyo? Oogqirha bathi ukuphumelela kwale mayeza kuthethwa kakhulu ngala macala alandelayo:

• Isifo sokuzilahla kunye nokuxilwa kweziyobisi kunye nokusetyenziswa kakubi kotywala;
• Iingqondo, kubandakanywa izimo zomntu, i-schizophrenia, ukukhathazeka kwengqondo, ukuphazamiseka nokuxhalaba;
• Ukuziphatha kakubi kubantwana;
• Ukungahambi kakuhle, ukuphazamiseka, ukucaphuka, ukudideka kwabalupheleyo;
• Ukuqhawula;
• Amazwe acinezelekileyo, iingxaki ze-psychosomatic kunye neuroses;
• I-syndrome ye-Pain (ngokudibanisa nama-analgesics).

Ukungqinelana

Ngokwemiyalelo, ukulawulwa kwe-neuroleptic "iTruksal" kuyaphikisana xa:

• Pheochromocytoma;
• Iimeko zokuqubana ;
• Ukunyanzeliswa kwinkqubo yesantya ephakathi yemvelaphi eyahlukeneyo (kubandakanywa nokusela kotywala, i-opioid analgesics kunye ne-barbiturates);
• Izifo ze-hematopoiesis;
• Ukuncelisa;
• Ukuwa kweenhliziyo;
• Ukukhulelwa;
• Ukunyanzeliswa kwemvelo kwizithako zeziyobisi.

Iibhilethi "Truksal": imiyalelo yokusetyenziswa

Iingcali zithi le mayeza kufuneka asetyenziswe kuphela ngenjongo yodokotela onolwazi. Ngaphandle koko, ukumkelwa kwawo okungalawulekiyo kunokufaka isandla ekuphuhliseni iintlobo ezahlukeneyo zokusabela okungathandekiyo.

Umlinganiselo walolu cwangciso luxhomekeke kuhlobo lwesifo.

Kwiengqondo, kunye nesimo se-schizophrenia kunye neemeko zokungcolisa ekuqaleni kwonyango unyango linikeze kumyinge we-50-100 mg ngosuku. Ngaphezulu, isixa sonyango sinyuka sibe ngu-300 mg ngosuku (ngamanye amaxesha ukuya kwi-1200 mg). Le dosi ihlukaniswe ngama-3 ahlukeneyo.

Xa unyango lweempawu zokurhoxiswa kunye nokusetyenziswa kotywala okungapheliyo, umthamo wansuku zonke wezilwanyana kufuneka ube ngu-500 mg kwizilwanyana ezintathu ezihlukeneyo. Inkqubo yonyango enye iveki.

Ekhulile, phambi kokuphoxeka, ukuphazamiseka, ukuxhatshazwa okanye ukudideka, unyango lunqunywe kwisixamali se-15-90 mg ngosuku (kwizigaba ezintathu ezihlukeneyo).

Abantwana ukulungelelanisa ukuphulwa ekuphatheni kweziyobisi ezinikezwe kwisilinganiso se-0.5-2 mg nganye ngekgithi yesisindo somzimba.

Ngeentlupheko ezidibaniswe noxinzelelo kunye nokuxhalabisa, iipilisi zeTruksal zingasetyenziswa zombini njenge-monotherapy kwaye njengelinye isilungiso esilongezelelweyo samachiza okuxhatshazwayo.

Ngeengxaki zengqondo kunye neuroses ezihambelana nokuphazamiseka kwengxaki kunye nokuxhalabisa, amayeza anconywa ukuba alawulwe kwiqondo lokufikelela kwi-90 mg ngosuku (kwizigaba ezintathu ezihlukeneyo).

Ngenxa yokuba le nkunkuma ayiyilanga okanye iyilwa, ingasetyenziswa ixesha elide.

Ngenxa yokulala, iipilisi zimiselwe i-20-30 mg ngokuhlwa kunye neyure enye ngaphambi kokulala.

Isiza "Truksal": ukuphononongwa, iziphumo ezibi

Njenganoma yiyiphi na i-antipsychotics, isicatshulwa esibuzwayo sivame ukubangelwa yimiphumo emibi :

• Ukulala, iimpawu ze-extrapyramidal, utywala, ukuphazamiseka kokuhlala;
• Tachycardia, hypotension orthostatic ;
• Umlomo owomileyo, i-jaundice ye-cholestatic, ukuqotshwa;
• I-Dysmenorrhea, ukuphazamiseka kwe-potency, i-galactorrhea;
• Ukwandisa ubunzima bomzimba, ukwandisa ukujuluka, ukwandisa ukutya;
• Inemia ye-anemia hemolytic, i-leukopenia ephazamisayo emfutshane;
• Ukuqhekeka kwezikhumba.

Uphononongo malunga nesi sixhobo siphezulu. Ngokuqhelekileyo kuboniswa ngabaama-bantwana abaneengxaki zokuziphatha. Bathetha ukuba le chiza aliyisebenzisi.

Ngokumalunga noogqirha, iimpendulo zabo azikho. Kuzo ezikhoyo, sinokugqiba ngokugqibeleleyo ukuba le nkunkuma kwimeko nganye ibonisa umphumo ohlukileyo.